Prof. Dr. ID: 65683

Boris Fehse

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Publications

  1. 2008
  2. Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.

    Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Panse, J., Wolschke, C., Eiermann, T., Binder, T., Fehse, B., Erttmann, R., Kabisch, H., Bacher, U., Kröger, N. & Zander, A. R., 2008, In: EXP HEMATOL. 36, 8, p. 1047-1054 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation.

    Atanackovic, D., Cao, Y., Luetkens, T., Panse, J., Faltz, C., Arfsten, J., Bartels, K., Wolschke, C., Eiermann, T., Zander, A. R., Fehse, B., Bokemeyer, C. & Kröger, N., 2008, In: HAEMATOLOGICA. 93, 3, p. 423-430 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Clinical application of a retroviral gene transfer protocol based on centrifugation-mediated vector preloading.

    Fehse, B., 2008, In: HUM GENE THER. 19, 6, p. 655-658 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Comparison of two doses of antithymocyte globulin in patients undergoing matched unrelated donor allogeneic stem cell transplantation.

    Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Wolschke, C., Fehse, B., Bacher, U., Erttmann, R., Kröger, N. & Zander, A. R., 2008, In: BIOL BLOOD MARROW TR. 14, 8, p. 913-919 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Complement-dependent and complement-independent cytotoxicity of polyclonal antithymocyte globulins in chronic lymphocytic leukemia.

    Ayuketang Ayuk, F., Atassi, N., Schuch, G., Mina, S., Fang, L., Bokemeyer, C., Fehse, B., Zander, A. R. & Kröger, N., 2008, In: LEUKEMIA RES. 32, 8, p. 1200-1206 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Differences in proportion and dynamics of recipient hematopoiesis following hematopoietic cell transplantation in CML and IMF.

    Siebolts, U., Thiele, J., Zander, T., Ditschkowski, M., Beelen, D. W., Kröger, N., Fehse, B. & Wickenhauser, C., 2008, In: ONCOL REP. 19, 1, p. 287-292 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Insertional mutagenesis and clonal dominance: biological and statistical considerations.

    Fehse, B. & Roeder, I., 2008, In: GENE THER. 15, 2, p. 143-153 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Minimal residual disease diagnostics in myeloid malignancies in the post transplant period.

    Bacher, U., Zander, A. R., Haferlach, T., Schnittger, S., Fehse, B. & Kröger, N., 2008, In: BONE MARROW TRANSPL. 42, 3, p. 145-157 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Monitoring of minimal residual disease in multiple myeloma after allo-SCT: flow cytometry vs PCR-based techniques.

    Lioznov, M., Badbaran, A., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2008, In: BONE MARROW TRANSPL. 41, 10, p. 913-916 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells.

    Hoxha, E., Fehse, B., Ortmeyer, G., Stocking, C., Mayr, G. W. & Jücker, M., 2008, In: LEUKEMIA LYMPHOMA. 49, 6, p. 1206-1208 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Resistance of mature T cells to oncogene transformation.

    Newrzela, S., Cornils, K., Li, Z., Baum, C., Brugman, M. H., Hartmann, M., Meyer, J., Hartmann, S., Hansmann, M-L., Fehse, B. & von Laer, D., 2008, In: BLOOD. 112, 6, p. 2278-2286 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Retroviral integration site analysis in hematopoietic stem cells.

    Kustikova, O. S., Baum, C. & Fehse, B., 2008, In: Methods Mol Biol. 430, p. 255-267

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Transportation and cryopreservation may impair haematopoietic stem cell function and engraftment of allogeneic PBSCs, but not BM.

    Lioznov, M., Dellbrügger, C., Sputtek, A., Fehse, B., Kröger, N. & Zander, A. R., 2008, In: BONE MARROW TRANSPL. 42, 2, p. 121-128 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. 2009
  16. Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.

    Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Concordance of assays designed for the quantification of JAK2V617F: a multicenter study.

    Lippert, E., Girodon, F., Hammond, E., Jelinek, J., Reading, N. S., Fehse, B., Hanlon, K., Hermans, M., Richard, C., Swierczek, S., Ugo, V., Carillo, S., Harrivel, V., Marzac, C., Pietra, D., Sobas, M., Mounier, M., Migeon, M., Ellard, S., Kröger, N., Herrmann, R., Prchal, J. T., Skoda, R. C. & Hermouet, S., 2009, In: HAEMATOLOGICA. 94, 1, p. 38-45 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Diva-Fit: A step-by-step manual for generating high-resolution graphs and histogram overlays of flow cytometry data obtained with FACSDiva software

    Riecken, K. & Fehse, B., 2009, In: CTT-Cell Ther Transpl. 1, 4, p. 1-4 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation.

