Prof. Dr. ID: 52993
Martin Horstmann
Publications
- 2011
The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).
Escherich, G., Troeger, A. F., Gobel, U., Graubner, U., Pekrun, A., Jorch, N., Kaspers, G., Zimmermann, M., Zur Stadt, U., Kazemir, K., Pieters, R., Horstmann, M., Denboer, M. L. & Janka-Schaub, G., 2011, In: HAEMATOLOGICA. 96, 6, p. 854-862 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Cooperative study group for childhood acute lymphoblastic leukaemia (COALL): long-term results of trials 82,85,89,92 and 97.
Escherich, G., Horstmann, M. A., Zimmermann, M., Janka-Schaub, G. E. & COALL study group, 01.02.2010, In: LEUKEMIA. 24, 2, p. 298-308 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
Zuurbier, L., Homminga, I., Calvert, V., Te Winkel, M. L., Buijs-Gladdines, J. G. C. A. M., Kooi, C., Smits, W. K., Sonneveld, E., Veerman, A. J. P., Kamps, W. A., Horstmann, M., Petricoin, E. F., Pieters, R. & Meijerink, J. P. P., 2010, In: LEUKEMIA. 24, 12, p. 2014-2022 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.
Den, B., Monique, L., Slegtenhorst, V., Marjon, U., Menezes, D., Renée, X., Cheok, U., Meyling, H., Buijs-Gladdines, U., Jessica, G. C. A. M., Peters, U., Susan, T. C. J. M., Zutven, V., Laura, J. C. M., Beverloo, U., Berna, H., Spek, V. D., Peter, J., Escherich, G., Gaby, U., Horstmann, M., Martin, A., Janka-Schaub, G., Gritta, E., Kamps, U., Willem, A., Evans, U., William, E., Pieters, U. & Rob, U., 01.02.2009, In: LANCET ONCOL. 10, 2, p. 125-134 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
WT1 mutations in T-ALL.
Tosello, V., Mansour, M. R., Barnes, K., Paganin, M., Sulis, M. L., Jenkinson, S., Allen, C. G., Gale, R. E., Linch, D. C., Palomero, T., Real, P., Murty, V., Yao, X., Richards, S. M., Goldstone, A., Rowe, J., Basso, G., Wiernik, P. H., Paietta, E., Pieters, R., Horstmann, M., Meijerink, J. P. P. & Ferrando, A. A., 2009, In: BLOOD. 114, 5, p. 1038-1045 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected].
Bhojwani, D., Kang, H., Menezes, R. X., Yang, W., Sather, H., Moskowitz, N. P., Min, D-J., Potter, J. W., Harvey, R., Hunger, S. P., Seibel, N., Raetz, E. A., Pieters, R., Horstmann, M. A., Relling, M. V., den Boer, M. L., Willman, C. L., Carroll, W. L. & Children's Oncology Group Study, 20.09.2008, In: J CLIN ONCOL. 26, 27, p. 4376-4384 9 p., 27.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.
Van Vlierberghe, P., Homminga, I., Zuurbier, L., Gladdines-Buijs, J., van Wering, E. R., Horstmann, M., Beverloo, H. B., Pieters, R. & Meijerink, J. P. P., 2008, In: LEUKEMIA. 22, 4, p. 762-770 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis.
Balgobind, U., Brian, V., Vlierberghe, V., Pieter, U., van Den, O., Ans, M. W., Beverloo, U., Berna, H., Terlouw-Kromosoeto, U., Joan, N. R., Wering, V., Elisabeth, R., Reinhardt, U., Dirk, U., Horstmann, M., Martin, U., Kaspers, U., Gertjan, J. L., Pieters, U., Rob, U., Zwaan, U., Michel, C., Heuvel-Eibrink, V. D., Marry, M., Meijerink, U. & Jules, P. P., 2008, In: BLOOD. 111, 8, p. 4322-4328 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monoallelic or biallelic LMO2 expression in relation to the LMO2 rearrangement status in pediatric T-cell acute lymphoblastic leukemia.
Van Vlierberghe, P., Beverloo, H. B., Buijs-Gladdines, J., van Wering, E. R., Horstmann, M., Pieters, R. & Meijerink, J. P. P., 2008, In: LEUKEMIA. 22, 7, p. 1434-1437 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.
Pieter, V. V., van Grotel, M., Tchinda, J., Lee, C., Beverloo, H. B., Spek, V. D., Peter, J., Stubbs, A., Cools, J., Nagata, K., Fornerod, M., Horstmann, M., Horstmann, M., Wering, V., Elisabeth, R., Soulier, J., Pieters, R. & Meijerink, J. P. P., 2008, In: BLOOD. 111, 9, p. 4668-4680 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.
Metzner, A., Horstmann, M., Fehse, B., Ortmeyer, G., Niemeyer, C. M., Stocking, C., Mayr, G. W. & Jücker, M., 2007, In: GENE THER. 14, 8, p. 699-703 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.
