Dr. ID: 58782
Harriet Wikman-Kocher
Publications
- 2016
Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
Bednarz-Knoll, N., Efstathiou, A., Gotzhein, F., Wikman, H., Mueller, V., Kang, Y. & Pantel, K., 02.2016, In: CLIN CHEM. 62, 2, p. 378-386Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
Hvichia, G. E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R. P. L., Stoecklein, N. H., Wikman, H., Riethdorf, S., Pantel, K. & Gorges, T. M., 20.01.2016, In: INT J CANCER. 138, 12, p. 2894-904Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Breast cancer brain metastases:biology and new clinical perspectives
Witzel, I., Oliveira-Ferrer, L., Pantel, K., Müller, V. & Wikman, H., 19.01.2016, In: BREAST CANCER RES. 18, 1, p. 8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of different CTC subpopulations in non-small cell lung cancer
Hanssen, A., Wagner, J., Gorges, T. M., Tänzer, A., Uzunoglu, F. G., Driemel, C., Stoecklein, N. H., Knoefel, W. T., Angenendt, S., Hauch, S., Atanackovic, D., Loges, S., Riethdorf, S., Pantel, K. & Wikman, H., 2016, In: SCI REP-UK. 6, p. 28010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak, K., Kwiatkowski, M., Buck, F., Gorges, T. M., Nilse, L., Assmann, V., Andreas, A., Müller, V., Wikman, H., Riethdorf, S., Schlüter, H. & Pantel, K., 15.12.2015, In: CANCER RES. 75, 24, p. 5367-77 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
Harter, P. N., Bernatz, S., Scholz, A., Zeiner, P. S., Zinke, J., Kiyose, M., Blasel, S., Beschorner, R., Senft, C., Bender, B., Ronellenfitsch, M. W., Wikman-Kocher, H., Glatzel, M., Meinhardt, M., Juratli, T. A., Steinbach, J. P., Plate, K. H., Wischhusen, J., Weide, B. & Mittelbronn, M., 12.2015, In: ONCOTARGET. 6, 38, p. 40836-40849Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Bednarz-Knoll, N., Nastały, P., Żaczek, A., Stoupiec, M., Riethdorf, S., Wikman-Kocher, H., Müller, V., Skokowski, J., Szade, J., Sejda, A., Wełnicka-Jaśkiewicz, M. & Pantel, K., 29.09.2015, In: ONCOTARGET. 6, 29, p. 26789-803 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer
Hanssen, A., Loges, S., Pantel, K. & Wikman-Kocher, H., 22.09.2015, In: FRONT ONCOL. 5, p. Art. 207Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients
Milde-Langosch, K., Schütze, D., Oliveira-Ferrer, L., Wikman-Kocher, H., Müller, V., Lebok, P., Pantel, K., Schröder, C., Witzel, I. & Schumacher, U., 06.2015, In: BREAST CANCER RES TR. 151, 3, p. 515-28 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of HERC5 and its potential role in NSCLC progression
Wrage, M., Hagmann, W., Kemming, D., Uzunoglu, F. G., Riethdorf, S., Harms-Effenberger, K., Westphal, M., Lamszus, K., Kim, S-Z., Becker, N., Izbicki, J. R., Sandoval, J., Esteller, M., Pantel, K., Risch, A. & Wikman-Kocher, H., 15.05.2015, In: INT J CANCER. 136, 10, p. 2264-72Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells
Werner, S., Stamm, H., Pandjaitan, M., Kemming, D., Brors, B., Pantel, K. & Wikman, H., 2015, In: BMC CANCER. 15, 1, p. 896Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2
