Prof. Dr. ID: 65683
Boris Fehse
Publications
5-azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity
Stübig, T., Badbaran, A., Luetkens, T., Hildebrandt, Y., Atanackovic, D., Binder, T. M. C., Fehse, B. & Kröger, N-M., 13.03.2014, In: MEDIAT INFLAMM. 2014, p. 418292Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance.
Bennour, E., Ferrand, C., Rémy-Martin, J-P., Certoux, J-M., Gorke, S., Qasim, W., Gaspar, H. B., Baumert, T., Duperrier, A., Deschamps, M., Fehse, B., Tiberghien, P. & Robinet, E., 2008, In: HUM GENE THER. 19, 7, p. 699-709 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Accurate In-Vivo Quantification of CD19 CAR-T Cells after Treatment with Axicabtagene Ciloleucel (Axi-Cel) and Tisagenlecleucel (Tisa-Cel) Using Digital PCR
Badbaran, A., Berger, C., Riecken, K., Kruchen, A., Geffken, M., Müller, I., Kröger, N., Ayuk, F. A. & Fehse, B., 20.07.2020, In: CANCERS. 12, 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells
Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1
Ellinger, B., Pohlmann, D., Woens, J., Jäkel, F. M., Reinshagen, J., Stocking, C., Prassolov, V. S., Fehse, B. & Riecken, K., 25.05.2020, In: VIRUSES-BASEL. 12, 5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.
Oyekunle, A. A., Kröger, N., Zabelina, T., Ayuketang Ayuk, F., Schieder, H., Renges, H., Fehse, N., Waschke, O., Fehse, B., Kabisch, H. & Zander, A. R., 2006, In: BONE MARROW TRANSPL. 37, 1, p. 45-50 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
Labenski, V., Suerth, J. D., Barczak, E., Heckl, D., Levy, C., Bernadin, O., Charpentier, E., Williams, D. A., Fehse, B., Verhoeyen, E. & Schambach, A., 26.04.2016, In: BIOMATERIALS. 97, p. 97-109 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis
Weber, K., Bartsch, U., Stocking, C. & Fehse, B., 2008, In: MOL THER. 16, 4, p. 698-706 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of progenitor cell mobilization and erythropoietin plasma levels in patients with acute myocardial infarction
Krause, K., Fehse, B., Jaquet, K., Lange, C., Kyriazis, K., Boczor, S., Zander, A. & Kuck, K-H., 01.01.2005, In: EXP CLIN CARDIOL. 10, 2, p. 104-7 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An antigen-specific chimeric autoantibody receptor (CAAR) NK cell strategy for the elimination of anti-PLA2R1 and anti-THSD7A antibody-secreting cells
Seifert, L., Riecken, K., Zahner, G., Hambach, J., Hagenstein, J., Dubberke, G., Huber, T. B., Koch-Nolte, F., Fehse, B. & Tomas, N. M., 04.2024, In: KIDNEY INT. 105, 4, p. 886-889 4 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses
Prokofjeva, M. M., Riecken, K., Spirin, P. V., Yanvarév, D. V., Düsedau, A., Ellinger, B., Fehse, B., Stocking, C. & Prassolov, V. S., 01.01.2013, In: AIDS research and therapy. 10, 1, p. 1Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel 'sort-suicide' fusion gene vector for T cell manipulation
Fehse, B., Kustikova, O. S., Li, Z., Wahlers, A., Bohn, W., Beyer, W. R., Chalmers, D., Tiberghien, P., Kühlcke, K., Zander, A. R. & Baum, C., 12.2002, In: GENE THER. 9, 23, p. 1633-1638 6 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells.
Rothweiler, F., Michaelis, M., Brauer, P., Otte, J., Riecken, K., Fehse, B., Doerr, H. W., Wiese, M., Kreuter, J., Al-Abed, Y., Nicoletti, F. & Cinatl, J., 2010, In: NEOPLASIA. 12, 12, p. 1023-1030 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antithymocyte globulin induces ex vivo and in vivo depletion of myeloid and plasmacytoid dendritic cells
Fang, L., Fehse, B., Engel, M., Zander, A. & Kröger, N., 15.02.2005, In: TRANSPLANTATION. 79, 3, p. 369-371 3 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Panse, J., Wolschke, C., Eiermann, T., Binder, T., Fehse, B., Erttmann, R., Kabisch, H., Bacher, U., Kröger, N. & Zander, A. R., 2008, In: EXP HEMATOL. 36, 8, p. 1047-1054 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anwendung des Genome Editing in der somatischen Gentherapie: Eine Einführung
Fehse, B. & Abramowski-Mock, U., 03.2021, Anwendung des Genome Editing in der somatischen Gentherapie. 1 ed. Wiesbaden: Springer, 48 p. (essentials).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma.
Kröger, N-M., Schwerdtfeger, R., Kiehl, M., Sayer, H. G., Renges, H-H., Zabelina, T., Fehse, B., Tögel, F., Wittkowsky, G., Kuse, R. & Zander, A., 2002, In: BLOOD. 100, 3, p. 755-760 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients
Schwarze, L. I., Sonntag, T., Wild, S., Schmitz, S., Uhde, A. & Fehse, B., 09.2021, In: GENE THER. 28, 9, p. 572-587 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Axicabtagene ciloleucel in vivo expansion and treatment outcome in aggressive B-cell lymphoma in a real-world setting
Ayuk, F. A., Berger, C., Badbaran, A., Zabelina, T., Sonntag, T., Riecken, K., Geffken, M., Wichmann, D., Frenzel, C., Thayssen, G., Zeschke, S., Kröger, N. & Fehse, B., 08.06.2021, In: BLOOD ADV. 5, 11, p. 2523-2527 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma
Ben Batalla, I., Schultze, A., Wroblewski, M., Erdmann, R., Heuser, M., Waizenegger, J. S., Riecken, K., Binder, M., Schewe, D., Sawall, S., Witzke, V., Cubas Cordova, M., Janning, M., Wellbrock, J., Fehse, B., Hagel, C., Krauter, J., Ganser, A., Lorens, J. B., Fiedler, W., Carmeliet, P., Pantel, K., Bokemeyer, C. & Loges, S., 03.10.2013, In: BLOOD. 122, 14, p. 2443-52 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.
Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling
Tintelnot, J., Metz, S., Trentmann, M., Oberle, A., von Wenserski, L., Schultheiß, C., Braig, F., Kriegs, M., Fehse, B., Riecken, K., Bokemeyer, C., Stein, A. & Binder, M., 2019, In: FRONT ONCOL. 9, p. 1559Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer Suicide Gene Therapy with TK.007
Hossain, J. A., Riecken, K., Miletic, H. & Fehse, B., 2019, In: Methods Mol Biol. 1895, p. 11-26 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.
Preuß, E., Muik, A., Riecken, K., Otte, J., von Laer, D. & Fehse, B., 2011, In: J MOL MED. 89, 11, p. 1113-1124 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients
Reinhard, H., Yousef, S., Luetkens, T., Fehse, B., Berdien, B., Kröger, N. & Atanackovic, D., 01.01.2014, In: BLOOD CANCER J. 4, p. e212Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CAR-HEMATOTOX: A model for CAR T-cell related hematological toxicity in relapsed/refractory large B-cell lymphoma
Rejeski, K., Perez Perez, A., Sesques, P., Hoster, E., Berger, C. S., Jentzsch, L., Mougiakakos, D., Frölich, L., Ackermann, J., Buecklein, V., Blumenberg, V., Schmidt, C., Jallades, L., Fehse, B., Faul, C., Karschnia, P., Weigert, O., Dreyling, M., Locke, F. L., von Bergwelt-Baildon, M., Mackensen, A., Bethge, W. A., Ayuk, F., Bachy, E., Salles, G. A., Jain, M. D. & Subklewe, M., 16.12.2021, In: BLOOD. 138, 24, p. 2499-2513 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CARs come to AID
Ayuk, F. & Fehse, B., 03.04.2024, In: MOL THER. 32, 4, p. 861-862 2 p.Research output: SCORING: Contribution to journal › Editorial › Research
CD133 marks a stem cell population that drives human Primary Myelofibrosis
Triviai, I., Stübig, T., Niebuhr, B., Hussein, K., Tsiftsoglou, A., Fehse, B., Stocking, C. & Kröger, N., 27.02.2015, In: HAEMATOLOGICA. 100, 6, p. 768-79Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD34 modulates the trafficking behavior of hematopoietic cells in vivo.
Lange, C., Li, Z., Fang, L., Baum, C. & Fehse, B., 2007, In: STEM CELLS DEV. 16, 2, p. 297-304 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation.
Oyekunle, A., Koehl, U., Schieder, H., Ayuketang Ayuk, F., Renges, H., Fehse, N., Zabelina, T., Fehse, B., Klingebiel, T., Sputtek, A., Zander, A. R. & Kröger, N., 2006, In: CYTOTHERAPY. 8, 4, p. 375-380 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD34 splice variant: an attractive marker for selection of gene-modified cells
Fehse, B., Richters, A., Putimtseva-Scharf, K., Klump, H., Li, Z., Ostertag, W., Zander, A. R. & Baum, C., 05.2000, In: MOL THER. 1, 5 Pt 1, p. 448-456 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD45-Directed CAR-T Cells with CD45 Knockout Efficiently Kill Myeloid Leukemia and Lymphoma Cells In Vitro Even after Extended Culture
Harfmann, M., Schröder, T., Głów, D., Jung, M., Uhde, A., Kröger, N., Horn, S., Riecken, K., Fehse, B. & Ayuk, F. A., 12.01.2024, In: CANCERS. 16, 2, 334.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation.
