PD Dr. med. ID: 43961
Tim Ullrich Magnus
Publications
- 2014
PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model
Low, P. C., Manzanero, S., Mohannak, N., Narayana, V. K., Nguyen, T. H., Kvaskoff, D., Brennan, F. H., Ruitenberg, M. J., Gelderblom, M., Magnus, T., Kim, H. A., Broughton, B. R. S., Sobey, C. G., Vanhaesebroeck, B., Stow, J. L., Arumugam, T. V. & Meunier, F. A., 2014, In: NAT COMMUN. 5, p. 3450Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load
Bogner, S., Bernreuther, C., Matschke, J., Barrera-Ocampo, A. A., Sepulveda-Falla, D., Leypoldt, F., Magnus, T., Haag, F., Bergmann, M., Brück, W., Vogelgesang, S. & Glatzel, M., 01.01.2014, In: NEURODEGENER DIS. 13, 1, p. 38-44 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuropsychological outcome after complicated Shiga toxin-producing Escherichia coli infection
Simova, O., Weineck, G., Schütze, T., Wegscheider, K., Panzer, U., Stahl, R. A. K., Gerloff, C. & Magnus, T., 01.01.2014, In: PLOS ONE. 9, 7, p. e103029Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells as early sensors of tissue damage and mediators of secondary neurodegeneration
Gelderblom, M., Arunachalam, P. & Magnus, T., 01.01.2014, In: FRONT CELL NEUROSCI. 8, p. 368Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke
Cheng, Y-L., Park, J-S., Manzanero, S., Choi, Y., Baik, S-H., Okun, E., Gelderblom, M., Fann, D. Y-W., Magnus, T., Launikonis, B. S., Mattson, M. P., Sobey, C. G., Jo, D-G. & Arumugam, T. V., 01.02.2014, In: NEUROBIOL DIS. 62, p. 286-95 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
Meyer, T., Franke, G., Polywka, S. K. A., Lütgehetmann, M., Gbadamosi, J., Magnus, T. & Aepfelbacher, M., 01.05.2014, In: J CLIN MICROBIOL. 52, 5, p. 1751-3 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cerebral Magnetic Resonance Imaging Findings in Adults with Haemolytic Uraemic Syndrome Following an Infection with Escherichia coli, Subtype O104:H4
Löbel, U., Eckert, B., Simova, O., Meier-Cillien, M., Kluge, S., Gerloff, C., Röther, J., Magnus, T. & Fiehler, J., 01.06.2014, In: CLIN NEURORADIOL. 24, 2, p. 111-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Upregulation of Shiga toxin Receptor CD77/Gb3 and Interleukin-1β Expression in Brain of EHEC Patients with Hemolytic Uremic Syndrome and Neurologic Symptoms
Hagel, C., Krasemann, S., Löffler, J., Püschel, K., Magnus, T. & Glatzel, M., 02.07.2014, In: BRAIN PATHOL. 25, 2, p. 146-156Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of CCR2 in inflammatory conditions of the central nervous system
Chu, H. X., Arumugam, T. V., Gelderblom, M., Magnus, T., Drummond, G. R. & Sobey, C. G., 01.09.2014, In: J CEREBR BLOOD F MET. 34, 9, p. 1425-9 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke
Gelderblom, M., Melzer, N., Schattling, B., Göb, E., Hicking, G., Arunachalam, P., Bittner, S., Ufer, F., Herrmann, A. M., Bernreuther, C., Glatzel, M., Gerloff, C., Kleinschnitz, C., Meuth, S. G., Friese, M. A. & Magnus, T., 01.11.2014, In: STROKE. 45, 11, p. 3395-3402 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Soluble plasma VE-cadherin concentrations are elevated in patients with STEC infection and haemolytic uraemic Syndrome: a case-control study
Doulgere, J., Otto, B., Nassour, M., Wolters-Eisfeld, G., Rohde, H., Magnus, T., Wagener, C. & Streichert, T., 01.01.2015, In: BMJ OPEN. 5, 3, p. e005659Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage
Cisneros-Mejorado, A., Gottlieb, M., Cavaliere, F., Magnus, T., Nolte, F., Scemes, E., Pérez-Samartín, A. & Matute, C., 05.2015, In: J CEREBR BLOOD F MET. 35, 5, p. 843-50 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Danger signals in stroke
Gelderblom, M., Sobey, C. G., Kleinschnitz, C. & Magnus, T., 11.2015, In: AGEING RES REV. 24, Pt A, Special Issue, p. 77-82 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primäre Vaskulitis des Zentralnervensystems
Schuster, S. & Magnus, T., 12.2015, In: Z RHEUMATOL. 74, 10, p. 854-62 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sichere Diagnose primärer ZNS-Vaskulitis nur mit bioptischem Nachweis
Schuster, S. & Magnus, T. U., 12.2015, In: Info Neurol Psych. 17, 12, p. 28-36Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Education
- 2016
Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography
Löbel, U., Forkert, N. D., Schmitt, P., Dohrmann, T. W., Schroeder, M., Magnus, T., Kluge, S., Weiler-Normann, C., Bi, X., Fiehler, J. & Sedlacik, J., 2016, In: PLOS ONE. 11, 11, p. e0164863Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frontal lobe dementia syndrome as a first manifestation of primary angiitis of the central nervous system (PACNS).
