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5-lipoxygenase mRNA and protein isoforms

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5-lipoxygenase mRNA and protein isoforms. / Ochs, Meike J; Suess, Beatrix; Steinhilber, Dieter.

In: BASIC CLIN PHARMACOL, Vol. 114, No. 1, 01.2014, p. 78-82.

Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

Harvard

Ochs, MJ, Suess, B & Steinhilber, D 2014, '5-lipoxygenase mRNA and protein isoforms', BASIC CLIN PHARMACOL, vol. 114, no. 1, pp. 78-82. https://doi.org/10.1111/bcpt.12115

APA

Ochs, M. J., Suess, B., & Steinhilber, D. (2014). 5-lipoxygenase mRNA and protein isoforms. BASIC CLIN PHARMACOL, 114(1), 78-82. https://doi.org/10.1111/bcpt.12115

Vancouver

Ochs MJ, Suess B, Steinhilber D. 5-lipoxygenase mRNA and protein isoforms. BASIC CLIN PHARMACOL. 2014 Jan;114(1):78-82. https://doi.org/10.1111/bcpt.12115

Bibtex

@article{fbca930f691a429197a003c51d50e6b0,
title = "5-lipoxygenase mRNA and protein isoforms",
abstract = "5-Lipoxygenase (5-LO) catalyses the two initial steps in the biosynthesis of leukotrienes, a group of inflammatory lipid mediators derived from arachidonic acid. An increased level of leukotrienes is associated with chronic inflammatory diseases such as asthma or atherosclerosis. In this MiniReview, we focus on recent findings regarding alternative splice variants of 5-LO with a special emphasis on two potential protein isoforms expressed in human B-lymphocytes which might be of interest as new drug targets.",
keywords = "Arachidonate 5-Lipoxygenase/genetics, B-Lymphocytes/metabolism, Gene Expression Regulation, Enzymologic, Humans, Leukotrienes/metabolism, Protein Isoforms/genetics, Proteome/genetics, RNA, Messenger/genetics",
author = "Ochs, {Meike J} and Beatrix Suess and Dieter Steinhilber",
note = "{\textcopyright} 2013 Nordic Pharmacological Society. Published by John Wiley & Sons Ltd.",
year = "2014",
month = jan,
doi = "10.1111/bcpt.12115",
language = "English",
volume = "114",
pages = "78--82",
journal = "BASIC CLIN PHARMACOL",
issn = "1742-7835",
publisher = "Wiley-Blackwell",
number = "1",

}

RIS

TY - JOUR

T1 - 5-lipoxygenase mRNA and protein isoforms

AU - Ochs, Meike J

AU - Suess, Beatrix

AU - Steinhilber, Dieter

N1 - © 2013 Nordic Pharmacological Society. Published by John Wiley & Sons Ltd.

PY - 2014/1

Y1 - 2014/1

N2 - 5-Lipoxygenase (5-LO) catalyses the two initial steps in the biosynthesis of leukotrienes, a group of inflammatory lipid mediators derived from arachidonic acid. An increased level of leukotrienes is associated with chronic inflammatory diseases such as asthma or atherosclerosis. In this MiniReview, we focus on recent findings regarding alternative splice variants of 5-LO with a special emphasis on two potential protein isoforms expressed in human B-lymphocytes which might be of interest as new drug targets.

AB - 5-Lipoxygenase (5-LO) catalyses the two initial steps in the biosynthesis of leukotrienes, a group of inflammatory lipid mediators derived from arachidonic acid. An increased level of leukotrienes is associated with chronic inflammatory diseases such as asthma or atherosclerosis. In this MiniReview, we focus on recent findings regarding alternative splice variants of 5-LO with a special emphasis on two potential protein isoforms expressed in human B-lymphocytes which might be of interest as new drug targets.

KW - Arachidonate 5-Lipoxygenase/genetics

KW - B-Lymphocytes/metabolism

KW - Gene Expression Regulation, Enzymologic

KW - Humans

KW - Leukotrienes/metabolism

KW - Protein Isoforms/genetics

KW - Proteome/genetics

KW - RNA, Messenger/genetics

U2 - 10.1111/bcpt.12115

DO - 10.1111/bcpt.12115

M3 - Short publication

C2 - 24020397

VL - 114

SP - 78

EP - 82

JO - BASIC CLIN PHARMACOL

JF - BASIC CLIN PHARMACOL

SN - 1742-7835

IS - 1

ER -