Atanackovic, D., Cao, Y., Luetkens, T., Panse, J., Faltz, C., Arfsten, J., Bartels, K., Wolschke, C., Eiermann, T., Zander, A. R., Fehse, B., Bokemeyer, C. & Kröger, N., 2008, In: HAEMATOLOGICA. 93, 3, p. 423-430 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).
Stocking, C., Grez, M., Fehse, B., von Laer, D., Itoh, K., Prassolov, V., Nowock, J., Kühlcke, K., Just, U., Schröder, T., Klump, H., Schiedlmeier, B., Grassman, E., Meyer, J., Li, Z., Schambach, A., Modlich, U., Kustikova, O., Galla, M., Jürgen, B., Zander, A. R. & Baum, C., 2010, In: HUM GENE THER. 21, 11, p. 1501-1503 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
Roh, V., Abramowski, P., Hiou-Feige, A., Cornils, K., Rivals, J-P., Zougman, A., Aranyossy, T., Thielecke, L., Truan, Z., Mermod, M., Monnier, Y., Prassolov, V., Glauche, I., Nowrouzi, A., Abdollahi, A., Fehse, B., Simon, C. & Tolstonog, G. V., 20.11.2018, In: CELL REP. 25, 8, p. 2208-2222.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cellular Therapy with Engineered T Cells, Efficacy and Side Effects
Bondanza, A., Bonini, C., Fehse, B. & Hudecek, M., 2019, The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies: The EBMT Handbook. Carreras, E., Dufour, C., Mohty, M. & Kröger, N. (eds.). 1 ed. Springer Nature Switzerland AG, p. 449-456 8 p.Research output: SCORING: Contribution to book/anthology › Chapter › Research
Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism
Braig, F., Kriegs, M., Voigtlaender, M., Habel, B., Grob, T., Biskup, K., Blanchard, V., Sack, M., Thalhammer, A., Ben Batalla, I., Braren, I., Laban, S., Danielczyk, A., Goletz, S., Jakubowicz, E., Märkl, B., Trepel, M., Knecht, R., Riecken, K., Fehse, B., Loges, S., Bokemeyer, C. & Binder, M., 01.03.2017, In: CANCER RES. 77, 5, p. 1188-1199 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chancen und Risiken der CAR-T-Zell-Therapie
Ayuk, F. A., Fehse, B., Berger, S. C., Riecken, K. & Kroger, N., 10.2019, In: Hamb Ärztebl. 73, 10, p. 30-32Research output: SCORING: Contribution to journal › SCORING: Review article › Education
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
Baum, C., von Kalle, C., Staal, F. J. T., Li, Z., Fehse, B., Schmidt, M., Weerkamp, F., Karlsson, S., Wagemaker, G. & Williams, D. A., 01.2004, In: MOL THER. 9, 1, p. 5-13 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
Grochowska, K. M., Sperveslage, M., Raman, R., Failla, A. V., Głów, D., Schulze, C., Laprell, L., Fehse, B. & Kreutz, M. R., 29.08.2023, In: CELL REP. 42, 8, p. 112998Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chimeric autoantibody receptor cell therapy for the treatment of membranous nephropathy: The authors reply
Fehse, B. & Tomas, N. M., 06.2024, In: KIDNEY INT. 105, 6, p. 1320-1321 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia.
Wiedemann, B., Klyuchnikov, E., Kröger, N., Zabelina, T., Stahl, T., Zeschke, S., Badbaran, A., Ayuketang Ayuk, F., Alchalby, H., Wolschke, C., Bokemeyer, C., Fehse, B., Zander, A. R. & Bacher, U., 2010, In: EXP HEMATOL. 38, 12, p. 1261-1271 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical application of a retroviral gene transfer protocol based on centrifugation-mediated vector preloading.
Fehse, B., 2008, In: HUM GENE THER. 19, 6, p. 655-658 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion
Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In: MOL CANCER. 16, 1, p. 120Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking
Kustikova, O., Fehse, B., Modlich, U., Yang, M., Düllmann, J., Kamino, K., von Neuhoff, N., Schlegelberger, B., Li, Z. & Baum, C., 20.05.2005, In: SCIENCE. 308, 5725, p. 1171-4 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks
Brenière-Letuffe, D., Domke-Shibamiya, A., Hansen, A., Eschenhagen, T., Fehse, B., Riecken, K. & Stenzig, J., 18.06.2018, In: STEM CELL RES THER. 9, 1, p. 165Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal Evolution after Allogeneic Hematopoietic Stem Cell Transplantation
Christopeit, M., Badbaran, A., Alawi, M., Flach, J., Fehse, B. & Kröger, N., 07.2020, In: BIOL BLOOD MARROW TR. 26, 7, p. e167-e170Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity
Abramowski, P., Kraus, O., Rohn, S., Riecken, K., Fehse, B. & Schlüter, H., 03.07.2015, In: CANCER GENOM PROTEOM. 12, 4, p. 179-187 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model
Moustafa, M., Dähling, K-K., Günther, A., Riebandt, L., Smit, D. J., Riecken, K., Schröder, C., Zhuang, R., Krech, T., Kriegs, M., Fehse, B., Izbicki, J., Fischer, L., Nashan, B., Li, J. & Jücker, M., 08.04.2022, In: CANCERS. 14, 8, 1882.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or a γ-retroviral LTR vector
Cornils, K., Bartholomae, C. C., Thielecke, L., Lange, C., Arens, A., Glauche, I., Mock, U., Riecken, K., Gerdes, S., von Kalle, C., Schmidt, M., Roeder, I. & Fehse, B., 01.01.2013, In: EXP HEMATOL. 41, 1, p. 28-38.e3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients
Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of two doses of antithymocyte globulin in patients undergoing matched unrelated donor allogeneic stem cell transplantation.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Wolschke, C., Fehse, B., Bacher, U., Erttmann, R., Kröger, N. & Zander, A. R., 2008, In: BIOL BLOOD MARROW TR. 14, 8, p. 913-919 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Complement-dependent and complement-independent cytotoxicity of polyclonal antithymocyte globulins in chronic lymphocytic leukemia.
Ayuketang Ayuk, F., Atassi, N., Schuch, G., Mina, S., Fang, L., Bokemeyer, C., Fehse, B., Zander, A. R. & Kröger, N., 2008, In: LEUKEMIA RES. 32, 8, p. 1200-1206 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study.
Lippert, E., Girodon, F., Hammond, E., Jelinek, J., Reading, N. S., Fehse, B., Hanlon, K., Hermans, M., Richard, C., Swierczek, S., Ugo, V., Carillo, S., Harrivel, V., Marzac, C., Pietra, D., Sobas, M., Mounier, M., Migeon, M., Ellard, S., Kröger, N., Herrmann, R., Prchal, J. T., Skoda, R. C. & Hermouet, S., 2009, In: HAEMATOLOGICA. 94, 1, p. 38-45 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China
Büning, H., Griesenbach, U., Fehse, B., Ylä-Herttuala, S., Anagnou, N. P., van Beusechem, V., Raya, A. & Verhoeyen, E., 12.2018, In: HUM GENE THER. 29, 12, p. 1337–1338 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Correction: Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
Schwarze, L. I., Głów, D., Sonntag, T., Uhde, A. & Fehse, B., 02.2023, In: GENE THER. 30, 1-2, p. 187Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Correction: Role of growth arrest-specific gene 6-mer axis in multiple myeloma
Waizenegger, J. S., Ben-Batalla, I., Weinhold, N., Meissner, T., Wroblewski, M., Janning, M., Riecken, K., Binder, M., Atanackovic, D., Taipaleenmaeki, H., Schewe, D., Sawall, S., Gensch, V., Cubas-Cordova, M., Seckinger, A., Atanackovic, D., Hesse, E., Kröger, N., Fehse, B., Hose, D., Klein, B., Raab, M. S., Pantel, K., Bokemeyer, C. & Loges, S., 09.2020, In: LEUKEMIA. 34, 9, p. 2542Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
CRISPR-to-Kill (C2K)–Employing the Bacterial Immune System to Kill Cancer Cells
Glow, D., Maire, C., Schwarze, L-I., Lamszus, K. & Fehse, B., 15.12.2021, In: CANCERS. 13, 24, 6306.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs
Ben-Batalla, I., Cubas-Cordova, M., Udonta, F., Wroblewski, M., Waizenegger, J. S., Janning, M., Sawall, S., Gensch, V., Zhao, L., Martinez-Zubiaurre, I., Riecken, K., Fehse, B., Pantel, K., Bokemeyer, C. & Loges, S., 20.03.2015, In: ONCOTARGET. 6, 8, p. 6341-58 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep Characterization and Comparison of Different Retrovirus-like Particles Preloaded with CRISPR/Cas9 RNPs
Wichmann, M., Maire, C. L., Nuppenau, N., Habiballa, M., Uhde, A., Kolbe, K., Schröder, T., Lamszus, K., Fehse, B. & Głów, D., 13.07.2023, In: INT J MOL SCI. 24, 14, p. 11399Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL
Schieferdecker, A., Voigt, M., Riecken, K., Braig, F., Schinke, T., Loges, S., Bokemeyer, C., Fehse, B. & Binder, M., 30.08.2014, In: ONCOTARGET. 5, 16, p. 6647-53 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development of CAR-T cell therapies for multiple myeloma
Gagelmann, N., Riecken, K., Wolschke, C., Berger, C., Ayuk, F. A., Fehse, B. & Kröger, N., 09.2020, In: LEUKEMIA. 34, 9, p. 2317-2332 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Differences in proportion and dynamics of recipient hematopoiesis following hematopoietic cell transplantation in CML and IMF.