Bönstrup, M., Ott, K., Glatzel, M. & Magnus, T. U., 04.01.2016, In: CLIN NEUROL NEUROSUR. 141, p. 92-94Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative T2* mapping reveals early temporo-spatial dynamics in an ischemic stroke model
Gersing, A. S., Faymonville, A. M., Schwaiger, B. J., Leypoldt, F., Siemonsen, S., Zimmer, C., Magnus, T. & Fiehler, J., 01.02.2016, In: J NEUROSCI METH. 259, p. 83-89 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dendritic cells in brain diseases
Ludewig, P., Gallizioli, M., Urra, X., Behr, S., Brait, V. H., Gelderblom, M., Magnus, T. & Planas, A. M., 03.2016, In: BBA-MOL BASIS DIS. 1862, 3, p. 352-67 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis
Thom, V., Schmidt, S., Gelderblom, M., Hackbusch, R., Kolster, M., Schuster, S., Thomalla, G., Keminer, O., Pleß, O., Bernreuther, C., Glatzel, M., Wegscheider, K., Gerloff, C., Magnus, T. & Tolosa, E., 21.03.2016, In: NEUROL-NEUROIMMUNOL. 3, 2, p. e214Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation
Danquah, W., Meyer-Schwesinger, C., Rissiek, B., Pinto, C., Serracant-Prat, A., Amadi, M., Iacenda, D., Knop, J-H., Hammel, A., Bergmann, P., Schwarz, N., Assunção, J., Rotthier, W., Haag, F., Tolosa, E., Bannas, P., Boué-Grabot, E., Magnus, T., Laeremans, T., Stortelers, C. & Nolte, F., 23.11.2016, In: SCI TRANSL MED. 8, 366, p. 366ra162Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Antikörper-assoziierte autoimmune Enzephalopathien
Friese, M., Kastrup, O. & Magnus, T. U., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7., erweiterte und überarbeitete Auflage. Diener, H-C., Dieterich, M. & Gerloff, C. (eds.). 7 ed. Stuttgart: Kohlhammer, p. 770-780 11 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Correction: Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography
Löbel, U., Forkert, N. D., Schmitt, C. P., Dohrmann, T., Schroeder, M., Magnus, T., Kluge, S., Weiler-Normann, C., Bi, X., Fiehler, J. & Sedlacik, J., 2017, In: PLOS ONE. 12, 2, p. e0172450Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Paraneoplastische neurologische Symptome
Leypoldt, F., Magnus, T. U. & Voltz, R., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H-C., Dieterich, M. & Gerloff, C. (Hrsg.). 7 ed. Stuttgart: Kohlhammer, p. 979-989 11 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Radikuläre Syndrome
Magnus, T. U., Bischoff, C. & Diener, H., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H.-C., Dieterich, M. & Gerloff, C. (Hrsg.). 7 ed. Stuttgart: Kohlhammer, p. 1338-1351 13 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Riesenzellarteriitis und Polymyalgia rheumatica
Magnus, T. U. & Kleinschnitz, C., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H-C., Dieterich, M. & Gerloff, C. (Hrsg.) . 7 ed. Stuttgart : Kohlhammer, p. 463-469 8 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury
Thom, V., Arumugam, T. V., Magnus, T. & Gelderblom, M., 2017, In: FRONT IMMUNOL. 8, p. 875Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Vaskulitiden des ZNS
Dichgans, M., Gerloff, C. & Magnus, T. U., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H.-C., Dieterich, M. & Gerloff, C. (Hrsg.). 7 ed. Stuttgart: Kohlhammer, p. 438-462 24 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Silent Brain Infarctions and Leukoaraiosis in Patients With Retinal Ischemia: A Prospective Single-Center Observational Study
