Prof. Dr. ID: 65683
Boris Fehse
Publications
- 2008
Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Panse, J., Wolschke, C., Eiermann, T., Binder, T., Fehse, B., Erttmann, R., Kabisch, H., Bacher, U., Kröger, N. & Zander, A. R., 2008, In: EXP HEMATOL. 36, 8, p. 1047-1054 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation.
Atanackovic, D., Cao, Y., Luetkens, T., Panse, J., Faltz, C., Arfsten, J., Bartels, K., Wolschke, C., Eiermann, T., Zander, A. R., Fehse, B., Bokemeyer, C. & Kröger, N., 2008, In: HAEMATOLOGICA. 93, 3, p. 423-430 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical application of a retroviral gene transfer protocol based on centrifugation-mediated vector preloading.
Fehse, B., 2008, In: HUM GENE THER. 19, 6, p. 655-658 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of two doses of antithymocyte globulin in patients undergoing matched unrelated donor allogeneic stem cell transplantation.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Wolschke, C., Fehse, B., Bacher, U., Erttmann, R., Kröger, N. & Zander, A. R., 2008, In: BIOL BLOOD MARROW TR. 14, 8, p. 913-919 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Complement-dependent and complement-independent cytotoxicity of polyclonal antithymocyte globulins in chronic lymphocytic leukemia.
Ayuketang Ayuk, F., Atassi, N., Schuch, G., Mina, S., Fang, L., Bokemeyer, C., Fehse, B., Zander, A. R. & Kröger, N., 2008, In: LEUKEMIA RES. 32, 8, p. 1200-1206 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differences in proportion and dynamics of recipient hematopoiesis following hematopoietic cell transplantation in CML and IMF.
Siebolts, U., Thiele, J., Zander, T., Ditschkowski, M., Beelen, D. W., Kröger, N., Fehse, B. & Wickenhauser, C., 2008, In: ONCOL REP. 19, 1, p. 287-292 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insertional mutagenesis and clonal dominance: biological and statistical considerations.
Fehse, B. & Roeder, I., 2008, In: GENE THER. 15, 2, p. 143-153 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease diagnostics in myeloid malignancies in the post transplant period.
Bacher, U., Zander, A. R., Haferlach, T., Schnittger, S., Fehse, B. & Kröger, N., 2008, In: BONE MARROW TRANSPL. 42, 3, p. 145-157 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring of minimal residual disease in multiple myeloma after allo-SCT: flow cytometry vs PCR-based techniques.
Lioznov, M., Badbaran, A., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2008, In: BONE MARROW TRANSPL. 41, 10, p. 913-916 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells.
Hoxha, E., Fehse, B., Ortmeyer, G., Stocking, C., Mayr, G. W. & Jücker, M., 2008, In: LEUKEMIA LYMPHOMA. 49, 6, p. 1206-1208 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resistance of mature T cells to oncogene transformation.
Newrzela, S., Cornils, K., Li, Z., Baum, C., Brugman, M. H., Hartmann, M., Meyer, J., Hartmann, S., Hansmann, M-L., Fehse, B. & von Laer, D., 2008, In: BLOOD. 112, 6, p. 2278-2286 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral integration site analysis in hematopoietic stem cells.
Kustikova, O. S., Baum, C. & Fehse, B., 2008, In: Methods Mol Biol. 430, p. 255-267Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transportation and cryopreservation may impair haematopoietic stem cell function and engraftment of allogeneic PBSCs, but not BM.
Lioznov, M., Dellbrügger, C., Sputtek, A., Fehse, B., Kröger, N. & Zander, A. R., 2008, In: BONE MARROW TRANSPL. 42, 2, p. 121-128 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.
Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study.
Lippert, E., Girodon, F., Hammond, E., Jelinek, J., Reading, N. S., Fehse, B., Hanlon, K., Hermans, M., Richard, C., Swierczek, S., Ugo, V., Carillo, S., Harrivel, V., Marzac, C., Pietra, D., Sobas, M., Mounier, M., Migeon, M., Ellard, S., Kröger, N., Herrmann, R., Prchal, J. T., Skoda, R. C. & Hermouet, S., 2009, In: HAEMATOLOGICA. 94, 1, p. 38-45 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diva-Fit: A step-by-step manual for generating high-resolution graphs and histogram overlays of flow cytometry data obtained with FACSDiva software
Riecken, K. & Fehse, B., 2009, In: CTT-Cell Ther Transpl. 1, 4, p. 1-4 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation.
