Prof.Dr. ID: 39068
Rainer Böger
Publications
- 2020
Dual role of the L-arginine-ADMA-NO pathway in systemic hypoxic vasodilation and pulmonary hypoxic vasoconstriction
Böger, R. & Hannemann, J., 22.04.2020, In: PULM CIRC. 10, 2, p. 2045894020918850Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Metabolism of asymmetric dimethylarginine in hypoxia: from bench to bedside
Hannemann, J., Zummack, J., Hillig, J. & Böger, R., 22.04.2020, In: PULM CIRC. 10, 2, p. 2045894020918846Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pre-Analytical and Clinical Validation of a Dried Blood Spot Assay for Asymmetric Dimethylarginine and L-Arginine
Hannemann, J., Roskam, T. I., Eilermann, I., Siques, P., Brito, J. & Böger, R., 09.04.2020, In: J CLIN MED. 9, 4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Determinants of Serum- and Plasma Sphingosine-1-Phosphate Concentrations in a Healthy Study Group
Daum, G., Winkler, M., Moritz, E., Müller, T., Geffken, M., von Lucadou, M., Haddad, M., Peine, S., Böger, R. H., Larena-Avellaneda, A., Debus, E. S., Gräler, M. & Schwedhelm, E., 01.2020, In: TH Open. 4, 1, p. e12-e19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low homoarginine/SDMA ratio is associated with poor short- and long-term outcome after stroke in two prospective studies
Choe, C-U., Lezius, S., Cordts, K., Gerloff, C., Böger, R. H., Schwedhelm, E. & Grant, P. J., 01.2020, In: NEUROL SCI. 41, 1, p. 149-153 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Muscle phenotype of AGAT- and GAMT-deficient mice after simvastatin exposure
Sasani, A., Hornig, S., Grzybowski, R., Cordts, K., Hanff, E., Tsikas, D., Böger, R., Gerloff, C., Isbrandt, D., Neu, A., Schwedhelm, E. & Choe, C-U., 01.2020, In: AMINO ACIDS. 52, 1, p. 73-85 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Upregulation of DDAH2 Limits Pulmonary Hypertension and Right Ventricular Hypertrophy During Chronic Hypoxia in Ddah1 Knockout Mice
Hannemann, J., Glatzel, A., Hillig, J., Zummack, J., Schumacher, U., Lüneburg, N., Harbaum, L. & Böger, R., 2020, In: FRONT PHYSIOL. 11, p. 597559Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Dronedarone induces regression of coronary artery remodeling related to better global antioxidant status
Quintana-Villamandos, B., Pazó-Sayós, L., Arribas, S. M., Rodríguez-Rodríguez, P., Böger, R. H., Lüneburg, N., Delgado-Baeza, E. & González, M. C., 10.2019, In: HYPERTENS RES. 42, 10, p. 1485-1494 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension
Hennigs, J. K., Lüneburg, N., Stage, A., Schmitz, M., Körbelin, J., Harbaum, L., Matuszcak, C., Mienert, J., Bokemeyer, C., Böger, R. H., Kiefmann, R. & Klose, H., 09.2019, In: PURINERG SIGNAL. 15, 3, p. 299-311 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy
Cordts, K., Seelig, D., Lund, N., Carrier, L., Böger, R. H., Avanesov, M., Tahir, E., Schwedhelm, E. & Patten, M., 13.07.2019, In: BIOMOLECULES. 9, 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effect of ranolazine on plasma arginine derivatives and urinary isoprostane 8-iso-PGF2α in patients with myocardial infarction in the randomized RIMINI-Trial
Schwemer, T. F., Deutscher, N., Diermann, N., Böger, R., Schwedhelm, E., Blankenberg, S. & Friedrich, F. W., 05.04.2019, In: SCI REP-UK. 9, 1, p. 5708Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA(2)DS(2)-VASc score in three cross-sectional studies
Cordts, K., Grzybowski, R., Lezius, S., Lüneburg, N., Atzler, D., Neu, A., Hornig, S., Böger, R. H., Gerloff, C., Magnus, T., Thomalla, G., Schwedhelm, E., Grant, P. J. & Choe, C-U., 15.02.2019, In: J NEUROL SCI. 397, p. 156-161 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude
Siques, P., Brito, J., Schwedhelm, E., Pena, E., León-Velarde, F., De La Cruz, J. J., Böger, R. H. & Hannemann, J., 2019, In: FRONT PHYSIOL. 10, p. 651Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The protective effect of dronedarone on the structure and mechanical properties of the aorta in hypertensive rats by decreasing the concentration of symmetric dimethylarginine (SDMA)
