Dr.med. ID: 1926843
Susanne Burdak-Rothkamm
Publications
- 2023
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease
Elsesy, M. E., Oh-Hohenhorst, S. J., Oing, C., Eckhardt, A., Burdak-Rothkamm, S., Alawi, M., Müller, C., Schüller, U., Maurer, T., von Amsberg, G., Petersen, C., Rothkamm, K. & Mansour, W. Y., 06.2023, In: MOL ONCOL. 17, 6, p. 1129-1147 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Monitoring very low dose radiation damage in DNA using "field-friendly" biomarkers
Rothkamm, K. & Burdak-Rothkamm, S., 2022, Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment. Wood, M. D., Mothersill, C. E., Tsakanova, G., Cresswell, T. & Woloschak, G. E. (eds.). 1 ed. Dordrecht: Springer, p. 137-151 15 p. (NATO Science for Peace and Security Series A: Chemistry and Biology book series (NAPSA)).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2021
Interplay between DNA replication stress, chromatin dynamics and DNA-damage response for the maintenance of genome stability
Mognato, M., Burdak-Rothkamm, S. & Rothkamm, K., 05.06.2021, In: MUTAT RES-REV MUTAT. 787, 108346.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
DNA Damage Repair Deficiency and Synthetic Lethality for Cancer Treatment
Burdak-Rothkamm, S. & Rothkamm, K., 01.2021, In: TRENDS MOL MED. 27, 1, p. 91-92 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2020
Radiosensitisation and enhanced tumour growth delay of colorectal cancer cells by sustained treatment with trifluridine/tipiracil and X-rays
Rothkamm, K., Christiansen, S., Rieckmann, T., Horn, M., Frenzel, T., Brinker, A., Schumacher, U., Stein, A., Petersen, C. & Burdak-Rothkamm, S., 28.11.2020, In: CANCER LETT. 493, p. 179-188 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA Damage Repair Deficiency in Prostate Cancer
Burdak-Rothkamm, S., Mansour, W. Y. & Rothkamm, K., 11.2020, In: TRENDS CANCER. 6, 11, p. 974-984 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair
Elsesy, M. E., Oh-Hohenhorst, S. J., Löser, A., Oing, C., Mutiara, S., Köcher, S., Meien, S., Zielinski, A., Burdak-Rothkamm, S., Tilki, D., Huland, H., Schwarz, R., Petersen, C., Bokemeyer, C., Rothkamm, K. & Mansour, W. Y., 31.08.2020, In: CANCERS. 12, 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer
Köcher, S., Beyer, B., Lange, T., Nordquist, L., Volquardsen, J., Burdak-Rothkamm, S., Schlomm, T., Petersen, C., Rothkamm, K. & Mansour, W. Y., 01.04.2019, In: INT J CANCER. 144, 7, p. 1685-1696 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Radiation-induced bystander and systemic effects serve as a unifying model system for genotoxic stress responses
Burdak-Rothkamm, S. & Rothkamm, K., 21.11.2018, In: MUTAT RES-REV MUTAT. 778, p. 13-22 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Reduced RBM3 expression is associated with aggressive tumor features in esophageal cancer but not significantly linked to patient outcome
Grupp, K., Hofmann, B., Kutup, A., Bachmann, K., Bogoevski, D., Melling, N., Uzunoglu, F. G., El Gammal, A. T., Koop, C., Simon, R., Steurer, S., Krech, T., Burdak-Rothkamm, S., Jacobsen, F., Sauter, G., Izbicki, J. & Wilczak, W., 12.11.2018, In: BMC CANCER. 18, 1, p. 1106Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Establishment of the First Well-differentiated Human Pancreatic Neuroendocrine Tumor Model
Benten, D., Behrang, Y., Unrau, L., Weissmann, V., Wolters-Eisfeld, G., Burdak-Rothkamm, S., Stahl, F. R., Anlauf, M., Grabowski, P., Möbs, M., Dieckhoff, J., Sipos, B., Fahl, M., Eggers, C., Perez, D., Bockhorn, M., Izbicki, J. R., Lohse, A. W. & Schrader, J., 01.03.2018, In: MOL CANCER RES. 16, 3, p. 496-507 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
High-Level Glyoxalase 1 (GLO1) expression is linked to poor prognosis in prostate cancer
Burdelski, C., Shihada, R., Hinsch, A., Angerer, A., Göbel, C., Friedrich, E., Hube-Magg, C., Burdak-Rothkamm, S., Kluth, M., Simon, R., Möller-Koop, C., Sauter, G., Büscheck, F., Wittmer, C., Clauditz, T. S., Krech, T., Tsourlakis, M. C., Minner, S., Graefen, M., Schlomm, T., Wilczak, W. & Jacobsen, F., 11.2017, In: PROSTATE. 77, 15, p. 1528-1538 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevalence of βIII-tubulin (TUBB3) expression in human normal tissues and cancers
Person, F., Wilczak, W., Hube-Magg, C., Burdelski, C., Möller-Koop, C., Simon, R., Noriega, M., Sauter, G., Steurer, S., Burdak-Rothkamm, S. & Jacobsen, F., 10.2017, In: TUMOR BIOL. 39, 10, p. 1010428317712166Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased ERCC1 expression is linked to chromosomal aberrations and adverse tumor biology in prostate cancer
Jacobsen, F., Taskin, B., Melling, N., Sauer, C., Wittmer, C., Hube-Magg, C., Kluth, M., Simon, R., Pehrke, D., Beyer, B., Steuber, T., Thederan, I., Sauter, G., Schlomm, T., Wilczak, W., Möller, K., Weidemann, S. A. & Burdak-Rothkamm, S., 26.07.2017, In: BMC CANCER. 17, 1, p. 504Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Successful mTOR inhibitor therapy for a metastastic neuroendocrine tumour in a patient with a germline TSC2 mutation
Schrader, J., Henes, F. O., Perez, D., Burdak-Rothkamm, S., Stein, A., Izbicki, J. R. & Lohse, A. W., 01.04.2017, In: ANN ONCOL. 28, 4, p. 904-905Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2016
Targeted nanoparticles for tumour radiotherapy enhancement - the long dawn of a golden era?
