Prof.Dr.rer.nat ID: 15692247
Immo Prinz
Publications
- 2023
Human γδ T cell Identification from Single-cell RNA Sequencing Datasets by Modular TCR Expression
Song, Z., Henze, L., Casar, C., Schwinge, D., Schramm, C., Fuss, J., Tan, L. & Prinz, I., 24.11.2023, In: J LEUKOCYTE BIOL. 114, 6, p. 630-638 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery
Yang, T., Barros-Martins, J., Wang, Z., Wencker, M., Zhang, J., Smout, J., Gambhir, P., Janssen, A., Schimrock, A., Georgiev, H., León-Lara, X., Weiss, S., Huehn, J., Prinz, I., Krueger, A., Foerster, R., Walzer, T. & Ravens, S., 31.10.2023, In: CELL REP. 42, 10, p. 113230Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts
Picard, F. S. R., Lutz, V., Brichkina, A., Neuhaus, F., Ruckenbrod, T., Hupfer, A., Raifer, H., Klein, M., Bopp, T., Pfefferle, P. I., Savai, R., Prinz, I., Waisman, A., Moos, S., Chang, H-D., Heinrich, S., Bartsch, D. K., Buchholz, M., Singh, S., Tu, M., Klein, L., Bauer, C., Liefke, R., Burchert, A., Chung, H-R., Mayer, P., Gress, T. M., Lauth, M., Gaida, M. & Huber, M., 08.2023, In: GUT. 72, 8, p. 1510-1522 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 signaling in keratinocytes orchestrates the defense against Staphylococcus aureus skin infection
Moos, S., Regen, T., Wanke, F., Tian, Y., Arendholz, L., Hauptmann, J., Heinen, A. P., Bleul, L., Bier, K., El Malki, K., Reinhardt, C., Prinz, I., Diefenbach, A., Wolz, C., Schittek, B., Waisman, A. & Kurschus, F. C., 07.2023, In: J INVEST DERMATOL. 143, 7, p. 1257-1267.e10Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcriptional and Clonal Characterization of Cytotoxic T Cells in Crescentic Glomerulonephritis
Mueller, A., Zhao, Y., Cicek, H., Paust, H-J., Sivayoganathan, A., Linke, A., Wegscheid, C., Wiech, T., Huber, T. B., Meyer-Schwesinger, C., Bonn, S., Prinz, I., Panzer, U., Tiegs, G., Krebs, C. F. & Neumann, K., 01.06.2023, In: J AM SOC NEPHROL. 34, 6, p. 1003-1018 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antigen-specific γδ T cells contribute to cytomegalovirus control after stem cell transplantation
Prinz, I. & Koenecke, C., 06.2023, In: CURR OPIN IMMUNOL. 82, p. 102303Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Individual Epitope-Specific CD8+ T Cell Immune Responses Are Shaped Differently during Chronic Viral Infection
Klein, S., Mischke, J., Beruldsen, F., Prinz, I., Antunes, D. A., Cornberg, M. & Kraft, A. R. M., 14.05.2023, In: PATHOGENS. 12, 5, 716.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency
Deng, L., Ly, C., Abdollahi, S., Zhao, Y., Prinz, I. & Bonn, S., 18.04.2023, In: FRONT IMMUNOL. 14, p. 1128326Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages
Hahn, A., Vogg, L., Brey, S., Schneider, A., Schäfer, S., Palmisano, R., Pavlova, A., Sandrock, I., Tan, L., Fichtner, A. S., Prinz, I., Ravens, S. & Winkler, T. H., 28.03.2023, In: CELL REP. 42, 3, p. 112253 112253.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou, A. D., Kempski, J., Shiri, A. M., Lücke, J., Zhang, T., Zhao, L., Zazara, D. E., Cortesi, F., Riecken, K., Amezcua Vesely, M. C., Low, J. S., Xu, H., Kaffe, E., Garcia-Perez, L., Agalioti, T., Yamada, Y., Jungraithmayr, W., Zigmond, E., Karstens, K-F., Steglich, B., Wagner, J., Konczalla, L., Carambia, A., Schulze, K., von Felden, J., May, P., Briukhovetska, D., Bedke, T., Brockmann, L., Starzonek, S., Lange, T., Koch, C., Riethdorf, S., Pelczar, P., Böttcher, M., Sabihi, M., Huber, F. J., Reeh, M., Grass, J. K., Wahib, R., Seese, H., Stüben, B-O., Fard-Aghaie, M., Duprée, A., Scognamiglio, P., Plitzko, G., Meiners, J., Soukou, S., Wittek, A., Manthey, C., Maroulis, I. C., Arck, P. C., Perez, D., Gao, B., Zarogiannis, S. G., Strowig, T., Pasqualini, R., Arap, W., Gosálvez, J. S., Kobold, S., Prinz, I., Guse, A. H., Tachezy, M., Ghadban, T., Heumann, A., Li, J., Melling, N., Mann, O., Izbicki, J. R., Pantel, K., Schumacher, U., Lohse, A. W., Flavell, R. A., Gagliani, N. & Huber, S., 10.01.2023, In: IMMUNITY. 56, 1, p. 125-142.e12Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Kidney-resident innate-like memory γδ T cells control chronic Staphylococcus aureus infection of mice
Bertram, T., Reimers, D., Lory, N. C., Schmidt, C., Schmid, J., C Heinig, L., Bradtke, P., Rattay, G., Zielinski, S., Hellmig, M., Bartsch, P., Rohde, H., Nuñez, S., Rosemblatt, M. V., Bono, M. R., Gagliani, N., Sandrock, I., Panzer, U., Krebs, C. F., Meyer-Schwesinger, C., Prinz, I. & Mittrücker, H-W., 03.01.2023, In: P NATL ACAD SCI USA. 120, 1, p. e2210490120Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcriptomic profile of TNFhigh MAIT cells is linked to B cell response following SARS-CoV-2 vaccination
Marzano, P., Balin, S., Terzoli, S., Della Bella, S., Cazzetta, V., Piazza, R., Sandrock, I., Ravens, S., Tan, L., Prinz, I., Calcaterra, F., Di Vito, C., Cancellara, A., Calvi, M., Carletti, A., Franzese, S., Frigo, A., Darwish, A., Voza, A., Mikulak, J. & Mavilio, D., 2023, In: FRONT IMMUNOL. 14, p. 1208662Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Interleukin-23 receptor expressing γδ T cells locally promote early atherosclerotic lesion formation and plaque necrosis in mice
Gil-Pulido, J., Amézaga, N., Jorgacevic, I., Manthey, H. D., Rösch, M., Brand, T., Cidlinsky, P., Schäfer, S., Beilhack, A., Saliba, A-E., Lorenz, K., Boon, L., Prinz, I., Waisman, A., Korn, T., Cochain, C. & Zernecke, A., 10.11.2022, In: CARDIOVASC RES. 118, 14, p. 2932-2945 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cross-Reactive T Cell Response Exists in Chronic Lymphocytic Choriomeningitis Virus Infection upon Pichinde Virus Challenge