Siebolts, U., Thiele, J., Zander, T., Ditschkowski, M., Beelen, D. W., Kröger, N., Fehse, B. & Wickenhauser, C., 2008, In: ONCOL REP. 19, 1, p. 287-292 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital-droplet PCR assays for IDH, DNMT3A and driver mutations to monitor after allogeneic stem cell transplantation minimal residual disease of myelofibrosis
Mannina, D., Badbaran, A., Wolschke, C., Klyuchnikov, E., Christopeit, M., Fehse, B. & Kröger, N., 03.2022, In: BONE MARROW TRANSPL. 57, 3, p. 510-512 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Digital-PCR assay for screening and quantitative monitoring of calreticulin (CALR) type-2 positive patients with myelofibrosis following allogeneic stem cell transplantation
Badbaran, A., Fehse, B., Christopeit, M., Aranyossy, T., Ayuketang, F. A., Wolschke, C. & Kröger, N., 06.2016, In: BONE MARROW TRANSPL. 51, 6, p. 872-3Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel
Fehse, B., Badbaran, A., Berger, C., Sonntag, T., Riecken, K., Geffken, M., Kröger, N. & Ayuk, F. A., 13.03.2020, In: MOL THER-METH CLIN D. 16, p. 172-178 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR Panel for Sensitive Hematopoietic Chimerism Quantification after Allogeneic Stem Cell Transplantation
Stahl, T., Rothe, C., Böhme, M. U., Kohl, A., Kröger, N. & Fehse, B., 2016, In: INT J MOL SCI. 17, 9, p. E1515Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases
Mock, U., Hauber, I. & Fehse, B., 03.2016, In: NAT PROTOC. 11, 3, p. 598-615 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR to assess hematopoietic chimerism after allogeneic stem cell transplantation
Stahl, T., Böhme, M., Kröger, N. & Fehse, B., 18.03.2015, In: EXP HEMATOL. 43, 6, p. 462-468Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues
Badbaran, A., Mailer, R. K., Dahlke, C., Woens, J., Fathi, A., Mellinghoff, S. C., Renné, T., Addo, M. M., Riecken, K. & Fehse, B., 10.12.2021, In: MOL THER-METH CLIN D. 23, p. 418-423 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diva-Fit: A step-by-step manual for generating high-resolution graphs and histogram overlays of flow cytometry data obtained with FACSDiva software
Riecken, K. & Fehse, B., 2009, In: CTT-Cell Ther Transpl. 1, 4, p. 1-4 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dominant selection of hematopoietic progenitor cells with retroviral MDR1 co-expression vectors
Hildinger, M., Fehse, B., Hegewisch-Becker, S., John, J., Rafferty, J. R., Ostertag, W. & Baum, C., 01.01.1998, In: HUM GENE THER. 9, 1, p. 33-42 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients
Kruchen, A., Stahl, T., Gieseke, F., Binder, T. M. C., Özcan, Z., Meisel, R., Kreyenberg, H., Bader, P., Gruhn, B., Greil, J., Pfeiffer, M., Döring, M., Handgretinger, R., Fehse, B. & Müller, I., 22.06.2015, In: BONE MARROW TRANSPL. 50, 10, p. 1367-1370Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Donor Lymphocyte Infusion and Molecular Monitoring for Relapsed Myelofibrosis After Hematopoietic Cell Transplantation
Gagelmann, N., Wolschke, C., Badbaran, A., Janson, D., Berger, C., Klyuchnikov, E., Ayuk, F., Fehse, B. & Kröger, N., 07.2023, In: HEMASPHERE. 7, 7, p. e921Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population
Kustikova, O. S., Wahlers, A., Kuhlcke, K., Stahle, B., Zander, A. R., Baum, C. & Fehse, B., 01.12.2003, In: BLOOD. 102, 12, p. 3934-7 4 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers
Timin, A. S., Muslimov, A. R., Lepik, K. V., Epifanovskaya, O. S., Shakirova, A. I., Mock, U., Riecken, K., Okilova, M. V., Sergeev, V. S., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 01.2018, In: NANOMED-NANOTECHNOL. 14, 1, p. 97-108 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient lentiviral transduction and transgene expression in primary human B cells.
Mock, U., Thiele, R., Uhde, A., Fehse, B. & Horn, S., 2012, In: HUM GENE THER METHOD. 23, 6, p. 408-415 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient Pseudotyping of Different Retroviral Vectors Using a Novel, Codon-Optimized Gene for Chimeric GALV Envelope
Mirow, M., Schwarze, L. I., Fehse, B. & Riecken, K., 27.07.2021, In: VIRUSES-BASEL. 13, 8, 1471.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Einleitung: Gentechnologien in Deutschland im Fokus der IAG Gentechnologiebericht
Fehse, B., Marx-Stölting, L., Schickl, H. & Khachatryan, A., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 81-86 6 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 44).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Einleitung: Gen- und Zelltherapie – „zwei Seiten zweier Medaillen“
Fehse, B., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 11-21 11 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Endogenous retrovirus induces leukemia in a xenograft mouse model for primary myelofibrosis
Triviai, I., Ziegler, M., Bergholz, U., Oler, A. J., Stübig, T., Prassolov, V., Fehse, B., Kozak, C. A., Kröger, N-M. & Stocking, C., 10.06.2014, In: P NATL ACAD SCI USA. 111, 23, p. 8595 - 8600Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
Braig, F., März, M., Schieferdecker, A., Schulte, A., Voigt, M., Stein, A., Grob, T., Alawi, M., Indenbirken, D., Kriegs, M., Engel, E., Vanhoefer, U., Grundhoff, A., Loges, S., Riecken, K., Fehse, B., Bokemeyer, C. & Binder, M., 20.05.2015, In: ONCOTARGET. 6, 14, p. 12035-47 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Erratum for "Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors"
Trepel, M., Körbelin, J., Spies, E., Heckmann, M. B., Hunger, A., Fehse, B., Katus, H. A., Kleinschmidt, J. A., Müller, O. J. & Michelfelder, S., 10.2015, In: GENE THER. 22, 10, p. 840-847Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Excellent proliferation and persistence of allogeneic donor-derived 41-BB based CAR-T cells despite immunosuppression with cyclosporine A
Ayuk, F., Fehse, B., Janson, D., Berger, C., Riecken, K. & Kröger, N., 06.2020, In: HAEMATOLOGICA. 105, 6, p. 322-324 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Excision of specific DNA-sequences from integrated retroviral vectors via site-specific recombination
Bergemann, J., Kühlcke, K., Fehse, B., Ratz, I., Ostertag, W. & Lother, H., 11.11.1995, In: NUCLEIC ACIDS RES. 23, 21, p. 4451-6 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fucoidans as potential inhibitors of HIV-1
Prokofjeva, M. M., Imbs, T. I., Shevchenko, N. M., Spirin, P. V., Horn, S., Fehse, B., Zvyagintseva, T. N. & Prassolov, V. S., 01.01.2013, In: MAR DRUGS. 11, 8, p. 3000-14 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene and Cell Therapy in Germany
von Kalle, C., Fehse, B. & Büning, H., 10.2017, In: HUM GENE THER. 28, 10, p. 781Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation
Staffeldt, L., Mattert, G., Riecken, K., Rövenstrunk, G., Volkmar, A., Heumann, A., Moustafa, M., Jücker, M., Fehse, B., Schumacher, U., Lüth, S. & Kah, J., 30.12.2023, In: CELLS-BASEL. 13, 1, 82.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene Therapy "Made in Germany": A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy
Büning, H., Fehse, B., Ivics, Z., Kochanek, S., Koehl, U., Kupatt, C., Mussolino, C., Nettelbeck, D. M., Schambach, A., Uckert, W., Wagner, E. & Cathomen, T., 10.2021, In: HUM GENE THER. 32, 19-20, p. 987-996 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene therapy strategies: can we eradicate HIV?
van Lunzen, J., Fehse, B. & Hauber, J., 2011, In: CURR HIV-AIDS REP. 8, 2, p. 78-84 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetically modified neural stem cells for a local and sustained delivery of neuroprotective factors to the dystrophic mouse retina
Jung, G., Sun, J., Petrowitz, B., Riecken, K., Kruszewski, K., Jankowiak, W., Kunst, F., Skevas, C., Richard, G., Fehse, B. & Bartsch, U., 01.12.2013, In: STEM CELL TRANSL MED. 2, 12, p. 1001-10 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic barcodes facilitate competitive clonal analyses in vivo
Aranyossy, T., Thielecke, L., Glauche, I., Fehse, B. & Cornils, K., 10.2017, In: HUM GENE THER. 28, 10, p. 926-937Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic Modifications – Possibilities and Limits of Gene Therapy
Fehse, B., 2011, Human Nature and Self Design. mentis Verlag Paderborn, p. 113-136 24 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Genetische Manipulation: klinische Anwendung.
Fehse, B. & Cornils, K., 2015, Hämatopoetische Stammzellen: Grundlagen und klinische Einsatzgebiete. Herr, W., Theobald, M., Ehninger, G., Einsele, H. & Meyer, R. G. (eds.). 1 ed. Köln: Deutscher Ärzte-Verlag, p. 21-24 4 p. 6Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.
Metzner, A., Horstmann, M., Fehse, B., Ortmeyer, G., Niemeyer, C. M., Stocking, C., Mayr, G. W. & Jücker, M., 2007, In: GENE THER. 14, 8, p. 699-703 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomeditierung durch CRISPR und Co
Fehse, B., 2018, Stammzellforschung: Aktuelle wissenschaftliche und gesellschaftliche Entwicklungen. Zenke, M., Marx-Stölting, L. & Schickl, H. (eds.). 1 ed. Baden-Baden: Nomos, p. 97-114 18 p. 4. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 39).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Genome-Editing – Gentherapie 2.0 oder nur eine Wunschvorstellung?