Kröger, N., Alchalby, H., Klyuchnikov, E., Badbaran, A., Hildebrandt, Y., Ayuketang Ayuk, F., Bacher, U., Bock, O., Kvasnicka, M., Fehse, B. & Zander, A. R., 2009, In: BLOOD. 113, 8, p. 1866-1868 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44(+)) and T (HLA-DR(+)) cells.
Lioznov, M., El-Cheikh, J., Hoffmann, F., Hildebrandt, Y., Ayuketang Ayuk, F., Wolschke, C., Atanackovic, D., Schilling, G., Badbaran, A., Bacher, U., Fehse, B., Zander, A. R., Blaise, D., Mohty, M. & Kröger, N., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.
Riecken, K., Mock, U., Petrowitz, B., Bartsch, U. & Fehse, B., 2009, In: GENE THER.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Post-transplant immunotherapy with donor-lymphocyte infusion and novel agents to upgrade partial into complete and molecular remission in allografted patients with multiple myeloma.
Kröger, N., Badbaran, A., Lioznov, M., Schwartz, S., Zeschke, S., Hildebrandt, Y., Ayuketang Ayuk, F., Atanackovic, D., Schilling, G., Zabelina, T., Bacher, U., Klyuchnikov, E., Shimoni, A., Nagler, A., Corradini, P., Fehse, B. & Zander, A. R., 2009, In: EXP HEMATOL. 37, 7, p. 791-798 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.
Bacher, U., Badbaran, A., Fehse, B., Zabelina, T., Zander, A. R. & Kröger, N., 2009, In: EXP HEMATOL. 37, 1, p. 135-142 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.
Metzner, A., Precht, C., Fehse, B., Fiedler, W., Stocking, C., Günther, A., Mayr, G. W. & Jücker, M., 2009, In: GENE THER. 16, 4, p. 570-573 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertion site analysis in dominant haematopoietic clones.
Kustikova, O. S., Modlich, U. & Fehse, B., 2009, In: Methods Mol Biol. 506, p. 373-390Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Michaelis, M., Rothweiler, F., Klassert, D., von Deimling, A., Riecken, K., Fehse, B., Kammerer, B., Doerr, H. W. & Cinatl, J., 2009, In: CANCER RES. 69, 2, p. 416-421 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.
Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Syngenic graft-versus-chronic-myeloid-leukemia-effect?
Ocheni, S., Schafhausen, P., Bacher, U., Fehse, B. & Kröger, N., 2009, In: CTT-Cell Ther Transpl. 1, 3, p. 66-68 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells.
Rothweiler, F., Michaelis, M., Brauer, P., Otte, J., Riecken, K., Fehse, B., Doerr, H. W., Wiese, M., Kreuter, J., Al-Abed, Y., Nicoletti, F. & Cinatl, J., 2010, In: NEOPLASIA. 12, 12, p. 1023-1030 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).
Stocking, C., Grez, M., Fehse, B., von Laer, D., Itoh, K., Prassolov, V., Nowock, J., Kühlcke, K., Just, U., Schröder, T., Klump, H., Schiedlmeier, B., Grassman, E., Meyer, J., Li, Z., Schambach, A., Modlich, U., Kustikova, O., Galla, M., Jürgen, B., Zander, A. R. & Baum, C., 2010, In: HUM GENE THER. 21, 11, p. 1501-1503 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia.
Wiedemann, B., Klyuchnikov, E., Kröger, N., Zabelina, T., Stahl, T., Zeschke, S., Badbaran, A., Ayuketang Ayuk, F., Alchalby, H., Wolschke, C., Bokemeyer, C., Fehse, B., Zander, A. R. & Bacher, U., 2010, In: EXP HEMATOL. 38, 12, p. 1261-1271 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Highly efficient lentiviral transduction of phenotypically and genotypically characterized endothelial progenitor cells from adult peripheral blood.
Stockschlaeder, M., Shardakova, O., Riecken, K., Stoldt, V. R., Fehse, B., Giers, G. & Scharf, R. E., 2010, In: BLOOD COAGUL FIBRIN. 21, 5, p. 464-473 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis.