Mischke, J., Klein, S., Seamann, A., Prinz, I., Selin, L., Ghersi, D., Cornberg, M. & Kraft, A. R. M., 18.10.2022, In: VIRUSES-BASEL. 14, 10, 2293.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
Ataide, M. A., Knöpper, K., Cruz de Casas, P., Ugur, M., Eickhoff, S., Zou, M., Shaikh, H., Trivedi, A., Grafen, A., Yang, T., Prinz, I., Ohlsen, K., Gomez de Agüero, M., Beilhack, A., Huehn, J., Gaya, M., Saliba, A-E., Gasteiger, G. & Kastenmüller, W., 11.10.2022, In: IMMUNITY. 55, 10, p. 1813-1828.e9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Corrigendum: Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Deng, L., Harms, A., Ravens, S., Prinz, I. & Tan, L., 06.10.2022, In: FRONT IMMUNOL. 13, p. 1055103Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
OMIP-084: 28-color full spectrum flow cytometry panel for the comprehensive analysis of human γδ T cells
Barros-Martins, J., Bruni, E., Fichtner, A. S., Cornberg, M. & Prinz, I., 10.2022, In: CYTOM PART A. 101, 10, p. 856-861 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status
Deng, L., Harms, A., Ravens, S., Prinz, I. & Tan, L., 27.09.2022, In: FRONT IMMUNOL. 13, 960920.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Healthy-like CD4+ Regulatory and CD4+ Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
Schneider, J., Kuhlmann, L., Xiao, Y., Raha, S., Bernhardt, G., Stadler, M., Thol, F., Heuser, M., Eder, M., Ganser, A., Ravens, S., Förster, R., Prinz, I., Koenecke, C. & Schultze-Florey, C. R., 18.09.2022, In: INT J MOL SCI. 23, 18, 10914.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-Dose Mycobacterium tuberculosis H37rv Infection in IL-17A- and IL-17A/F-Deficient Mice
Ritter, K., Behrends, J., Rückerl, D., Hölscher, A., Volz, J., Prinz, I. & Hölscher, C., 14.09.2022, In: CELLS-BASEL. 11, 18, 2875.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR
Deseke, M., Rampoldi, F., Sandrock, I., Borst, E., Böning, H., Ssebyatika, G. L., Jürgens, C., Plückebaum, N., Beck, M., Hassan, A., Tan, L., Demera, A., Janssen, A., Steinberger, P., Koenecke, C., Viejo-Borbolla, A., Messerle, M., Krey, T. & Prinz, I., 05.09.2022, In: J EXP MED. 219, 9, e20212525.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inflammation triggers ILC3 patrolling of the intestinal barrier
Jarade, A., Garcia, Z., Marie, S., Demera, A., Prinz, I., Bousso, P., Di Santo, J. P. & Serafini, N., 09.2022, In: NAT IMMUNOL. 23, 9, p. 1317-1323 7 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Intrahepatic CD69+Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression
Bruni, E., Cimino, M. M., Donadon, M., Carriero, R., Terzoli, S., Piazza, R., Ravens, S., Prinz, I., Cazzetta, V., Marzano, P., Kunderfranco, P., Peano, C., Soldani, C., Franceschini, B., Colombo, F. S., Garlanda, C., Mantovani, A., Torzilli, G., Mikulak, J. & Mavilio, D., 07.2022, In: J IMMUNOTHER CANCER. 10, 7, e004579.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New insights on murine γδ T cells from single-cell multi-omics
Tan, L., Inácio, D., Prinz, I. & Silva-Santos, B., 15.06.2022, In: SCI BULL. 67, 11, p. 1102-1104 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
γδ T cells license immature B cells to produce a broad range of polyreactive antibodies
Rampoldi, F., Donato, E., Ullrich, L., Deseke, M., Janssen, A., Demera, A., Sandrock, I., Bubke, A., Juergens, A-L., Swallow, M., Sparwasser, T., Falk, C., Tan, L., Trumpp, A. & Prinz, I., 24.05.2022, In: CELL REP. 39, 8, 110854.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A-producing γδT cells promote muscle regeneration in a microbiota-dependent manner
Mann, A. O., Hanna, B. S., Muñoz-Rojas, A. R., Sandrock, I., Prinz, I., Benoist, C. & Mathis, D., 02.05.2022, In: J EXP MED. 219, 5, e20211504.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T Cells Differentially Regulate Bone Loss in Periodontitis Models
Barel, O., Aizenbud, Y., Tabib, Y., Jaber, Y., Leibovich, A., Horev, Y., Zubeidat, K., Saba, Y., Eli-Berchoer, L., Heyman, O., Wilensky, A., Prinz, I. & Hovav, A. H., 04.2022, In: J DENT RES. 101, 4, p. 428-436 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Three Layers of Intestinal γδ T Cells Talk Different Languages With the Microbiota
Rampoldi, F. & Prinz, I., 24.03.2022, In: FRONT IMMUNOL. 13, 849954.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Interleukin-17 is disease promoting in early stages and protective in late stages of experimental periodontitis
Wilharm, A., Binz, C., Sandrock, I., Rampoldi, F., Lienenklaus, S., Blank, E., Winkel, A., Demera, A., Hovav, A-H., Stiesch, M. & Prinz, I., 17.03.2022, In: PLOS ONE. 17, 3, e0265486.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ intraepithelial lymphocytes facilitate pathological epithelial cell shedding via CD103-mediated granzyme release
Hu, M. D., Golovchenko, N. B., Burns, G. L., Nair, P. M., Kelly, T. J., Agos, J., Irani, M. Z., Soh, W. S., Zeglinski, M. R., Lemenze, A., Bonder, E. M., Sandrock, I., Prinz, I., Granville, D. J., Keely, S., Watson, A. J. M. & Edelblum, K. L., 03.2022, In: GASTROENTEROLOGY. 162, 3, p. 877-889.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis
Dywicki, J., Buitrago-Molina, L. E., Noyan, F., Davalos-Misslitz, A. C., Hupa-Breier, K. L., Lieber, M., Hapke, M., Schlue, J., Falk, C. S., Raha, S., Prinz, I., Koenecke, C., Manns, M. P., Wedemeyer, H., Hardtke-Wolenski, M. & Jaeckel, E., 02.2022, In: HEPATOL COMMUN. 6, 2, p. 320-333 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7
Coppin, E., Sundarasetty, B. S., Rahmig, S., Blume, J., Verheyden, N. A., Bahlmann, F., Ravens, S., Schubert, U., Schmid, J., Ludwig, S., Geissler, K., Guntinas-Lichius, O., von Kaisenberg, C., Groten, T., Platz, A., Naumann, R., Ludwig, B., Prinz, I., Waskow, C. & Krueger, A., 12.2021, In: LEUKEMIA. 35, 12, p. 3561-3567 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Cossarizza, A., Chang, H-D., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., Bacher, P., Bari, S., Barnaba, V., Barros-Martins, J., Baumjohann, D., Beccaria, C. G., Bernardo, D., Boardman, D. A., Borger, J., Böttcher, C., Brockmann, L., Burns, M., Busch, D. H., Cameron, G., Cammarata, I., Cassotta, A., Chang, Y., Chirdo, F. G., Christakou, E., Čičin-Šain, L., Cook, L., Corbett, A. J., Cornelis, R., Cosmi, L., Davey, M. S., De Biasi, S., De Simone, G., Del Zotto, G., Delacher, M., Di Rosa, F., Santo, J. D., Diefenbach, A., Dong, J., Dörner, T., Dress, R. J., Dutertre, C-A., Eckle, S. B. G., Eede, P., Evrard, M., Falk, C. S., Feuerer, M., Fillatreau, S., Fiz-Lopez, A., Follo, M., Foulds, G. A., Fröbel, J., Gagliani, N., Galletti, G., Gangaev, A., Garbi, N., Garrote, J. A., Geginat, J., Gherardin, N. A., Gibellini, L., Ginhoux, F., Godfrey, D. I., Gruarin, P., Haftmann, C., Hansmann, L., Harpur, C. M., Hayday, A. C., Heine, G., Hernández, D. C., Herrmann, M., Hoelsken, O., Huang, Q., Huber, S., Huber, J. E., Huehn, J., Hundemer, M., Hwang, W. Y. K., Iannacone, M., Ivison, S. M., Jäck, H-M., Jani, P. K., Keller, B., Kessler, N., Ketelaars, S., Knop, L., Knopf, J., Koay, H-F., Kobow, K., Kriegsmann, K., Kristyanto, H., Krueger, A., Kuehne, J. F., Kunze-Schumacher, H., Kvistborg, P., Kwok, I., Latorre, D., Lenz, D., Levings, M. K., Lino, A. C., Liotta, F., Long, H. M., Lugli, E., MacDonald, K. N., Maggi, L., Maini, M. K., Mair, F., Manta, C., Manz, R. A., Mashreghi, M-F., Mazzoni, A., McCluskey, J., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Monin, L., Moretta, L., Multhoff, G., Muñoz, L. E., Muñoz-Ruiz, M., Muscate, F., Natalini, A., Neumann, K., Ng, L. G., Niedobitek, A., Niemz, J., Almeida, L. N., Notarbartolo, S., Ostendorf, L., Pallett, L. J., Patel, A. A., Percin, G. I., Peruzzi, G., Pinti, M., Pockley, A. G., Pracht, K., Prinz, I., Pujol-Autonell, I., Pulvirenti, N., Quatrini, L., Quinn, K. M., Radbruch, H., Rhys, H., Rodrigo, M. B., Romagnani, C., Saggau, C., Sakaguchi, S., Sallusto, F., Sanderink, L., Sandrock, I., Schauer, C., Scheffold, A., Scherer, H. U., Schiemann, M., Schildberg, F. A., Schober, K., Schoen, J., Schuh, W., Schüler, T., Schulz, A. R., Schulz, S., Schulze, J., Simonetti, S., Singh, J., Sitnik, K. M., Stark, R., Starossom, S., Stehle, C., Szelinski, F., Tan, L., Tarnok, A., Tornack, J., Tree, T. I. M., van Beek, J. J. P., van de Veen, W., van Gisbergen, K., Vasco, C., Verheyden, N. A., von Borstel, A., Ward-Hartstonge, K. A., Warnatz, K., Waskow, C., Wiedemann, A., Wilharm, A., Wing, J., Wirz, O., Wittner, J., Yang, J. H. M. & Yang, J., 12.2021, In: EUR J IMMUNOL. 51, 12, p. 2708-3145 438 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Piepke, M., Clausen, B. H., Ludewig, P., Vienhues, J. H., Bedke, T., Javidi, E., Rissiek, B., Jank, L., Brockmann, L., Sandrock, I., Degenhardt, K., Jander, A., Roth, V., Schädlich, I. S., Prinz, I., Flavell, R. A., Kobayashi, Y., Renné, T., Gerloff, C., Huber, S., Magnus, T. & Gelderblom, M., 13.11.2021, In: J NEUROINFLAMM. 18, 1, 265.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI
Schultze-Florey, C. R., Kuhlmann, L., Raha, S., Barros-Martins, J., Odak, I., Tan, L., Xiao, Y., Ravens, S., Hambach, L., Venturini, L., Stadler, M., Eder, M., Thol, F., Heuser, M., Forster, R., Ganser, A., Prinz, I. & Koenecke, C., 09.11.2021, In: BLOOD ADV. 5, 21, p. 4485-4499 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin-23 instructs protective multifunctional CD4 T cell responses after immunization with the Mycobacterium tuberculosis subunit vaccine H1 DDA/TDB independently of interleukin-17A
Ritter, K., Behrends, J., Erdmann, H., Rousseau, J., Hölscher, A., Volz, J., Prinz, I., Lindenstrøm, T. & Hölscher, C., 11.2021, In: J MOL MED. 99, 11, p. 1585-1602 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
αβ T cells replacing dermal and epidermal γδ T cells in Tcrd-/- mice express an MHC-independent TCR repertoire
Binz, C., Bubke, A., Sandrock, I. & Prinz, I., 11.2021, In: EUR J IMMUNOL. 51, 11, p. 2618-2632 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions
Cazzetta, V., Bruni, E., Terzoli, S., Carenza, C., Franzese, S., Piazza, R., Marzano, P., Donadon, M., Torzilli, G., Cimino, M., Simonelli, M., Bello, L., Villa, A., Tan, L., Ravens, S., Prinz, I., Supino, D., Colombo, F. S., Lugli, E., Marcenaro, E., Vivier, E., Della Bella, S., Mikulak, J. & Mavilio, D., 19.10.2021, In: CELL REP. 37, 3, 109871.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry
Schultze-Florey, C. R., Chukhno, E., Goudeva, L., Blasczyk, R., Ganser, A., Prinz, I., Förster, R., Koenecke, C. & Odak, I., 10.2021, In: LEUKEMIA. 35, 10, p. 3021-3025 5 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Lack of gamma delta T cells ameliorates inflammatory response after acute intestinal ischemia reperfusion in mice