Fehse, B., Grünewald, J. & Petri, K., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 103-120 18 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Genome-Editing und Einzelzellanalyse: Neue Methoden und ihre Implikationen für Forschung, Anwendung und Gesellschaft
Fehse, B., Walter, J., Reich, J., Marx-Stölting, L., Pichl, A. & Schickl, H., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 219-250 32 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 44).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Gentherapie
Köchy, K., Domasch, S. & Fehse, B., 2014, Handbuch Ethik & Recht der Forschung am Menschen. Lenk, C., Duttge, G. & Fangerau, H. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 427 - 432 5 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research
Gentherapie in Deutschland. Eine Einführung
Domasch, S. & Fehse, B., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 31-40 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Gentherapie - zurück in die Zukunft?
Fehse, B., 06.2015, In: BIOspektrum. 15, 4, p. 448Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer
Gezielter CCR5-Knockout in primären T-Lymphozyten zur Verhinderung der HIV-Infektion
Mock, U. & Fehse, B., 09.2015, Connexi. The Paideia Group, Vol. 6-2015. p. 14-16 3 p.Research output: SCORING: Contribution to book/anthology › Conference contribution - Article for conference › Research › peer-review
Glioma escape signature and clonal development under immune pressure
Maire, C. L., Mohme, M., Bockmayr, M., Fita, K. D., Riecken, K., Börnigen, D., Alawi, M., Failla, A. V., Kolbe, K., Zapf, S., Holz, M., Neumann, K., Dührsen, L., Lange, T., Fehse, B., Westphal, M. & Lamszus, K., 01.10.2020, In: J CLIN INVEST. 130, 10, p. 5257-5271 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hämatopoetische Stammzelltransplantation: seit Jahrzehnten etablierte Zelltherapie
Kolb, H-J. & Fehse, B., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg, p. 161-181 21 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Handlungsempfehlungen zur somatischen Gentherapie, Keimbahninterventionen und Zelltherapie
Fehse, B., Walter, J., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Müller-Terpitz, R., Mundlos, S., Jens, R., Schicktanz, S., Winkler, E. C. & Zenke, M., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 1-10 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Hepatic lineages isolated from developing rat liver show different ways of maturation.
Fiegel, H. C., Kluth, J., Lioznov, M., Holzhüter, S., Fehse, B., Zander, A. & Kluth, D., 2003, In: BIOCHEM BIOPH RES CO. 305, 1, p. 46-53 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo
Giersch, K., Bhadra, O. D., Volz, T., Allweiss, L., Riecken, K., Fehse, B., Lohse, A. W., Petersen, J., Sureau, C., Urban, S., Dandri, M. & Lütgehetmann, M., 01.2019, In: GUT. 68, 1, p. 150-157 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High bone turnover in mice carrying a pathogenic Notch2-mutation causing Hajdu-Cheney syndrome
Vollersen, N., Hermans-Borgmeyer, I., Cornils, K., Fehse, B., Rolvien, T., Triviai, I., Jeschke, A., Oheim, R., Amling, M., Schinke, T. & Yorgan, T. A., 01.2018, In: J BONE MINER RES. 33, 1, p. 70-83 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-efficiency retroviral vector-mediated gene transfer into human T lymphocytes
Li, Z. X., Schade, U. M., Fehse, B., Stockschläder, M., Uhde, A., Koch, S., Goller, B., Rüger, R., Fehse, N. & Zander, A. R., 1998, In: ADV EXP MED BIOL. 451, p. 375-378 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Highly-efficient gene transfer with retroviral vectors into human T lymphocytes on fibronectin
Fehse, B., Schade, U. M., Li, Z., Uhde, A., Koch, S., Goller, B., Rüger, R., Fehse, N., Stockschläder, M. & Zander, A. R., 01.07.1998, In: BRIT J HAEMATOL. 102, 2, p. 566-74 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Highly efficient lentiviral transduction of phenotypically and genotypically characterized endothelial progenitor cells from adult peripheral blood.
Stockschlaeder, M., Shardakova, O., Riecken, K., Stoldt, V. R., Fehse, B., Giers, G. & Scharf, R. E., 2010, In: BLOOD COAGUL FIBRIN. 21, 5, p. 464-473 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1
Kuzikov, M., Woens, J., Zaliani, A., Hambach, J., Eden, T., Fehse, B., Ellinger, B. & Riecken, K., 07.2022, In: BIOMED PHARMACOTHER. 151, 113104.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells
Zecher, B. F., Ellinghaus, D., Schloer, S., Niehrs, A., Padoan, B., Baumdick, M. E., Yuki, Y., Martin, M. P., Glow, D., Schröder-Schwarz, J., Niersch, J., Brias, S., Müller, L. M., Habermann, R., Kretschmer, P., Früh, T., Dänekas, J., Wehmeyer, M. H., Poch, T., Sebode, M., International PSC Study Group (IPSCSG), Ellinghaus, E., Degenhardt, F., Körner, C., Hoelzemer, A., Fehse, B., Oldhafer, K. J., Schumacher, U., Sauter, G., Carrington, M., Franke, A., Bunders, M. J., Schramm, C. & Altfeld, M., 05.01.2024, In: GUT. 73, 2, p. 325-337 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
How to package and SEND mRNA: a novel "humanized" vector system based on endogenous retroviruses
Riecken, K., Glow, D. & Fehse, B., 05.11.2021, In: SIGNAL TRANSDUCT TAR. 6, 1, 384.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Human mesenchymal stem cells are not of donor origin in patients with severe aplastic anemia who underwent sex-mismatched allogeneic bone marrow transplant
Stute, N., Fehse, B., Schröder, J., Arps, S., Adamietz, P., Held, K. R. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 977-984 8 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction
Shiri, A. M., Zhang, T., Bedke, T., Zazara, D. E., Zhao, L., Lücke, J., Sabihi, M., Fazio, A., Zhang, S., Tauriello, D. V. F., Batlle, E., Steglich, B., Kempski, J., Agalioti, T., Nawrocki, M., Xu, Y., Riecken, K., Liebold, I., Brockmann, L., Konczalla, L., Bosurgi, L., Mercanoglu, B., Seeger, P., Küsters, N., Lykoudis, P. M., Heumann, A., Arck, P. C., Fehse, B., Busch, P., Grotelüschen, R., Mann, O., Izbicki, J. R., Hackert, T., Flavell, R. A., Gagliani, N., Giannou, A. D. & Huber, S., 04.2024, In: J HEPATOL. 80, 4, p. 634-644 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis
Riedel, J-H., Becker, M., Kopp, K., Düster, M., Brix, S. R., Meyer-Schwesinger, C., Kluth, L. A., Gnirck, A-C., Attar, M., Krohn, S., Fehse, B., Stahl, R. A. K., Panzer, U. & Turner, J-E., 07.2017, In: J AM SOC NEPHROL. 28, 7, p. 2068-2080Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Ricklefs, F. L., Maire, C. L., Reimer, R., Dührsen, L., Kolbe, K., Holz, M., Schneider, E., Rissiek, A., Babayan, A., Hille, C., Pantel, K., Krasemann, S., Glatzel, M., Heiland, D. H., Flitsch, J., Martens, T., Schmidt, N. O., Peine, S., Breakefield, X. O., Lawler, S., Chiocca, E. A., Fehse, B., Giebel, B., Görgens, A., Westphal, M. & Lamszus, K., 2019, In: J EXTRACELL VESICLES. 8, 1, p. 1588555Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune Monitoring
Berger, S. C., Fehse, B. & Rubio, M-T., 2022, The EBMT/EHA CAR-T Cell Handbook. Kröger, N., Gribben, J., Chabannon, C., Yakoub-Agha, I. & Einsele, H. (eds.). 1 ed. Cham: Springer International Publishing, p. 177-182 6 p.Research output: SCORING: Contribution to book/anthology › Chapter › Research
Impact of a new generation of gene transfer markers on gene therapy
Fehse, B., Li, Z., Schade, U. M., Uhde, A. & Zander, A. R., 04.1998, In: GENE THER. 5, 4, p. 429-430 2 p.Research output: SCORING: Contribution to journal › Editorial › Research
Impact of high-risk cytogenetics and achievement of molecular remission on long-term freedom from disease after autologous-allogeneic tandem transplantation in patients with multiple myeloma.
Kröger, N-M., Badbaran, A., Zabelina, T., Ayuketang, F. A., Wolschke, C., Alchalby, H., Klyuchnikov, E., Atanackovic, D., Schilling, G., Hansen, T., Schwarz, S., Heinzelmann, M., Zeschke, S., Bacher, U., Stübig, T., Fehse, B. & Zander, A. R., 2013, In: BIOL BLOOD MARROW TR. 19, 3, p. 398-404 7 p., 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis.
