Prof. Dr.rer.nat. ID: 45614
Ileana L. Hanganu-Opatz
Publications
- SCORING: Journal article › Research › Peer-reviewed
Activation of glycine receptors modulates spontaneous epileptiform activity in the immature rat hippocampus
Chen, R., Okabe, A., Sun, H., Sharopov, S., Hanganu-Opatz, I. L., Kolbaev, S. N., Fukuda, A., Luhmann, H. J. & Kilb, W., 15.05.2014, In: J PHYSIOL-LONDON. 592, Pt 10, p. 2153-68 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A developmental increase of inhibition promotes the emergence of hippocampal ripples
Pochinok, I., Stöber, T. M., Triesch, J., Chini, M. & Hanganu-Opatz, I. L., 25.01.2024, In: NAT COMMUN. 15, 1, p. 738Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
Richter, M., Murtaza, N., Scharrenberg, R., White, S. H., Johanns, O., Walker, S., Yuen, R. K. C., Schwanke, B., Bedürftig, B., Henis, M., Scharf, S., Kraus, V., Dörk, R., Hellmann, J., Lindenmaier, Z., Ellegood, J., Hartung, H., Kwan, V., Sedlacik, J., Fiehler, J., Schweizer, M., Lerch, J. P., Hanganu-Opatz, I. L., Morellini, F., Scherer, S. W., Singh, K. K. & Calderon de Anda, F., 09.2019, In: MOL PSYCHIATR. 24, 9, p. 1329-1350 22 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation
Yang, W., Chini, M., Pöpplau, J. A., Formozov, A., Dieter, A., Piechocinski, P., Rais, C., Morellini, F., Sporns, O., Hanganu-Opatz, I. L. & Wiegert, J. S., 01.04.2021, In: PLOS BIOL. 19, 4, p. e3001146Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An increase of inhibition drives the developmental decorrelation of neural activity
Chini, M., Pfeffer, T. & Hanganu-Opatz, I., 17.08.2022, In: ELIFE. 11, e78811.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice
Bitzenhofer, S. H., Pöpplau, J. A., Chini, M., Marquardt, A. & Hanganu-Opatz, I. L., 21.04.2021, In: NEURON. 109, 8, p. 1350-1364.e6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Between molecules and experience: role of early patterns of coordinated activity for the development of cortical maps and sensory abilities.
Hanganu-Opatz, I. & Ileana, L., 2010, In: BRAIN RES REV. 64, 1, p. 160-176 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blood pressure pulsations modulate central neuronal activity via mechanosensitive ion channels
Jammal Salameh, L., Bitzenhofer, S. H., Hanganu-Opatz, I. L., Dutschmann, M. & Egger, V., 02.02.2024, In: SCIENCE. 383, 6682, p. eadk8511Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bursting mitral cells time the oscillatory coupling between olfactory bulb and entorhinal networks in neonatal mice
Kostka, J. K., Gretenkord, S., Spehr, M. & Hanganu-Opatz, I. L., 12.2020, In: J PHYSIOL-LONDON. 598, 24, p. 5753-5769 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcium imaging and electrophysiology of hippocampal activity under anesthesia and natural sleep in mice
Formozov, A., Chini, M., Dieter, A., Yang, W., Pöpplau, J. A., Hanganu-Opatz, I. L. & Wiegert, J. S., 29.03.2022, In: SCI DATA. 9, 1, p. 1-11 113.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cholinergic control in developing prefrontal-hippocampal networks.