Gargioni, E., Schulz, F., Raabe, A., Burdak-Rothkamm, S., Rieckmann, T. & Rothkamm, K., 12.2016, In: ANN TRANSL MED. 4, 24, p. 523Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells
Burdak-Rothkamm, S., Rothkamm, K., McClelland, K., Al Rashid, S. T. & Prise, K. M., 28.01.2015, In: CANCER LETT. 356, 2 Pt B, p. 454-61 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
FGFR1 Amplification Is Often Homogeneous and Strongly Linked to the Squamous Cell Carcinoma Subtype in Esophageal Carcinoma
Loga, K., Kohlhaussen, J., Burkhardt, L., Simon, R., Steurer, S., Burdak-Rothkamm, S., Jacobsen, F., Sauter, G. & Krech, T., 2015, In: PLOS ONE. 10, 11, p. e0141867Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Ionizing radiation-induced DNA strand breaks and γ-H2AXγ-H2AX foci in cells exposed to nitric oxide
Rothkamm, K. & Burdak-Rothkamm, S., 2011, In: Methods Mol Biol. 704, p. 17-25 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
Bauerschmidt, C., Arrichiello, C., Burdak-Rothkamm, S., Woodcock, M., Hill, M. A., Stevens, D. L. & Rothkamm, K., 01.2010, In: NUCLEIC ACIDS RES. 38, 2, p. 477-87 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
New molecular targets in radiotherapy: DNA damage signalling and repair in targeted and non-targeted cells
Burdak-Rothkamm, S. & Prise, K. M., 25.12.2009, In: EUR J PHARMACOL. 625, 1-3, p. 151-5 5 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
DNA and chromosomal damage in response to intermittent extremely low-frequency magnetic fields
Burdak-Rothkamm, S., Rothkamm, K., Folkard, M., Patel, G., Hone, P., Lloyd, D., Ainsbury, L. & Prise, K. M., 31.01.2009, In: MUTAT RES-FUND MOL M. 672, 2, p. 82-9 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Oral polio vaccination leads to oligoclonal expansion of TCRBV16+ and TCRBV13+ T cells in the colon of rhesus macaques
Hörer, S., Burdak-Rothkamm, S., Allers, K., Schneider, T. & Duchmann, R., 12.2008, In: EXP MOL PATHOL. 85, 3, p. 189-95 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ATM acts downstream of ATR in the DNA damage response signaling of bystander cells
Burdak-Rothkamm, S., Rothkamm, K. & Prise, K. M., 01.09.2008, In: CANCER RES. 68, 17, p. 7059-65 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Cytoplasmic irradiation induces mitochondrial-dependent 53BP1 protein relocalization in irradiated and bystander cells
Tartier, L., Gilchrist, S., Burdak-Rothkamm, S., Folkard, M. & Prise, K. M., 15.06.2007, In: CANCER RES. 67, 12, p. 5872-9 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ATR-dependent radiation-induced gamma H2AX foci in bystander primary human astrocytes and glioma cells
Burdak-Rothkamm, S., Short, S. C., Folkard, M., Rothkamm, K. & Prise, K. M., 15.02.2007, In: ONCOGENE. 26, 7, p. 993-1002 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2005
Radiosensitivity of tumor cell lines after pretreatment with the EGFR tyrosine kinase inhibitor ZD1839 (Iressa)
Burdak-Rothkamm, S., Rübe, C. E., Nguyen, T. P., Ludwig, D., Feldmann, K., Wiegel, T. & Rübe, C., 03.2005, In: STRAHLENTHER ONKOL. 181, 3, p. 197-204 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
Irradiation induces a biphasic expression of pro-inflammatory cytokines in the lung
Rübe, C. E., Wilfert, F., Palm, J., König, J., Burdak-Rothkamm, S., Liu, L., Schuck, A., Willich, N. & Rübe, C., 07.2004, In: STRAHLENTHER ONKOL. 180, 7, p. 442-8 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review