Dr. ID: 36004
Michaela Schweizer
Publications
- 2023
Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism
Loos, M., Klampe, B., Schulze, T., Yin, X., Theofilatos, K., Ulmer, B. M., Schulz, C., Behrens, C. S., van Bergen, T. D., Adami, E., Maatz, H., Schweizer, M., Brodesser, S., Skryabin, B. V., Rozhdestvensky, T. S., Bodbin, S., Stathopoulou, K., Christ, T., Denning, C., Hübner, N., Mayr, M., Cuello, F., Eschenhagen, T. & Hansen, A., 14.11.2023, In: STEM CELL REP. 18, 11, p. 2123-2137 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tetraspanin 15 depletion impairs extracellular vesicle docking at target neurons
Stajano, D., Lombino, F. L., Schweizer, M., Glatzel, M., Saftig, P., Gromova, K. V. & Kneussel, M., 11.09.2023, In: Journal of Extracellular Biology. 2, 9, p. e113Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Short-term dietary changes can result in mucosal and systemic immune depression
Siracusa, F., Schaltenberg, N., Kumar, Y., Lesker, T. R., Steglich, B., Liwinski, T., Cortesi, F., Frommann, L., Diercks, B-P., Bönisch, F., Fischer, A. W., Scognamiglio, P., Pauly, M. J., Casar, C., Cohen, Y., Pelczar, P., Agalioti, T., Delfs, F., Worthmann, A., Wahib, R., Jagemann, B., Mittrücker, H-W., Kretz, O., Guse, A. H., Izbicki, J. R., Lassen, K. G., Strowig, T., Schweizer, M., Villablanca, E. J., Elinav, E., Huber, S., Heeren, J. & Gagliani, N., 09.2023, In: NAT IMMUNOL. 24, 9, p. 1473-1486 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Golgi satellites are essential for polysialylation of NCAM and expression of LTP at distal synapses
Andres-Alonso, M., Borgmeyer, M., Mirzapourdelavar, H., Lormann, J., Klein, K., Schweizer, M., Hoffmeister-Ullerich, S., Oelschlegel, A. M., Dityatev, A. & Kreutz, M. R., 25.07.2023, In: CELL REP. 42, 7, 112692.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
Gromova, K. V., Thies, E., Janiesch, P. C., Lützenkirchen, F. P., Zhu, Y., Stajano, D., Dürst, C. D., Schweizer, M., Konietzny, A., Mikhaylova, M., Gee, C. E. & Kneussel, M., 25.07.2023, In: CELL REP. 42, 7, p. 1-24 112743.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Monoallelic loss of the F-actin-binding protein radixin facilitates startle reactivity and pre-pulse inhibition in mice
Hausrat, T. J., Vogl, C., Neef, J., Schweizer, M., Yee, B. K., Strenzke, N. & Kneussel, M., 28.11.2022, In: FRONT CELL DEV BIOL. 10, 987691.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Endogenous tagging reveals a mid-Golgi localization of the glycosyltransferase-cleaving intramembrane protease SPPL3
Truberg, J., Hobohm, L., Jochimsen, A., Desel, C., Schweizer, M. & Voss, M., 11.2022, In: BBA-MOL CELL RES. 1869, 11, 119345.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
Richards, C. M., Jabs, S., Qiao, W., Varanese, L. D., Schweizer, M., Mosen, P. R., Riley, N. M., Klüssendorf, M., Zengel, J. R., Flynn, R. A., Rustagi, A., Widen, J. C., Peters, C. E., Ooi, Y. S., Xie, X., Shi, P-Y., Bartenschlager, R., Puschnik, A. S., Bogyo, M., Bertozzi, C. R., Blish, C. A., Winter, D., Nagamine, C. M., Braulke, T. & Carette, J. E., 07.10.2022, In: SCIENCE. 378, 6615, eabn5648.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
Krasemann, S., Haferkamp, U., Pfefferle, S., Woo, M. S., Heinrich, F., Schweizer, M., Appelt-Menzel, A., Cubukova, A., Barenberg, J., Leu, J., Hartmann, K., Thies, E., Littau, J. L., Sepulveda-Falla, D., Zhang, L., Ton, K., Liang, Y., Matschke, J., Ricklefs, F., Sauvigny, T., Sperhake, J., Fitzek, A., Gerhartl, A., Brachner, A., Geiger, N., König, E-M., Bodem, J., Franzenburg, S., Franke, A., Moese, S., Müller, F-J., Geisslinger, G., Claussen, C., Kannt, A., Zaliani, A., Gribbon, P., Ondruschka, B., Neuhaus, W., Friese, M. A., Glatzel, M. & Pless, O., 08.02.2022, In: STEM CELL REP. 17, 2, p. 307-320 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart
Bräuninger, H., Stoffers, B., Fitzek, A. D. E., Meißner, K., Aleshcheva, G., Schweizer, M., Weimann, J., Rotter, B., Warnke, S., Edler, C., Braun, F., Roedl, K., Scherschel, K., Escher, F., Kluge, S., Huber, T. B., Ondruschka, B., Schultheiss, H-P., Kirchhof, P., Blankenberg, S., Püschel, K., Westermann, D. & Lindner, D., 29.01.2022, In: CARDIOVASC RES. 118, 2, p. 542-555 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III
