Prof.Dr.rer.nat ID: 15692247
Immo Prinz
Publications
- 2016
Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients
Klemann, C., Schröder, A., Dreier, A., Möhn, N., Dippel, S., Winterberg, T., Wilde, A., Yu, Y., Thorenz, A., Gueler, F., Jörns, A., Tolosa, E., Leonhardt, J., Haas, J. D., Prinz, I., Vieten, G., Petersen, C. & Kuebler, J. F., 01.2016, In: GASTROENTEROLOGY. 150, 1, p. 229-241.e5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development
Sandrock, I., Ziętara, N., Łyszkiewicz, M., Oberdörfer, L., Witzlau, K., Krueger, A. & Prinz, I., 16.12.2015, In: PLOS ONE. 10, 12, p. e0145010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells come to stay: Innate skin memory in the Aldara model
Prinz, I. & Sandrock, I., 11.2015, In: EUR J IMMUNOL. 45, 11, p. 2994-7 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multicongenic fate mapping quantification of dynamics of thymus colonization
Ziętara, N., Łyszkiewicz, M., Puchałka, J., Witzlau, K., Reinhardt, A., Förster, R., Pabst, O., Prinz, I. & Krueger, A., 21.09.2015, In: J EXP MED. 212, 10, p. 1589-601 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis
Schwinge, D., Carambia, A., Quaas, A., Krech, T., Wegscheid, C., Tiegs, G., Prinz, I., Lohse, A. W., Herkel, J. & Schramm, C., 15.03.2015, In: J IMMUNOL. 194, 6, p. 2522-30 9 p.Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6⁺CD27⁻ subset
Kashani, E., Föhse, L., Raha, S., Sandrock, I., Oberdörfer, L., Koenecke, C., Suerbaum, S., Weiss, S. & Prinz, I., 13.03.2015, In: NAT COMMUN. 6, p. 6477Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors
Łyszkiewicz, M., Ziętara, N., Föhse, L., Puchałka, J., Diestelhorst, J., Witzlau, K., Prinz, I., Schambach, A. & Krueger, A., 15.01.2015, In: BLOOD. 125, 3, p. 457-64 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Ontogeny of Innate T Lymphocytes - Some Innate Lymphocytes are More Innate than Others
Vermijlen, D. & Prinz, I., 10.10.2014, In: FRONT IMMUNOL. 5, p. 486Research output: SCORING: Contribution to journal › SCORING: Review article › Research
γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitis
Blink, S. E., Caldis, M. W., Goings, G. E., Harp, C. T., Malissen, B., Prinz, I., Xu, D. & Miller, S. D., 07.2014, In: CELL IMMUNOL. 290, 1, p. 39-51 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Visualization and quantification of monoallelic TCRα gene rearrangement in αβ T cells
Winter, M., Kashani, E., Chennupati, V., Föhse, L. & Prinz, I., 06.2014, In: IMMUNOL CELL BIOL. 92, 5, p. 409-16 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR7-mediated migration in the thymus controls γδ T-cell development
Reinhardt, A., Ravens, S., Fleige, H., Haas, J. D., Oberdörfer, L., Łyszkiewicz, M., Förster, R. & Prinz, I., 05.2014, In: EUR J IMMUNOL. 44, 5, p. 1320-9 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs
Fleige, H., Ravens, S., Moschovakis, G. L., Bölter, J., Willenzon, S., Sutter, G., Häussler, S., Kalinke, U., Prinz, I. & Förster, R., 07.04.2014, In: J EXP MED. 211, 4, p. 643-51 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
Daussy, C., Faure, F., Mayol, K., Viel, S., Gasteiger, G., Charrier, E., Bienvenu, J., Henry, T., Debien, E., Hasan, U. A., Marvel, J., Yoh, K., Takahashi, S., Prinz, I., de Bernard, S., Buffat, L. & Walzer, T., 10.03.2014, In: J EXP MED. 211, 3, p. 563-77 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis
Hammerich, L., Bangen, J. M., Govaere, O., Zimmermann, H. W., Gassler, N., Huss, S., Liedtke, C., Prinz, I., Lira, S. A., Luedde, T., Roskams, T., Trautwein, C., Heymann, F. & Tacke, F., 02.2014, In: HEPATOLOGY. 59, 2, p. 630-42 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induced and thymus-derived Foxp3⁺ regulatory T cells share a common niche
Huang, Y-J., Haist, V., Baumgärtner, W., Föhse, L., Prinz, I., Suerbaum, S., Floess, S. & Huehn, J., 02.2014, In: EUR J IMMUNOL. 44, 2, p. 460-8 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Differential postselection proliferation dynamics of αβ T cells, Foxp3+ regulatory T cells, and invariant NKT cells monitored by genetic pulse labeling
Föhse, L., Reinhardt, A., Oberdörfer, L., Schmitz, S., Förster, R., Malissen, B. & Prinz, I., 01.09.2013, In: J IMMUNOL. 191, 5, p. 2384-92 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional development of γδ T cells
Prinz, I., Silva-Santos, B. & Pennington, D. J., 08.2013, In: EUR J IMMUNOL. 43, 8, p. 1988-94 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Donor Vδ1+ γδ T cells expand after allogeneic hematopoietic stem cell transplantation and show reactivity against CMV-infected cells but not against progressing B-CLL
Prinz, I., Thamm, K., Port, M., Weissinger, E. M., Stadler, M., Gabaev, I., Jacobs, R., Ganser, A. & Koenecke, C., 11.05.2013, In: EXP HEMATOL ONCOL. 2, 1, p. 14Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells
Ziętara, N., Łyszkiewicz, M., Witzlau, K., Naumann, R., Hurwitz, R., Langemeier, J., Bohne, J., Sandrock, I., Ballmaier, M., Weiss, S., Prinz, I. & Krueger, A., 30.04.2013, In: P NATL ACAD SCI USA. 110, 18, p. 7407-12 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The natural and the inducible interleukin (IL)-17-producing γδ T cells
Chien, Y., Zeng, X. & Prinz, I., 04.2013, In: TRENDS IMMUNOL. 34, 4, p. 151-4 4 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2012
Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave
Haas, J. D., Ravens, S., Düber, S., Sandrock, I., Oberdörfer, L., Kashani, E., Chennupati, V., Föhse, L., Naumann, R., Weiss, S., Krueger, A., Förster, R. & Prinz, I., 27.07.2012, In: IMMUNITY. 37, 1, p. 48-59 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapeutic potential of induced and natural FoxP3(+) regulatory T cells for the treatment of Graft-versus-host disease
Prinz, I. & Koenecke, C., 06.2012, In: ARCH IMMUNOL THER EX. 60, 3, p. 183-90 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Dynamic migration of γδ intraepithelial lymphocytes requires occludin
Edelblum, K. L., Shen, L., Weber, C. R., Marchiando, A. M., Clay, B. S., Wang, Y., Prinz, I., Malissen, B., Sperling, A. I. & Turner, J. R., 01.05.2012, In: P NATL ACAD SCI USA. 109, 18, p. 7097-102 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells are not alone
Prinz, I. & Föhse, L., 04.2012, In: IMMUNOL CELL BIOL. 90, 4, p. 370-1 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine
Lindner, C., Wahl, B., Föhse, L., Suerbaum, S., Macpherson, A. J., Prinz, I. & Pabst, O., 13.02.2012, In: J EXP MED. 209, 2, p. 365-77 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficient CCR7 signaling promotes TH2 polarization and B-cell activation in vivo
Moschovakis, G. L., Bubke, A., Dittrich-Breiholz, O., Braun, A., Prinz, I., Kremmer, E. & Förster, R., 01.2012, In: EUR J IMMUNOL. 42, 1, p. 48-57 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction of BALT in the absence of IL-17
Fleige, H., Haas, J. D., Stahl, F. R., Willenzon, S., Prinz, I. & Förster, R., 01.2012, In: NAT IMMUNOL. 13, 1, p. 1; author reply 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IFN-γ production by allogeneic Foxp3+ regulatory T cells is essential for preventing experimental graft-versus-host disease.
Koenecke, C., Lee, C-W., Thamm, K., Föhse, L., Schafferus, M., Mittrücker, H. W., Floess, S., Huehn, J., Ganser, A., Förster, R. & Prinz, I., 2012, In: J IMMUNOL. 189, 6, p. 2890-2896 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner, J. E., Krebs, C., Tittel, A. P., Paust, H-J., Meyer-Schwesinger, C., Bennstein, S. B., Steinmetz, O., Prinz, I., Magnus, T., Korn, T., Stahl, R. A. K., Kurts, C. & Panzer, U., 2012, In: J AM SOC NEPHROL. 23, 9, p. 1486-1495 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Shift of graft-versus-host-disease target organ tropism by dietary vitamin A
Koenecke, C., Prinz, I., Bubke, A., Schreder, A., Lee, C-W., Pabst, O. & Förster, R., 2012, In: PLOS ONE. 7, 5, p. e38252Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells
Föhse, L., Suffner, J., Suhre, K., Wahl, B., Lindner, C., Lee, C-W., Schmitz, S., Haas, J. D., Lamprecht, S., Koenecke, C., Bleich, A., Hämmerling, G. J., Malissen, B., Suerbaum, S., Förster, R. & Prinz, I., 11.2011, In: EUR J IMMUNOL. 41, 11, p. 3101-13 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Commensal gut flora reduces susceptibility to experimentally induced colitis via T-cell-derived interleukin-10
Pils, M. C., Bleich, A., Prinz, I., Fasnacht, N., Bollati-Fogolin, M., Schippers, A., Rozell, B. & Müller, W., 10.2011, In: INFLAMM BOWEL DIS. 17, 10, p. 2038-46 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamics of the interaction of γδ T cells with their neighbors in vivo
Prinz, I., 07.2011, In: CELL MOL LIFE SCI. 68, 14, p. 2391-8 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Genetic labeling reveals altered turnover and stability of innate lymphocytes in latent mouse cytomegalovirus infection
Busche, A., Schmitz, S., Fleige, H., Robbins, S. H., Walzer, T., Stewart, C. A., Förster, R., Messerle, M. & Prinz, I., 01.03.2011, In: J IMMUNOL. 186, 5, p. 2918-25 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of miRNAs miR-133b and miR-206 in the Il17a/f locus is co-regulated with IL-17 production in αβ and γδ T cells
Haas, J. D., Nistala, K., Petermann, F., Saran, N., Chennupati, V., Schmitz, S., Korn, T., Wedderburn, L. R., Förster, R., Krueger, A. & Prinz, I., 2011, In: PLOS ONE. 6, 5, p. e20171Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo
Malinarich, F. H., Grabski, E., Worbs, T., Chennupati, V., Haas, J. D., Schmitz, S., Candia, E., Quera, R., Malissen, B., Förster, R., Hermoso, M. & Prinz, I., 12.2010, In: EUR J IMMUNOL. 40, 12, p. 3378-88 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review