Dr.med. ID: 50371

Ralf Oheim

graph of relations

Publications

  1. 2024
  2. Patient experiences of interprofessional collaboration and intersectoral communication in rare disease healthcare in Germany - a mixed-methods study

    Inhestern, L., Otto, R., Brandt, M., Zybarth, D., Oheim, R., Schüler, H., Mir, T. S., Tsiakas, K., Dibaj, P., Zschüntzsch, J., Okun, P. M., Hegenbart, U., Sommerburg, O., Schramm, C., Weiler-Normann, C., Härter, M. & Bergelt, C., 13.05.2024, In: ORPHANET J RARE DIS. 19, 1, p. 197

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Hereditary hypophosphatemic rickets with hypercalciuria (HHRH), a complex disorder in need of precision medicine

    Schinke, T. & Oheim, R., 05.2024, In: KIDNEY INT. 105, 5, p. 927-929 3 p.

    Research output: SCORING: Contribution to journalComment/debateResearch

  4. Approaching virtual osteoid volume estimation and in-depth tissue characterization in patients with tumor-induced Osteomalacia

    Schmidt, F. N., Delsmann, J., Yazigi, B., Beil, F. T., Amling, M. & Oheim, R., 22.03.2024, In: J BONE MINER RES. 39, 2, p. 116-129 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. 2023
  6. Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study

    Bartosik, M., Simon, A., Strahl, A., Oheim, R., Amling, M. & Schmidt, F. N., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 597-608 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Epidemiology of Tumor-Induced Osteomalacia in Germany Based on Real World Data

    May, M., Oheim, R., Bovy, L., Doess, A., Maessen, D., Neukirch, B., Norris, R., Williams, A. & Abrahamsen, B., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 630-639 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Empfehlungen zur Versorgung von Patient:innen mit FOP

    Seefried, L., Banholzer, D., Fischer, R., Grafe, I., Hüning, I., Morhart, R., Oheim, R., Semler, O., Siggelkow, H., Stockklausner, C. & Hoyer-Kuhn, H., 11.2023, In: ORTHOPADIE. 52, 11, p. 924-930 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  9. AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia

    Terhal, P., Venhuizen, A. J., Lessel, D., Tan, W-H., Alswaid, A., Grün, R., Alzaidan, H. I., von Kroge, S., Ragab, N., Hempel, M., Kubisch, C., Novais, E., Cristobal, A., Tripolszki, K., Bauer, P., Fischer-Zirnsak, B., Nievelstein, R. A. J., van Dijk, A., Nikkels, P., Oheim, R., Hahn, H., Bertoli-Avella, A., Maurice, M. M. & Kornak, U., 07.09.2023, In: AM J HUM GENET. 110, 9, p. 1470-1481 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. TMCO3, a Putative K+ :Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans

    Holling, T., Brylka, L. J., Scholz, T., Bierhals, T., Herget, T., Meinecke, P., Schinke, T., Oheim, R. & Kutsche, K., 09.2023, In: J BONE MINER RES. 38, 9, p. 1334-1349 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Bone mineral density and microarchitecture change during skeletal growth in harbor seals (Phoca vitulina) from the German coast

    Delsmann, J., Schmidt, B., Oheim, R., Amling, M., Rolvien, T. & Siebert, U., 03.05.2023, In: SCI REP-UK. 13, 1, 7196.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. 2022
  13. Beneficial effects of denosumab on muscle performance in patients with low BMD: a retrospective, propensity score-matched study

    Rupp, T., von Vopelius, E., Strahl, A., Oheim, R., Barvencik, F., Amling, M. & Rolvien, T., 10.2022, In: OSTEOPOROSIS INT. 33, 10, p. 2177-2184 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Catalysis-independent ENPP1 protein signaling regulates mammalian bone mass

    Zimmerman, K., Li, X., von Kroge, S., Stabach, P., Lester, E. R., Chu, E. Y., Srivastava, S., Somerman, M. J., Tommasini, S. M., Busse, B., Schinke, T., Carpenter, T. O., Oheim, R. & Braddock, D. T., 09.2022, In: J BONE MINER RES. 37, 9, p. 1733-1749 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Clinical spectrum of Hereditary Hypophosphatemic rickets with Hypercalciuria (HHRH)

    Stürznickel, J., Heider, F., Delsmann, A., Gödel, M., Grünhagen, J., Huber, T. B., Kornak, U., Amling, M. & Oheim, R., 08.2022, In: J BONE MINER RES. 37, 8, p. 1580-1591 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Characterization of hearing-impairment in Generalized Arterial Calcification of Infancy (GACI)

