Ambulant erworbene bakterielle Meningoenzephalitis: Die neue Leitlinie
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Ambulant erworbene bakterielle Meningoenzephalitis: Die neue Leitlinie. / Hadjilaou, Alexandros; Friese, Manuel Alexander.
In: DEUT MED WOCHENSCHR, Vol. 149, No. 17, 08.2024, p. 1021-1027.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Ambulant erworbene bakterielle Meningoenzephalitis: Die neue Leitlinie
AU - Hadjilaou, Alexandros
AU - Friese, Manuel Alexander
N1 - Thieme. All rights reserved.
PY - 2024/8
Y1 - 2024/8
N2 - Updating the vaccination recommendations against meningococci and pneumococci, in particular the introduction of the B vaccine as the standard vaccination for infants from January 2024 and the adaptation of the pneumococcal vaccination strategy for infants and adults aged 60 and over with the latest conjugate vaccines (PCV13, PCV15, PCV20).Emphasis on the need for rapid diagnostic lumbar puncture and simultaneous serum and cerebrospinal fluid analysis to increase diagnostic precision. The introduction of procalcitonin (PCT) in serum as an additional biomarker to differentiate between bacterial and viral meningitis.The use of multiplex PCR as a supplement, not a replacement, for standard diagnostics to speed up pathogen identification.Adaptation of antibiotic recommendations based on the current resistance situation, in particular for meningococcal meningitis, consideration of penicillin G only after resistance testing.Clarification of the areas and duration of use of dexamethasone in bacterial meningitis, particularly in pneumococcal meningitis and the controversial data situation in Listeria meningitis.New findings on the safe use of heparin in septic sinus thrombosis without increased risk of hemorrhage.
AB - Updating the vaccination recommendations against meningococci and pneumococci, in particular the introduction of the B vaccine as the standard vaccination for infants from January 2024 and the adaptation of the pneumococcal vaccination strategy for infants and adults aged 60 and over with the latest conjugate vaccines (PCV13, PCV15, PCV20).Emphasis on the need for rapid diagnostic lumbar puncture and simultaneous serum and cerebrospinal fluid analysis to increase diagnostic precision. The introduction of procalcitonin (PCT) in serum as an additional biomarker to differentiate between bacterial and viral meningitis.The use of multiplex PCR as a supplement, not a replacement, for standard diagnostics to speed up pathogen identification.Adaptation of antibiotic recommendations based on the current resistance situation, in particular for meningococcal meningitis, consideration of penicillin G only after resistance testing.Clarification of the areas and duration of use of dexamethasone in bacterial meningitis, particularly in pneumococcal meningitis and the controversial data situation in Listeria meningitis.New findings on the safe use of heparin in septic sinus thrombosis without increased risk of hemorrhage.
KW - Humans
KW - Community-Acquired Infections/diagnosis
KW - Meningoencephalitis/diagnosis
KW - Anti-Bacterial Agents/therapeutic use
KW - Infant
KW - Practice Guidelines as Topic
KW - Adult
KW - Middle Aged
KW - Meningitis, Bacterial/diagnosis
KW - Procalcitonin/blood
KW - Meningococcal Vaccines/therapeutic use
U2 - 10.1055/a-2204-5167
DO - 10.1055/a-2204-5167
M3 - SCORING: Zeitschriftenaufsatz
C2 - 39146749
VL - 149
SP - 1021
EP - 1027
JO - DEUT MED WOCHENSCHR
JF - DEUT MED WOCHENSCHR
SN - 0012-0472
IS - 17
ER -