Funken, D., Yu, Y., Feng, X., Imvised, T., Gueler, F., Prinz, I., Madadi-Sanjani, O., Ure, B. M., Kuebler, J. F. & Klemann, C., 20.09.2021, In: SCI REP-UK. 11, 1, p. 18628Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδT Cells Are Essential for Orthodontic Tooth Movement
Wald, S., Leibowitz, A., Aizenbud, Y., Saba, Y., Zubeidat, K., Barel, O., Koren, N., Heyman, O., Wilharm, A., Sandrock, I., Fleissig, O., Tal, Y., Prinz, I., Aizenbud, D., Chaushu, S. & Hovav, A. H., 07.2021, In: J DENT RES. 100, 7, p. 731-738 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development in mice
Elfaki, Y., Robert, P. A., Binz, C., Falk, C. S., Bruder, D., Prinz, I., Floess, S., Meyer-Hermann, M. & Huehn, J., 05.2021, In: EUR J IMMUNOL. 51, 5, p. 1166-1181 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood
Tan, L., Fichtner, A. S., Bruni, E., Odak, I., Sandrock, I., Bubke, A., Borchers, A., Schultze-Florey, C., Koenecke, C., Förster, R., Jarek, M., von Kaisenberg, C., Schulz, A., Chu, X., Zhang, B., Li, Y., Panzer, U., Krebs, C. F., Ravens, S. & Prinz, I., 23.04.2021, In: SCI IMMUNOL. 6, 58Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions
Koren, N., Zubeidat, K., Saba, Y., Horev, Y., Barel, O., Wilharm, A., Heyman, O., Wald, S., Eli-Berchoer, L., Shapiro, H., Nadler, C., Elinav, E., Wilensky, A., Prinz, I., Bercovier, H. & Hovav, A-H., 10.02.2021, In: CELL HOST MICROBE. 29, 2, p. 197-209.e5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 controls central nervous system autoimmunity through the intestinal microbiome
Regen, T., Isaac, S., Amorim, A., Núñez, N. G., Hauptmann, J., Shanmugavadivu, A., Klein, M., Sankowski, R., Mufazalov, I. A., Yogev, N., Huppert, J., Wanke, F., Witting, M., Grill, A., Gálvez, E. J. C., Nikolaev, A., Blanfeld, M., Prinz, I., Schmitt-Kopplin, P., Strowig, T., Reinhardt, C., Prinz, M., Bopp, T., Becher, B., Ubeda, C. & Waisman, A., 05.02.2021, In: SCI IMMUNOL. 6, 56Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation
Helmke, A., Hüsing, A. M., Gaedcke, S., Brauns, N., Balzer, M. S., Reinhardt, M., Hiss, M., Shushakova, N., de Luca, D., Prinz, I., Haller, H. & von Vietinghoff, S., 02.2021, In: EUR J IMMUNOL. 51, 2, p. 354-367 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance
Wilharm, A., Brigas, H. C., Sandrock, I., Ribeiro, M., Amado, T., Reinhardt, A., Demera, A., Hoenicke, L., Strowig, T., Carvalho, T., Prinz, I. & Ribot, J. C., 01.2021, In: MUCOSAL IMMUNOL. 14, 1, p. 242-252 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer's Patches of Mice
Ullrich, L., Lueder, Y., Juergens, A-L., Wilharm, A., Barros-Martins, J., Bubke, A., Demera, A., Ikuta, K., Patzer, G. E., Janssen, A., Sandrock, I., Prinz, I. & Rampoldi, F., 2021, In: FRONT IMMUNOL. 12, 729607.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Synthetic retinoid AM80 inhibits IL-17 production of gamma delta T cells and ameliorates biliary atresia in mice
Möhn, N., Bruni, E., Schröder, A., Frömmel, S., Gueler, F., Vieten, G., Prinz, I., Kuebler, J. F., Petersen, C. & Klemann, C., 12.2020, In: LIVER INT. 40, 12, p. 3031-3041 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
From basic research to clinical application of γδ T cells
Déchanet-Merville, J. & Prinz, I., 11.2020, In: IMMUNOL REV. 298, 1, p. 5-9 5 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions
Deseke, M. & Prinz, I., 09.2020, In: CELL MOL IMMUNOL. 17, 9, p. 914-924 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection
Klein, S., Ghersi, D., Manns, M. P., Prinz, I., Cornberg, M. & Kraft, A. R. M., 31.08.2020, In: J VIROL. 94, 18, e00795-20.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth
Ravens, S., Fichtner, A. S., Willers, M., Torkornoo, D., Pirr, S., Schöning, J., Deseke, M., Sandrock, I., Bubke, A., Wilharm, A., Dodoo, D., Egyir, B., Flanagan, K. L., Steinbrück, L., Dickinson, P., Ghazal, P., Adu, B., Viemann, D. & Prinz, I., 04.08.2020, In: P NATL ACAD SCI USA. 117, 31, p. 18649-18660 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 regulates DC migration to the peribronchial LNs and allergen presentation in experimental allergic asthma
Jirmo, A. C., Busse, M., Happle, C., Skuljec, J., Dalüge, K., Habener, A., Grychtol, R., DeLuca, D. S., Breiholz, O. D., Prinz, I. & Hansen, G., 07.2020, In: EUR J IMMUNOL. 50, 7, p. 1019-1033 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reappearance of effector T cells is associated with recovery from COVID-19
Odak, I., Barros-Martins, J., Bošnjak, B., Stahl, K., David, S., Wiesner, O., Busch, M., Hoeper, M. M., Pink, I., Welte, T., Cornberg, M., Stoll, M., Goudeva, L., Blasczyk, R., Ganser, A., Prinz, I., Förster, R., Koenecke, C. & Schultze-Florey, C. R., 07.2020, In: EBIOMEDICINE. 57, 102885.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults
Fichtner, A. S., Bubke, A., Rampoldi, F., Tan, L., Wilharm, A., Steinbrück, L., Schultze-Florey, C., von Kaisenberg, C., Prinz, I., Herrmann, T. & Ravens, S., 06.2020, In: J LEUKOCYTE BIOL. 107, 6, p. 1023-1032 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice
Moyé, S., Bormann, T., Maus, R., Sparwasser, T., Sandrock, I., Prinz, I., Warnecke, G., Welte, T., Gauldie, J., Kolb, M. & Maus, U. A., 01.05.2020, In: J IMMUNOL. 204, 9, p. 2429-2438 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development and Function of γδT Cells in the Oral Mucosa
