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A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion

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A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion. / Becerikli, Mustafa; Kopp, Alexander; Kröger, Nadja; Bodrova, Mariia; Wallner, Christoph; Wagner, Johannes Maximilian; Dadras, Mehran; Jettkant, Birger; Pöhl, Fabian; Lehnhardt, Marcus; Jung, Ole; Behr, Björn.

In: MAT SCI ENG C-MATER, Vol. 123, 112030, 04.2021.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Becerikli, M, Kopp, A, Kröger, N, Bodrova, M, Wallner, C, Wagner, JM, Dadras, M, Jettkant, B, Pöhl, F, Lehnhardt, M, Jung, O & Behr, B 2021, 'A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion', MAT SCI ENG C-MATER, vol. 123, 112030. https://doi.org/10.1016/j.msec.2021.112030

APA

Becerikli, M., Kopp, A., Kröger, N., Bodrova, M., Wallner, C., Wagner, J. M., Dadras, M., Jettkant, B., Pöhl, F., Lehnhardt, M., Jung, O., & Behr, B. (2021). A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion. MAT SCI ENG C-MATER, 123, [112030]. https://doi.org/10.1016/j.msec.2021.112030

Vancouver

Becerikli M, Kopp A, Kröger N, Bodrova M, Wallner C, Wagner JM et al. A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion. MAT SCI ENG C-MATER. 2021 Apr;123. 112030. https://doi.org/10.1016/j.msec.2021.112030

Bibtex

@article{ef6d9bd9c05549b0b1bdab61a633b0ec,
title = "A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion",
abstract = "Titanium is one of the most commonly used materials for implants in trauma applications due to its low density, high corrosion resistance and biocompatibility. Nevertheless, there is still a need for improved surface modifications of Titanium, in order to change surface properties such as wettability, antibacterial properties or tissue attachment. In this study, different novel plasma electrolytic oxidation (PEO) modifications have been investigated for tendon adhesion to implants commonly used in hand surgery. Titanium samples with four different PEO modifications were prepared by varying the electrolyte composition and analyzed with regards to their surface properties. Unmodified titanium blanks and Dotize{\textregistered} coating served as controls. Samples were examined using scanning electron microscopy (SEM), energy dispersive spectrometer (EDS), contact angle measuring system and analyzed for their biocompatibility and hemocompatibility (according to DIN ISO 10993-5 and 10,993-4). Finally, tendon adhesion of these specific surfaces were investigated by pull-off tests. Our findings show that surface thickness of PEO modifications was about 12-20 μm and had porous morphology. One modification demonstrated hydrophilic behavior accompanied by good biocompatibility without showing cytotoxic properties. Furthermore, no hemolytic effect and no significant influence on hemocompatibility were observed. Pull-off tests revealed a significant reduction of tendon adhesion by 64.3% (35.7% residual adhesion), compared to unmodified titanium (100%). In summary, the novel PEO-based ceramic-like porous modification for titanium surfaces might be considered a good candidate for orthopedic applications supporting a more efficient recovery.",
author = "Mustafa Becerikli and Alexander Kopp and Nadja Kr{\"o}ger and Mariia Bodrova and Christoph Wallner and Wagner, {Johannes Maximilian} and Mehran Dadras and Birger Jettkant and Fabian P{\"o}hl and Marcus Lehnhardt and Ole Jung and Bj{\"o}rn Behr",
note = "Copyright {\textcopyright} 2021 Elsevier B.V. All rights reserved.",
year = "2021",
month = apr,
doi = "10.1016/j.msec.2021.112030",
language = "English",
volume = "123",
journal = "MAT SCI ENG C-MATER",
issn = "0928-4931",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - A novel titanium implant surface modification by plasma electrolytic oxidation (PEO) preventing tendon adhesion

AU - Becerikli, Mustafa

AU - Kopp, Alexander

AU - Kröger, Nadja

AU - Bodrova, Mariia

AU - Wallner, Christoph

AU - Wagner, Johannes Maximilian

AU - Dadras, Mehran

AU - Jettkant, Birger

AU - Pöhl, Fabian

AU - Lehnhardt, Marcus

AU - Jung, Ole

AU - Behr, Björn

N1 - Copyright © 2021 Elsevier B.V. All rights reserved.

PY - 2021/4

Y1 - 2021/4

N2 - Titanium is one of the most commonly used materials for implants in trauma applications due to its low density, high corrosion resistance and biocompatibility. Nevertheless, there is still a need for improved surface modifications of Titanium, in order to change surface properties such as wettability, antibacterial properties or tissue attachment. In this study, different novel plasma electrolytic oxidation (PEO) modifications have been investigated for tendon adhesion to implants commonly used in hand surgery. Titanium samples with four different PEO modifications were prepared by varying the electrolyte composition and analyzed with regards to their surface properties. Unmodified titanium blanks and Dotize® coating served as controls. Samples were examined using scanning electron microscopy (SEM), energy dispersive spectrometer (EDS), contact angle measuring system and analyzed for their biocompatibility and hemocompatibility (according to DIN ISO 10993-5 and 10,993-4). Finally, tendon adhesion of these specific surfaces were investigated by pull-off tests. Our findings show that surface thickness of PEO modifications was about 12-20 μm and had porous morphology. One modification demonstrated hydrophilic behavior accompanied by good biocompatibility without showing cytotoxic properties. Furthermore, no hemolytic effect and no significant influence on hemocompatibility were observed. Pull-off tests revealed a significant reduction of tendon adhesion by 64.3% (35.7% residual adhesion), compared to unmodified titanium (100%). In summary, the novel PEO-based ceramic-like porous modification for titanium surfaces might be considered a good candidate for orthopedic applications supporting a more efficient recovery.

AB - Titanium is one of the most commonly used materials for implants in trauma applications due to its low density, high corrosion resistance and biocompatibility. Nevertheless, there is still a need for improved surface modifications of Titanium, in order to change surface properties such as wettability, antibacterial properties or tissue attachment. In this study, different novel plasma electrolytic oxidation (PEO) modifications have been investigated for tendon adhesion to implants commonly used in hand surgery. Titanium samples with four different PEO modifications were prepared by varying the electrolyte composition and analyzed with regards to their surface properties. Unmodified titanium blanks and Dotize® coating served as controls. Samples were examined using scanning electron microscopy (SEM), energy dispersive spectrometer (EDS), contact angle measuring system and analyzed for their biocompatibility and hemocompatibility (according to DIN ISO 10993-5 and 10,993-4). Finally, tendon adhesion of these specific surfaces were investigated by pull-off tests. Our findings show that surface thickness of PEO modifications was about 12-20 μm and had porous morphology. One modification demonstrated hydrophilic behavior accompanied by good biocompatibility without showing cytotoxic properties. Furthermore, no hemolytic effect and no significant influence on hemocompatibility were observed. Pull-off tests revealed a significant reduction of tendon adhesion by 64.3% (35.7% residual adhesion), compared to unmodified titanium (100%). In summary, the novel PEO-based ceramic-like porous modification for titanium surfaces might be considered a good candidate for orthopedic applications supporting a more efficient recovery.

U2 - 10.1016/j.msec.2021.112030

DO - 10.1016/j.msec.2021.112030

M3 - SCORING: Journal article

C2 - 33812645

VL - 123

JO - MAT SCI ENG C-MATER

JF - MAT SCI ENG C-MATER

SN - 0928-4931

M1 - 112030

ER -