Janiesch, P. C., Krüger, H-S., Pöschel, B. & Hanganu-Opatz, I., 2012, In: J NEUROSCI. 31, 49, p. 17955-17970 49.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice
Schob, C., Morellini, F., Ohana, O., Bakota, L., Hrynchak, M. V., Brandt, R., Brockmann, M. D., Cichon, N., Hartung, H., Hanganu-Opatz, I. L., Kraus, V., Scharf, S., Herrmans-Borgmeyer, I., Schweizer, M., Kuhl, D., Wöhr, M., Vörckel, K. J., Calzada-Wack, J., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Garner, C. C., Kreienkamp, H-J. & Kindler, S., 16.01.2019, In: TRANSL PSYCHIAT. 9, 1, p. 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Coordinated electrical activity in the olfactory bulb gates the oscillatory entrainment of entorhinal networks in neonatal mice
Gretenkord, S., Kostka, J. K., Hartung, H., Watznauer, K., Fleck, D., Minier-Toribio, A., Spehr, M. & Hanganu-Opatz, I. L., 01.2019, In: PLOS BIOL. 17, 1, p. e2006994Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Coupled oscillations mediate directed interactions between prefrontal cortex and hippocampus of the neonatal rat.
Brockmann, M. D., Pöschel, B., Cichon, N. & Hanganu-Opatz, I., 2011, In: NEURON. 71, 2, p. 332-347 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Developmental decrease of entorhinal-hippocampal communication in immune-challenged DISC1 knockdown mice
Xu, X., Song, L., Kringel, R. & Hanganu-Opatz, I. L., 23.11.2021, In: NAT COMMUN. 12, 1, 6810.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Developmental dysfunction of prefrontal-hippocampal networks in mouse models of mental illness
Oberlander, V. C., Xu, X., Chini, M. & Hanganu-Opatz, I. L., 09.2019, In: EUR J NEUROSCI. 50, 6, p. 3072-3084 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Early-life stress impairs recognition memory and perturbs the functional maturation of prefrontal-hippocampal-perirhinal networks
Reincke, S. AJ. & Hanganu-Opatz, I. L., 07.02.2017, In: SCI REP-UK. 7, p. 42042Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Event-related potential evidence for a dynamic (re-)weighting of somatotopic and external coordinates of touch during visual-tactile interactions
Ley, P., Steinberg, U., Hanganu-Opatz, I. L. & Röder, B., 05.2015, In: EUR J NEUROSCI. 41, 11, p. 1466-74 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
From Shortage to Surge: A Developmental Switch in Hippocampal-Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders
Hartung, H., Cichon, N., De Feo, V., Riemann, S., Schildt, S., Lindemann, C., Mulert, C., Gogos, J. A. & Hanganu-Opatz, I. L., 10.2016, In: CEREB CORTEX. 26, 11, p. 4265-4281Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gamma activity accelerates during prefrontal development
Bitzenhofer, S. H., Pöpplau, J. A. & Hanganu-Opatz, I., 18.11.2020, In: ELIFE. 9, p. e56795Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Generation and propagation of bursts of activity in the developing basal ganglia
Klavinskis-Whiting, S., Bitzenhofer, S., Hanganu-Opatz, I. & Ellender, T., 09.10.2023, In: CEREB CORTEX. 33, 20, p. 10595-10613 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Glutamatergic deficit and schizophrenia-like negative symptoms: new evidence from ketamine-induced mismatch negativity alterations in healthy male humans
Thiebes, S., Leicht, G., Curic, S., Steinmann, S., Polomac, N., Andreou, C., Eichler, I., Eichler, L., Zöllner, C., Gallinat, J., Hanganu-Opatz, I. & Mulert, C., 06.2017, In: J PSYCHIATR NEUROSCI. 42, 4, p. 273-283 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Glutamatergic drive along the septo-temporal axis of hippocampus boosts prelimbic oscillations in the neonatal mouse
Ahlbeck, J., Song, L., Chini, M., Bitzenhofer, S. H. & Hanganu-Opatz, I. L., 10.04.2018, In: ELIFE. 7, p. e33158Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypoxia-ischemia disrupts directed interactions within neonatal prefrontal-hippocampal networks
Brockmann, M. D., Kukovic, M., Schönfeld, M., Sedlacik, J. & Hanganu-Opatz, I. L., 01.01.2013, In: PLOS ONE. 8, 12, p. e83074Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased Resting-State Gamma-Band Connectivity in First-Episode Schizophrenia