Quintana-Villamandos, B., González, M. D. C., Delgado-Martos, M. J., Gutiérrez-Arzapalo, P. Y., Böger, R. H., Lüneburg, N., Muñoz, D. & Delgado-Baeza, E., 2019, In: PLOS ONE. 14, 5, e0216820.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival
Winkler, M. S., Nierhaus, A., Rösler, G., Lezius, S., Harlandt, O., Schwedhelm, E., Böger, R. & Kluge, S., 19.09.2018, In: CRIT CARE. 22, 1, p. 216Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relationship between exercise intervention and NO pathway in patients with heart failure with preserved ejection fraction
Baldassarri, F., Schwedhelm, E., Atzler, D., Böger, R. H., Cordts, K., Haller, B., Pressler, A., Müller, S., Suchy, C., Wachter, R., Düngen, H-D., Hasenfuss, G., Pieske, B., Halle, M., Edelmann, F. & Duvinage, A., 09.2018, In: BIOMARKERS. 23, 6, p. 540-550 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study
Niekamp, C., Atzler, D., Ojeda, F. M., Sinning, C. R., Lackner, K. J., Böger, R. H., Munzel, T., Beutel, M. E., Schmidtmann, I., Pfeiffer, N., Leuschner, A., Blankenberg, S., Wild, P. S., Zeller, T., Schwedhelm, E. & Schnabel, R. B., 30.08.2018, In: BIOMOLECULES. 8, 3, p. E86Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage
Appel, D., Seeberger, M., Schwedhelm, E., Czorlich, P., Goetz, A. E., Böger, R. H. & Hannemann, J., 08.2018, In: NEUROCRIT CARE. 29, 1, p. 84-93 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low-Circulating Homoarginine is Associated with Dilatation and Decreased Function of the Left Ventricle in the General Population
Bahls, M., Atzler, D., Markus, M. R. P., Friedrich, N., Böger, R. H., Völzke, H., Felix, S. B., Schwedhelm, E. & Dörr, M., 30.07.2018, In: BIOMOLECULES. 8, 3, p. e63Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks
Schönhoff, M., Weineck, G., Hoppe, J., Hornig, S., Cordts, K., Atzler, D., Gerloff, C., Böger, R., Neu, A., Schwedhelm, E. & Choe, C-U., 04.2018, In: J CLIN NEUROSCI. 50, p. 237-241 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analgetika
Böger, R. & Schmidt, G., 2018, Arzneiverordnungs-Report 2018. Schwabe, U., Paffrath, D., Ludwig, W-D. & Klauber, J. (eds.). 1 ed. Springer-Verlag Berlin, Heidelberg, p. 289-301 12 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Antirheumatika und Antiphlogistika
Böger, R. & Schmidt, G., 2018, Arzneiverordnungs-Report 2018. Schwabe, U., Paffrath, D., Ludwig, W-D. & Klauber, J. (eds.). 1 ed. Springer-Verlag Berlin, Heidelberg, p. 423-434 12 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Development and implementation of a cell-based assay to discover agonists of the nuclear receptor REV-ERBα
Hering, Y., Berthier, A., Duez, H., Lefebvre, P., Deprez, B., Gribbon, P., Wolf, M., Reinshagen, J., Halley, F., Hannemann, J., Böger, R., Staels, B. & Gul, S., 2018, In: Journal of biological methods. 5, 3, p. e94Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-Term Intermittent Work at High Altitude: Right Heart Functional and Morphological Status and Associated Cardiometabolic Factors
Brito, J., Siques, P., López, R., Romero, R., León-Velarde, F., Flores, K., Lüneburg, N., Hannemann, J. & Böger, R. H., 2018, In: FRONT PHYSIOL. 9, p. 248Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Plasma Nitrate and Incidence of Cardiovascular Disease and All-Cause Mortality in the Community: The Framingham Offspring Study
Maas, R., Xanthakis, V., Göen, T., Müller, J., Schwedhelm, E., Böger, R. H. & Vasan, R. S., 18.11.2017, In: J AM HEART ASSOC. 6, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Asymmetric dimethylarginine and symmetric dimethylarginine prospectively relates to carotid wall thickening in black men - the SABPA study
Mels, C. M. C., Schutte, A. E., Huisman, H. W., Smith, W., Kruger, R., Van Rooyen, J. M., Schwedhelm, E., Atzler, D., Böger, R. H., Malan, N. T. & Malan, L., 11.2017, In: AMINO ACIDS. 49, 11, p. 1843-1853Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults
Lüneburg, N., Siques, P., Brito, J., De La Cruz, J. J., León-Velarde, F., Hannemann, J., Ibanez, C. & Böger, R. H., 09.2017, In: HIGH ALT MED BIOL. 18, 3, p. 226-233 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction
Xu, X., Zhang, P., Kwak, D., Fassett, J., Yue, W., Atzler, D., Hu, X., Liu, X., Wang, H., Lu, Z., Guo, H., Schwedhelm, E., Böger, R. H., Chen, P. & Chen, Y., 17.08.2017, In: BASIC RES CARDIOL. 112, 5, p. 55Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Markers of nitric oxide are associated with sepsis severity: an observational study
Winkler, M. S., Kluge, S., Holzmann, M., Moritz, E., Robbe, L., Bauer, A., Zahrte, C., Priefler, M., Schwedhelm, E., Böger, R. H., Goetz, A. E., Nierhaus, A. & Zoellner, C., 15.07.2017, In: CRIT CARE. 21, 1, p. 189Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Data on subgroup specific baseline characteristics and serum sphingosine-1-phosphate concentrations in the Study of Health in Pomerania
Moritz, E., Wegner, D., Groß, S., Bahls, M., Dörr, M., Felix, S. B., Ittermann, T., Oswald, S., Nauck, M., Friedrich, N., Böger, R. H., Daum, G., Schwedhelm, E. & Rauch, B. H., 06.2017, In: DATA BRIEF. 12, p. 46-50 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease
Zewinger, S., Kleber, M. E., Rohrer, L., Lehmann, M., Triem, S., Jennings, R. T., Petrakis, I., Dressel, A., Lepper, P. M., Scharnagl, H., Ritsch, A., Thorand, B., Heier, M., Meisinger, C., de Las Heras Gala, T., Koenig, W., Wagenpfeil, S., Schwedhelm, E., Böger, R. H., Laufs, U., Eckardstein, A. V., Landmesser, U., Lüscher, T. F., Fliser, D., März, W., Meinitzer, A. & Speer, T., 21.05.2017, In: EUR HEART J. 38, 20, p. 1597-1607 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania
Moritz, E., Wegner, D., Groß, S., Bahls, M., Dörr, M., Felix, S. B., Ittermann, T., Oswald, S., Nauck, M., Friedrich, N., Böger, R. H., Daum, G., Schwedhelm, E. & Rauch, B. H., 05.2017, In: CLIN CHIM ACTA. 468, p. 25-31 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Higher serum asymmetric dimethylarginine is related to higher risk of heart failure in the EPIC-Potsdam study
Wirth, J., Atzler, D., di Giuseppe, R., Cordts, K., Menzel, J., Böger, R. H., Boeing, H., Weikert, C. & Schwedhelm, E., 01.2017, In: AMINO ACIDS. 49, 1, p. 173-182Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Akrinor(TM), a Cafedrine/ Theodrenaline Mixture (20:1), Increases Force of Contraction of Human Atrial Myocardium But Does Not Constrict Internal Mammary Artery In Vitro
Kloth, B., Pecha, S., Moritz, E., Schneeberger, Y., Söhren, K-D., Schwedhelm, E., Reichenspurner, H., Eschenhagen, T., Böger, R. H., Christ, T. & Stehr, S. N., 2017, In: FRONT PHARMACOL. 8, p. 272Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Oral supplementation with L-homoarginine in young volunteers
Atzler, D., Schönhoff, M., Cordts, K., Ortland, I., Hoppe, J., Hummel, F. C., Gerloff, C., Jaehde, U., Jagodzinski, A., Böger, R. H., Choe, C-U. & Schwedhelm, E., 12.2016, In: BRIT J CLIN PHARMACO. 82, 6, p. 1477-1485Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels
Zhang, W., Jernerén, F., Lehne, B. C., Chen, M-H., Luben, R. N., Johnston, C., Elshorbagy, A., Eppinga, R. N., Scott, W. R., Adeyeye, E., Scott, J., Böger, R. H., Khaw, K-T., van der Harst, P., Wareham, N. J., Vasan, R. S., Chambers, J. C., Refsum, H. & Kooner, J. S., 30.11.2016, In: THROMB HAEMOSTASIS. 116, 6, p. 1041-1049 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Short-term esmolol attenuates remodeling of the thoracic aorta in hypertensive rats by decreasing concentrations of ADMA down-regulated by oxidative stress
Quintana-Villamandos, B., González, M. C., Delgado-Martos, M. J., Condezo-Hoyos, L., Böger, R. H., Lüneburg, N., Pazó-Sayós, L., Gutiérrez-Arzapalo, P. Y. & Delgado-Baeza, E., 15.11.2016, In: EUR J PHARMACOL. 791, p. 502-509 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension
Harbaum, L., Renk, E., Yousef, S., Glatzel, A., Lüneburg, N., Hennigs, J. K., Oqueka, T., Baumann, H. J., Atanackovic, D., Grünig, E., Böger, R. H., Bokemeyer, C. & Klose, H., 11.11.2016, In: BMC PULM MED. 16, 1, p. 145Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Early regression of coronary artery remodeling with esmolol and DDAH/ADMA pathway in hypertensive rats
