Research ExplorerScientific StaffTill Holsten Publications

Till Holsten

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Publications

  1. 2023

  2. Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics

    Johann, P. D., Altendorf, L., Efremova, E-M., Holsten, T., Steinbügl, M., Nemes, K., Eckhardt, A., Kresbach, C., Bockmayr, M., Koch, A., Haberler, C., Antonelli, M., DeSisto, J., Schuhmann, M. U., Hauser, P., Siebert, R., Bens, S., Kool, M., Green, A. L., Hasselblatt, M., Frühwald, M. C. & Schüller, U., 09.2023, In: ACTA NEUROPATHOL. 146, 3, p. 527-541 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. 2022

  4. ALK inhibition as a salvage therapy for a relapsed unclassifiable sarcomatous CNS tumor with EML4/ALK fusion in an infant

    Holsten, T., Bronsema, A., Sturm, D., Sahm, F., Rutkowski, S., Ulrich, S., Wößmann, W. & Kordes, U. R., 08.2022, In: PEDIATR BLOOD CANCER. 69, 8, e29594.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  5. Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

    Graf, M., Interlandi, M., Moreno, N., Holdhof, D., Göbel, C., Melcher, V., Mertins, J., Albert, T. K., Kastrati, D., Alfert, A., Holsten, T., de Faria, F., Meisterernst, M., Rossig, C., Warmuth-Metz, M., Nowak, J., Meyer Zu Hörste, G., Mayère, C., Nef, S., Johann, P., Frühwald, M. C., Dugas, M., Schüller, U. & Kerl, K., 22.03.2022, In: NAT COMMUN. 13, 1, 1544.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. 2021

  7. Detailed Clinical and Histopathological Description of 8 Cases of Molecularly Defined CNS Neuroblastomas

    Holsten, T., Lubieniecki, F., Spohn, M., Mynarek, M., Bison, B., Löbel, U., Rutkowski, S. & Schüller, U., 01.01.2021, In: J NEUROPATH EXP NEUR. 80, 1, p. 52-59 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Ependymoma relapse goes along with a relatively stable epigenome, but a severely altered tumor morphology

    Yang, D., Holsten, T., Börnigen, D., Frank, S., Mawrin, C., Glatzel, M. & Schüller, U., 01.2021, In: BRAIN PATHOL. 31, 1, p. 33-44 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2020

  10. Pik3ca mutations significantly enhance the growth of Shh medulloblastoma and lead to metastatic tumour growth in a novel mouse model

    Niesen, J., Ohli, J., Sedlacik, J., Dührsen, L., Hellwig, M., Spohn, M., Holsten, T. & Schüller, U., 01.05.2020, In: CANCER LETT. 477, p. 10-18 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. 2018

  12. Germline variants in SMARCB1 and other members of the BAF chromatin-remodeling complex across human disease entities: a meta-analysis

    Holsten, T., Bens, S., Oyen, F., Nemes, K., Hasselblatt, M., Kordes, U., Siebert, R., Frühwald, M. C., Schneppenheim, R. & Schüller, U., 08.2018, In: EUR J HUM GENET. 26, 8, p. 1083-1093 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  13. Group 3 medulloblastoma in a patient with a GYS2 germline mutation and glycogen storage disease 0a

    Holsten, T., Tsiakas, K., Kordes, U., Bison, B., Pietsch, T., Rutkowski, S., Santer, R. & Schüller, U., 03.2018, In: CHILD NERV SYST. 34, 3, p. 581-584 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. 2017

  15. Combined BRD4 and CDK9 inhibition as a new therapeutic approach in malignant rhabdoid tumors

    Moreno, N., Holsten, T., Mertins, J., Zoghbi, A., Johann, P-D., Kool, M., Meisterernst, M. & Kerl, K., 10.2017, In: ONCOTARGET. 8, 49, p. 84986-84995

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  16. Liver transplantation as a potentially lifesaving measure in neuroblastoma stage 4S

    Holsten, T., Schuster, T., Grabhorn, E., Hero, B. & Frühwald, M. C., 02.2017, In: PEDIATR HEMAT ONCOL. 34, 1, p. 17-23 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2014

  18. Arsenic trioxide inhibits tumor cell growth in malignant rhabdoid tumors in vitro and in vivo by targeting overexpressed Gli1

    Kerl, K., Moreno, N., Holsten, T., Ahlfeld, J., Mertins, J., Hotfilder, M., Kool, M., Bartelheim, K., Schleicher, S., Handgretinger, R., Schüller, U., Meisterernst, M. & Frühwald, M. C., 15.08.2014, In: INT J CANCER. 135, 4, p. 989-95 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. 2013

  20. Rhabdoid tumors: clinical approaches and molecular targets for innovative therapy

    Kerl, K., Holsten, T. & Frühwald, M. C., 10.2013, In: PEDIATR HEMAT ONCOL. 30, 7, p. 587-604 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research