A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment.

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A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment. / Kiefer, F; Jahn, Holger; Wiedemann, Klaus.

In: PHARMACOPSYCHIATRY, Vol. 38, No. 4, 4, 2005, p. 184-186.

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@article{40538c24ad9b4e5d852710d457a907a3,
title = "A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment.",
abstract = "The ability of naltrexone to increase hypothalamo-pituitary-adrenocortical (HPA)-axis activity was recently reported to be associated with its effects on the reduction of craving for alcohol. We now present data showing naltrexone to be more efficacious in female alcoholics. Since HPA-axis might be interpreted as a key mechanism of action that could explain the observed gender differences in the abstinence maintenance treatment of alcohol addiction.",
author = "F Kiefer and Holger Jahn and Klaus Wiedemann",
year = "2005",
language = "Deutsch",
volume = "38",
pages = "184--186",
journal = "PHARMACOPSYCHIATRY",
issn = "0176-3679",
publisher = "Georg Thieme Verlag KG",
number = "4",

}

RIS

TY - JOUR

T1 - A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment.

AU - Kiefer, F

AU - Jahn, Holger

AU - Wiedemann, Klaus

PY - 2005

Y1 - 2005

N2 - The ability of naltrexone to increase hypothalamo-pituitary-adrenocortical (HPA)-axis activity was recently reported to be associated with its effects on the reduction of craving for alcohol. We now present data showing naltrexone to be more efficacious in female alcoholics. Since HPA-axis might be interpreted as a key mechanism of action that could explain the observed gender differences in the abstinence maintenance treatment of alcohol addiction.

AB - The ability of naltrexone to increase hypothalamo-pituitary-adrenocortical (HPA)-axis activity was recently reported to be associated with its effects on the reduction of craving for alcohol. We now present data showing naltrexone to be more efficacious in female alcoholics. Since HPA-axis might be interpreted as a key mechanism of action that could explain the observed gender differences in the abstinence maintenance treatment of alcohol addiction.

M3 - SCORING: Zeitschriftenaufsatz

VL - 38

SP - 184

EP - 186

JO - PHARMACOPSYCHIATRY

JF - PHARMACOPSYCHIATRY

SN - 0176-3679

IS - 4

M1 - 4

ER -