Wolfgang Deppert
Publications
- 2023
Basal-like mammary carcinomas stimulate cancer stem cell properties through AXL-signaling to induce chemotherapy resistance
Pantelaiou-Prokaki, G., Reinhardt, O., Georges, N. S., Agorku, D. J., Hardt, O., Prokakis, E., Mieczkowska, I. K., Deppert, W., Wegwitz, F. & Alves, F., 01.05.2023, In: INT J CANCER. 152, 9, p. 1916-1932 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Infiltration of Immune Competent Cells into Primary Tumors and Their Surrounding Connective Tissues in Xenograft and Syngeneic Mouse Models
Metzen, M., Bruns, M., Deppert, W. & Schumacher, U., 19.04.2021, In: INT J MOL SCI. 22, 8, p. 4213Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Immunotherapy of WAP-TNP mice with early stage mammary gland tumors
Bruns, M. & Deppert, W., 15.09.2017, In: ONCOTARGET. 8, 40, p. 67790-67804Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Cancer immunotherapy: weak beats strong
Deppert, W. & Bruns, M., 30.11.2016, In: AGING-US. 8, 11, p. 2607-2608 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo
Wegwitz, F., Lenfert, E., Gerstel, D., von Ehrenstein, L., Einhoff, J., Schmidt, G., Logsdon, M., Brandner, J., Tiegs, G., Beauchemin, N., Wagener, C., Deppert, W. & Horst, A. K., 27.09.2016, In: ONCOTARGET. 7, 39, p. 63730-63746Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy
Bruns, M., Wanger, J., Schumacher, U. & Deppert, W., 2016, In: ONCOTARGET. 7, 40, p. 64543 - 64559Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
An inducible transgenic mouse breast cancer model for the analysis of tumor antigen specific CD8+ T-cell responses
Bruns, M., Wanger, J., Utermöhlen, O. & Deppert, W., 17.11.2015, In: ONCOTARGET. 6, 36, p. 38487-503 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chemotherapy of WAP-T mouse mammary carcinomas aggravates tumor phenotype and enhances tumor cell dissemination
Jannasch, K., Wegwitz, F., Lenfert, E., Mänz, C., Deppert, W. & Alves, F., 01.07.2015, In: INT J CANCER. 137, 1, p. 25-36Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epithelial-mesenchymal plasticity is a decisive feature for the metastatic outgrowth of disseminated WAP-T mouse mammary carcinoma cells
Maenz, C., Lenfert, E., Pantel, K., Schumacher, U., Deppert, W. & Wegwitz, F., 01.01.2015, In: BMC CANCER. 15, p. 178Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutant p53 promotes epithelial-mesenchymal plasticity and enhances metastasis in mammary carcinomas of WAP-T mice
Lenfert, E., Mänz, C., Heinlein, C., Jannasch, K., Schumacher, U., Pantel, K., Tolstonog, G. V., Deppert, W. & Wegwitz, F., 2015, In: INT J CANCER. 136, 6, p. E521-E533Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Lectin histochemistry of murine WAP-T mammary cancer reveals similar glycoconjugate changes to those in human breast cancer
Schreiber, S., Gocht, A., Wegwitz, F., Deppert, W. & Schumacher, U., 01.12.2014, In: ANTICANCER RES. 34, 12, p. 7045-53 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Aberrant Proliferation of Differentiating Alveolar Cells Induces Hyperplasia in Resting Mammary Glands of SV40-TAg Transgenic Mice
Quante, T., Wegwitz, F., Abe, J., Rossi, A., Deppert, W. & Bohn, W., 01.01.2014, In: FRONT ONCOL. 4, p. 168Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
CEBP factors regulate telomerase reverse transcriptase promoter activity in whey acidic protein-T mice during mammary carcinogenesis
Kumar, M., Witt, B., Knippschild, U., Koch, S., Meena, J. K., Heinlein, C., Weise, J. M., Krepulat, F., Kuchenbauer, F., Iben, S., Rudolph, K-L., Deppert, W. & Günes, C., 01.05.2013, In: INT J CANCER. 132, 9, p. 2032-2043 12 p., 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcription factors link mouse WAP-T mammary tumors with human breast cancer
Otto, B., Streichert, T., Wegwitz, F., Gevensleben, H., Klätschke, K., Wagener, C., Deppert, W. & Tolstonog, G. V., 15.03.2013, In: INT J CANCER. 132, 6, p. 1311-1322 12 p., 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells
Brázdová, M., Navrátilová, L., Tichý, V., Němcová, K., Lexa, M., Hrstka, R., Pečinka, P., Adámik, M., Vojtesek, B., Paleček, E., Deppert, W. & Fojta, M., 01.01.2013, In: PLOS ONE. 8, 3, p. e59567Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel niche for skin derived precursors in non-follicular skin.