Alchalby, H., Badbaran, A., Zabelina, T., Kobbe, G., Hahn, J., Wolff, D., Bornhäuser, M., Christian, T., Baurmann, H., Bethge, W., Hildebrandt, Y., Bacher, U., Fehse, B., Zander, A. R. & Kröger, N., 2010, In: BLOOD. 116, 18, p. 3572-3581 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation
Kröger, N., Panagiota, V., Badbaran, A., Zabelina, T., Triviai, I., Araujo Cruz, M. M., Shahswar, R., Ayuketang, F. A., Gehlhaar, M., Wolschke, C., Bollin, R., Walter, C., Dugas, M., Wiehlmann, L., Lehmann, U., Koenecke, C., Chaturvedi, A., Alchalby, H., Stadler, M., Eder, M., Christopeit, M., Göhring, G., Koenigsmann, M., Schlegelberger, B., Kreipe, H-H., Ganser, A., Stocking, C., Fehse, B., Thol, F. & Heuser, M., 07.2017, In: BIOL BLOOD MARROW TR. 23, 7, p. 1095-1101Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of molecular residual disease post allografting in myelofibrosis patients
Wolschke, C., Badbaran, A., Zabelina, T., Christopeit, M., Ayuketang, F. A., Triviai, I., Zander, A., Alchalby, H., Bacher, U., Fehse, B. & Kröger, N-M., 11.2017, In: BONE MARROW TRANSPL. 52, 11, p. 1526-1529Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I
Kühn, S. C., Koehne, T., Cornils, K., Markmann, S., Riedel, C., Pestka, J. M., Schweizer, M., Baldauf, C., Yorgan, T. A., Krause, M., Keller, J., Neven, M., Breyer, S., Stücker, R., Muschol, N., Busse, B., Braulke, T., Fehse, B., Amling, M. & Schinke, T., 15.12.2015, In: HUM MOL GENET. 24, 24, p. 7075-7086Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Improving the ex vivo retroviral-mediated suicide-gene transfer process in T lymphocytes to preserve immune function
Robinet, E., Fehse, B., Ebeling, S., Sauce, D., Ferrand, C. & Tiberghien, P., 2005, In: CYTOTHERAPY. 7, 2, p. 150-7 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation.
Fehse, N., Fehse, B., Kröger, N-M., Zabelina, T., Freiberger, P., Krüger, W., Kabisch, H., Erttmann, R. & Zander, A., 2003, In: J HEMATOTH STEM CELL. 12, 2, p. 237-242 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child's Leukemic Blasts
Martin, L-M., Kruchen, A., Fehse, B. & Müller, I., 04.03.2022, In: BIOMEDICINES. 10, 3, 603.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of mannose-binding lectin genotypes and serostatus in allo-SCT: analysis of 131 recipients and donors.
Neth, O. W., Bacher, U., Das, P., Zabelina, T., Kabisch, H., Kroeger, N., Ayuketang, F. A., Lioznov, M., Waschke, O., Fehse, B., Thiébaut, R., Haston, R. M., Klein, N. & Zander, A. R., 01.01.2010, In: BONE MARROW TRANSPL. 45, 1, p. 13-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influenza virus-specific TCR-transduced T cells as a model for adoptive immunotherapy
Berdien, B., Reinhard, H., Meyer, S., Spöck, S., Kröger, N-M., Atanackovic, D. & Fehse, B., 01.06.2013, In: HUM VACC IMMUNOTHER. 9, 6, p. 1205-16 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insertional mutagenesis and clonal dominance: biological and statistical considerations.
Fehse, B. & Roeder, I., 2008, In: GENE THER. 15, 2, p. 143-153 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene.
Li, Z., Kustikova, O. S., Kamino, K., Neumann, T., Rhein, M., Grassman, E., Fehse, B. & Baum, C., 2007, In: ANN NY ACAD SCI. 1106, p. 95-113Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia
Greinacher, A., Selleng, K., Palankar, R., Wesche, J., Handtke, S., Wolff, M., Aurich, K., Lalk, M., Methling, K., Volker, U., Hentschker, C., Michalik, S., Steil, L., Reder, A., Schönborn, L., Beer, M., Franzke, K., Büttner, A., Fehse, B., Stavrou, E. X., Rangaswamy, C., Mailer, R. K., Englert, H., Frye, M., Thiele, T., Kochanek, S., Krutzke, L., Siegerist, F., Endlich, N., Warkentin, T. E. & Renné, T., 02.12.2021, In: BLOOD. 138, 22, p. 2256-2268 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice
Dulz, S., Bassal, M., Flachsbarth, K., Riecken, K., Fehse, B., Schlichting, S., Bartsch, S. & Bartsch, U., 11.09.2020, In: CELLS-BASEL. 9, 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Investigation of the Mesenchymal Stem Cell Compartment by Means of a Lentiviral Barcode Library
Bigildeev, A. E., Cornils, K., Aranyossy, T., Sats, N. V., Petinati, N. A., Shipounova, I. N., Surin, V. L., Pshenichnikova, O. S., Riecken, K., Fehse, B. & Drize, N. I., 04.2016, In: BIOCHEMISTRY-MOSCOW+. 81, 4, p. 373-81 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets
Carlet, M., Völse, K., Vergalli, J., Becker, M., Herold, T., Arner, A., Senft, D., Jurinovic, V., Liu, W-H., Gao, Y., Dill, V., Fehse, B., Baldus, C. D., Bastian, L., Lenk, L., Schewe, D. M., Bagnoli, J. W., Vick, B., Schmid, J. P., Wilhelm, A., Marschalek, R., Jost, P. J., Miething, C., Riecken, K., Schmidt-Supprian, M., Binder, V. & Jeremias, I., 27.09.2021, In: NAT COMMUN. 12, 1, p. 5655Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In-vivo RGB marking and multicolour single-cell tracking in the adult brain
Gomez-Nicola, D., Riecken, K., Fehse, B. & Perry, V. H., 22.12.2014, In: SCI REP-UK. 4, p. 7520Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Is multiple sclerosis progression associated with the HLA-DR15 haplotype?
Stürner, K. H., Siembab, I., Schön, G., Stellmann, J-P., Heidari, N., Fehse, B., Heesen, C., Eiermann, T. H., Martin, R. & Binder, T. M., 17.12.2019, In: Mult Scler J-Exp Transl Clin. 5, 4, p. 2055217319894615Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation.
Kröger, N., Alchalby, H., Klyuchnikov, E., Badbaran, A., Hildebrandt, Y., Ayuketang Ayuk, F., Bacher, U., Bock, O., Kvasnicka, M., Fehse, B. & Zander, A. R., 2009, In: BLOOD. 113, 8, p. 1866-1868 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Kinetics of plasma-cell chimerism after allogeneic stem cell transplantation by highly sensitive real-time PCR based on sequence polymorphism and its value to quantify minimal residual disease in patients with multiple myeloma.
Kröger, N., Zagrivnaja, M., Schwartz, S., Badbaran, A., Zabelina, T., Lioznov, M., Ayuketang Ayuk, F., Zander, A. R. & Fehse, B., 2006, In: EXP HEMATOL. 34, 5, p. 688-694 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
LATE-a novel sensitive cell-based assay for the study of CRISPR/Cas9-related long-term adverse treatment effects
Głów, D., Meyer, S., García Roldán, I., Akingunsade, L. M., Riecken, K. & Fehse, B., 10.09.2021, In: MOL THER-METH CLIN D. 22, p. 249-262 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44(+)) and T (HLA-DR(+)) cells.
Lioznov, M., El-Cheikh, J., Hoffmann, F., Hildebrandt, Y., Ayuketang Ayuk, F., Wolschke, C., Atanackovic, D., Schilling, G., Badbaran, A., Bacher, U., Fehse, B., Zander, A. R., Blaise, D., Mohty, M. & Kröger, N., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.
Riecken, K., Mock, U., Petrowitz, B., Bartsch, U. & Fehse, B., 2009, In: GENE THER.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells
Hossain, J. A., Ystaas, L. R., Mrdalj, J., Välk, K., Riecken, K., Fehse, B., Bjerkvig, R., Grønli, J. & Miletic, H., 09.2016, In: J GENE MED. 18, 9, p. 234-43 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis
Modlich, U., Kustikova, O. S., Schmidt, M., Rudolph, C., Meyer, J., Li, Z., Kamino, K., von Neuhoff, N., Schlegelberger, B., Kuehlcke, K., Bunting, K. D., Schmidt, S., Deichmann, A., von Kalle, C., Fehse, B. & Baum, C., 01.06.2005, In: BLOOD. 105, 11, p. 4235-46 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limitations and challenges of genetic barcode quantification
Thielecke, L., Aranyossy, T., Dahl, A., Tiwari, R., Roeder, I., Geiger, H., Fehse, B., Glauche, I. & Cornils, K., 03.03.2017, In: SCI REP-UK. 7, p. 43249Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models
Frenzel, T., Siekmann, J., Grohmann, C., Valentiner, U., Schmitz, R., Riecken, K., Fehse, B., Schumacher, U., Lange, T. & Krüll, A., 15.03.2018, In: INT J RADIAT ONCOL. 100, 4, p. 1044-1056 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term in vivo single-cell tracking reveals the switch of migration patterns in adult-born juxtaglomerular cells of the mouse olfactory bulb
Liang, Y., Li, K., Riecken, K., Maslyukov, A., Gomez-Nicola, D., Kovalchuk, Y., Fehse, B. & Garaschuk, O., 07.2016, In: CELL RES. 26, 7, p. 805-21 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma
Hossain, J. A., Latif, M. A., Ystaas, L. A. R., Ninzima, S., Riecken, K., Muller, A., Azuaje, F., Joseph, J. V., Talasila, K. M., Ghimire, J., Fehse, B., Bjerkvig, R. & Miletic, H., 11.07.2019, In: NEURO-ONCOLOGY. 21, 7, p. 890-900 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low-dose thalidomide and donor lymphocyte infusion as adoptive immunotherapy after allogeneic stem cell transplantation in patients with multiple myeloma.