    Theng, E. H., Brewer, C. C., Oheim, R., Zalewski, C. K., King, K. A., Delsmann, M. M., Rolvien, T., Gafni, R. I., Braddock, D. T., Jeffrey Kim, H. & Ferreira, C. R., 19.07.2022, In: ORPHANET J RARE DIS. 17, 1, 273.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Genetic Diagnostics in Routine Osteological Assessment of Adult Low Bone Mass Disorders

    Oheim, R., Tsourdi, E., Seefried, L., Beller, G., Schubach, M., Vettorazzi, E., Stürznickel, J., Rolvien, T., Ehmke, N., Delsmann, A., Genest, F., Krüger, U., Zemojtel, T., Barvencik, F., Schinke, T., Jakob, F., Hofbauer, L. C., Mundlos, S. & Kornak, U., 16.06.2022, In: J CLIN ENDOCR METAB. 107, 7, p. e3048-e3057

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Tumorlokalisation und Therapie der onkogenen Osteomalazie

    Beil, F. T., Stürznickel, J., Rolvien, T., Amling, M. & Oheim, R., 04.2022, In: Z RHEUMATOL. 81, 3, p. 182-188 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  19. Blast injury on harbour porpoises (Phocoena phocoena) from the Baltic Sea after explosions of deposits of World War II ammunition

    Siebert, U., Stürznickel, J., Schaffeld, T., Oheim, R., Rolvien, T., Prenger-Berninghoff, E., Wohlsein, P., Lakemeyer, J., Rohner, S., Aroha Schick, L., Gross, S., Nachtsheim, D., Ewers, C., Becher, P., Amling, M. & Morell, M., 15.01.2022, In: ENVIRON INT. 159, 107014.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. 2021
  21. Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) due to ENPP1-deficiency

    Höppner, J., Kornak, U., Sinningen, K., Rutsch, F., Oheim, R. & Grasemann, C., 12.2021, In: BONE. 153, 116111.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  22. Conductive hearing loss in the Hyp mouse model of X-linked hypophosphatemia is accompanied by hypomineralization of the auditory ossicles

    Delsmann, M. M., Seist, R., Stürznickel, J., Schmidt, F. N., Mansour, A., Kobelski, M. M., Broocks, G., Peichl, J., Oheim, R., Praetorius, M., Schinke, T., Amling, M., Demay, M. B., Stankovic, K. M. & Rolvien, T., 12.2021, In: J BONE MINER RES. 36, 12, p. 2317-2328 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV

    Vollersen, N., Zhao, W., Rolvien, T., Lange, F., Schmidt, F. N., Sonntag, S., Shmerling, D., von Kroge, S., Stockhausen, K. E., Sharaf, A., Schweizer, M., Karsak, M., Busse, B., Bockamp, E., Semler, O., Amling, M., Oheim, R., Schinke, T. & Yorgan, T. A., 10.11.2021, In: BONE RES. 9, 1, p. 48

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Challenges in the management of tumor-induced osteomalacia (TIO)

    Brandi, M. L., Clunie, G. P. R., Houillier, P., Jan de Beur, S. M., Minisola, S., Oheim, R. & Seefried, L., 11.2021, In: BONE. 152, p. 116064

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  25. Skeletal characterization in a patient with Hajdu-Cheney syndrome undergoing total knee arthroplasty

    von Vopelius, E., Oheim, R., Amling, M., Rolvien, T. & Beil, F. T., 09.2021, In: OSTEOPOROSIS INT. 32, 9, p. 1899-1904 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Bone microarchitecture in patients with autoimmune hepatitis

    Schmidt, C., Stürznickel, J., Strahl, A., Oheim, R., Weiler-Normann, C., Sebode, M., Barvencik, F., Lohse, A. W., Schinke, T., Amling, M., Schramm, C. & Rolvien, T., 07.2021, In: J BONE MINER RES. 36, 7, p. 1316-1325 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Compound heterozygous frameshift mutations in MESD cause a lethal syndrome suggestive of osteogenesis imperfecta type XX

    Stürznickel, J., Jähn-Rickert, K., Zustin, J., Hennig, F., Delsmann, M. M., Schoner, K., Rehder, H., Kreczy, A., Schinke, T., Amling, M., Kornak, U. & Oheim, R., 06.2021, In: J BONE MINER RES. 36, 6, p. 1077-1087 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations

    Butscheidt, S. K., Tsourdi, E., Rolvien, T., Delsmann, A., Stürznickel, J., Barvencik, F., Jakob, F., Hofbauer, L. C., Mundlos, S., Kornak, U., Seefried, L. & Oheim, R., 06.2021, In: BONE. 147, 115911.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Comparison of hamstring and quadriceps tendon autografts in anterior cruciate ligament reconstruction with gait analysis and surface electromyography

    Schagemann, J., Koebrich, T., Wendlandt, R., Schulz, A. P., Gille, J. & Oheim, R., 21.05.2021, In: J ORTHOP TRAUMATOL. 22, 1, 20.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Bilateral Looser zones or pseudofractures in the anteromedial tibia as a component of medial tibial stress syndrome in athletes