    Kröger, N., Alchalby, H., Klyuchnikov, E., Badbaran, A., Hildebrandt, Y., Ayuketang Ayuk, F., Bacher, U., Bock, O., Kvasnicka, M., Fehse, B. & Zander, A. R., 2009, In: BLOOD. 113, 8, p. 1866-1868 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44(+)) and T (HLA-DR(+)) cells.

    Lioznov, M., El-Cheikh, J., Hoffmann, F., Hildebrandt, Y., Ayuketang Ayuk, F., Wolschke, C., Atanackovic, D., Schilling, G., Badbaran, A., Bacher, U., Fehse, B., Zander, A. R., Blaise, D., Mohty, M. & Kröger, N., 2009, In: BONE MARROW TRANSPL.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.

    Riecken, K., Mock, U., Petrowitz, B., Bartsch, U. & Fehse, B., 2009, In: GENE THER.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Post-transplant immunotherapy with donor-lymphocyte infusion and novel agents to upgrade partial into complete and molecular remission in allografted patients with multiple myeloma.

    Kröger, N., Badbaran, A., Lioznov, M., Schwartz, S., Zeschke, S., Hildebrandt, Y., Ayuketang Ayuk, F., Atanackovic, D., Schilling, G., Zabelina, T., Bacher, U., Klyuchnikov, E., Shimoni, A., Nagler, A., Corradini, P., Fehse, B. & Zander, A. R., 2009, In: EXP HEMATOL. 37, 7, p. 791-798 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.

    Bacher, U., Badbaran, A., Fehse, B., Zabelina, T., Zander, A. R. & Kröger, N., 2009, In: EXP HEMATOL. 37, 1, p. 135-142 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.

    Metzner, A., Precht, C., Fehse, B., Fiedler, W., Stocking, C., Günther, A., Mayr, G. W. & Jücker, M., 2009, In: GENE THER. 16, 4, p. 570-573 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Retroviral insertion site analysis in dominant haematopoietic clones.

    Kustikova, O. S., Modlich, U. & Fehse, B., 2009, In: Methods Mol Biol. 506, p. 373-390

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.

    Michaelis, M., Rothweiler, F., Klassert, D., von Deimling, A., Riecken, K., Fehse, B., Kammerer, B., Doerr, H. W. & Cinatl, J., 2009, In: CANCER RES. 69, 2, p. 416-421 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.

    Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Syngenic graft-versus-chronic-myeloid-leukemia-effect?

    Ocheni, S., Schafhausen, P., Bacher, U., Fehse, B. & Kröger, N., 2009, In: CTT-Cell Ther Transpl. 1, 3, p. 66-68 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. 2010
  30. Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells.

    Rothweiler, F., Michaelis, M., Brauer, P., Otte, J., Riecken, K., Fehse, B., Doerr, H. W., Wiese, M., Kreuter, J., Al-Abed, Y., Nicoletti, F. & Cinatl, J., 2010, In: NEOPLASIA. 12, 12, p. 1023-1030 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).

    Stocking, C., Grez, M., Fehse, B., von Laer, D., Itoh, K., Prassolov, V., Nowock, J., Kühlcke, K., Just, U., Schröder, T., Klump, H., Schiedlmeier, B., Grassman, E., Meyer, J., Li, Z., Schambach, A., Modlich, U., Kustikova, O., Galla, M., Jürgen, B., Zander, A. R. & Baum, C., 2010, In: HUM GENE THER. 21, 11, p. 1501-1503 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia.

    Wiedemann, B., Klyuchnikov, E., Kröger, N., Zabelina, T., Stahl, T., Zeschke, S., Badbaran, A., Ayuketang Ayuk, F., Alchalby, H., Wolschke, C., Bokemeyer, C., Fehse, B., Zander, A. R. & Bacher, U., 2010, In: EXP HEMATOL. 38, 12, p. 1261-1271 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Highly efficient lentiviral transduction of phenotypically and genotypically characterized endothelial progenitor cells from adult peripheral blood.

    Stockschlaeder, M., Shardakova, O., Riecken, K., Stoldt, V. R., Fehse, B., Giers, G. & Scharf, R. E., 2010, In: BLOOD COAGUL FIBRIN. 21, 5, p. 464-473 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis.