Kröger, N-M., Shimoni, A., Zagrivnaja, M., Ayuketang Ayuk, F., Lioznov, M., Schieder, H., Renges, H-H., Fehse, B., Zabelina, T., Nagler, A. & Zander, A., 2004, In: BLOOD. 104, 10, p. 3361-3363 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low frequency of calreticulin mutations in MDS patients
Heuser, M., Panagiota, V., Koenecke, C., Fehse, B., Alchalby, H., Badbaran, A., Shahswar, R., Stadler, M., Eder, M., Göhring, G., Trummer, A., Schroeder, T., Kobbe, G., Thiede, C., Platzbecker, U., Schlegelberger, B., Kroeger, N., Ganser, A. & Thol, F., 21.05.2014, In: LEUKEMIA.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation.
Vafaizadeh, V., Klemmt, P., Brendel, C., Riecken, K., Doebele, C., Britt, K., Grez, M., Fehse, B., Desriviéres, S. & Groner, B., 2010, In: STEM CELLS. 28, 5, p. 928-938 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology
Selich, A., Daudert, J., Hass, R., Philipp, F., von Kaisenberg, C., Paul, G., Cornils, K., Fehse, B., Rittinghausen, S., Schambach, A. & Rothe, M., 05.2016, In: STEM CELL TRANSL MED. 5, 5, p. 591-601 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Membrane-anchored peptide inhibits human immunodeficiency virus entry
Hildinger, M., Dittmar, M. T., Schult-Dietrich, P., Fehse, B., Schnierle, B. S., Thaler, S., Stiegler, G., Welker, R. & von Laer, D., 03.2001, In: J VIROL. 75, 6, p. 3038-42 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal stem cells engineering: microcapsules assisted gene transfection and magnetic cell separation.
Muslimov, A. R., Timin, A. S., Petrova, AV., Epifanovskaya, O. S., Shakirova, A. I., Lepik, K. V., Gorshkov, A., Il’inskaja, EV., Vasin, A. V., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 2017, In: ACS BIOMATER SCI ENG. 3, 10, p. 2314-2324Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal Stromal/Stem Cells Do Not Ameliorate Experimental Autoimmune Encephalomyelitis and Are Not Detectable in the Central Nervous System of Transplanted Mice
Abramowski, P., Krasemann, S., Ernst, T., Lange, C., Ittrich, H., Schweizer, M., Zander, A. R., Martin, R. & Fehse, B., 01.08.2016, In: STEM CELLS DEV. 25, 15, p. 1134-48Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling
Barry-Carroll, L., Greulich, P., Marshall, A. R., Riecken, K., Fehse, B., Askew, K. E., Li, K., Garaschuk, O., Menassa, D. A. & Gomez-Nicola, D., 30.05.2023, In: CELL REP. 42, 5, p. 112425Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microglia regulate hippocampal neurogenesis during chronic neurodegeneration
De Lucia, C., Rinchon, A., Olmos-Alonso, A., Riecken, K., Fehse, B., Boche, D., Perry, V. H. & Gomez-Nicola, D., 07.2016, In: BRAIN BEHAV IMMUN. 55, p. 179-190Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease diagnostics and chimerism in the post-transplant period in acute myeloid leukemia.
Bacher, U., Haferlach, T., Fehse, B., Schnittger, S. & Kröger, N., 2011, In: SCI WORLD J. 11, p. 310-319Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease diagnostics in myeloid malignancies in the post transplant period.
Bacher, U., Zander, A. R., Haferlach, T., Schnittger, S., Fehse, B. & Kröger, N., 2008, In: BONE MARROW TRANSPL. 42, 3, p. 145-157 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease diagnostics in patients with acute myeloid leukemia in the post-transplant period: comparison of peripheral blood and bone marrow analysis.
Stahl, T., Badbaran, A., Kröger, N., Klyuchnikov, E., Zabelina, T., Zeschke, S., Schafhausen, P., Schultz, W., Asenova, S., Smirnova, A., Wolschke, C., Ayuketang Ayuk, F., Zander, A. R., Fehse, B. & Bacher, U., 01.10.2010, In: LEUKEMIA LYMPHOMA. 51, 10, p. 1837-1843 7 p., 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular methods for detection and quantification of myeloma cells after bone marrow transplantation: comparison between real-time quantitative and nested PCR
Tögel, F., Kröger, N., Korioth, F., Fehse, B. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 971-976 6 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor-T cell therapy
Berger, S. C., Fehse, B., Akyüz, N., Geffken, M., Wolschke, C., Janson, D., Gagelmann, N., Luther, M., Wichmann, D., Frenzel, C., Thayssen, G., Alegiani, A., Badbaran, A., Zeschke, S., Dierlamm, J., Kröger, N. & Ayuk, F. A., 01.02.2023, In: HAEMATOLOGICA. 108, 2, p. 444-456 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring of minimal residual disease in multiple myeloma after allo-SCT: flow cytometry vs PCR-based techniques.
Lioznov, M., Badbaran, A., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2008, In: BONE MARROW TRANSPL. 41, 10, p. 913-916 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring of the JAK2-V617F mutation by highly sensitive quantitative real-time PCR after allogeneic stem cell transplantation in patients with myelofibrosis.
Kröger, N., Badbaran, A., Holler, E., Hahn, J., Kobbe, G., Bornhäuser, M., Reiter, A., Zabelina, T., Zander, A. R. & Fehse, B., 2007, In: BLOOD. 109, 3, p. 1316-1321 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5
Mock, U., Machowicz, R., Hauber, I., Horn, S., Abramowski, P., Berdien, B., Hauber, J. & Fehse, B., 11.05.2015, In: NUCLEIC ACIDS RES. 43, 11, p. 5560-5571Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
mRNA Transfection of T-Lymphocytes by Electroporation
Schwarze, L-I. & Fehse, B., 2021, In: Methods Mol Biol. 2285, p. 217-226 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multicolor RGB Marking Allows Morphometric and Functional Analysis of Hippocampal Granule Neurons at the Single-Cell Level
Gomez-Nicola, D., Riecken, K., Perry, V. H. & Fehse, B., 20.04.2015, In: HUM GENE THER. 26, 6, p. 332-333Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model
Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In: ONCOTARGET. 8, 70, p. 115582-115595 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiple genes surrounding Bcl-xL, a common retroviral insertion site, can influence hematopoiesis individually or in concert
Ha, T-C., Stahlhut, M., Rothe, M., Paul, G., Dziadek, V., Morgan, M. A., Brugman, M., Fehse, B., Kustikova, O., Schambach, A. & Baum, C., 05.2021, In: HUM GENE THER. 32, 9-10, p. 458-472 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiplexing clonality: combining RGB marking and genetic barcoding
Cornils, K., Thielecke, L., Hüser, S., Forgber, M., Thomaschewski, M., Kleist, N., Hussein, K., Riecken, K., Volz, T., Gerdes, S., Glauche, I., Dahl, A., Dandri, M., Roeder, I. & Fehse, B., 01.04.2014, In: NUCLEIC ACIDS RES. 42, 7, p. e56Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Murine leukemia induced by retroviral gene marking
Li, Z., Düllmann, J., Schiedlmeier, B., Schmidt, M., von Kalle, C., Meyer, J., Forster, M., Stocking, C., Wahlers, A., Frank, O., Ostertag, W., Kühlcke, K., Eckert, H-G., Fehse, B. & Baum, C., 19.04.2002, In: SCIENCE. 296, 5567, p. 497Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.
Baum, C., Kustikova, O., Modlich, U., Li, Z. & Fehse, B., 2006, In: HUM GENE THER. 17, 3, p. 253-263 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutagenesis by retroviral transgene insertion: risk assessment and potential alternatives
Baum, C. & Fehse, B., 10.2003, In: Current opinion in molecular therapeutics. 5, 5, p. 458-62 5 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Nanobody-based CD38-specific heavy chain antibodies induce killing of multiple myeloma and other hematological malignancies
Schriewer, L., Schütze, K., Petry, K., Hambach, J., Fumey, W., Koenigsdorf, J., Baum, N., Menzel, S., Rissiek, B., Riecken, K., Fehse, B., Röckendorf, J. L., Schmid, J., Albrecht, B., Pinnschmidt, H., Ayuk, F., Kröger, N., Binder, M., Schuch, G., Hansen, T., Haag, F., Adam, G., Koch-Nolte, F. & Bannas, P., 2020, In: THERANOSTICS. 10, 6, p. 2645-2658 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies
Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In: MOL CANCER THER. 18, 4, p. 823-833 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients
Hagemann, K., Riecken, K., Jung, J., Hildebrandt, H., Menzel, S., Bunders, M., Fehse, B., Koch-Nolte, F., Heinrich, F., Peine, S., Schulze Zur Wiesch, J., Brehm, T. T., Addo, M. M., Lütgehetmann, M. & Altfeld, M., 08.2022, In: EUR J IMMUNOL. 52, 8, p. 1297-1307 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neubewertung des Schutzes von In-vitro-Embryonen in Deutschland
Bartram, C. R., Ellenberg, J., Fehse, B., Friedrich, B., Kentenich, H., Kumsta, R., Niehrs, C., Nöthen, M. M., Schöne-Seifert, B., Tanner, K., Taupitz, J., Thorn, P., Vogel, J., Wiesemann, C. & Winnacker, E-L., 2021Research output: Memorandum/exposition › Academic memorandum
Neue Wege der Stammzellforschung: Reprogrammierung von differenzierten Körperzellen
Beier, HM., Fehse, B., Friedrich, B., Götz, M., Hansmann, I., Hucho, F., Köchy, K., Müller-Röber, B., Rheinberger, HJ., Reich, J., Robpers, HH., Schöler, HR., Schöne-Seifert, B., Sperling, K., Tanner, K., Taupitz, J. & Wobus, AM., 2010, In: J Reprodmed Endokrinol. 7, p. 68-77Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neural stem cell-based intraocular administration of ciliary neurotrophic factor attenuates the loss of axotomized ganglion cells in adult mice
Flachsbarth, K., Kruszewski, K., Jung, G., Jankowiak, W., Riecken, K., Wagenfeld, L., Richard, G., Fehse, B. & Bartsch, U., 2014, In: INVEST OPHTH VIS SCI. 55, 11, p. 7029-7039Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
Mock, U., Riecken, K., Berdien, B., Qasim, W., Chan, E., Cathomen, T. & Fehse, B., 01.01.2014, In: SCI REP-UK. 4, p. 6409Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Obituary Rolf Neth 1926-2020
Fehse, B., Kröger, N., Stocking, C. & Zander, A., 05.2020, In: Experimental hematology. 85, p. 1-2 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer
Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity
Mohme, M., Maire, C. L., Riecken, K., Zapf, S., Aranyossy, T., Westphal, M., Lamszus, K. & Fehse, B., 01.03.2017, In: MOL THER. 25, 3, p. 621-633Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
Schwarze, L. I., Głów, D., Sonntag, T., Uhde, A. & Fehse, B., 09.2021, In: GENE THER. 28, 9, p. 588-601 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods
Mashel, T. V., Tarakanchikova, Y. V., Muslimov, A. R., Zyuzin, M. V., Timin, A. S., Lepik, K. V. & Fehse, B., 11.2020, In: BIOMATERIALS. 258, p. 120282Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells.
