A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment.
Standard
A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment. / Kiefer, F; Jahn, Holger; Wiedemann, Klaus.
in: PHARMACOPSYCHIATRY, Jahrgang 38, Nr. 4, 4, 2005, S. 184-186.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - A neuroendocrinological hypothesis on gender effects of naltrexone in relapse prevention treatment.
AU - Kiefer, F
AU - Jahn, Holger
AU - Wiedemann, Klaus
PY - 2005
Y1 - 2005
N2 - The ability of naltrexone to increase hypothalamo-pituitary-adrenocortical (HPA)-axis activity was recently reported to be associated with its effects on the reduction of craving for alcohol. We now present data showing naltrexone to be more efficacious in female alcoholics. Since HPA-axis might be interpreted as a key mechanism of action that could explain the observed gender differences in the abstinence maintenance treatment of alcohol addiction.
AB - The ability of naltrexone to increase hypothalamo-pituitary-adrenocortical (HPA)-axis activity was recently reported to be associated with its effects on the reduction of craving for alcohol. We now present data showing naltrexone to be more efficacious in female alcoholics. Since HPA-axis might be interpreted as a key mechanism of action that could explain the observed gender differences in the abstinence maintenance treatment of alcohol addiction.
M3 - SCORING: Zeitschriftenaufsatz
VL - 38
SP - 184
EP - 186
JO - PHARMACOPSYCHIATRY
JF - PHARMACOPSYCHIATRY
SN - 0176-3679
IS - 4
M1 - 4
ER -