    Alchalby, H., Badbaran, A., Zabelina, T., Kobbe, G., Hahn, J., Wolff, D., Bornhäuser, M., Christian, T., Baurmann, H., Bethge, W., Hildebrandt, Y., Bacher, U., Fehse, B., Zander, A. R. & Kröger, N., 2010, In: BLOOD. 116, 18, p. 3572-3581 18.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation.

    Vafaizadeh, V., Klemmt, P., Brendel, C., Riecken, K., Doebele, C., Britt, K., Grez, M., Fehse, B., Desriviéres, S. & Groner, B., 2010, In: STEM CELLS. 28, 5, p. 928-938 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Neue Wege der Stammzellforschung: Reprogrammierung von differenzierten Körperzellen

    Beier, HM., Fehse, B., Friedrich, B., Götz, M., Hansmann, I., Hucho, F., Köchy, K., Müller-Röber, B., Rheinberger, HJ., Reich, J., Robpers, HH., Schöler, HR., Schöne-Seifert, B., Sperling, K., Tanner, K., Taupitz, J. & Wobus, AM., 2010, In: J Reprodmed Endokrinol. 7, p. 68-77

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCT.

    Alchalby, H., Badbaran, A., Bock, O., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: BONE MARROW TRANSPL. 45, 9, p. 1404-1407 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. TK.007: A novel, codon-optimized HSVtk(A168H) mutant for suicide gene therapy.

    Preuß, E., Treschow, A., Newrzela, S., Brücher, D., Riecken, K., Felldin, U., Alici, E., Gahrton, G., von Laer, D., Dilber, M. S. & Fehse, B., 2010, In: HUM GENE THER. 21, 8, p. 929-941 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Influence of mannose-binding lectin genotypes and serostatus in allo-SCT: analysis of 131 recipients and donors.

    Neth, O. W., Bacher, U., Das, P., Zabelina, T., Kabisch, H., Kroeger, N., Ayuketang, F. A., Lioznov, M., Waschke, O., Fehse, B., Thiébaut, R., Haston, R. M., Klein, N. & Zander, A. R., 01.01.2010, In: BONE MARROW TRANSPL. 45, 1, p. 13-9 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Minimal residual disease diagnostics in patients with acute myeloid leukemia in the post-transplant period: comparison of peripheral blood and bone marrow analysis.

    Stahl, T., Badbaran, A., Kröger, N., Klyuchnikov, E., Zabelina, T., Zeschke, S., Schafhausen, P., Schultz, W., Asenova, S., Smirnova, A., Wolschke, C., Ayuketang Ayuk, F., Zander, A. R., Fehse, B. & Bacher, U., 01.10.2010, In: LEUKEMIA LYMPHOMA. 51, 10, p. 1837-1843 7 p., 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. 2011
  42. Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.

    Preuß, E., Muik, A., Riecken, K., Otte, J., von Laer, D. & Fehse, B., 2011, In: J MOL MED. 89, 11, p. 1113-1124 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Control of bone formation by the serpentine receptor Frizzled-9.

    Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.

    Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Gene therapy strategies: can we eradicate HIV?

    van Lunzen, J., Fehse, B. & Hauber, J., 2011, In: CURR HIV-AIDS REP. 8, 2, p. 78-84 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Genetic Modifications – Possibilities and Limits of Gene Therapy

    Fehse, B., 2011, Human Nature and Self Design. mentis Verlag Paderborn, p. 113-136 24 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  47. Gentherapie in Deutschland. Eine Einführung

    Domasch, S. & Fehse, B., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 31-40 10 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  48. Minimal residual disease diagnostics and chimerism in the post-transplant period in acute myeloid leukemia.

    Bacher, U., Haferlach, T., Fehse, B., Schnittger, S. & Kröger, N., 2011, In: SCI WORLD J. 11, p. 310-319

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.

    Newrzela, S., Cornils, K., Heinrich, T., Schläger, J., Yi, J-H., Lysenko, O., Kimpel, J., Fehse, B. & Dorothee, V. L., 2011, In: MOL MED. 17, 11-12, p. 1223-1232 11-12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. RGB marking facilitates multicolor clonal cell tracking.

    Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Stand wissenschaftlicher und medizinischer Entwicklungen

    Fehse, B., Baum, C., Schmidt, M. & Kalle, C., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 41-126 86 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  52. Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation

    Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. 2012
  55. Efficient lentiviral transduction and transgene expression in primary human B cells.

    Mock, U., Thiele, R., Uhde, A., Fehse, B. & Horn, S., 2012, In: HUM GENE THER METHOD. 23, 6, p. 408-415 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review