A new Bayesian model applied to cytogenetic partial body irradiation estimation

  • Manuel Higueras
  • Pedro Puig
  • Elizabeth A Ainsbury
  • Volodymyr A Vinnikov
  • Kai Rothkamm

Abstract

A new zero-inflated Poisson model is introduced for the estimation of partial body irradiation dose and fraction of body irradiated. The Bayes factors are introduced as tools to help determine whether a data set of chromosomal aberrations obtained from a blood sample reflects partial or whole body irradiation. Two examples of simulated cytogenetic radiation exposure data are presented to demonstrate the usefulness of this methodology in cytogenetic biological dosimetry.

Bibliographical data

Original languageEnglish
ISSN0144-8420
DOIs
Publication statusPublished - 03.2016
PubMed 26065702