Di Lorenzo, G., Westermann, L. M., Schinke, T., Stürznickel, J., Ludwig, N. F., Ammer, L. S., Baranowsky, A., Ahmadi, S., Pourbarkhordariesfandabadi, E., Breyer, S. R., Board, T. N., Foster, A., Mercer, J., Tylee, K., Velho, R. V., Schweizer, M., Renné, T., Braulke, T., Randon, D. N., Sperb-Ludwig, F., de Camargo Pinto, L. L., Moreno, C. A., Cavalcanti, D. P., Amling, M., Kutsche, K., Winter, D., Muschol, N. M., Schwartz, I. V. D., Rolvien, T., Danyukova, T., Schinke, T. & Pohl, S., 12.2021, In: GENET MED. 23, 12, p. 2369-2377 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Wnt1 Promotes Cementum and Alveolar Bone Growth in a Time-Dependent Manner
Nottmeier, C., Liao, N., Simon, A., Decker, M. G., Luther, J., Schweizer, M., Yorgan, T., Kaucka, M., Bockamp, E., Kahl-Nieke, B., Amling, M., Schinke, T., Petersen, J. & Koehne, T., 12.2021, In: J DENT RES. 100, 13, p. 1501-1509 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Linsenmeier, L., Mohammadi, B., Shafiq, M., Frontzek, K., Bär, J., Shrivastava, A. N., Damme, M., Song, F., Schwarz, A., Da Vela, S., Massignan, T., Jung, S., Correia, A., Schmitz, M., Puig, B., Hornemann, S., Zerr, I., Tatzelt, J., Biasini, E., Saftig, P., Schweizer, M., Svergun, D., Amin, L., Mazzola, F., Varani, L., Thapa, S., Gilch, S., Schätzl, H., Harris, D. A., Triller, A., Mikhaylova, M., Aguzzi, A., Altmeppen, H. C. & Glatzel, M., 26.11.2021, In: SCI ADV. 7, 48, p. eabj1826Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV
Vollersen, N., Zhao, W., Rolvien, T., Lange, F., Schmidt, F. N., Sonntag, S., Shmerling, D., von Kroge, S., Stockhausen, K. E., Sharaf, A., Schweizer, M., Karsak, M., Busse, B., Bockamp, E., Semler, O., Amling, M., Oheim, R., Schinke, T. & Yorgan, T. A., 10.11.2021, In: BONE RES. 9, 1, p. 48Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
Borgmeyer, M., Coman, C., Has, C., Schött, H-F., Li, T., Westhoff, P., Cheung, Y. F. H., Hoffmann, N., Yuanxiang, P., Behnisch, T., Gomes, G. M., Dumenieu, M., Schweizer, M., Chocholoušková, M., Holčapek, M., Mikhaylova, M., Kreutz, M. R. & Ahrends, R., 05.10.2021, In: CELL REP. 37, 1, p. 109797Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation
Cuello, F., Knaust, A. E., Saleem, U., Loos, M., Raabe, J., Mosqueira, D., Laufer, S., Schweizer, M., van der Kraak, P., Flenner, F., Ulmer, B. M., Braren, I., Yin, X., Theofilatos, K., Ruiz-Orera, J., Patone, G., Klampe, B., Schulze, T., Piasecki, A., Pinto, Y., Vink, A., Hübner, N., Harding, S., Mayr, M., Denning, C., Eschenhagen, T. & Hansen, A., 07.06.2021, In: EMBO MOL MED. 13, 6, p. e13074Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue
Rhoden, A., Friedrich, F. W., Brandt, T., Raabe, J., Schweizer, M., Meisterknecht, J., Wittig, I., Ulmer, B. M., Klampe, B., Uebeler, J., Piasecki, A., Lorenz, K., Eschenhagen, T., Hansen, A. & Cuello, F., 05.2021, In: REDOX BIOL. 41, p. 101951Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TFEB-deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass, F., Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 05.2021, In: MOL METAB. 47, p. 101173Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate
Mailer, R. K., Allende, M., Heestermans, M., Schweizer, M., Deppermann, C., Frye, M., Pula, G., Odeberg, J., Gelderblom, M., Rose-John, S., Sickmann, A., Blankenberg, S., Huber, T. B., Kubisch, C., Maas, C., Gambaryan, S., Firsov, D., Stavrou, E. X., Butler, L. M. & Renné, T., 11.03.2021, In: BLOOD. 137, 10, p. 1392-1405 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation
Hendrickx, G., Fischer, V., Liedert, A., von Kroge, S., Haffner-Luntzer, M., Brylka, L., Pawlus, E., Schweizer, M., Yorgan, T. A., Baranowsky, A., Rolvien, T., Neven, M., Schumacher, U., Beech, D. J., Amling, M., Ignatius, A. & Schinke, T., 02.2021, In: J BONE MINER RES. 36, 2, p. 369-384 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution
Schlein, C., Fischer, A. W., Sass, F., Worthmann, A., Tödter, K., Jaeckstein, M. Y., Behrens, J., Lynes, M. D., Kiebish, M. A., Narain, N. R., Bussberg, V., Jespersen, N. Z., Nielsen, S., Scheele, C., Schweizer, M., Braren, I., Bartelt, A., Tseng, Y-H., Heeren, J. & Scheja, L., 12.01.2021, In: CELL REP. 34, 2, p. 108624Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuroserpin Is Strongly Expressed in the Developing and Adult Mouse Neocortex but Its Absence Does Not Perturb Cortical Lamination and Synaptic Proteome
Kement, D., Reumann, R., Schostak, K., Voß, H., Douceau, S., Dottermusch, M., Schweizer, M., Schlüter, H., Vivien, D., Glatzel, M. & Galliciotti, G., 2021, In: FRONT NEUROANAT. 15, p. 627896Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Cardiac SARS-CoV-2 infection is associated with distinct transcriptomic changes within the heart