Werner, S., Brors, B., Eick, J., Marques, E., Pogenberg, V., Parret, A., Kemming, D., Wood, A. W., Edgren, H., Neubauer, H., Streichert, T., Riethdorf, S., Bedi, U., Baccelli, I., Jücker, M., Eils, R., Fehm, T., Trumpp, A., Johnsen, S. A., Klefstrom, J., Wilmanns, M., Müller, V., Pantel, K. & Wikman-Kocher, H., 2015, In: CANCER DISCOV. 5, 5, p. 506-19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
Eichelser, C., Stückrath, I., Müller, V., Milde-Langosch, K., Wikman-Kocher, H., Pantel, K. & Schwarzenbach, H., 30.10.2014, In: ONCOTARGET. 5, 20, p. 9650-63 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
LeBleu, V. S., O'Connell, J. T., Gonzalez Herrera, K. N., Wikman-Kocher, H., Pantel, K., Haigis, M. C., de Carvalho, F. M., Damascena, A., Domingos Chinen, L. T., Rocha, R. M., Asara, J. M. & Kalluri, R., 01.10.2014, In: NAT CELL BIOL. 16, 10, p. 992-1003Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Wikman-Kocher, H., Westphal, L., Schmid, F., Pollari, S., Kropidlowski, J., Sielaff-Frimpong, B., Glatzel, M., Matschke, J., Westphal, M., Iljin, K., Huhtala, H., Terracciano, L., Kallioniemi, A., Sauter, G., Müller, V., Witzel, I., Lamszus, K., Kemming, D. & Pantel, K., 16.03.2014, In: ONCOTARGET. 5, 10, p. 3076-3087Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of 4q21.23-22.1 is a Prognostic Marker for Disease Free and Overall Survival in Non-Small Cell Lung Cancer
Uzunoglu, F. G., Dethlefsen, E., Hanssen, A., Wrage, M., Deutsch, L., Harms-Effenberger, K., Vashist, Y. K., Reeh, M., Sauter, G., Simon, R., Bockhorn, M., Pantel, K., Izbicki, J. R. & Wikman-Kocher, H., 01.01.2014, In: PLOS ONE. 9, 12, p. e113315Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC
Uzunoglu, F. G., Yavari, N., Bohn, B. A., Nentwich, M. F., Reeh, M., Pantel, K., Perez, D., Tsui, T. Y., Bockhorn, M., Mann, O., Izbicki, J. R., Wikman, H. & Vashist, Y. K., 01.07.2013, In: LUNG CANCER. 81, 1, p. 123-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
Hohensee, I., Lamszus, K., Riethdorf, S., Meyer-Staeckling, S., Glatzel, M., Matschke, J., Witzel, I., Westphal, M., Brandt, B., Müller, V., Pantel, K. & Wikman, H., 01.07.2013, In: AM J PATHOL. 183, 1, p. 83-95 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma
Uzunoglu, F. G., Kolbe, J., Wikman, H., Güngör, C., Bohn, B. A., Nentwich, M. F., Reeh, M., König, A. M., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y. K., 01.05.2013, In: ANN ONCOL. 24, 5, p. 1282-90 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients
Nymark, P., Aavikko, M., Mäkilä, J., Ruosaari, S., Hienonen-Kempas, T., Wikman, H., Salmenkivi, K., Pirinen, R., Karjalainen, A., Vanhala, E., Kuosma, E., Anttila, S. & Kettunen, E., 01.02.2013, In: MOL ONCOL. 7, 1, p. 29-40 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Lehtinen, L., Vainio, P., Wikman, H., Reemts, J., Hilvo, M., Issa, R., Pollari, S., Brandt, B., Oresic, M., Pantel, K., Kallioniemi, O. & Iljin, K., 2012, In: J PATHOL. 226, 4, p. 674-686 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumor-derived biomarkers in lung cancer.