Ruetze, M., Knauer, T., Gallinat, S., Wenck, H., Achterberg, V., Maerz, A., Deppert, W. & Knott, A., 2013, In: J DERMATOL SCI. 69, 2, p. 132-139 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.
Otto, B., Gruner, K., Heinlein, C., Wegwitz, F., Nollau, P., Ylstra, B., Pantel, K., Schumacher, U., Baumbusch, L. O., Martin-Subero, J. I., Siebert, R., Wagener, C., Streichert, T., Deppert, W. & Tolstonog, G. V., 2013, In: INT J CANCER. 132, 6, p. 1300-1310 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Recombinant p53 displays heterogeneity during isoelectric focusing
Heukeshoven, J., März, A., Warnecke, G., Deppert, W. & Tolstonog, G. V., 09.2012, In: ELECTROPHORESIS. 33, 18, p. 2818-2827 10 p., 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell cycle regulator Cdkn1c (p57/KIP2) shows distinct expression in epidermal differentiation.
Hildebrand, J., Spörl, F., Korge, S., Gallinat, S., Wenck, H., Deppert, W., Knott, A. & Blatt, T., 2012, In: EUR J DERMATOL. 22, 5, p. 694-696 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants.
Hanjalic-Beck, A., Schäfer, W. R., Deppert, W., Fischer, L., Stein, A., Seebacher, L., Gradowski, V., Seli, A., Stuckenschneider, J. & Zahradnik, H. P., 2012, In: FERTIL STERIL. 98, 4, p. 1017-1022 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.
Hirner, H., Günes, C., Bischof, J., Wolff, S., Grothey, A., Kühl, M., Oswald, F., Wegwitz, F., Bösl, M. R., Trauzold, A., Henne-Bruns, D., Peifer, C., Leithäuser, F., Deppert, W. & Knippschild, U., 2012, In: PLOS ONE. 7, 1, p. 29709 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.
Quante, T., Otto, B., Brázdová, M., Kejnovská, I., Deppert, W. & Tolstonog, G. V., 2012, In: CELL CYCLE. 11, 17, p. 3290-3303 17.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutant p53 protein, master regulator of human malignancies: a report on the Fifth Mutant p53 Workshop.
Blandino, G., Deppert, W., Hainaut, P., Levine, A., Lozano, G., Olivier, M., Rotter, V., Wiman, K. & Oren, M., 2012, In: CELL DEATH DIFFER. 19, 1, p. 180-183 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Potential hazards to embryo implantation: A human endometrial in vitro model to identify unwanted antigestagenic actions of chemicals.
Fischer, L., Deppert, W., Pfeifer, D., Stanzel, S., Weimer, M., Hanjalic-Beck, A., Stein, A., Straßer, M., Zahradnik, H. P. & Schaefer, W. R., 2012, In: TOXICOL APPL PHARM. 260, 3, p. 232-240 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Metabolic sensing by p53: keeping the balance between life and death
Tolstonog, G. V. & Deppert, W., 27.07.2010, In: P NATL ACAD SCI USA. 107, 30, p. 13193-4 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Modulation of gene expression in U251 glioblastoma cells by binding of mutant p53 R273H to intronic and intergenic sequences
Brázdová, M., Quante, T., Tögel, L., Walter, K., Loscher, C., Tichý, V., Cincárová, L., Deppert, W. & Tolstonog, G. V., 04.2009, In: NUCLEIC ACIDS RES. 37, 5, p. 1486-500 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Cytoplasmic localization of wild-type p53 in glioblastomas correlates with expression of vimentin and glial fibrillary acidic protein
Sembritzki, O., Hagel, C., Lamszus, K., Deppert, W. & Bohn, W., 07.2002, In: NEURO-ONCOLOGY. 4, 3, p. 171-8 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1995
Emergence of virus escape mutants after immunization with epitope vaccine
Weidt, G., Deppert, W., Utermöhlen, O., Heukeshoven, J. & Lehmann-Grube, F., 11.1995, In: J VIROL. 69, 11, p. 7147-51 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review