Hoxha, E., Fehse, B., Ortmeyer, G., Stocking, C., Mayr, G. W. & Jücker, M., 2008, In: LEUKEMIA LYMPHOMA. 49, 6, p. 1206-1208 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peri-transplant flow-MRD assessment of cells with leukemic stem cells (LSC) associated phenotype in AML patients undergoing allogeneic stem cell transplantation in CR
Klyuchnikov, E., Badbaran, A., Massoud, R., Freiberger, P., Wolschke, C., Ayuk, F., Fehse, B., Bacher, U. & Kröger, N., 02.2024, In: LEUKEMIA. 38, 2, p. 386-388 3 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Persisting multilineage transgene expression in the clonal progeny of a hematopoietic stem cell
Li, Z., Fehse, B., Schiedlmeier, B., Düllmann, J., Frank, O., Zander, A. R., Ostertag, W. & Baum, C., 09.2002, In: LEUKEMIA. 16, 9, p. 1655-63 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pois(s)on--it's a question of dose
Fehse, B., Kustikova, O. S., Bubenheim, M. & Baum, C., 06.2004, In: GENE THER. 11, 11, p. 879-81 3 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Population Pharmacokinetics of Busulfan and Its Metabolite Sulfolane in Patients with Myelofibrosis Undergoing Hematopoietic Stem Cell Transplantation
Dadkhah, A., Wicha, S. G., Kröger, N., Müller, A., Pfaffendorf, C., Riedner, M., Badbaran, A., Fehse, B. & Langebrake, C., 27.05.2022, In: PHARMACEUTICS. 14, 6, 1145.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Post-transplant immunotherapy with donor-lymphocyte infusion and novel agents to upgrade partial into complete and molecular remission in allografted patients with multiple myeloma.
Kröger, N., Badbaran, A., Lioznov, M., Schwartz, S., Zeschke, S., Hildebrandt, Y., Ayuketang Ayuk, F., Atanackovic, D., Schilling, G., Zabelina, T., Bacher, U., Klyuchnikov, E., Shimoni, A., Nagler, A., Corradini, P., Fehse, B. & Zander, A. R., 2009, In: EXP HEMATOL. 37, 7, p. 791-798 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins
Schieferdecker, A., Shoshani, O., Westner, B., Zipori, D., Fehse, B., Kröger, N. & Ayuketang, F. A., 11.10.2016, In: ONCOTARGET. 7, 41, p. 67061-67070Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose
Li, Z., Schwieger, M., Lange, C., Kraunus, J., Sun, H., van den Akker, E., Modlich, U., Serinsöz, E., Will, E., von Laer, D., Stocking, C., Fehse, B., Schiedlmeier, B. & Baum, C., 01.12.2003, In: Experimental hematology. 31, 12, p. 1206-14 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer
Bierwolf, J., Volz, T., Lütgehetmann, M., Allweiss, L., Riecken, K., Warlich, M., Fehse, B., Kalff, J. C., Dandri-Petersen, M. & Pollok, J-M., 05.2016, In: TISSUE ENG PT A. 22, 9-10, p. 742-53 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene
Zhan, H., Gilmour, K., Chan, L., Farzaneh, F., McNicol, A. M., Xu, J-H., Adams, S., Fehse, B., Veys, P., Thrasher, A., Gaspar, H. & Qasim, W., 01.01.2013, In: PLOS ONE. 8, 10, p. e77106Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation
Panagiota, V., Thol, F., Markus, B., Fehse, B., Alchalby, H., Badbaran, A., Lehmann, U., Koenecke, C., Shahswar, R., Chaturvedi, A., Stadler, M., Eder, M., Göhring, G., Koenigsmann, M., Kloos, A., Trummer, A., Schroeder, T., Kobbe, G., Thiede, C., Platzbecker, U., Schlegelberger, B., Kreipe, H-H., Ganser, A., Kröger, N. & Heuser, M., 01.07.2014, In: LEUKEMIA. 28, 7, p. 1552-5 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Purging and haemopoietic progenitor cell selection by CD34+ cell separation
Krüger, W., Gruber, M., Hennings, S., Fehse, N., Fehse, B., Gutensohn, K., Kröger, N. & Zander, A. R., 04.1998, In: BONE MARROW TRANSPL. 21, 7, p. 665-671 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation
Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.
Bacher, U., Badbaran, A., Fehse, B., Zabelina, T., Zander, A. R. & Kröger, N., 2009, In: EXP HEMATOL. 37, 1, p. 135-142 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid and efficient cloning of proviral flanking fragments by kanamycin resistance gene complementation
Fehse, B., Kühlcke, K., Langer, A., Ostertag, W. & Lother, H., 15.01.1999, In: NUCLEIC ACIDS RES. 27, 2, p. 706-7 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.
Metzner, A., Precht, C., Fehse, B., Fiedler, W., Stocking, C., Günther, A., Mayr, G. W. & Jücker, M., 2009, In: GENE THER. 16, 4, p. 570-573 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA.
Meyer, J., Rhein, M., Schiedlmeier, B., Kustikova, O., Rudolph, C., Kamino, K., Neumann, T., Yang, M., Wahlers, A., Fehse, B., Reuther, G. W., Schlegelberger, B., Ganser, A., Baum, C. & Li, Z., 2007, In: LEUKEMIA. 21, 10, p. 2171-2180 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resistance of mature T cells to oncogene transformation.
Newrzela, S., Cornils, K., Li, Z., Baum, C., Brugman, M. H., Hartmann, M., Meyer, J., Hartmann, S., Hansmann, M-L., Fehse, B. & von Laer, D., 2008, In: BLOOD. 112, 6, p. 2278-2286 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retrovirale Vektoren – Effiziente Gentaxis für unterschiedliche Gentherapien
Morgan, M. A., Galla, M., Fehse, B. & Schambach, A., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 25-49 25 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Retroviral gene therapy in Germany with a view on previous experience and future perspectives
Morgan, M. A., Galla, M., Grez, M., Fehse, B. & Schambach, A., 09.2021, In: GENE THER. 28, 9, p. 494-512 19 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.
Newrzela, S., Cornils, K., Heinrich, T., Schläger, J., Yi, J-H., Lysenko, O., Kimpel, J., Fehse, B. & Dorothee, V. L., 2011, In: MOL MED. 17, 11-12, p. 1223-1232 11-12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis
Heim, D., Cornils, K., Schulze, K., Fehse, B., Lohse, A. W., Brümmendorf, T. H. & Wege, H., 2015, In: ONCOGENE. 34, 3, p. 385-393Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertion site analysis in dominant haematopoietic clones.
Kustikova, O. S., Modlich, U. & Fehse, B., 2009, In: Methods Mol Biol. 506, p. 373-390Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral integration site analysis in hematopoietic stem cells.
Kustikova, O. S., Baum, C. & Fehse, B., 2008, In: Methods Mol Biol. 430, p. 255-267Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions.
Giordano, F. A., Fehse, B., Hotz-Wagenblatt, A., Jonnakuty, S., Del Val, C., Appelt, J-U., Nagy, K. Z., Kuehlcke, K., Naundorf, S., Zander, A. R., Zeller, W. J., Ho, A. D., Fruehauf, S. & Laufs, S., 2006, In: BONE MARROW TRANSPL. 38, 3, p. 229-235 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
Kustikova, O. S., Geiger, H., Li, Z., Brugman, M. H., Chambers, S. M., Shaw, C. A., Pike-Overzet, K., de Ridder, D., Staal, F. J. T., von Keudell, G., Cornils, K., Nattamai, K. J., Modlich, U., Wagemaker, G., Goodell, M. A., Fehse, B. & Baum, C., 2007, In: BLOOD. 109, 5, p. 1897-1907 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Michaelis, M., Rothweiler, F., Klassert, D., von Deimling, A., Riecken, K., Fehse, B., Kammerer, B., Doerr, H. W. & Cinatl, J., 2009, In: CANCER RES. 69, 2, p. 416-421 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking facilitates multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking : Vielfarbige Zellmarkierung zur klonalen Analyse
Riecken, K., Thomaschewski, M., Warlich, M., Cornils, K., Benten, D. & Fehse, B., 2012, In: Laborwelt. 13, 1, p. 7-9 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking with lentiviral vectors for multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Benten, D. & Fehse, B., 2012, In: NAT PHYS. 7, 5, p. 839-849 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma
Waizenegger, J. S., Ben-Batalla, I., Weinhold, N., Meissner, T., Wroblewski, M., Janning, M., Riecken, K., Binder, M., Atanackovic, D., Taipaleenmaeki, H., Schewe, D., Sawall, S., Gensch, V., Cubas-Cordova, M., Seckinger, A., Fiedler, W., Hesse, E., Kröger, N., Fehse, B., Hose, D., Klein, B., Raab, M. S., Pantel, K., Bokemeyer, C. & Loges, S., 01.03.2015, In: LEUKEMIA. 29, 3, p. 696-704 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
„Rote Gentechnologie“ – Nachhaltiges Comeback der Gentherapie?!