    Stürznickel, J., Jandl, N. M., Delsmann, M. M., von Vopelius, E., Barvencik, F., Amling, M., Ueblacker, P., Rolvien, T. & Oheim, R., 05.2021, In: KNEE SURG SPORT TR A. 29, 5, p. 1644-1650 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Response of the ENPP1-deficient skeletal phenotype to oral phosphate supplementation and/or enzyme replacement therapy: Comparative studies in Humans and Mice

    Ferreira, C. R., Kavanagh, D., Oheim, R., Zimmerman, K., Stürznickel, J., Li, X., Stabach, P., Rettig, R. L., Calderone, L., MacKichan, C., Wang, A., Hutchinson, H. A., Nelson, T., Tommassini, S. M., von Kroge, S., Fiedler, I. A. K., Lester, E. R., Moeckel, G. W., Busse, B., Schinke, T., Carpenter, T. O., Levine, M. A., Horwowitz, M. C. & Braddock, D. T., 05.2021, In: J BONE MINER RES. 36, 5, p. 942-955 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Bone healing and reactivation of remodeling under asfotase alfa therapy in adult patients with pediatric-onset hypophosphatasia

    Stürznickel, J., Schmidt, F. N., von Vopelius, E., Delsmann, M. M., Schmidt, C., Jandl, N. M., Oheim, R. & Barvencik, F., 02.2021, In: BONE. 143, p. 115794

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP)

    Stürznickel, J., Rolvien, T., Delsmann, A., Butscheidt, S., Barvencik, F., Mundlos, S., Schinke, T., Kornak, U., Amling, M. & Oheim, R., 02.2021, In: J BONE MINER RES. 36, 2, p. 271-282 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. 2020
  35. Variation in skull bone mineral density of ringed seals (Phoca hispida) from the Gulf of Bothnia and West Greenland between 1829 and 2019

    Schmidt, B., Sonne, C., Nachtsheim, D., Dietz, R., Oheim, R., Rolvien, T., Persson, S., Amling, M. & Siebert, U., 10.2020, In: ENVIRON INT. 143, p. 105968

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Mice carrying a ubiquitous R235W mutation of Wnt1 display a bone-specific phenotype

    Yorgan, T., Rolvien, T., Stürznickel, J., Vollersen, N., Lange, F., Zhao, W., Baranowsky, A., Rosenthal, L., Hermans-Borgmeyer, I., Sharaf, A., Karsak, M., David, J-P., Oheim, R., Amling, M. & Schinke, T., 09.2020, In: J BONE MINER RES. 35, 9, p. 1726-1737 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Whole-Exome Sequencing Identifies Novel Compound Heterozygous ZNF469 Mutations in Two Siblings with Mild Brittle Cornea Syndrome

    Rolvien, T., Kornak, U., Linke, S. J., Amling, M. & Oheim, R., 09.2020, In: CALCIFIED TISSUE INT. 107, 3, p. 294-299 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Adult osteosclerotic metaphyseal dysplasia with progressive osteonecrosis of the jaws and abnormal bone resorption pattern due to a LRRK1 splice site mutation

    Howaldt, A., Hennig, A. F., Rolvien, T., Rössler, U., Stelzer, N., Knaus, A., Böttger, S., Zustin, J., Geißler, S., Oheim, R., Amling, M., Howaldt, H-P. & Kornak, U., 07.2020, In: J BONE MINER RES. 35, 7, p. 1322-1332 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene

    Rolvien, T., Avci, O., von Kroge, S., Koehne, T., Selbert, S., Sonntag, S., Shmerling, D., Kornak, U., Oheim, R., Amling, M., Schinke, T. & Yorgan, T. A., 06.2020, In: BONE REP. 12, p. 100281

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Impaired Bone Microarchitecture in Patients with Hereditary Hemochromatosis and Skeletal Complications

    Jandl, N. M., Rolvien, T., Schmidt, T., Mussawy, H., Nielsen, P., Oheim, R., Amling, M. & Barvencik, F., 05.2020, In: CALCIFIED TISSUE INT. 106, 5, p. 465-475 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Human Heterozygous ENPP1 Deficiency Is Associated With Early Onset Osteoporosis, a Phenotype Recapitulated in a Mouse Model of Enpp1 Deficiency

    Oheim, R., Zimmerman, K., Maulding, N. D., Stürznickel, J., von Kroge, S., Kavanagh, D., Stabach, P. R., Kornak, U., Tommasini, S. M., Horowitz, M. C., Amling, M., Thompson, D., Schinke, T., Busse, B., Carpenter, T. O. & Braddock, D. T., 03.2020, In: J BONE MINER RES. 35, 3, p. 528-539 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Skeletal deterioration in COL2A1-related spondyloepiphyseal dysplasia occurs prior to osteoarthritis