Lindner, D., Bräuninger, H., Stoffers, B., Fitzek, A., Meißner, K., Aleshcheva, G., Schweizer, M., Weimann, J., Rotter, B., Warnke, S., Edler, C., Braun, F., Roedl, K., Scherschel, K., Escher, F., Kluge, S., Huber, T. B., Ondruschka, B., Heinz-Peter-Schultheiss, Kirchhof, P., Blankenberg, S., Püschel, K. & Westermann, D., 22.12.2020, In: medRxiv. p. 2020.12.19.20248542Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma
Westermann, L. M., Fleischhauer, L., Vogel, J., Jenei-Lanzl, Z., Floriano Ludwig, N., Schau, L., Morellini, F., Baranowsky, A., Yorgan, T. A., Di Lorenzo, G., Schweizer, M., de Souza Pinheiro, B., Guarany, N. R., Sperb-Ludwig, F., Visioli, F., Oliveira Silva, T., Soul, J., Hendrickx, G., Wiegert, J. S., Schwartz, I. V. D., Clausen-Schaumann, H., Zaucke, F., Schinke, T., Pohl, S. & Danyukova, T., 18.11.2020, In: DIS MODEL MECH. 13, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An Important Role for DNMT3A-Mediated DNA Methylation in Cardiomyocyte Metabolism and Contractility
Madsen, A., Höppner, G., Krause, J., Hirt, M. N., Laufer, S. D., Schweizer, M., Tan, W. L. W., Mosqueira, D., Anene-Nzelu, C. G., Lim, I., Foo, R. S. Y., Eschenhagen, T. & Stenzig, J., 20.10.2020, In: CIRCULATION. 142, 16, p. 1562-1578 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells is associated with brain metastasis and alters exosome biogenesis
Arnold, J., Schattschneider, J., Blechner, C., Krisp, C., Schlüter, H., Schweizer, M., Nalaskowski, M., Oliveira-Ferrer, L. & Windhorst, S., 30.09.2020, In: J EXP CLIN CANC RES. 39, 1, p. 205Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits
Lopes, A. T., Hausrat, T. J., Heisler, F. F., Gromova, K. V., Lombino, F. L., Fischer, T., Ruschkies, L., Breiden, P., Thies, E., Hermans-Borgmeyer, I., Schweizer, M., Schwarz, J. R., Lohr, C. & Kneussel, M., 31.08.2020, In: PLOS BIOL. 18, 8, p. e3000820Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes
Feyen, D. A. M., McKeithan, W. L., Bruyneel, A. A. N., Spiering, S., Hörmann, L., Ulmer, B., Zhang, H., Briganti, F., Schweizer, M., Hegyi, B., Liao, Z., Pölönen, R-P., Ginsburg, K. S., Lam, C. K., Serrano, R., Wahlquist, C., Kreymerman, A., Vu, M., Amatya, P. L., Behrens, C. S., Ranjbarvaziri, S., Maas, R. G. C., Greenhaw, M., Bernstein, D., Wu, J. C., Bers, D. M., Eschenhagen, T., Metallo, C. M. & Mercola, M., 21.07.2020, In: CELL REP. 32, 3, p. 107925Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nonspecific Expression in Limited Excitatory Cell Populations in Interneuron-Targeting Cre-driver Lines Can Have Large Functional Effects
Müller-Komorowska, D., Opitz, T., Elzoheiry, S., Schweizer, M., Ambrad Giovannetti, E. & Beck, H., 27.04.2020, In: FRONT NEURAL CIRCUIT. 14, p. 16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enzyme replacement therapy in mice lacking arylsulfatase B targets bone remodeling cells, but not chondrocytes
Hendrickx, G., Danyukova, T., Baranowsky, A., Rolvien, T., Angermann, A., Schweizer, M., Keller, J., Schröder, J., Meyer-Schwesinger, C., Muschol, N., Paganini, C., Rossi, A., Amling, M., Pohl, S. & Schinke, T., 27.03.2020, In: HUM MOL GENET. 29, 5, p. 803-816 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin
Hermann, M., Reumann, R., Schostak, K., Kement, D., Gelderblom, M., Bernreuther, C., Frischknecht, R., Schipanski, A., Marik, S., Krasemann, S., Sepulveda-Falla, D., Schweizer, M., Magnus, T., Glatzel, M. & Galliciotti, G., 01.2020, In: MOL CELL NEUROSCI. 102, p. 103420Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals
Andres-Alonso, M., Ammar, M. R., Butnaru, I., Gomes, G. M., Acuña Sanhueza, G., Raman, R., Yuanxiang, P., Borgmeyer, M., Lopez-Rojas, J., Raza, S. A., Brice, N., Hausrat, T. J., Macharadze, T., Diaz-Gonzalez, S., Carlton, M., Failla, A. V., Stork, O., Schweizer, M., Gundelfinger, E. D., Kneussel, M., Spilker, C., Karpova, A. & Kreutz, M. R., 29.11.2019, In: NAT COMMUN. 10, 1, p. 5448Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
Richter, M., Murtaza, N., Scharrenberg, R., White, S. H., Johanns, O., Walker, S., Yuen, R. K. C., Schwanke, B., Bedürftig, B., Henis, M., Scharf, S., Kraus, V., Dörk, R., Hellmann, J., Lindenmaier, Z., Ellegood, J., Hartung, H., Kwan, V., Sedlacik, J., Fiehler, J., Schweizer, M., Lerch, J. P., Hanganu-Opatz, I. L., Morellini, F., Scherer, S. W., Singh, K. K. & Calderon de Anda, F., 09.2019, In: MOL PSYCHIATR. 24, 9, p. 1329-1350 22 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Maintenance of cell type-specific connectivity and circuit function requires Tao kinase