Golsari, A., Bittersohl, D., Cheng, B., Griem, P., Beck, C., Hassenstein, A., Nedelmann, M., Magnus, T., Fiehler, J., Gerloff, C. & Thomalla, G., 05.2017, In: STROKE. 48, 5, p. 1392-1396 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Edema is not a reliable diagnostic sign to exclude small brain metastases
Schneider, T., Kuhne, J. F., Bittrich, P., Schroeder, J., Magnus, T., Mohme, M., Grosser, M., Schoen, G., Fiehler, J. & Siemonsen, S., 11.05.2017, In: PLOS ONE. 12, 5, p. e0177217Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An atypical role for the myeloid receptor Mincle in central nervous system injury
Arumugam, T. V., Manzanero, S., Furtado, M., Biggins, P. J., Hsieh, Y-H., Gelderblom, M., MacDonald, K. P., Salimova, E., Li, Y-I., Korn, O., Dewar, D., Macrae, I. M., Ashman, R. B., Tang, S-C., Rosenthal, N. A., Ruitenberg, M. J., Magnus, T. & Wells, C. A., 06.2017, In: J CEREBR BLOOD F MET. 37, 6, p. 2098-2111Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia
Adesso, S., Magnus, T., Cuzzocrea, S., Campolo, M., Rissiek, B., Paciello, O., Autore, G., Pinto, A. & Marzocco, S., 12.06.2017, In: FRONT PHARMACOL. 8, p. 370Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke
Arunachalam, P., Ludewig, P., Melich, P., Arumugam, T. V., Gerloff, C., Prinz, I., Magnus, T. & Gelderblom, M., 07.2017, In: STROKE. 48, 7, p. 1957-1965 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypointense Vessels Detected by Susceptibility-Weighted Imaging Identifies Tissue at Risk of Infarction in Anterior Circulation Stroke
Cheng, B., Schröder, N., Forkert, N. D., Ludewig, P., Kemmling, A., Magnus, T., Fiehler, J., Gerloff, C. & Thomalla, G., 07.2017, In: J NEUROIMAGING. p. n/a-n/aResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Real-world experience of treatment decision-making in carotid stenosis in a neurovascular board
Rimmele, D. L., Larena-Avellaneda, A., Alegiani, A. C., Rosenkranz, M., Schmidt, N. O., Regelsberger, J., Hummel, F. C., Magnus, T., Debus, E. S., Fiehler, J., Gerloff, C. & Thomalla, G., 25.07.2017, In: NEUROLOGY. 89, 4, p. 399-407 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Subtypes of primary angiitis of the CNS identified by MRI patterns reflect the size of affected vessels
Schuster, S., Bachmann, H., Thom, V., Kaufmann-Buehler, A-K., Matschke, J., Siemonsen, S., Glatzel, M., Fiehler, J., Gerloff, C., Magnus, T. & Thomalla, G., 09.2017, In: J NEUROL NEUROSUR PS. 88, 9, p. 749-755 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
Klinisches Spektrum und Diagnosefindung bei rheumatoider Meningitis– Beschreibung von 5 Fällen
Braaß, H., Schuster, S., Lipp, M., Javidi, E., Schnoor, U., Iking-Konert, C., Matschke, J., Pötter-Nerger, M., Gerloff, C., Thomalla, G. & Magnus, T. U., 22.09.2017, Posterführung: Vaskulitiden und Neuroinfektiologie.Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Magnetic Particle Imaging for Real-Time Perfusion Imaging in Acute Stroke
Ludewig, P., Gdaniec, N., Sedlacik, J., Forkert, N. D., Szwargulski, P., Graeser, M., Adam, G., Kaul, M. G., Krishnan, K. M., Ferguson, R. M., Khandhar, A. P., Walczak, P., Fiehler, J., Thomalla, G., Gerloff, C., Knopp, T. & Magnus, T., 24.10.2017, In: ACS NANO. 11, 10, p. 10480-10488 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia
Rissiek, B., Menzel, S., Leutert, M., Cordes, M., Behr, S., Jank, L., Ludewig, P., Gelderblom, M., Rissiek, A., Adriouch, S., Haag, F., Hottiger, M. O., Koch-Nolte, F. & Magnus, T., 28.11.2017, In: SCI REP-UK. 7, 1, p. 16477Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Danger signals in stroke and their role on microglia activation after ischemia
Gülke, E., Gelderblom, M. & Magnus, T., 2018, In: THER ADV NEUROL DISO. 11, p. 1-14Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Monitoring the Sensitivity of T Cell Populations Towards NAD Released During Cell Preparation
Rissiek, B., Lukowiak, M., Haag, F., Magnus, T. & Koch-Nolte, F., 2018, ADP-RIBOSYLATION AND NAD+ UTILIZING ENZYMES: METHODS AND PROTOCOLS . Chang, P. (ed.). 1 ed. HUMANA PRESS INC, Vol. 1813. p. 317-326 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke
Gelderblom, M., Gallizioli, M., Ludewig, P., Thom, V., Arunachalam, P., Rissiek, B., Bernreuther, C., Glatzel, M., Korn, T., Arumugam, T. V., Sedlacik, J., Gerloff, C., Tolosa, E., Planas, A. M. & Magnus, T., 01.2018, In: STROKE. 49, 1, p. 155-164 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevalence of adult Pompe disease in patients with proximal myopathic syndrome and undiagnosed muscle biopsy
Golsari, A., Nasimzadah, A., Thomalla, G., Keller, S., Gerloff, C. & Magnus, T., 03.2018, In: NEUROMUSCULAR DISORD. 28, 3, p. 257-261 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells
Rissiek, B., Lukowiak, M., Raczkowski, F., Magnus, T., Mittrücker, H-W. & Koch-Nolte, F., 09.07.2018, In: FRONT IMMUNOL. 9, p. 1580Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis
Zabala, A., Vazquez-Villoldo, N., Rissiek, B., Gejo, J., Martin, A., Palomino, A., Perez-Samartín, A., Pulagam, K. R., Lukowiak, M., Capetillo-Zarate, E., Llop, J., Magnus, T., Koch-Nolte, F., Rassendren, F., Matute, C. & Domercq, M., 08.2018, In: EMBO MOL MED. 10, 8, p. UNSP e8743Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
Kaczmarek-Hajek, K., Zhang, J., Kopp, R., Grosche, A., Rissiek, B., Saul, A., Bruzzone, S., Engel, T., Jooss, T., Krautloher, A., Schuster, S., Magnus, T., Stadelmann, C., Sirko, S., Koch-Nolte, F., Eulenburg, V. & Nicke, A., 03.08.2018, In: ELIFE. 7, p. e36217Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rheumatoid meningitis A rare cause of aseptic meningitis with frequently stroke-like episodes
Schuster, S., Braaß, H., Iking-Konert, C., Schnoor, U., Matschke, J., Gerloff, C., Thomalla, G. & Magnus, T. U., 20.08.2018, In: NEUROL-CLIN PRACT. 8, 5, p. 451-455Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Molecular Communication of a Dying Neuron in Stroke
Puig, B., Brenna, S. & Magnus, T., 19.09.2018, In: INT J MOL SCI. 19, 9Research output: SCORING: Contribution to journal › SCORING: Review article › Research
IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke
Zhang, S. R., Piepke, M., Chu, H. X., Broughton, B. R., Shim, R., Wong, C. H., Lee, S., Evans, M. A., Vinh, A., Sakkal, S., Arumugam, T. V., Magnus, T., Huber, S., Gelderblom, M., Drummond, G. R., Sobey, C. G. & Kim, H. A., 20.09.2018, In: JCI INSIGHT. 3, 18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Generation and Function of Non-cell-bound CD73 in Inflammation
Schneider, E., Rissiek, A., Winzer, R., Puig, B., Rissiek, B., Haag, F., Mittrücker, H-W., Magnus, T. & Tolosa, E., 2019, In: FRONT IMMUNOL. 10, p. 1729Research output: SCORING: Contribution to journal › SCORING: Review article › Research