Quintana-Villamandos, B., Arnalich-Montiel, A., Arribas, S., Lüneburg, N., Böger, R. H., Delgado-Martos, M. J., Fernández-Criado, C., Delgado-Baeza, E. & González, M. C., 10.2016, In: HYPERTENS RES. 39, 10, p. 692-700 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homoarginine predicts mortality in treatment-naive patients with pulmonary arterial hypertension
Atzler, D., Cracowski, J-L., Cordts, K., Böger, R. H., Humbert, M. & Schwedhelm, E., 15.08.2016, In: INT J CARDIOL. 217, p. 12-5 4 p.Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Reference intervals of plasma homoarginine from the German Gutenberg Health Study
Atzler, D., Appelbaum, S., Cordts, K., Ojeda, F. M., Wild, P. S., Münzel, T., Blankenberg, S., Böger, R. H., Blettner, M., Beutel, M. E., Pfeiffer, N., Zeller, T., Lackner, K. J. & Schwedhelm, E., 01.07.2016, In: CLIN CHEM LAB MED. 54, 7, p. 1231-7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Asymmetric dimethylarginine, related arginine derivatives, and incident atrial fibrillation
Schnabel, R. B., Maas, R., Wang, N., Yin, X., Larson, M. G., Levy, D., Ellinor, P. T., Lubitz, S. A., McManus, D. D., Magnani, J. W., Atzler, D., Böger, R. H., Schwedhelm, E., Vasan, R. S. & Benjamin, E. J., 06.2016, In: AM HEART J. 176, p. 100-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain
Atzler, D., Baum, C., Ojeda, F., Keller, T., Cordts, K., Schnabel, R. B., Choe, C., Lackner, K. J., Münzel, T., Böger, R. H., Blankenberg, S., Schwedhelm, E. & Zeller, T., 13.04.2016, In: J AM HEART ASSOC. 5, 4, p. e002565Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white Population: the SABPA study
Mels, C. M. C., Loots, I., Schwedhelm, E., Atzler, D., Böger, R. H. & Schutte, A. E., 01.03.2016, In: AMINO ACIDS. 48, 3, p. 801-10Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
L-Arginine Derivatives Are Associated with the Hyperthyroid State in the General Population
Ittermann, T., Bahls, M., Atzler, D., Friedrich, N., Schwedhelm, E., Böger, R. H., Felix, S. B., Völzke, H. & Dörr, M., 02.2016, In: THYROID. 26, 2, p. 212-8 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The relationship of nitric oxide synthesis capacity, oxidative stress, and albumin-to-creatinine ratio in black and white men: the SABPA study
Mels, C. M. C., Huisman, H. W., Smith, W., Schutte, R., Schwedhelm, E., Atzler, D., Böger, R. H., Ware, L. J. & Schutte, A. E., 02.2016, In: AGE (DORDR). 38, 1, p. 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ADMA, subclinical changes and atrial fibrillation in the general population
Ramuschkat, M., Appelbaum, S., Atzler, D., Zeller, T., Bauer, C., Ojeda, F. M., Sinning, C. R., Hoffmann, B., Lackner, K. J., Böger, R. H., Wild, P. S., Münzel, T., Blankenberg, S., Schwedhelm, E., Schnabel, R. B. & Gutenberg Health Study investigators, 15.01.2016, In: INT J CARDIOL. 203, p. 640-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ADMA and arginine derivatives in relation to non-invasive vascular function in the general population
Baum, C., Johannsen, S. S., Zeller, T., Atzler, D., Ojeda, F. M., Wild, P. S., Sinning, C. R., Lackner, K. J., Gori, T., Schwedhelm, E., Böger, R. H., Blankenberg, S., Münzel, T., Schnabel, R. B. & Gutenberg Health Study investigators, 01.2016, In: ATHEROSCLEROSIS. 244, p. 149-56 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?
Lüneburg, N., Siques, P., Brito, J., Arriaza, K., Pena, E., Klose, H., Leon-Velarde, F. & Böger, R. H., 2016, In: Pulmonary medicine. 2016, p. 6578578Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis
Menghini, R., Casagrande, V., Cardellini, M., Ballanti, M., Davato, F., Cardolini, I., Stoehr, R., Fabrizi, M., Morelli, M., Anemona, L., Bernges, I., Schwedhelm, E., Ippoliti, A., Mauriello, A., Böger, R. H. & Federici, M., 09.2015, In: ATHEROSCLEROSIS. 242, 1, p. 230-5 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review