Tänzer, A., Alix-Panabières, C., Wikman, H. & Pantel, K., 2012, In: J THORAC DIS. 4, 5, p. 448-449 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
Wikman, H., Sielaff-Frimpong, B., Kropidlowski, J., Witzel, I., Milde-Langosch, K., Sauter, G., Westphal, M., Lamszus, K. & Pantel, K., 2012, In: PLOS ONE. 7, 10, p. 47537 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Deutsch, L., Wrage, M., Koops, S., Glatzel, M., Uzunoglu, F. G., Kutup, A., Hinsch, A., Sauter, G., Izbicki, J. R., Pantel, K. & Wikman, H., 2012, In: GENE CHROMOSOME CANC. 51, 6, p. 618-629 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman, H., Lamszus, K., Detels, N., Uslar, L., Wrage, M., Benner, C., Hohensee, I., Ylstra, B., Eylmann, K., Zapatka, M., Sauter, G., Kemming, D., Glatzel, M., Müller, V., Westphal, M. & Pantel, K., 2012, In: BREAST CANCER RES. 14, 2, p. 49 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Uzunoglu, F. G., Kaufmann, C., Wikman, H., Güngör, C., Bohn, B., Nentwich, M., Reeh, M., Pantel, K., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y., 2012, In: ANN SURG ONCOL. 19, 7, p. 2159-2168 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein, S., Müller, V., Köhler, N., Wikman, H., Krenkel, S., Streichert, T., Schweizer, M., Riethdorf, S., Assmann, V., Henningsen, M., Beck, K., Issa, R., Jänicke, F., Pantel, K. & Milde-Langosch, K., 2011, In: BREAST CANCER RES TR. 129, 2, p. 347-360 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure.
Kettunen, E., Aavikko, M., Nymark, P., Ruosaari, S., Wikman, H., Vanhala, E., Salmenkivi, K., Pirinen, R., Karjalainen, A., Kuosma, E. & Anttila, S., 2009, In: BRIT J CANCER. 100, 8, p. 1336-1342 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Wrage, M., Ruosaari, S., Eijk, P. P., Kaifi, J., Hollmén, J., Yekebas, E. F., Izbicki, J. R., Brakenhoff, R. H., Streichert, T., Riethdorf, S., Glatzel, M., Ylstra, B., Pantel, K. & Wikman, H., 2009, In: CLIN CANCER RES. 15, 5, p. 1566-1574 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.
Cote, M. L., Chen, W., Smith, D. W., Benhamou, S., Bouchardy, C., Butkiewicz, D., Fong, K. M., Gené, M., Hirvonen, A., Kiyohara, C., Larsen, J. E., Lin, P., Raaschou-Nielsen, O., Povey, A. C., Reszka, E., Risch, A., Schneider, J., Schwartz, A. G., Sorensen, M., Figueras, J. T., Tokudome, S., Pu, Y., Yang, P., Wenzlaff, A. S., Wikman, H. & Taioli, E., 2009, In: AM J EPIDEMIOL. 169, 7, p. 802-814 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.
Nymark, P., Kettunen, E., Aavikko, M., Ruosaari, S., Kuosma, E., Vanhala, E., Salmenkivi, K., Pirinen, R., Karjalainen, A., Knuutila, S., Wikman, H. & Anttila, S., 2009, In: CLIN CANCER RES. 15, 2, p. 468-475 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Cancer micrometastasis and tumour dormancy.
Wikman, H., Vessella, R. & Pantel, K., 2008, In: APMIS. 116, 7-8, p. 754-770 7-8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular and genetic changes in asbestos-related lung cancer.
Nymark, P., Wikman, H., Hienonen-Kempas, T. & Anttila, S., 2008, In: CANCER LETT. 265, 1, p. 1-15 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.
Ruosaari, S., Hienonen-Kempas, T., Puustinen, A., Sarhadi, V. K., Hollmén, J., Knuutila, S., Saharinen, J., Wikman, H. & Anttila, S., 2008, In: BMC MED GENOMICS. 1, p. 55Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Review: Biological relevance of disseminated tumor cells in cancer patients.
Riethdorf, S., Wikman, H. & Pantel, K., 2008, In: INT J CANCER. 123, 9, p. 1991-2006 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
Wikman, H., Ruosaari, S., Nymark, P., Sarhadi, V. K., Saharinen, J., Vanhala, E., Karjalainen, A., Hollmén, J., Knuutila, S. & Anttila, S., 2007, In: ONCOGENE. 26, 32, p. 4730-4737 32.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review