Hovav, A. H., Wilharm, A., Barel, O. & Prinz, I., 05.2020, In: J DENT RES. 99, 5, p. 498-505 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity
Janssen, A., Villacorta Hidalgo, J., Beringer, D. X., van Dooremalen, S., Fernando, F., van Diest, E., Terrizi, A. R., Bronsert, P., Kock, S., Schmitt-Gräff, A., Werner, M., Heise, K., Follo, M., Straetemans, T., Sebestyen, Z., Chudakov, D. M., Kasatskaya, S. A., Frenkel, F. E., Ravens, S., Spierings, E., Prinz, I., Küppers, R., Malkovsky, M., Fisch, P. & Kuball, J., 04.2020, In: CANCER IMMUNOL RES. 8, 4, p. 530-543 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human γδ TCR Repertoires in Health and Disease
Fichtner, A. S., Ravens, S. & Prinz, I., 26.03.2020, In: CELLS-BASEL. 9, 4, 800.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Revisiting the Interaction of γδ T-Cells and B-Cells
Rampoldi, F., Ullrich, L. & Prinz, I., 18.03.2020, In: CELLS-BASEL. 9, 3, 743.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
Sebestyen, Z., Prinz, I., Déchanet-Merville, J., Silva-Santos, B. & Kuball, J., 03.2020, In: NAT REV DRUG DISCOV. 19, 3, p. 169-184 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment
Prinz, I., Sandrock, I. & Mrowietz, U., 06.01.2020, In: J EXP MED. 217, 1Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD
Odak, I., Depkat-Jakob, A., Beck, M., Jarek, M., Yu, Y., Seidler, U., David, S., Ganser, A., Förster, R., Prinz, I. & Koenecke, C., 2020, In: PLOS ONE. 15, 4, e0231222.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer
Mikulak, J., Oriolo, F., Bruni, E., Roberto, A., Colombo, F. S., Villa, A., Bosticardo, M., Bortolomai, I., Lo Presti, E., Meraviglia, S., Dieli, F., Vetrano, S., Danese, S., Della Bella, S., Carvello, M. M., Sacchi, M., Cugini, G., Colombo, G., Klinger, M., Spaggiari, P., Roncalli, M., Prinz, I., Ravens, S., di Lorenzo, B., Marcenaro, E., Silva-Santos, B., Spinelli, A. & Mavilio, D., 19.12.2019, In: JCI INSIGHT. 4, 24Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Focusing of the regulatory T-cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease
Odak, I., Raha, S., Schultze-Florey, C., Tavil, S., Ravens, S., Ganser, A., Förster, R., Prinz, I. & Koenecke, C., 12.2019, In: HAEMATOLOGICA. 104, 12, p. e577-e580Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dangerous γδ T cells in aged mice
Prinz, I. & Sandrock, I., 08.2019, In: EMBO REP. 20, 8, p. e48678Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function
Wilharm, A., Sandrock, I., Marotel, M., Demera, A., Naumann, R., Walzer, T. & Prinz, I., 05.2019, In: EUR J IMMUNOL. 49, 5, p. 686-693 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells
Di Lorenzo, B., Simões, A. E., Caiado, F., Tieppo, P., Correia, D. V., Carvalho, T., da Silva, M. G., Déchanet-Merville, J., Schumacher, T. N., Prinz, I., Norell, H., Ravens, S., Vermijlen, D. & Silva-Santos, B., 04.2019, In: CANCER IMMUNOL RES. 7, 4, p. 552-558 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads
Mangare, C., Tischer-Zimmermann, S., Riese, S. B., Dragon, A. C., Prinz, I., Blasczyk, R., Maecker-Kolhoff, B. & Eiz-Vesper, B., 20.03.2019, In: INT J MOL SCI. 20, 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3
Ronkina, N., Schuster-Gossler, K., Hansmann, F., Kunze-Schumacher, H., Sandrock, I., Yakovleva, T., Lafera, J., Baumgärtner, W., Krueger, A., Prinz, I., Gossler, A., Kotlyarov, A. & Gaestel, M., 15.03.2019, In: MOL CELL BIOL. 39, 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation
Sparber, F., De Gregorio, C., Steckholzer, S., Ferreira, F. M., Dolowschiak, T., Ruchti, F., Kirchner, F. R., Mertens, S., Prinz, I., Joller, N., Buch, T., Glatz, M., Sallusto, F. & LeibundGut-Landmann, S., 13.03.2019, In: CELL HOST MICROBE. 25, 3, p. 389-403.e6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity
Łyszkiewicz, M., Winter, S. J., Witzlau, K., Föhse, L., Brownlie, R., Puchałka, J., Verheyden, N. A., Kunze-Schumacher, H., Imelmann, E., Blume, J., Raha, S., Sekiya, T., Yoshimura, A., Frueh, J. T., Ullrich, E., Huehn, J., Weiss, S., Gutierrez, M. G., Prinz, I., Zamoyska, R., Ziętara, N. & Krueger, A., 03.2019, In: PLOS BIOL. 17, 3, p. e2006716Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis
Wilharm, A., Tabib, Y., Nassar, M., Reinhardt, A., Mizraji, G., Sandrock, I., Heyman, O., Barros-Martins, J., Aizenbud, Y., Khalaileh, A., Eli-Berchoer, L., Elinav, E., Wilensky, A., Förster, R., Bercovier, H., Prinz, I. & Hovav, A-H., 12.02.2019, In: P NATL ACAD SCI USA. 116, 7, p. 2652-2661 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy
Soon, C. F., Zhang, S., Suneetha, P. V., Antunes, D. A., Manns, M. P., Raha, S., Schultze-Florey, C., Prinz, I., Wedemeyer, H., Sällberg Chen, M. & Cornberg, M., 2019, In: FRONT IMMUNOL. 10, p. 2076Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells
Sandrock, I., Reinhardt, A., Ravens, S., Binz, C., Wilharm, A., Martins, J., Oberdörfer, L., Tan, L., Lienenklaus, S., Zhang, B., Naumann, R., Zhuang, Y., Krueger, A., Förster, R. & Prinz, I., 03.12.2018, In: J EXP MED. 215, 12, p. 3006-3018 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pathogenic TH17 inflammation is sustained in the lungs by conventional dendritic cells and Toll-like receptor 4 signaling
Shalaby, K. H., Lyons-Cohen, M. R., Whitehead, G. S., Thomas, S. Y., Prinz, I., Nakano, H. & Cook, D. N., 10.2018, In: J ALLERGY CLIN IMMUN. 142, 4, p. 1229-1242.e6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells
Lessel, D., Gehbauer, C., Bramswig, N. C., Schluth-Bolard, C., Venkataramanappa, S., van Gassen, K. L. I., Hempel, M., Haack, T. B., Baresic, A., Genetti, C. A., Funari, M. F. A., Lessel, I., Kuhlmann, L., Simon, R., Liu, P., Denecke, J., Kuechler, A., de Kruijff, I., Shoukier, M., Lek, M., Mullen, T., Lüdecke, H-J., Lerario, A. M., Kobbe, R., Krieger, T., Demeer, B., Lebrun, M., Keren, B., Nava, C., Buratti, J., Afenjar, A., Shinawi, M., Guillen Sacoto, M. J., Gauthier, J., Hamdan, F. F., Laberge, A-M., Campeau, P. M., Louie, R. J., Cathey, S. S., Prinz, I., Jorge, A. A. L., Terhal, P. A., Lenhard, B., Wieczorek, D., Strom, T. M., Agrawal, P. B., Britsch, S., Tolosa, E. & Kubisch, C., 01.08.2018, In: BRAIN. 141, 8, p. 2299-2311 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17-Mediated Immunity Controls Skin Infection and T Helper 1 Response during Experimental Microsporum canis Dermatophytosis
Burstein, V. L., Guasconi, L., Beccacece, I., Theumer, M. G., Mena, C., Prinz, I., Cervi, L., Herrero, M., Masih, D. T. & Chiapello, L. S., 08.2018, In: J INVEST DERMATOL. 138, 8, p. 1744-1753 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease
Schultze-Florey, R. E., Tischer, S., Kuhlmann, L., Hundsdoerfer, P., Koch, A., Anagnostopoulos, I., Ravens, S., Goudeva, L., Schultze-Florey, C., Koenecke, C., Blasczyk, R., Koehl, U., Heuft, H-G., Prinz, I., Eiz-Vesper, B. & Maecker-Kolhoff, B., 27.06.2018, In: FRONT IMMUNOL. 9, p. 1475Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gegenseitige Beeinflussung von Immunsystem und Knochen
Kamradt, T., Amling, M., Dankbar, B., Dudeck, A., Gunzer, M., Ignatius, A., Krönke, G., Kubatzky, K., Pap, T., Prinz, I., Schett, G., Schinke, T., Tuckermann, J. & Waisman, A., 05.2018, In: Z RHEUMATOL. 77, Suppl 1, p. 8-11 4 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Hammer, Q., Rückert, T., Borst, E. M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I. W., Hofmann, J., Na, I-K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M-F., Messerle, M. & Romagnani, C., 05.2018, In: NAT IMMUNOL. 19, 5, p. 453-463 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The neonatal window of opportunity-early priming for life
Renz, H., Adkins, B. D., Bartfeld, S., Blumberg, R. S., Farber, D. L., Garssen, J., Ghazal, P., Hackam, D. J., Marsland, B. J., McCoy, K. D., Penders, J., Prinz, I., Verhasselt, V., von Mutius, E., Weiser, J. N., Wesemann, D. R. & Hornef, M. W., 04.2018, In: J ALLERGY CLIN IMMUN. 141, 4, p. 1212-1214 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Whodunit? The Contribution of Interleukin (IL)-17/IL-22-Producing γδ T Cells, αβ T Cells, and Innate Lymphoid Cells to the Pathogenesis of Spondyloarthritis
Reinhardt, A. & Prinz, I., 04.2018, In: FRONT IMMUNOL. 9, p. 885Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy
Ravens, S., Hengst, J., Schlapphoff, V., Deterding, K., Dhingra, A., Schultze-Florey, C., Koenecke, C., Cornberg, M., Wedemeyer, H. & Prinz, I., 16.03.2018, In: FRONT IMMUNOL. 9, p. 510Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases
Papotto, P. H., Reinhardt, A., Prinz, I. & Silva-Santos, B., 02.2018, In: J AUTOIMMUN. 87, p. 26-37 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2017
IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation
Alnahas, S., Hagner, S., Raifer, H., Kilic, A., Gasteiger, G., Mutters, R., Hellhund, A., Prinz, I., Pinkenburg, O., Visekruna, A., Garn, H. & Steinhoff, U., 14.11.2017, In: FRONT IMMUNOL. 8, p. 1562Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection
Pezoldt, J., Pisano, F., Heine, W., Pasztoi, M., Rosenheinrich, M., Nuss, A. M., Pils, M. C., Prinz, I., Förster, R., Huehn, J. & Dersch, P., 15.09.2017, In: J INFECT DIS. 216, 6, p. 752-760 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7
Vachharajani, N., Joeris, T., Luu, M., Hartmann, S., Pautz, S., Jenike, E., Pantazis, G., Prinz, I., Hofer, M. J., Steinhoff, U. & Visekruna, A., 01.08.2017, In: ONCOTARGET. 8, 31, p. 50447-50459 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke
Arunachalam, P., Ludewig, P., Melich, P., Arumugam, T. V., Gerloff, C., Prinz, I., Magnus, T. & Gelderblom, M., 07.2017, In: STROKE. 48, 7, p. 1957-1965 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutrophilic NLRP3 inflammasome-dependent IL-1β secretion regulates the γδT17 cell response in respiratory bacterial infections
Hassane, M., Demon, D., Soulard, D., Fontaine, J., Keller, L. E., Patin, E. C., Porte, R., Prinz, I., Ryffel, B., Kadioglu, A., Veening, J-W., Sirard, J-C., Faveeuw, C., Lamkanfi, M., Trottein, F. & Paget, C., 07.2017, In: MUCOSAL IMMUNOL. 10, 4, p. 1056-1068 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability
Edelblum, K. L., Sharon, G., Singh, G., Odenwald, M. A., Sailer, A., Cao, S., Ravens, S., Thomsen, I., El Bissati, K., McLeod, R., Dong, C., Gurbuxani, S., Prinz, I., Mazmanian, S. K. & Turner, J. R., 10.06.2017, In: CELL MOL GASTROENTER. 4, 2, p. 285-297 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Eomes expression reports the progressive differentiation of IFN-γ-producing Th1-like γδ T cells
Lino, C. N. R., Barros-Martins, J., Oberdörfer, L., Walzer, T. & Prinz, I., 06.2017, In: EUR J IMMUNOL. 47, 6, p. 970-981 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply to Comment : Could γ/δ T Cells Explain Adverse Effects of Zoledronic Acid? Comment on the Article by Reinhardt et al. 2016