Andreou, C., Nolte, G., Leicht, G., Polomac, N., Hanganu-Opatz, I. L., Lambert, M., Engel, A. K. & Mulert, C., 07.2015, In: SCHIZOPHRENIA BULL. 41, 4, p. 930-939Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interdependent Conductances Drive Infraslow Intrinsic Rhythmogenesis in a Subset of Accessory Olfactory Bulb Projection Neurons
Gorin, M., Tsitoura, C., Kahan, A., Watznauer, K., Drose, D. R., Arts, M., Mathar, R., O'Connor, S., Hanganu-Opatz, I. L., Ben-Shaul, Y. & Spehr, M., 16.03.2016, In: J NEUROSCI. 36, 11, p. 3127-44 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Knock-Down of Hippocampal DISC1 in Immune-Challenged Mice Impairs the Prefrontal-Hippocampal Coupling and the Cognitive Performance Throughout Development
Xu, X., Song, L. & Hanganu-Opatz, I. L., 05.01.2021, In: CEREB CORTEX. 31, 2, p. 1240-1258 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Layer-specific impairment in the developing lateral entorhinal cortex of immune-challenged Disc1+/- mice
Kringel, R., Song, L., Xu, X., Bitzenhofer, S. H. & Hanganu-Opatz, I. L., 02.2023, In: J PHYSIOL-LONDON. 601, 4, p. 847-857 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Layer-specific optogenetic activation of pyramidal neurons causes beta-gamma entrainment of neonatal networks
Bitzenhofer, S. H., Ahlbeck, J., Wolff, A., Wiegert, J. S., Gee, C. E., Oertner, T. G. & Hanganu-Opatz, I. L., 20.02.2017, In: NAT COMMUN. 8, p. 14563Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Methodological Approach for Optogenetic Manipulation of Neonatal Neuronal Networks
Bitzenhofer, S. H., Ahlbeck, J. & Hanganu-Opatz, I. L., 2017, In: FRONT CELL NEUROSCI. 11, p. 239Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multisensory integration in rodent tactile but not visual thalamus
Bieler, M., Xu, X., Marquardt, A. & Hanganu-Opatz, I. L., 24.10.2018, In: SCI REP-UK. 8, 1, p. 15684Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neocortical Layer 6B as a Remnant of the Subplate - A Morphological Comparison
Marx, M., Qi, G., Hanganu-Opatz, I. L., Kilb, W., Luhmann, H. J. & Feldmeyer, D., 01.02.2017, In: CEREB CORTEX. 27, 2, p. 1011-1026Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neonatal cholinergic lesion alters the acoustic structure of infant rat vocalization but not the early cognitive development.
Krüger, H-S. & Hanganu-Opatz, I. L., 2013, In: DEV PSYCHOBIOL. 55, 3, p. 294-308 15 p., 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neonatal hippocampal lesion alters the functional maturation of the prefrontal cortex and the early cognitive development in pre-juvenile rats.
Krüger, H-S., Brockmann, M. D., Salamon, J. M., Ittrich, H. & Hanganu-Opatz, I., 2012, In: NEUROBIOL LEARN MEM. 97, 4, p. 470-481 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neonatal hypoxia-ischemia impairs juvenile recognition memory by disrupting the maturation of prefrontal-hippocampal networks
Domnick, N-K., Gretenkord, S., De Feo, V., Sedlacik, J., Brockmann, M. D. & Hanganu-Opatz, I. L., 11.2015, In: EXP NEUROL. 273, p. 202-14 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neonatal Restriction of Tactile Inputs Leads to Long-Lasting Impairments of Cross-Modal Processing
Sieben, K., Bieler, M., Röder, B. & Hanganu-Opatz, I. L., 11.2015, In: PLOS BIOL. 13, 11, p. Art. e1002304Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neural Correlates of Anesthesia in Newborn Mice and Humans
Chini, M., Gretenkord, S., Kostka, J. K., Pöpplau, J. A., Cornelissen, L., Berde, C. B., Hanganu-Opatz, I. L. & Bitzenhofer, S. H., 2019, In: FRONT NEURAL CIRCUIT. 13, p. 38Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Olfactory bulb activity shapes the development of entorhinal-hippocampal coupling and associated cognitive abilities
Chen, Y-N., Kostka, J. K., Bitzenhofer, S. H. & Hanganu-Opatz, I. L., 23.10.2023, In: CURR BIOL. 33, 20, p. 4353-4366.e5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Olfactory-driven beta band entrainment of limbic circuitry during neonatal development
Kostka, J. K. & Hanganu-Opatz, I. L., 08.2023, In: J PHYSIOL-LONDON. 601, 16, p. 3605-3630 26 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Oscillatory activity in developing prefrontal networks results from theta-gamma-modulated synaptic inputs.