Tenedini, F. M., Sáez González, M., Hu, C., Pedersen, L. H., Petruzzi, M. M., Spitzweck, B., Wang, D., Richter, M., Petersen, M., Szpotowicz, E., Schweizer, M., Sigrist, S. J., Calderon de Anda, F. & Soba, P., 05.08.2019, In: NAT COMMUN. 10, 1, p. 3506Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression
Wagner, W., Lippmann, K., Heisler, F. F., Gromova, K. V., Lombino, F. L., Roesler, M. K., Pechmann, Y., Hornig, S., Schweizer, M., Polo, S., Schwarz, J. R., Eilers, J. & Kneussel, M., 02.07.2019, In: CELL REP. 28, 1, p. 11-20.e9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal proteome analysis reveals that CLN3-defective cells have multiple enzyme deficiencies associated with changes in intracellular trafficking
Schmidtke, C., Tiede, S., Thelen, M., Käkelä, R., Jabs, S., Makrypidi, G., Sylvester, M., Schweizer, M., Braren, I., Brocke-Ahmadinejad, N., Cotman, S. L., Schulz, A., Gieselmann, V. & Braulke, T., 14.06.2019, In: J BIOL CHEM. 294, 24, p. 9592-9604 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks
Reinicke, A. T., Laban, K., Sachs, M., Kraus, V., Walden, M., Damme, M., Sachs, W., Reichelt, J., Schweizer, M., Janiesch, P. C., Duncan, K. E., Saftig, P., Rinschen, M. M., Morellini, F. & Meyer-Schwesinger, C., 16.04.2019, In: P NATL ACAD SCI USA. 116, 16, p. 7963-7972 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice
Schob, C., Morellini, F., Ohana, O., Bakota, L., Hrynchak, M. V., Brandt, R., Brockmann, M. D., Cichon, N., Hartung, H., Hanganu-Opatz, I. L., Kraus, V., Scharf, S., Herrmans-Borgmeyer, I., Schweizer, M., Kuhl, D., Wöhr, M., Vörckel, K. J., Calzada-Wack, J., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Garner, C. C., Kreienkamp, H-J. & Kindler, S., 16.01.2019, In: TRANSL PSYCHIAT. 9, 1, p. 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization
Roesler, M. K., Lombino, F. L., Freitag, S., Schweizer, M., Hermans-Borgmeyer, I., Schwarz, J. R., Kneussel, M. & Wagner, W., 2019, In: FRONT CELL NEUROSCI. 13, p. 330Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Visualization of translocons in Yersinia type III protein secretion machines during host cell infection
Nauth, T., Huschka, F., Schweizer, M., Bosse, J. B., Diepold, A., Failla, A. V., Steffen, A., Stradal, T., Wolters, M. & Aepfelbacher, M., 26.12.2018, In: PLOS PATHOG. 14, 12, p. e1007527Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Lysosomal Protein Arylsulfatase B Is a Key Enzyme Involved in Skeletal Turnover
Pohl, S., Angermann, A., Jeschke, A., Hendrickx, G., Yorgan, T. A., Makrypidi-Fraune, G., Steigert, A., Kuehn, S. C., Rolvien, T., Schweizer, M., Koehne, T., Neven, M., Winter, O., Velho, R. V., Albers, J., Streichert, T., Pestka, J. M., Baldauf, C., Breyer, S., Stuecker, R., Muschol, N., Cox, T. M., Saftig, P., Paganini, C., Rossi, A., Amling, M., Braulke, T. & Schinke, T., 12.2018, In: J BONE MINER RES. 33, 12, p. 2186-2201 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand
Luther, J., Yorgan, T. A., Rolvien, T., Ulsamer, L., Koehne, T., Liao, N., Keller, D., Vollersen, N., Teufel, S., Neven, M., Peters, S., Schweizer, M., Trumpp, A., Rosigkeit, S., Bockamp, E., Mundlos, S., Kornak, U., Oheim, R., Amling, M., Schinke, T. & David, J-P., 07.11.2018, In: SCI TRANSL MED. 10, 466, p. eaau7137Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Muskelin Coordinates PrP Lysosome versus Exosome Targeting and Impacts Prion Disease Progression
Heisler, F. F., Pechmann, Y., Wieser, I., Altmeppen, H. C., Veenendaal, L., Muhia, M., Schweizer, M., Glatzel, M., Krasemann, S. & Kneussel, M., 19.09.2018, In: NEURON. 99, 6, p. 1155-1169.e9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease-Linked Glutarylation Impairs Function and Interactions of Mitochondrial Proteins and Contributes to Mitochondrial Heterogeneity
Schmiesing, J., Storch, S., Dörfler, A-C., Schweizer, M., Makrypidi-Fraune, G., Thelen, M., Sylvester, M., Gieselmann, V., Meyer-Schwesinger, C., Koch-Nolte, F., Tidow, H., Mühlhausen, C., Waheed, A., Sly, W. S. & Braulke, T., 11.09.2018, In: CELL REP. 24, 11, p. 2946-2956 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15
Seipold, L., Altmeppen, H., Koudelka, T., Tholey, A., Kasparek, P., Sedlacek, R., Schweizer, M., Bär, J., Mikhaylova, M., Glatzel, M. & Saftig, P., 09.2018, In: CELL MOL LIFE SCI. 75, 17, p. 3251-3267 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells
Di Lorenzo, G., Velho, R. V., Winter, D., Thelen, M., Ahmadi, S., Schweizer, M., De Pace, R., Cornils, K., Yorgan, T. A., Grüb, S., Hermans-Borgmeyer, I., Schinke, T., Müller-Loennies, S., Braulke, T. & Pohl, S., 08.2018, In: MOL CELL PROTEOMICS. 17, 8, p. 1612-1626 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes
Gonzalez, A. C., Schweizer, M., Jagdmann, S., Bernreuther, C., Reinheckel, T., Saftig, P. & Damme, M., 23.01.2018, In: CELL REP. 22, 4, p. 1040-1053 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Site-1 protease and lysosomal homeostasis
Velho, R. V., De Pace, R., Klünder, S., Di Lorenzo, G., Schweizer, M., Braulke, T. & Pohl, S., 11.2017, In: BBA-MOL CELL RES. 1864, 11 Pt B, p. 2162-2168Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Sensory integration and neuromodulatory feedback facilitate Drosophila mechanonociceptive behavior
Hu, C., Petersen, M., Hoyer, N., Spitzweck, B., Tenedini, F., Wang, D., Gruschka, A., Burchardt, L. S., Szpotowicz, E., Schweizer, M., Guntur, A. R., Yang, C-H. & Soba, P., 08.2017, In: NAT NEUROSCI. 20, 8, p. 1085-1095Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Influence of MHC Class II on B Cell Defects Induced by Invariant Chain/CD74 N-Terminal Fragments
Schneppenheim, J., Loock, A-C., Hüttl, S., Schweizer, M., Lüllmann-Rauch, R., Oberg, H-H., Arnold, P., Lehmann, C. H. K., Dudziak, D., Kabelitz, D., Lucius, R., Lennon-Duménil, A-M., Saftig, P. & Schröder, B., 01.07.2017, In: J IMMUNOL. 199, 1, p. 172-185 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Posttranslational modification impact on the mechanism by which amyloid-β induces synaptic dysfunction
Grochowska, K. M., Yuanxiang, P., Bär, J., Raman, R., Brugal, G., Sahu, G., Schweizer, M., Bikbaev, A., Schilling, S., Demuth, H-U. & Kreutz, M. R., 06.2017, In: EMBO REP. 18, 6, p. 962-981Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease
Segal-Salto, M., Hansson, K., Sapir, T., Kaplan, A., Levy, T., Schweizer, M., Frotscher, M., James, P. & Reiner, O., 01.05.2017, In: HUM MOL GENET. 26, 9, p. 1678Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative Proteome Analysis of Mouse Liver Lysosomes Provides Evidence for Mannose 6-phosphate-independent Targeting Mechanisms of Acid Hydrolases in Mucolipidosis II
Markmann, S., Krambeck, S., Hughes, C. J., Mirzaian, M., Aerts, J. M. F. G., Saftig, P., Schweizer, M., Vissers, J. P. C., Braulke, T. & Damme, M., 03.2017, In: MOL CELL PROTEOMICS. 16, 3, p. 438-450 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease-causing mutations affecting surface residues of mitochondrial glutaryl-CoA dehydrogenase impair stability, heteromeric complex formation, and mitochondria architecture
Schmiesing, J., Lohmöller, B., Schweizer, M., Tidow, H., Gersting, S. W., Muntau, A. C., Braulke, T. & Mühlhausen, C., 01.02.2017, In: HUM MOL GENET. 26, 3, p. 538-551Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Formation of Calcified Nanospherites during Micropetrosis Represents a Unique Mineralization Mechanism in Aged Human Bone
Milovanovic, P., Zimmermann, E. A., vom Scheidt, A., Hoffmann, B., Sarau, G., Yorgan, T., Schweizer, M., Amling, M., Christiansen, S. & Busse, B., 18.01.2017, In: SMALL. 13, 3, p. n/a-n/aResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Mannose 6-phosphate-dependent targeting of lysosomal enzymes is required for normal craniofacial and dental development
Koehne, T., Markmann, S., Schweizer, M., Muschol, N., Friedrich, R. E., Hagel, C., Glatzel, M., Kahl-Nieke, B., Amling, M., Schinke, T. & Braulke, T., 09.2016, In: BBA-MOL BASIS DIS. 1862, 9, p. 1570–1580Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal Stromal/Stem Cells Do Not Ameliorate Experimental Autoimmune Encephalomyelitis and Are Not Detectable in the Central Nervous System of Transplanted Mice
Abramowski, P., Krasemann, S., Ernst, T., Lange, C., Ittrich, H., Schweizer, M., Zander, A. R., Martin, R. & Fehse, B., 01.08.2016, In: STEM CELLS DEV. 25, 15, p. 1134-48Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory
Muhia, M., Thies, E., Labonté, D., Ghiretti, A. E., Gromova, K. V., Xompero, F., Lappe-Siefke, C., Hermans-Borgmeyer, I., Kuhl, D., Schweizer, M., Ohana, O., Schwarz, J., Holzbaur, E. L. F. & Kneussel, M., 03.05.2016, In: CELL REP. 15, 5, p. 968-77 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rsk2, the kinase in Coffin-Lowry syndrome controls cementum formation