    Rolvien, T., Yorgan, T. A., Kornak, U., Hermans-Borgmeyer, I., Mundlos, S., Schmidt, T., Niemeier, A., Schinke, T., Amling, M. & Oheim, R., 03.2020, In: OSTEOARTHR CARTILAGE. 28, 3, p. 334-343 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. A System to Determine Risk of Osteoporosis in Patients With Autoimmune Hepatitis

    Schmidt, T., Schmidt, C., Strahl, A., Mussawy, H., Rolvien, T., Jandl, N. M., Casar, C., Oheim, R., Schinke, T., Lohse, A. W., Amling, M., Schramm, C. & Barvencik, F., 01.2020, In: CLIN GASTROENTEROL H. 18, 1, p. 226-233.e3

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Mice lacking plastin-3 display a specific defect of cortical bone acquisition

    Yorgan, T., Sari, H., Rolvien, T., Windhorst, S., Failla, A. V., Kornak, U., Oheim, R., Amling, M. & Schinke, T., 01.2020, In: BONE. 130, p. 115062

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. 2019
  46. Intra-articular osteoid osteoma accompanied by extensive bone marrow edema. A clinical and micro-morphological analysis

    Rolvien, T., Krause, M., Zustin, J., Yastrebov, O., Oheim, R., Barvencik, F., Frosch, K-H. & Amling, M., 10.2019, In: J BONE ONCOL. 18, p. 100256

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. High FGF23 levels are associated with impaired trabecular bone microarchitecture in patients with osteoporosis

    Rupp, T., Butscheidt, S., Vettorazzi, E., Oheim, R., Barvencik, F., Amling, M. & Rolvien, T., 08.2019, In: OSTEOPOROSIS INT. 30, 8, p. 1655-1662 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Outcome of Teriparatide Treatment on Fracture Healing Complications and Symptomatic Bone Marrow Edema in Four Adult Patients With Hypophosphatasia

    Schmidt, T., Rolvien, T., Linke, C., Jandl, N. M., Oheim, R., Amling, M. & Barvencik, F., 08.2019, In: JBMR PLUS. 3, 8, p. e10215

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Bone microstructure is significantly altered in CRPS-affected distal tibiae as detected by HR-pQCT: a retrospective cross-sectional study

    Oehler, N., Rolvien, T., Schmidt, T., Butscheidt, S., Oheim, R., Barvencik, F. & Mussawy, H., 07.2019, In: J BONE MINER METAB. 37, 4, p. 741-748 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Th17 cell frequency is associated with low bone mass in primary sclerosing cholangitis

    Schmidt, T., Schwinge, D., Rolvien, T., Jeschke, A., Schmidt, C., Neven, M., Butscheidt, S., Kriz, M., Kunzmann, L., Mussawy, H., Hubert, J., Hawellek, T., Rüther, W., Oheim, R., Barvencik, F., Lohse, A. W., Schramm, C., Schinke, T. & Amling, M., 05.2019, In: J HEPATOL. 70, 5, p. 941-953 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. A novel FAM20C mutation causing hypophosphatemic osteomalacia with osteosclerosis (mild Raine syndrome) in an elderly man with spontaneous osteonecrosis of the knee

    Rolvien, T., Kornak, U., Schinke, T., Amling, M. & Oheim, R., 03.2019, In: OSTEOPOROSIS INT. 30, 3, p. 685-689 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. 2018
  53. Ultra-high matrix mineralization of sperm whale auditory ossicles facilitates high sound pressure and high-frequency underwater hearing

    Schmidt, F. N., Delsmann, M. M., Mletzko, K., Yorgan, T. A., Hahn, M., Siebert, U., Busse, B., Oheim, R., Amling, M. & Rolvien, T., 19.12.2018, In: P ROY SOC B-BIOL SCI. 285, 1893, p. 20181820 1 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand

    Luther, J., Yorgan, T. A., Rolvien, T., Ulsamer, L., Koehne, T., Liao, N., Keller, D., Vollersen, N., Teufel, S., Neven, M., Peters, S., Schweizer, M., Trumpp, A., Rosigkeit, S., Bockamp, E., Mundlos, S., Kornak, U., Oheim, R., Amling, M., Schinke, T. & David, J-P., 07.11.2018, In: SCI TRANSL MED. 10, 466, p. eaau7137

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Comparison of Bone Microarchitecture Between Adult Osteogenesis Imperfecta and Early-Onset Osteoporosis

    Rolvien, T., Stürznickel, J., Schmidt, F. N., Butscheidt, S., Schmidt, T., Busse, B., Mundlos, S., Schinke, T., Kornak, U., Amling, M. & Oheim, R., 11.2018, In: CALCIFIED TISSUE INT. 103, 5, p. 512-521 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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