Alchalby, H., Badbaran, A., Zabelina, T., Kobbe, G., Hahn, J., Wolff, D., Bornhäuser, M., Christian, T., Baurmann, H., Bethge, W., Hildebrandt, Y., Bacher, U., Fehse, B., Zander, A. R. & Kröger, N., 2010, In: BLOOD. 116, 18, p. 3572-3581 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation.
Vafaizadeh, V., Klemmt, P., Brendel, C., Riecken, K., Doebele, C., Britt, K., Grez, M., Fehse, B., Desriviéres, S. & Groner, B., 2010, In: STEM CELLS. 28, 5, p. 928-938 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neue Wege der Stammzellforschung: Reprogrammierung von differenzierten Körperzellen
Beier, HM., Fehse, B., Friedrich, B., Götz, M., Hansmann, I., Hucho, F., Köchy, K., Müller-Röber, B., Rheinberger, HJ., Reich, J., Robpers, HH., Schöler, HR., Schöne-Seifert, B., Sperling, K., Tanner, K., Taupitz, J. & Wobus, AM., 2010, In: J Reprodmed Endokrinol. 7, p. 68-77Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCT.
Alchalby, H., Badbaran, A., Bock, O., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: BONE MARROW TRANSPL. 45, 9, p. 1404-1407 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TK.007: A novel, codon-optimized HSVtk(A168H) mutant for suicide gene therapy.
Preuß, E., Treschow, A., Newrzela, S., Brücher, D., Riecken, K., Felldin, U., Alici, E., Gahrton, G., von Laer, D., Dilber, M. S. & Fehse, B., 2010, In: HUM GENE THER. 21, 8, p. 929-941 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of mannose-binding lectin genotypes and serostatus in allo-SCT: analysis of 131 recipients and donors.
Neth, O. W., Bacher, U., Das, P., Zabelina, T., Kabisch, H., Kroeger, N., Ayuketang, F. A., Lioznov, M., Waschke, O., Fehse, B., Thiébaut, R., Haston, R. M., Klein, N. & Zander, A. R., 01.01.2010, In: BONE MARROW TRANSPL. 45, 1, p. 13-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease diagnostics in patients with acute myeloid leukemia in the post-transplant period: comparison of peripheral blood and bone marrow analysis.
Stahl, T., Badbaran, A., Kröger, N., Klyuchnikov, E., Zabelina, T., Zeschke, S., Schafhausen, P., Schultz, W., Asenova, S., Smirnova, A., Wolschke, C., Ayuketang Ayuk, F., Zander, A. R., Fehse, B. & Bacher, U., 01.10.2010, In: LEUKEMIA LYMPHOMA. 51, 10, p. 1837-1843 7 p., 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.
Preuß, E., Muik, A., Riecken, K., Otte, J., von Laer, D. & Fehse, B., 2011, In: J MOL MED. 89, 11, p. 1113-1124 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene therapy strategies: can we eradicate HIV?
van Lunzen, J., Fehse, B. & Hauber, J., 2011, In: CURR HIV-AIDS REP. 8, 2, p. 78-84 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic Modifications – Possibilities and Limits of Gene Therapy
Fehse, B., 2011, Human Nature and Self Design. mentis Verlag Paderborn, p. 113-136 24 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Gentherapie in Deutschland. Eine Einführung
Domasch, S. & Fehse, B., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 31-40 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Minimal residual disease diagnostics and chimerism in the post-transplant period in acute myeloid leukemia.
Bacher, U., Haferlach, T., Fehse, B., Schnittger, S. & Kröger, N., 2011, In: SCI WORLD J. 11, p. 310-319Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.
Newrzela, S., Cornils, K., Heinrich, T., Schläger, J., Yi, J-H., Lysenko, O., Kimpel, J., Fehse, B. & Dorothee, V. L., 2011, In: MOL MED. 17, 11-12, p. 1223-1232 11-12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking facilitates multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stand wissenschaftlicher und medizinischer Entwicklungen
Fehse, B., Baum, C., Schmidt, M. & Kalle, C., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 41-126 86 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells
Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation
Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Efficient lentiviral transduction and transgene expression in primary human B cells.
Mock, U., Thiele, R., Uhde, A., Fehse, B. & Horn, S., 2012, In: HUM GENE THER METHOD. 23, 6, p. 408-415 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review