Koehne, T., Jeschke, A., Petermann, F., Seitz, S., Neven, M., Peters, S., Luther, J., Schweizer, M., Schinke, T., Kahl-Nieke, B., Amling, M. & David, J-P., 29.02.2016, In: J DENT RES. 95, 7, p. 752-760Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal dysfunction and impaired autophagy in a novel mouse model deficient for the lysosomal membrane protein Cln7
Brandenstein, L., Schweizer, M., Sedlacik, J., Fiehler, J. & Storch, S., 15.02.2016, In: HUM MOL GENET. 25, 4, p. 777-91Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
Kuhn, P-H., Colombo, A. V., Schusser, B., Dreymueller, D., Wetzel, S., Schepers, U., Herber, J., Ludwig, A., Kremmer, E., Montag, D., Müller, U., Schweizer, M., Saftig, P., Bräse, S. & Lichtenthaler, S. F., 23.01.2016, In: ELIFE. 5, p. e12748Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inositol-1,4,5-trisphosphate-3-kinase-A controls morphology of hippocampal dendritic spines
Köster, J-D., Leggewie, B., Blechner, C., Brandt, N., Fester, L., Rune, G., Schweizer, M., Kindler, S. & Windhorst, S., 01.2016, In: CELL SIGNAL. 28, 1, p. 83-90 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I
Kühn, S. C., Koehne, T., Cornils, K., Markmann, S., Riedel, C., Pestka, J. M., Schweizer, M., Baldauf, C., Yorgan, T. A., Krause, M., Keller, J., Neven, M., Breyer, S., Stücker, R., Muschol, N., Busse, B., Braulke, T., Fehse, B., Amling, M. & Schinke, T., 15.12.2015, In: HUM MOL GENET. 24, 24, p. 7075-7086Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells
Jeschke, A., Catala-Lehnen, P., Sieber, S., Bickert, T., Schweizer, M., Koehne, T., Wintges, K., Marshall, R. P., Mautner, A., Duchstein, L., Otto, B., Horst, A. K., Amling, M., Kreienkamp, H-J. & Schinke, T., 15.10.2015, In: J IMMUNOL. 195, 8, p. 3675-84 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical fot B Cell Receptor Signaling in Transitional B Cells.
Hüttl, S., Kläsener, K., Schweizer, M., Schneppenheim, J., Oberg, H-H., Kabelitz, D., Reth, M., Saftig, P. & Schröder, B., 15.08.2015, In: J IMMUNOL. 195 , 4, p. 1548-1563Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biological Relevance and Therapeutic Potential of the Hypusine Modification System
Pallmann, N., Braig, M., Sievert, H., Preukschas, M., Hermans-Borgmeyer, I., Schweizer, M., Nagel, C. H., Neumann, M., Wild, P., Haralambieva, E., Hagel, C., Bokemeyer, C., Hauber, J. & Balabanov, S., 02.06.2015, In: J BIOL CHEM. 290, 30, p. 18343-18360Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lrp1/LDL receptor play critical roles in mannose 6-phosphate-independent lysosomal enzyme targeting
Markmann, S., Thelen, M., Cornils, K., Schweizer, M., Brocke-Ahmadinejad, N., Willnow, T., Heeren, J., Gieselmann, V., Braulke, T. & Kollmann, K., 18.03.2015, In: TRAFFIC.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease
Rothaug, M., Stroobants, S., Schweizer, M., Peters, J., Zunke, F., Allerding, M., D Hooge, R., Saftig, P. & Blanz, J., 31.01.2015, In: ACTA NEUROPATHOL COM. 3, 1, p. 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mannose 6 phosphorylation of lysosomal enzymes controls B cell functions
Otomo, T., Schweizer, M., Kollmann, K., Schumacher, V., Muschol, N., Tolosa, E., Mittrücker, H-W. & Braulke, T., 19.01.2015, In: J CELL BIOL. 208, 2, p. 171-80 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance
Rothaug, M., Zunke, F., Mazzulli, J. R., Schweizer, M., Altmeppen, H., Lüllmann-Rauch, R., Kallemeijn, W. W., Gaspar, P., Aerts, J. M., Glatzel, M., Saftig, P., Krainc, D., Schwake, M. & Blanz, J., 28.10.2014, In: P NATL ACAD SCI USA. 111, 43, p. 15573-8 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A spastic paraplegia mouse model reveals REEP1-dependent ER shaping
Beetz, C., Koch, N., Khundadze, M., Zimmer, G., Nietzsche, S., Hertel, N., Huebner, A-K., Mumtaz, R., Schweizer, M., Dirren, E., Karle, K. N., Irintchev, A., Alvarez, V., Redies, C., Westermann, M., Kurth, I., Deufel, T., Kessels, M. M., Qualmann, B. & Hübner, C. A., 02.06.2014, In: J CLIN INVEST. 124, 6, p. 2809Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
A novel mouse model for inhibition of DOHH mediated hypusine modification reveals crucial function for embryonic development, proliferation and oncogenic transformation
Sievert, H., Pällmann, N., Miller, K. K., Hermans-Borgmeyer, I., Venz, S., Sendoel, A., Preukschas, M., Schweizer, M., Böttcher, S., Janiesch, P. C., Streichert, T., Walther, R., Hengartner, M. O., Manz, M. G., Brümmendorf, T. H., Bokemeyer, C., Balabanov, M., Hauber, J., Duncan, K. E. & Balabanov, S., 15.05.2014, In: DIS MODEL MECH.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease
Damme, M., Brandenstein, L., Fehr, S., Jankowiak, W., Bartsch, U., Schweizer, M., Hermans-Borgmeyer, I. & Storch, S., 01.05.2014, In: NEUROBIOL DIS. 65, p. 12-24 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GRIP1 interlinks N-cadherin and AMPA receptors at vesicles to promote combined cargo transport into dendrites
Heisler, F. F., Lee, H. K., Gromova, K. V., Pechmann, Y., Schurek, B., Ruschkies, L., Schroeder, M., Schweizer, M. & Kneussel, M., 2014, In: P NATL ACAD SCI USA. 111, 13, p. 5030-5 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
α2δ3 is essential for normal structure and function of auditory nerve synapses and is a novel candidate for auditory processing disorders
Kurt, S., Zuccotti, A., Pirone, A., Rüttiger, L., Pilz, P., Brown, D. H., Franz, C., Schweizer, M., Rust, M. B., Rübsamen, R., Friauf, E., Knipper, M. & Engel, J., 2014, In: J NEUROSCI. 34, 2, p. 434-45 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II
Kollmann, K., Pestka, J-M., Kühn, S. C., Schöne, E., Schweizer, M., Karkmann, K., Otomo, T., Catala-Lehnen, P., Failla, A. V., Marshall, R. P., Krause, M., Santer, R., Amling, M., Braulke, T. & Schinke, T., 01.12.2013, In: EMBO MOL MED. 5, 12, p. 1871-86 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Acute renal proximal tubule alterations during induced metabolic crises in a mouse model of glutaric aciduria type 1
Thies, B., Meyer-Schwesinger, C., Lamp, J., Schweizer, M., Koeller, D. M., Ullrich, K., Braulke, T. & Mühlhausen, C., 01.10.2013, In: BBA-MOL BASIS DIS. 1832, 10, p. 1463-72 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)
Wintges, K., Beil, F. T., Albers, J., Jeschke, A., Schweizer, M., Claass, B., Tiegs, G., Amling, M. & Schinke, T., 01.10.2013, In: J BONE MINER RES. 28, 10, p. 2070-80 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ultrastructural analysis of neuronal and non-neuronal lysosomal storage in mucolipidosis type II knock-in mice
Schweizer, M., Markmann, S., Braulke, T. & Kollmann, K., 01.10.2013, In: ULTRASTRUCT PATHOL. 37, 5, p. 366-72 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions
Prox, J., Bernreuther, C., Altmeppen, H., Grendel, J., Glatzel, M., D'Hooge, R., Stroobants, S., Ahmed, T., Balschun, D., Willem, M., Lammich, S., Isbrandt, D., Schweizer, M., Horré, K., De Strooper, B. & Saftig, P., 07.08.2013, In: J NEUROSCI. 33, 32, p. 12915-28, 12928aResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel interaction between aging and ER overload in a protein conformational dementia
Schipanski, A., Lange, S., Segref, A., Gutschmidt, A., Lomas, D. A., Miranda, E., Schweizer, M., Hoppe, T. & Glatzel, M., 01.03.2013, In: GENETICS. 193, 3, p. 865-76 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neurons
Zivraj, K. H., Rehbein, M., Ölschläger-Schütt, J., Schob, C., Falley, K., Buck, F., Schweizer, M., Schepis, A., Kremmer, E., Richter, D., Kreienkamp, H-J. & Kindler, S., 01.03.2013, In: J NEUROCHEM. 124, 5, p. 670-84 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma
Grapp, M., Wrede, A., Schweizer, M., Hüwel, S., Galla, H-J., Snaidero, N., Simons, M., Bückers, J., Low, P. S., Urlaub, H., Gärtner, J. & Steinfeld, R., 01.01.2013, In: NAT COMMUN. 4, p. 2123Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate
Helmis, C., Blechner, C., Lin, H., Schweizer, M., Mayr, G. W., Nielsen, P. & Windhorst, S., 01.01.2013, In: BIOSCIENCE REP. 33, 5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis.
Thelen, M., Damme, M., Daμμe, M., Schweizer, M., Hagel, C., Wong, A. M. S., Cooper, J. D., Braulke, T. & Galliciotti, G., 2012, In: PLOS ONE. 7, 4, p. 35493 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High expression of disease-related Cln6 in the cerebral cortex, purkinje cells, dentate gyrus, and hippocampal ca1 neurons.
Thelen, M., Fehr, S., Schweizer, M., Braulke, T. & Galliciotti, G., 2012, In: J NEUROSCI RES. 90, 3, p. 568-574 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice.
Kollmann, K., Damme, M., Markmann, S., Morelle, W., Schweizer, M., Hermans-Borgmeyer, I., Röchert, A. K., Pohl, S., Lübke, T., Michalski, J-C., Käkelä, R., Walkley, S. U. & Braulke, T., 2012, In: BRAIN. 135, Pt 9, p. 2661-2675 Pt 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
M-phase phosphoprotein 11 is a highly immunogenic tumor antigen in patients with acute myeloid leukemia.