Fehse, B., 2018, Vierter Gentechnologiebericht : Bilanzierung einer Hochtechnologie. Hucho, F., Diekämper, J., Fangerau, H., Fehse, B., Hampel, J., Köchy, K., Könninger, S., Marx-Stölting, L., Müller-Röber, B., Reich, J., Schickl, H., Taupitz, J., Walter, J., Zenke, M. & Korte, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 210-214 5 p. (Forschungsberichte der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 40).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCT.
Alchalby, H., Badbaran, A., Bock, O., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: BONE MARROW TRANSPL. 45, 9, p. 1404-1407 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening of Potential HIV-1 Inhibitors/Replication Blockers Using Secure Lentiviral in Vitro System.
Prokofjeva, M. M., Spirin, P. V., Yanvarev, D. V., Ivanov, A. V., Novikov, M. S., Stepanov, O. A., Gottikh, M. B., Kochetkov, S. N., Fehse, B., Stocking, C. & Prassolov, V. S., 2012, In: ACTA NATURAE. 3, 4, p. 55-65 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selectins mediate small cell lung cancer systemic metastasis
Heidemann, F., Schildt, A., Schmid, K., Bruns, O. T., Riecken, K., Jung, C., Ittrich, H., Wicklein, D., Reimer, R., Fehse, B., Heeren, J., Lüers, G., Schumacher, U. & Heine, M., 01.01.2014, In: PLOS ONE. 9, 4, p. e92327Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selective immunoaffinity-based enrichment of CD34+ cells transduced with retroviral vectors containing an intracytoplasmatically truncated version of the human low-affinity nerve growth factor receptor (deltaLNGFR) gene
Fehse, B., Uhde, A., Fehse, N., Eckert, H. G., Clausen, J., Rüger, R., Koch, S., Ostertag, W., Zander, A. R. & Stockschläder, M., 10.10.1997, In: HUM GENE THER. 8, 15, p. 1815-1824 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Self-inactivating retroviral vectors with improved RNA processing
Kraunus, J., Schaumann, D. H. S., Meyer, J., Modlich, U., Fehse, B., Brandenburg, G., von Laer, D., Klump, H., Schambach, A., Bohne, J. & Baum, C., 11.2004, In: GENE THER. 11, 21, p. 1568-78 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensitive balance of suppressing and activating effects of mesenchymal stem cells on T-cell proliferation.
Fang, L., Lange, C., Engel, M., Zander, A. R. & Fehse, B., 2006, In: TRANSPLANTATION. 82, 10, p. 1370-1373 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model
Täger, M., Horn, S., Latuske, E., Ehm, P., Schaks, M., Nalaskowski, M., Fehse, B., Fiedler, W., Stocking, C., Wellbrock, J. & Jücker, M., 11.2017, In: GENE THER. 24, 11, p. 749-753 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Side effects of retroviral gene transfer into hematopoietic stem cells
Baum, C., Düllmann, J., Li, Z., Fehse, B., Meyer, J., Williams, D. A. & von Kalle, C., 15.03.2003, In: BLOOD. 101, 6, p. 2099-114 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Similar outcome of calreticulin type I and calreticulin type II mutations following RIC allogeneic haematopoietic stem cell transplantation for myelofibrosis
Christopeit, M., Badbaran, A., Zabelina, T., Zeck, G., Fehse, B., Ayuketang, F. A., Wolschke, C. & Kröger, N-M., 10.2016, In: BONE MARROW TRANSPL. 51, 10, p. 1391-1393 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Simplified generation of high-titer retrovirus producer cells for clinically relevant retroviral vectors by reversible inclusion of a lox-P-flanked marker gene
Loew, R., Selevsek, N., Fehse, B., von Laer, D., Baum, C., Fauser, A. & Kuehlcke, K., 05.2004, In: MOL THER. 9, 5, p. 738-46 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
von Wenserski, L., Schultheiß, C., Bolz, S., Schliffke, S., Simnica, D., Willscher, E., Gerull, H., Wolters-Eisfeld, G., Riecken, K., Fehse, B., Altfeld, M., Nollau, P. & Binder, M., 04.2021, In: LEUKEMIA. 35, 4, p. 1073-1086 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SOCS3 promotes interleukin-17 expression of human T cells.
Kleinsteuber, K., Heesch, K., Schattling, S., Sander-Juelch, C., Mock, U., Riecken, K., Fehse, B., Fleischer, B. & Jacobsen, M., 2012, In: BLOOD. 120, 22, p. 4374-4382 22.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spleen volume and length determined by computed tomography impact outcome after allogeneic stem cell transplantation for myelofibrosis
Luther, M., Henes, F. O., Zabelina, T., Massoud, R., Janson, D., Wolschke, C., Klyuchnikov, E., Gagelmann, N., Fehse, B., Adam, G., Kröger, N. & Ayuk, F., 07.2023, In: BONE MARROW TRANSPL. 58, 7, p. 755-761 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stand wissenschaftlicher und medizinischer Entwicklungen
Fehse, B., Baum, C., Schmidt, M. & Kalle, C., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 41-126 86 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Stem cell clonality and genotoxicity in hematopoietic cells: gene activation side effects should be avoidable
von Kalle, C., Fehse, B., Layh-Schmitt, G., Schmidt, M., Kelly, P. & Baum, C., 10.2004, In: SEMIN HEMATOL. 41, 4, p. 303-18 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Stem cell clonality -- theoretical concepts, experimental techniques, and clinical challenges
Glauche, I., Bystrykh, L., Eaves, C., Roeder, I. & other participants, 01.04.2013, In: BLOOD CELL MOL DIS. 50, 4, p. 232-40 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.
Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Suicide gene therapy for the treatment of high-grade glioma: past lessons, present trends, and future prospects
Hossain, J. A., Marchini, A., Fehse, B., Bjerkvig, R. & Miletic, H., 10.07.2020, In: NEURO-ONCOL ADV. 2, 1, p. vdaa013Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Syngenic graft-versus-chronic-myeloid-leukemia-effect?
Ocheni, S., Schafhausen, P., Bacher, U., Fehse, B. & Kröger, N., 2009, In: CTT-Cell Ther Transpl. 1, 3, p. 66-68 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer
Berdien, B., Mock, U., Atanackovic, D. & Fehse, B., 27.03.2014, In: GENE THER. 21, p. 539–548Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)
Hambach, J., Riecken, K., Cichutek, S., Schütze, K., Albrecht, B., Petry, K., Röckendorf, J. L., Baum, N., Kröger, N., Hansen, T., Schuch, G., Haag, F., Adam, G., Fehse, B., Bannas, P. & Koch-Nolte, F., 29.01.2020, In: CELLS-BASEL. 9, 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting species D adenoviruses replication to counteract the epidemic keratoconjunctivitis
Nikitenko, N. A., Speiseder, T., Groitl, P., Spirin, P. V., Prokofjeva, M. M., Lebedev, T. D., Rubtsov, P. M., Lam, E., Riecken, K., Fehse, B., Dobner, T. & Prassolov, V. S., 19.03.2015, In: BIOCHIMIE. 113, p. 10-16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration
Gomez-Nicola, D., Suzzi, S., Vargas-Caballero, M., Fransen, N. L., Al-Malki, H., Cebrian-Silla, A., Garcia-Verdugo, J. M., Riecken, K., Fehse, B. & Perry, V. H., 01.08.2014, In: BRAIN. 137, Pt 8, p. 2312-28 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro
Horn, S., Meyer, J., Heukeshoven, J., Fehse, B., Schulze, C., Li, S., Frey, J., Poll, S., Stocking, C. & Jücker, M., 01.2001, In: LEUKEMIA. 15, 1, p. 112-20 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Themenbereich somatische Gentherapie: aus dem Labor über klinische Studien zum kommerziellen Einsatz
Fehse, B., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 156-183 28 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Themenbereich somatische Gentherapie: Translationale und klinische Forschung
Fehse, B. & Domasch, S., 2015, Dritter Gentechnologiebericht: Analyse einer Hochtechnologie. Müller-Röber, B., Budisa, N., Diekämper, J., Domasch, S., Fehse, B., Hampel, J., Hucho, F., Hümpel, A., Köchy, K., Marx-Stölting, L., Reich, J., Rheinberger, H-J., Ropers, H-H., Taupitz, J., Walter, J. & Zenke, M. (eds.). 1 ed. Baden Baden: Nomos, p. 211-308 98 p. (Forschungsberichte der Interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 32).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia
Schliffke, S., Buhs, S., Bolz, S., Gerull, H., von Wenserski, L., Riecken, K., Fehse, B., Nollau, P. & Binder, M., 12.04.2018, In: BLOOD. 131, 15, p. 1755-1758 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age
Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Time Is Ripe for Somatic Genome Editing: NIH Program to Strengthen Translation
Fehse, B. & Abramowski-Mock, U., 07.03.2018, In: MOL THER. 26, 3, p. 671-674 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