Grotel, V., Martine, U., Meijerink, U., Jules, P. P., Beverloo, U., Berna, H., Langerak, U., Anton, W., Buys-Gladdines, U., Jessica, G. C. A. M., Schneider, U., Pauline, U., Poulsen, U., Tim, S., Den, B., Monique, L., Horstmann, M., Martin, U., Kamps, U., Willem, A., Veerman, U., Anjo, J. P., Wering, V., Elisabeth, R., Noesel, V., Max, M., Pieters, U. & Rob, U., 01.09.2006, In: HAEMATOLOGICA. 91, 9, p. 1212-1221 10 p., 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative multiplexed profiling of cellular signaling networks using phosphotyrosine-specific DNA-tagged SH2 domains.
Dierck, K., Machida, K., Voigt, A., Thimm, J., Horstmann, M., Fiedler, W., Mayer, B. J. & Nollau, P., 2006, In: NAT METHODS. 3, 9, p. 737-744 8 p., 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2005
Correlation of bFGF expression in renal cell cancer with clinical and histopathological features by tissue microarray analysis and measurement of serum levels
Horstmann, M., Merseburger, A. S., von der Heyde, E., Serth, J., Wegener, G., Mengel, M., Feil, G., Hennenlotter, J., Nagele, U., Anastasiadis, A., Bokemeyer, C., Stenzl, A. & Kuczyk, M., 11.2005, In: J CANCER RES CLIN. 131, 11, p. 715-22 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.
Horstmann, M., Hassenpflug, W-A., Udo, Z. S., Escherich, G., Janka-Schaub, G. & Kabisch, H., 2005, In: HAEMATOLOGICA. 90, 12, p. 1701-1703 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia.
Stam, R. W., Boer, D., Monique, L., Schneider, P., Horstmann, M., Horstmann, M., Beverloo, H. B., van der Voort, E., Valsecchi, M. G., de Lorenzo, P., Sallan, S. E., Armstrong, S. A. & Pieters, R., 2005, In: BLOOD. 106, 7, p. 2484-2490 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
Du, J., Widlund, H. R., Horstmann, M., Ramaswamy, S., Ross, K., Huber, W. E., Nishimura, E. K., Golub, T. R. & Fisher, D. E., 2004, In: CANCER CELL. 6, 6, p. 565-576 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion.
Horstmann, M., Neumaier-Probst, E., Lukacs, Z., Steinfeld, R., Ullrich, K. & Kohlschütter, A., 2003, In: NEUROPEDIATRICS. 34, 5, p. 261-264 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma.
Du, J., Miller, A. J., Widlund, H. R., Horstmann, M., Ramaswamy, S. & Fisher, D. E., 2003, In: AM J PATHOL. 163, 1, p. 333-343 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor
Widlund, H. R., Horstmann, M. A., Price, E. R., Cui, J., Lessnick, S. L., Wu, M., He, X. & Fisher, D. E., 16.09.2002, In: J CELL BIOL. 158, 6, p. 1079-87 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.
McGill, G. G., Horstmann, M., Widlund, H. R., Du, J., Motyckova, G., Nishimura, E. K., Lin, Y-L., Ramaswamy, S., Avery, W., Ding, H-F., Jordan, S. A., Jackson, I. J., Korsmeyer, S. J., Golub, T. R. & Fisher, D. E., 2002, In: CELL. 109, 6, p. 707-718 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term follow-up of allogeneic stem cell transplantation in patients with severe aplastic anemia after conditioning with cyclophosphamide plus antithymocyte globulin.
Kröger, N., Zabelina, T., Renges, H., Krüger, W., Kordes, U., Rischewski, J., Schrum, J., Horstmann, M., Ayuketang Ayuk, F., Erttmann, R., Kabisch, H. & Zander, A. R., 2002, In: ANN HEMATOL. 81, 11, p. 627-631 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family.
Motyckova, G., Weilbaecher, K. N., Horstmann, M., Rieman, D. J., Fisher, D. Z. & Fisher, D. E., 08.05.2001, In: P NATL ACAD SCI USA. 98, 10, p. 5798-5803 6 p., 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.
Wu, M., Hemesath, T. J., Takemoto, C. M., Horstmann, M., Wells, A. G., Price, E. R., Fisher, D. Z. & Fisher, D. E., 2000, In: GENE DEV. 14, 3, p. 301-312 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1999
Improved outcome in haemophagocytic lymphohistiocytosis after bone marrow transplantation from related and unrelated donors: a single-centre experience of 12 patients.
Dürken, M., Horstmann, M., Bieling, P., Erttmann, R., Kabisch, H., Löliger, C., Schneider, E. M., Hellwege, H. H., Krüger, W., Kröger, N., Zander, A. R. & Janka, G. E., 01.09.1999, In: BRIT J HAEMATOL. 106, 4, p. 1052-1058 7 p., 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1998
Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3.