Siegel, S., Wirth, S., Schweizer, M., Schmitz, N. & Zeis, M., 2012, In: ACTA HAEMATOL-BASEL. 127, 4, p. 193-197 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
A key enzyme in the biogenesis of lysosomes is a protease that regulates cholesterol metabolism.
Marschner, K., Kollmann, K., Schweizer, M., Braulke, T. & Pohl, S., 2011, In: SCIENCE. 333, 6038, p. 87-90 6038.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein, S., Müller, V., Köhler, N., Wikman, H., Krenkel, S., Streichert, T., Schweizer, M., Riethdorf, S., Assmann, V., Henningsen, M., Beck, K., Issa, R., Jänicke, F., Pantel, K. & Milde-Langosch, K., 2011, In: BREAST CANCER RES TR. 129, 2, p. 347-360 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired stria vascularis integrity upon loss of E-cadherin in basal cells.
Trowe, M-O., Maier, H., Petry, M., Schweizer, M., Schuster-Gossler, K. & Kispert, A., 2011, In: DEV BIOL. 359, 1, p. 95-107 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
Heisler, F., Löbrich, S., Pechmann, Y., Maier, N., Zivkovic, A. R., Tokito, M., Hausrat, T., Schweizer, M., Bähring, R., Holzbaur, E. L. F., Schmitz, D. & Kneussel, M., 2011, In: NEURON. 70, 1, p. 66-81 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Synapsin I is an oligomannose-carrying glycoprotein, acts as an oligomannose-binding lectin, and promotes neurite outgrowth and neuronal survival when released via glia-derived exosomes.
Wang, S., Cesca, F., Loers, G., Schweizer, M., Buck, F., Benfenati, F., Schachner, M. & Kleene, R., 2011, In: J NEUROSCI. 31, 20, p. 7275-7290 20.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Neuroligin 1 is dynamically exchanged at postsynaptic sites.
Schapitz, I., Behrend, B., Pechmann, Y., Lappe-Siefke, C., Kneussel, S. J., Wallace, K. E., Stempel, A. V., Buck, F., Grant, S. G. N., Schweizer, M., Schmitz, D., Schwarz, J., Holzbaur, E. L. F. & Kneussel, M., 2010, In: J NEUROSCI. 30, 38, p. 12733-12744 38.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Erg K+ currents modulate excitability in mouse mitral/tufted neurons.
Hirdes, W., Napp, N., Wulfsen, I., Schweizer, M., Schwarz, J. & Bauer, C. K., 2009, In: PFLUG ARCH EUR J PHY. 459, 1, p. 55-70 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7.
Wartosch, L., Fuhrmann, J. C., Schweizer, M., Stauber, T. & Jentsch, T. J., 2009, In: FASEB J. 23, 12, p. 4056-4068 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice.
Lappe-Siefke, C., Löbrich, S., Hevers, W., Waidmann, O. B., Schweizer, M., Fehr, S., Fritschy, J-M., Dikic, I., Eilers, J., Wilson, S. M. & Kneussel, M., 2009, In: PLOS GENET. 5, 9, p. 1000631 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Sawallisch, C., Berhörster, K., Disanza, A., Mantoani, S., Kintscher, M., Stoenica, L., Dityatev, A., Sieber, S., Kindler, S., Morellini, F., Schweizer, M., Boeckers, T. M., Korte, M., Scita, G. & Kreienkamp, H-J., 2009, In: J BIOL CHEM. 284, 14, p. 9225-9236 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes.
Trowe, M-O., Maier, H., Schweizer, M. & Kispert, A., 2008, In: DEVELOPMENT. 135, 9, p. 1725-1734 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability.
Jacobs, S., Ruusuvuori, E., Sipilä, S. T., Haapanen, A., Damkier, H. H., Kurth, I., Hentschke, M., Schweizer, M., Rudhard, Y., Laatikainen, L. M., Tyynelä, J., Praetorius, J., Voipio, J. & Hübner, C., 2008, In: P NATL ACAD SCI USA. 105, 1, p. 311-316 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Autophagic cell death induced by TrkA receptor activation in human glioblastoma cells.
Hansen, K., Wagner, B., Hamel, W., Schweizer, M., Haag, F., Westphal, M. & Lamszus, K., 2007, In: J NEUROCHEM. 103, 1, p. 259-275 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cilengitide inhibits proliferation and differentiation of human endothelial progenitor cells in vitro.
Loges, S., Butzal, M., Wellbrock, J., Schweizer, M., Fischer, U., Bokemeyer, C., Hossfeld, D. K., Schuch, G. & Fiedler, W., 2007, In: BIOCHEM BIOPH RES CO. 357, 4, p. 1016-1020 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leukoencephalopathy upon disruption of the chloride channel ClC-2.
Blanz, J., Schweizer, M., Auberson, M., Maier, H., Münscher, A., Hübner, C. & Jentsch, T. J., 2007, In: J NEUROSCI. 27, 24, p. 6581-6589 24.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function.
Kurth, I., Thompson, D. A., Rüther, K., Feathers, K. L., Chrispell, J. D., Schroth, J., McHenry, C. L., Schweizer, M., Skosyrski, S., Gal, A. & Hübner, C., 2007, In: MOL CELL BIOL. 27, 4, p. 1370-1379 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review