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Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy

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Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy. / McCubrey, James A; Sokolosky, Melissa L; Lehmann, Brian D; Taylor, Jackson R; Navolanic, Patrick M; Chappell, William H; Abrams, Stephen L; Stadelman, Kristin M; Wong, Ellis W T; Misaghian, Negin; Horn, Stefan; Bäsecke, Jörg; Libra, Massimo; Stivala, Franca; Ligresti, Giovanni; Tafuri, Agostino; Milella, Michele; Zarzycki, Marek; Dzugaj, Andrzej; Chiarini, Francesca; Evangelisti, Camilla; Martelli, Alberto M; Terrian, David M; Franklin, Richard A; Steelman, Linda S.

In: Advances in enzyme regulation, Vol. 48, 01.01.2008, p. 113-35.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

McCubrey, JA, Sokolosky, ML, Lehmann, BD, Taylor, JR, Navolanic, PM, Chappell, WH, Abrams, SL, Stadelman, KM, Wong, EWT, Misaghian, N, Horn, S, Bäsecke, J, Libra, M, Stivala, F, Ligresti, G, Tafuri, A, Milella, M, Zarzycki, M, Dzugaj, A, Chiarini, F, Evangelisti, C, Martelli, AM, Terrian, DM, Franklin, RA & Steelman, LS 2008, 'Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy', Advances in enzyme regulation, vol. 48, pp. 113-35. https://doi.org/10.1016/j.advenzreg.2008.02.006

APA

McCubrey, J. A., Sokolosky, M. L., Lehmann, B. D., Taylor, J. R., Navolanic, P. M., Chappell, W. H., Abrams, S. L., Stadelman, K. M., Wong, E. W. T., Misaghian, N., Horn, S., Bäsecke, J., Libra, M., Stivala, F., Ligresti, G., Tafuri, A., Milella, M., Zarzycki, M., Dzugaj, A., ... Steelman, L. S. (2008). Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy. Advances in enzyme regulation, 48, 113-35. https://doi.org/10.1016/j.advenzreg.2008.02.006

Vancouver

McCubrey JA, Sokolosky ML, Lehmann BD, Taylor JR, Navolanic PM, Chappell WH et al. Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy. Advances in enzyme regulation. 2008 Jan 1;48:113-35. https://doi.org/10.1016/j.advenzreg.2008.02.006

Bibtex

@article{3a1fcb4b7ce84366b941dd47b4476db7,
title = "Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy",
keywords = "Antineoplastic Agents, Hormonal, Antineoplastic Combined Chemotherapy Protocols, Apoptosis, Breast Neoplasms, Cell Aging, Cell Cycle, Cell Transformation, Neoplastic, Doxorubicin, Drug Resistance, Neoplasm, Extracellular Signal-Regulated MAP Kinases, Female, Humans, Metabolic Networks and Pathways, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Protein Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction, TOR Serine-Threonine Kinases, Tumor Cells, Cultured, raf Kinases",
author = "McCubrey, {James A} and Sokolosky, {Melissa L} and Lehmann, {Brian D} and Taylor, {Jackson R} and Navolanic, {Patrick M} and Chappell, {William H} and Abrams, {Stephen L} and Stadelman, {Kristin M} and Wong, {Ellis W T} and Negin Misaghian and Stefan Horn and J{\"o}rg B{\"a}secke and Massimo Libra and Franca Stivala and Giovanni Ligresti and Agostino Tafuri and Michele Milella and Marek Zarzycki and Andrzej Dzugaj and Francesca Chiarini and Camilla Evangelisti and Martelli, {Alberto M} and Terrian, {David M} and Franklin, {Richard A} and Steelman, {Linda S}",
year = "2008",
month = jan,
day = "1",
doi = "10.1016/j.advenzreg.2008.02.006",
language = "English",
volume = "48",
pages = "113--35",

}

RIS

TY - JOUR

T1 - Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy

AU - McCubrey, James A

AU - Sokolosky, Melissa L

AU - Lehmann, Brian D

AU - Taylor, Jackson R

AU - Navolanic, Patrick M

AU - Chappell, William H

AU - Abrams, Stephen L

AU - Stadelman, Kristin M

AU - Wong, Ellis W T

AU - Misaghian, Negin

AU - Horn, Stefan

AU - Bäsecke, Jörg

AU - Libra, Massimo

AU - Stivala, Franca

AU - Ligresti, Giovanni

AU - Tafuri, Agostino

AU - Milella, Michele

AU - Zarzycki, Marek

AU - Dzugaj, Andrzej

AU - Chiarini, Francesca

AU - Evangelisti, Camilla

AU - Martelli, Alberto M

AU - Terrian, David M

AU - Franklin, Richard A

AU - Steelman, Linda S

PY - 2008/1/1

Y1 - 2008/1/1

KW - Antineoplastic Agents, Hormonal

KW - Antineoplastic Combined Chemotherapy Protocols

KW - Apoptosis

KW - Breast Neoplasms

KW - Cell Aging

KW - Cell Cycle

KW - Cell Transformation, Neoplastic

KW - Doxorubicin

KW - Drug Resistance, Neoplasm

KW - Extracellular Signal-Regulated MAP Kinases

KW - Female

KW - Humans

KW - Metabolic Networks and Pathways

KW - PTEN Phosphohydrolase

KW - Phosphatidylinositol 3-Kinases

KW - Protein Kinases

KW - Proto-Oncogene Proteins c-akt

KW - Signal Transduction

KW - TOR Serine-Threonine Kinases

KW - Tumor Cells, Cultured

KW - raf Kinases

U2 - 10.1016/j.advenzreg.2008.02.006

DO - 10.1016/j.advenzreg.2008.02.006

M3 - SCORING: Journal article

C2 - 18423407

VL - 48

SP - 113

EP - 135

ER -