Weilbaecher, K. N., Hershey, C. L., Takemoto, C. M., Horstmann, M., Hemesath, T. J., Tashjian, A. H. & Fisher, D. E., 02.03.1998, In: J EXP MED. 187, 5, p. 775-785 11 p., 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome.
Price, E. R., Horstmann, M., Wells, A. G., Weilbaecher, K. N., Takemoto, C. M., Landis, M. W. & Fisher, D. E., 1998, In: J BIOL CHEM. 273, 49, p. 33042-33047 49.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment and long-term outcome of pineal nongerminomatous germ cell tumors.
Knappe, U. J., Bentele, K. H. P., Horstmann, M. & Herrmann, H. D., 1998, In: PEDIATR NEUROSURG. 28, 5, p. 241-245 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1997
Effects of anti-tal-1 oligodeoxynucleotides in T-ALL cell lines.
Anderegg, B., Horstmann, M. & Kabisch, H., 1997, In: CANCER GENE THER. 4, 2, p. 84-90 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequent reduction or loss of DCC gene expression in human osteosarcoma.
Horstmann, M., Pösl, M., Scholz, R. B., Anderegg, B., Simon, P., Baumgaertl, K., Delling, G. & Kabisch, H., 1997, In: BRIT J CANCER. 75, 9, p. 1309-1317 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission.
Zander, A. R., Berger, C., Kröger, N., Stockshläder, M., Krüger, W., Horstmann, M., Grimm, J., Zeller, W., Kabisch, H., Erttmann, R., Schönrock, P., Kuse, R., Braumann, D., Illiger, H. J., Fiedler, W., de Witt, M., Hossfeld, K. D. & Weh, H. J., 1997, In: CLIN CANCER RES. 3(12 Pt 2), p. 2671-2675Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcription of tal-1, a putative oncogene playing an important role in childhood T-ALL, can be shown in normal peripheral blood cells by a highly sensitive RT-PCR assay.
Anderegg, B., Horstmann, M., Ernst, M. & Kabisch, H., 1997, In: PEDIATR HEMAT ONCOL. 14, 4, p. 349-358 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1996
Early toxicity of intensified conditioning with etoposide combined with total body irradiation/cyclophosphamide or busulfan/cyclophosphamide in children undergoing autologous or allogeneic bone marrow transplantation.
Horstmann, M., Kroschke, G., Stockschläder, M., Betker, R., Krüger, W., Erttmann, R., Kabisch, H. & Zander, A., 1996, In: PEDIATR HEMAT ONCOL. 13, 1, p. 45-53 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fatal outcome of disseminated candidosis after allogeneic bone marrow transplantation under treatment with liposomal and conventional amphotericin-B. A report of 4 cases with determination of the Mic values.
Krüger, W., Sobottka, I., Stockschläder, M., Mross, K., Hoffknecht, M., Rüssmann, B., Horstmann, M., Betker, R. & Zander, A., 1996, In: SCAND J INFECT DIS. 28, 3, p. 313-316 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MLL/ENL fusion in congenital acute lymphoblastic leukemia with a unique t(11;18;19).
Horstmann, M., Argyriou-Tirita, A., Borkhardt, A., Kabisch, H., Kapaun, P., Winkler, K. & Haas, O. A., 1996, In: CANCER GENET-NY. 88, 2, p. 103-109 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Use of cryopreserved bone marrow in unrelated allogeneic transplantation.
Stockschläder, M., Krüger, W., Tom Dieck, A., Horstmann, M., Altnöder, M., Löliger, C., Fiedler, W., Hoffknecht, M., Erttmann, R. & Zander, A., 1996, In: BONE MARROW TRANSPL. 17, 2, p. 197-199 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1995
Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia for marrow transplantation from HLA-matched siblings: preliminary results.
Horstmann, M., Stockschläder, M., Krüger, W., Hoffknecht, M., Betker, R., Kabisch, H. & Zander, A., 01.08.1995, In: ANN HEMATOL. 71, 2, p. 77-81 5 p., 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia transplanted with bone marrow from HLA-identical related donors
Horstmann, M., Stockschläder, M., Kabisch, H. & Zander, A., 01.03.1995, In: BLOOD. 85, 5, p. 1404-5 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Experience with liposomal Amphotericin-B in 60 patients undergoing high-dose therapy and bone marrow or peripheral blood stem cell transplantation.
Krüger, W., Stockschläder, M., Rüssmann, B., Berger, C., Hoffknecht, M., Sobottka, I., Kohlschütter, B., Kroschke, G., Kröger, N. & Horstmann, M., 1995, In: BRIT J HAEMATOL. 91, 3, p. 684-690 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1994
Relapse of MALT lymphoma associated with Helicobacter pylori after antibiotic treatment.
Horstmann, M., Erttmann, R. & Winkler, K., 1994, In: LANCET. 343, 8905, p. 1098-1099 8905.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review