Reinhardt, A. & Prinz, I., 06.2017, In: ARTHRITIS RHEUMATOL. 69, 6, p. 1339-1341 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection
Ravens, S., Schultze-Florey, C., Raha, S., Sandrock, I., Drenker, M., Oberdörfer, L., Reinhardt, A., Ravens, I., Beck, M., Geffers, R., von Kaisenberg, C., Heuser, M., Thol, F., Ganser, A., Förster, R., Koenecke, C. & Prinz, I., 04.2017, In: NAT IMMUNOL. 18, 4, p. 393-401 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Interleukin-23-Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice
Reinhardt, A., Yevsa, T., Worbs, T., Lienenklaus, S., Sandrock, I., Oberdörfer, L., Korn, T., Weiss, S., Förster, R. & Prinz, I., 10.2016, In: ARTHRITIS RHEUMATOL. 68, 10, p. 2476-86 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease
Raha, S., Raud, B., Oberdörfer, L., Castro, C. N., Schreder, A., Freitag, J., Longerich, T., Lochner, M., Sparwasser, T., Berod, L., Koenecke, C. & Prinz, I., 09.2016, In: EUR J IMMUNOL. 46, 9, p. 2233-8 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brief Report: Arthritis in KRN T Cell Receptor-Transgenic Mice Does Not Require Interleukin-17 or Th17 Cells
Auger, J. L., Cowan, H. M., Engelson, B. J., Kashem, S. W., Prinz, I. & Binstadt, B. A., 08.2016, In: ARTHRITIS RHEUMATOL. 68, 8, p. 1849-55 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
Yang, B-H., Hagemann, S., Mamareli, P., Lauer, U., Hoffmann, U., Beckstette, M., Föhse, L., Prinz, I., Pezoldt, J., Suerbaum, S., Sparwasser, T., Hamann, A., Floess, S., Huehn, J. & Lochner, M., 03.2016, In: MUCOSAL IMMUNOL. 9, 2, p. 444-57 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 is not essential for inflammation and chronic pelvic pain development in an experimental model of chronic prostatitis/chronic pelvic pain syndrome
Motrich, R. D., Breser, M. L., Sánchez, L. R., Godoy, G. J., Prinz, I. & Rivero, V. E., 03.2016, In: PAIN. 157, 3, p. 585-597 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients
Klemann, C., Schröder, A., Dreier, A., Möhn, N., Dippel, S., Winterberg, T., Wilde, A., Yu, Y., Thorenz, A., Gueler, F., Jörns, A., Tolosa, E., Leonhardt, J., Haas, J. D., Prinz, I., Vieten, G., Petersen, C. & Kuebler, J. F., 01.2016, In: GASTROENTEROLOGY. 150, 1, p. 229-241.e5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development
Sandrock, I., Ziętara, N., Łyszkiewicz, M., Oberdörfer, L., Witzlau, K., Krueger, A. & Prinz, I., 16.12.2015, In: PLOS ONE. 10, 12, p. e0145010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells come to stay: Innate skin memory in the Aldara model
Prinz, I. & Sandrock, I., 11.2015, In: EUR J IMMUNOL. 45, 11, p. 2994-7 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multicongenic fate mapping quantification of dynamics of thymus colonization
Ziętara, N., Łyszkiewicz, M., Puchałka, J., Witzlau, K., Reinhardt, A., Förster, R., Pabst, O., Prinz, I. & Krueger, A., 21.09.2015, In: J EXP MED. 212, 10, p. 1589-601 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis
Schwinge, D., Carambia, A., Quaas, A., Krech, T., Wegscheid, C., Tiegs, G., Prinz, I., Lohse, A. W., Herkel, J. & Schramm, C., 15.03.2015, In: J IMMUNOL. 194, 6, p. 2522-30 9 p.Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset
Kashani, E., Föhse, L., Raha, S., Sandrock, I., Oberdörfer, L., Koenecke, C., Suerbaum, S., Weiss, S. & Prinz, I., 13.03.2015, In: NAT COMMUN. 6, p. 6477Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors
Łyszkiewicz, M., Ziętara, N., Föhse, L., Puchałka, J., Diestelhorst, J., Witzlau, K., Prinz, I., Schambach, A. & Krueger, A., 15.01.2015, In: BLOOD. 125, 3, p. 457-64 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others
Vermijlen, D. & Prinz, I., 10.10.2014, In: FRONT IMMUNOL. 5, p. 486Research output: SCORING: Contribution to journal › SCORING: Review article › Research
γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitis
Blink, S. E., Caldis, M. W., Goings, G. E., Harp, C. T., Malissen, B., Prinz, I., Xu, D. & Miller, S. D., 07.2014, In: CELL IMMUNOL. 290, 1, p. 39-51 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Visualization and quantification of monoallelic TCRα gene rearrangement in αβ T cells
Winter, M., Kashani, E., Chennupati, V., Föhse, L. & Prinz, I., 06.2014, In: IMMUNOL CELL BIOL. 92, 5, p. 409-16 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR7-mediated migration in the thymus controls γδ T-cell development
Reinhardt, A., Ravens, S., Fleige, H., Haas, J. D., Oberdörfer, L., Łyszkiewicz, M., Förster, R. & Prinz, I., 05.2014, In: EUR J IMMUNOL. 44, 5, p. 1320-9 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
Fleige, H., Ravens, S., Moschovakis, G. L., Bölter, J., Willenzon, S., Sutter, G., Häussler, S., Kalinke, U., Prinz, I. & Förster, R., 07.04.2014, In: J EXP MED. 211, 4, p. 643-51 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
Daussy, C., Faure, F., Mayol, K., Viel, S., Gasteiger, G., Charrier, E., Bienvenu, J., Henry, T., Debien, E., Hasan, U. A., Marvel, J., Yoh, K., Takahashi, S., Prinz, I., de Bernard, S., Buffat, L. & Walzer, T., 10.03.2014, In: J EXP MED. 211, 3, p. 563-77 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis
Hammerich, L., Bangen, J. M., Govaere, O., Zimmermann, H. W., Gassler, N., Huss, S., Liedtke, C., Prinz, I., Lira, S. A., Luedde, T., Roskams, T., Trautwein, C., Heymann, F. & Tacke, F., 02.2014, In: HEPATOLOGY. 59, 2, p. 630-42 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induced and thymus-derived Foxp3⁺ regulatory T cells share a common niche