Bitzenhofer, S., Sieben, K., Spehr, M. & Hanganu-Opatz, I., 21.04.2015, In: CELL REP. 11, 3, p. 486-497Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Oscillatory coupling within neonatal prefrontal-hippocampal networks is independent of selective removal of GABAergic neurons in the hippocampus
Bitzenhofer, S. H. & Hanganu-Opatz, I. L., 01.02.2014, In: NEUROPHARMACOLOGY. 77, p. 57-67 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing.
Sieben, K., Röder, B. & Hanganu-Opatz, I. L., 2013, In: J NEUROSCI. 33, 13, p. 5736-5749 14 p., 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice
Schepanski, S., Chini, M., Sternemann, V., Urbschat, C., Thiele, K., Sun, T., Zhao, Y., Poburski, M., Woestemeier, A., Thieme, M-T., Zazara, D. E., Alawi, M., Fischer, N., Heeren, J., Vladimirov, N., Woehler, A., Puelles, V. G., Bonn, S., Gagliani, N., Hanganu-Opatz, I. L. & Arck, P. C., 05.08.2022, In: NAT COMMUN. 13, 1, 4571.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rate and Temporal Coding Convey Multisensory Information in Primary Sensory Cortices
Bieler, M., Sieben, K., Cichon, N., Schildt, S., Röder, B. & Hanganu-Opatz, I. L., 05.04.2017, In: ENEURO. 4, 2, p. UNSP e0037Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reorganization of adolescent prefrontal cortex circuitry is required for mouse cognitive maturation
Pöpplau, J. A., Schwarze, T., Dorofeikova, M., Pochinok, I., Günther, A., Marquardt, A. & Hanganu-Opatz, I. L., 07.02.2024, In: NEURON. 112, 3, p. 421-440.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment
Chini, M., Pöpplau, J. A., Lindemann, C., Carol-Perdiguer, L., Hnida, M., Oberländer, V., Xu, X., Ahlbeck, J., Bitzenhofer, S. H., Mulert, C. & Hanganu-Opatz, I. L., 08.01.2020, In: NEURON. 105, 1, p. 60-74.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resting-state connectivity in the prodromal phase of schizophrenia: insights from EEG microstates
Andreou, C., Faber, P. L., Leicht, G., Schoettle, D., Polomac, N., Hanganu-Opatz, I. L., Lehmann, D. & Mulert, C., 01.02.2014, In: SCHIZOPHR RES. 152, 2-3, p. 513-20 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resting-state theta-band connectivity and verbal memory in schizophrenia and in the high-risk state
Andreou, C., Leicht, G., Nolte, G., Polomac, N., Moritz, S., Karow, A., Hanganu-Opatz, I. L., Engel, A. K. & Mulert, C., 02.2015, In: SCHIZOPHR RES. 161, 2-3, p. 299-307 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sparser and Less Efficient Hippocampal-Prefrontal Projections account for Developmental Network Dysfunction in a Model of Psychiatric Risk Mediated by Gene-Environment Interaction
Song, L., Xu, X., Putthoff, P., Fleck, D., Spehr, M. & Hanganu-Opatz, I. L., 26.01.2022, In: J NEUROSCI. 42, 4, p. 601-618 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Subplate cells: amplifiers of neuronal activity in the developing cerebral cortex.
Luhmann, H. J., Kilb, W. & Hanganu-Opatz, I., 2009, In: FRONT NEUROANAT. 3, p. 19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review