Huang, Y-J., Haist, V., Baumgärtner, W., Föhse, L., Prinz, I., Suerbaum, S., Floess, S. & Huehn, J., 02.2014, In: EUR J IMMUNOL. 44, 2, p. 460-8 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Differential postselection proliferation dynamics of αβ T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling
Föhse, L., Reinhardt, A., Oberdörfer, L., Schmitz, S., Förster, R., Malissen, B. & Prinz, I., 01.09.2013, In: J IMMUNOL. 191, 5, p. 2384-92 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional development of γδ T cells
Prinz, I., Silva-Santos, B. & Pennington, D. J., 08.2013, In: EUR J IMMUNOL. 43, 8, p. 1988-94 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Donor Vδ1+ γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL
Prinz, I., Thamm, K., Port, M., Weissinger, E. M., Stadler, M., Gabaev, I., Jacobs, R., Ganser, A. & Koenecke, C., 11.05.2013, In: EXP HEMATOL ONCOL. 2, 1, p. 14Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells
Ziętara, N., Łyszkiewicz, M., Witzlau, K., Naumann, R., Hurwitz, R., Langemeier, J., Bohne, J., Sandrock, I., Ballmaier, M., Weiss, S., Prinz, I. & Krueger, A., 30.04.2013, In: P NATL ACAD SCI USA. 110, 18, p. 7407-12 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The natural and the inducible interleukin (IL)-17-producing γδ T cells
Chien, Y., Zeng, X. & Prinz, I., 04.2013, In: TRENDS IMMUNOL. 34, 4, p. 151-4 4 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2012
Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave
Haas, J. D., Ravens, S., Düber, S., Sandrock, I., Oberdörfer, L., Kashani, E., Chennupati, V., Föhse, L., Naumann, R., Weiss, S., Krueger, A., Förster, R. & Prinz, I., 27.07.2012, In: IMMUNITY. 37, 1, p. 48-59 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapeutic potential of induced and natural FoxP3(+) regulatory T cells for the treatment of Graft-versus-host disease
Prinz, I. & Koenecke, C., 06.2012, In: ARCH IMMUNOL THER EX. 60, 3, p. 183-90 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Dynamic migration of γδ intraepithelial lymphocytes requires occludin
Edelblum, K. L., Shen, L., Weber, C. R., Marchiando, A. M., Clay, B. S., Wang, Y., Prinz, I., Malissen, B., Sperling, A. I. & Turner, J. R., 01.05.2012, In: P NATL ACAD SCI USA. 109, 18, p. 7097-102 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells are not alone
Prinz, I. & Föhse, L., 04.2012, In: IMMUNOL CELL BIOL. 90, 4, p. 370-1 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
Lindner, C., Wahl, B., Föhse, L., Suerbaum, S., Macpherson, A. J., Prinz, I. & Pabst, O., 13.02.2012, In: J EXP MED. 209, 2, p. 365-77 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo
Moschovakis, G. L., Bubke, A., Dittrich-Breiholz, O., Braun, A., Prinz, I., Kremmer, E. & Förster, R., 01.2012, In: EUR J IMMUNOL. 42, 1, p. 48-57 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction of BALT in the absence of IL-17
Fleige, H., Haas, J. D., Stahl, F. R., Willenzon, S., Prinz, I. & Förster, R., 01.2012, In: NAT IMMUNOL. 13, 1, p. 1; author reply 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease.
Koenecke, C., Lee, C-W., Thamm, K., Föhse, L., Schafferus, M., Mittrücker, H. W., Floess, S., Huehn, J., Ganser, A., Förster, R. & Prinz, I., 2012, In: J IMMUNOL. 189, 6, p. 2890-2896 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner, J. E., Krebs, C., Tittel, A. P., Paust, H-J., Meyer-Schwesinger, C., Bennstein, S. B., Steinmetz, O., Prinz, I., Magnus, T., Korn, T., Stahl, R. A. K., Kurts, C. & Panzer, U., 2012, In: J AM SOC NEPHROL. 23, 9, p. 1486-1495 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Shift of graft-versus-host-disease target organ tropism by dietary vitamin A
Koenecke, C., Prinz, I., Bubke, A., Schreder, A., Lee, C-W., Pabst, O. & Förster, R., 2012, In: PLOS ONE. 7, 5, p. e38252Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells
Föhse, L., Suffner, J., Suhre, K., Wahl, B., Lindner, C., Lee, C-W., Schmitz, S., Haas, J. D., Lamprecht, S., Koenecke, C., Bleich, A., Hämmerling, G. J., Malissen, B., Suerbaum, S., Förster, R. & Prinz, I., 11.2011, In: EUR J IMMUNOL. 41, 11, p. 3101-13 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Commensal gut flora reduces susceptibility to experimentally induced colitis via T-cell-derived interleukin-10
Pils, M. C., Bleich, A., Prinz, I., Fasnacht, N., Bollati-Fogolin, M., Schippers, A., Rozell, B. & Müller, W., 10.2011, In: INFLAMM BOWEL DIS. 17, 10, p. 2038-46 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamics of the interaction of γδ T cells with their neighbors in vivo
Prinz, I., 07.2011, In: CELL MOL LIFE SCI. 68, 14, p. 2391-8 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection
Busche, A., Schmitz, S., Fleige, H., Robbins, S. H., Walzer, T., Stewart, C. A., Förster, R., Messerle, M. & Prinz, I., 01.03.2011, In: J IMMUNOL. 186, 5, p. 2918-25 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells
Haas, J. D., Nistala, K., Petermann, F., Saran, N., Chennupati, V., Schmitz, S., Korn, T., Wedderburn, L. R., Förster, R., Krueger, A. & Prinz, I., 2011, In: PLOS ONE. 6, 5, p. e20171Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo
Malinarich, F. H., Grabski, E., Worbs, T., Chennupati, V., Haas, J. D., Schmitz, S., Candia, E., Quera, R., Malissen, B., Förster, R., Hermoso, M. & Prinz, I., 12.2010, In: EUR J IMMUNOL. 40, 12, p. 3378-88 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review