Dr.rer.nat. ID: 67065
Kerstin Cornils
Publications
- 2024
Glycan Structures in Osteosarcoma as Targets for Lectin-Based Chimeric Antigen Receptor Immunotherapy
Prasse, N., Wessolowski, C., Müller, I., Cornils, K. & Franke, A-K., 14.05.2024, In: INT J MOL SCI. 25, 10, 5344.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation
Alhaj Hussen, K., Chabaane, E., Nelson, E., Lekiashvili, S., Diop, S., Keita, S., Evrard, B., Lardenois, A., Delord, M., Verhoeyen, E., Cornils, K., Kasraian, Z., Macintyre, E. A., Cumano, A., Garrick, D., Goodhardt, M., Andrieu, G. P., Asnafi, V., Chalmel, F. & Canque, B., 20.10.2023, In: ISCIENCE. 26, 10, 107890.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Glyco-binding domain chimeric antigen receptors as a new option for cancer immunotherapy
Franke, A-K., Wessolowski, C., Thaden, V., Müller, I. & Cornils, K., 08.2023, In: GENE THER. 30, 7-8, p. 603-611 9 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity
Schütze, K., Groß, M., Cornils, K., Wustrau, K., Schneppenheim, S., Lenhartz, H., Korenke, G-C., Janka, G., Ledig, S., Müller, I., Ehl, S. & Lehmberg, K., 25.04.2023, In: BLOOD ADV. 7, 8, p. 1531-1535 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Reduced adhesion of aged intestinal stem cells contributes to an accelerated clonal drift
Hageb, A., Thalheim, T., Nattamai, K. J., Möhrle, B., Saçma, M., Sakk, V., Thielecke, L., Kerstin, C., Grandy, C., Port, F., Gottschalk, K-E., Mallm, J-P., Glauche, I., Galle, J., Mulaw, M. A. & Geiger, H., 08.2022, In: LIFE SCI ALLIANCE. 5, 8, e202201408.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age
Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
genBaRcode - a comprehensive R package for genetic barcode analysis
Thielecke, L., Cornils, K. & Glauche, I., 01.04.2020, In: BIOINFORMATICS. 36, 7, p. 2189-2194 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia
Velthaus, A., Cornils, K., Hennigs, J. K., Grüb, S., Stamm, H., Wicklein, D., Bokemeyer, C., Heuser, M., Windhorst, S., Fiedler, W. & Wellbrock, J., 26.10.2019, In: CANCERS. 11, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge
Shemer, A., Grozovski, J., Tay, T. L., Tao, J., Volaski, A., Süß, P., Ardura-Fabregat, A., Gross-Vered, M., Kim, J-S., David, E., Chappell-Maor, L., Thielecke, L., Glass, C. K., Cornils, K., Prinz, M. & Jung, S., 06.12.2018, In: NAT COMMUN. 9, 1, p. 5206Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A track of the clones: new developments in cellular barcoding
Lyne, A-M., Kent, D. G., Laurenti, E., Cornils, K., Glauche, I. & Perié, L., 12.2018, In: EXP HEMATOL. 68, p. 15-20 6 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma
Roh, V., Abramowski, P., Hiou-Feige, A., Cornils, K., Rivals, J-P., Zougman, A., Aranyossy, T., Thielecke, L., Truan, Z., Mermod, M., Monnier, Y., Prassolov, V., Glauche, I., Nowrouzi, A., Abdollahi, A., Fehse, B., Simon, C. & Tolstonog, G. V., 20.11.2018, In: CELL REP. 25, 8, p. 2208-2222.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal Proteome and Secretome Analysis Identifies Missorted Enzymes and Their Nondegraded Substrates in Mucolipidosis III Mouse Cells
Di Lorenzo, G., Velho, R. V., Winter, D., Thelen, M., Ahmadi, S., Schweizer, M., De Pace, R., Cornils, K., Yorgan, T. A., Grüb, S., Hermans-Borgmeyer, I., Schinke, T., Müller-Loennies, S., Braulke, T. & Pohl, S., 08.2018, In: MOL CELL PROTEOMICS. 17, 8, p. 1612-1626 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High bone turnover in mice carrying a pathogenic Notch2-mutation causing Hajdu-Cheney syndrome
Vollersen, N., Hermans-Borgmeyer, I., Cornils, K., Fehse, B., Rolvien, T., Triviai, I., Jeschke, A., Oheim, R., Amling, M., Schinke, T. & Yorgan, T. A., 01.2018, In: J BONE MINER RES. 33, 1, p. 70-83 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model
Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In: ONCOTARGET. 8, 70, p. 115582-115595 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent
Lévy, C., Amirache, F., Girard-Gagnepain, A., Frecha, C., Roman-Rodríguez, F. J., Bernadin, O., Costa, C., Nègre, D., Gutierrez-Guerrero, A., Vranckx, L. S., Clerc, I., Taylor, N., Thielecke, L., Cornils, K., Bueren, J. A., Rio, P., Gijsbers, R., Cosset, F-L. & Verhoeyen, E., 24.10.2017, In: Blood Adv. 1, 23, p. 2088-2104 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic barcodes facilitate competitive clonal analyses in vivo
Aranyossy, T., Thielecke, L., Glauche, I., Fehse, B. & Cornils, K., 10.2017, In: HUM GENE THER. 28, 10, p. 926-937Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enzymatic characterization of novel arylsulfatase A variants using human arylsulfatase A-deficient immortalized mesenchymal stromal cells
Böhringer, J., Santer, R., Schumacher, N., Gieseke, F., Cornils, K., Pechan, M., Kustermann-Kuhn, B., Handgretinger, R., Schöls, L., Harzer, K., Krägeloh-Mann, I. & Müller, I., 31.07.2017, In: HUM MUTAT. 38, 11, p. 1511-1520Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion
Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In: MOL CANCER. 16, 1, p. 120Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limitations and challenges of genetic barcode quantification
Thielecke, L., Aranyossy, T., Dahl, A., Tiwari, R., Roeder, I., Geiger, H., Fehse, B., Glauche, I. & Cornils, K., 03.03.2017, In: SCI REP-UK. 7, p. 43249Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles
Fischer, S., Cornils, K., Speiseder, T., Badbaran, A., Reimer, R., Indenbirken, D., Grundhoff, A., Brunswig-Spickenheier, B., Alawi, M. & Lange, C., 30.09.2016, In: PLOS ONE. 11, 9, p. e0163665Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology
Selich, A., Daudert, J., Hass, R., Philipp, F., von Kaisenberg, C., Paul, G., Cornils, K., Fehse, B., Rittinghausen, S., Schambach, A. & Rothe, M., 05.2016, In: STEM CELL TRANSL MED. 5, 5, p. 591-601 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Investigation of the Mesenchymal Stem Cell Compartment by Means of a Lentiviral Barcode Library
Bigildeev, A. E., Cornils, K., Aranyossy, T., Sats, N. V., Petinati, N. A., Shipounova, I. N., Surin, V. L., Pshenichnikova, O. S., Riecken, K., Fehse, B. & Drize, N. I., 04.2016, In: BIOCHEMISTRY-MOSCOW+. 81, 4, p. 373-81 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I
Kühn, S. C., Koehne, T., Cornils, K., Markmann, S., Riedel, C., Pestka, J. M., Schweizer, M., Baldauf, C., Yorgan, T. A., Krause, M., Keller, J., Neven, M., Breyer, S., Stücker, R., Muschol, N., Busse, B., Braulke, T., Fehse, B., Amling, M. & Schinke, T., 15.12.2015, In: HUM MOL GENET. 24, 24, p. 7075-7086Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lrp1/LDL receptor play critical roles in mannose 6-phosphate-independent lysosomal enzyme targeting
Markmann, S., Thelen, M., Cornils, K., Schweizer, M., Brocke-Ahmadinejad, N., Willnow, T., Heeren, J., Gieselmann, V., Braulke, T. & Kollmann, K., 18.03.2015, In: TRAFFIC.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetische Manipulation: klinische Anwendung.
Fehse, B. & Cornils, K., 2015, Hämatopoetische Stammzellen: Grundlagen und klinische Einsatzgebiete. Herr, W., Theobald, M., Ehninger, G., Einsele, H. & Meyer, R. G. (eds.). 1 ed. Köln: Deutscher Ärzte-Verlag, p. 21-24 4 p. 6Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research
Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis
Heim, D., Cornils, K., Schulze, K., Fehse, B., Lohse, A. W., Brümmendorf, T. H. & Wege, H., 2015, In: ONCOGENE. 34, 3, p. 385-393Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells
Kötter, A., Cornils, K., Borgmann, K., Dahm-Daphi, J., Petersen, C., Dikomey, E. & Mansour Khalfallah, W. Y., 01.12.2014, In: MOL ONCOL. 8, 8, p. 1616-25 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiplexing clonality: combining RGB marking and genetic barcoding
Cornils, K., Thielecke, L., Hüser, S., Forgber, M., Thomaschewski, M., Kleist, N., Hussein, K., Riecken, K., Volz, T., Gerdes, S., Glauche, I., Dahl, A., Dandri, M., Roeder, I. & Fehse, B., 01.04.2014, In: NUCLEIC ACIDS RES. 42, 7, p. e56Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or a γ-retroviral LTR vector
Cornils, K., Bartholomae, C. C., Thielecke, L., Lange, C., Arens, A., Glauche, I., Mock, U., Riecken, K., Gerdes, S., von Kalle, C., Schmidt, M., Roeder, I. & Fehse, B., 01.01.2013, In: EXP HEMATOL. 41, 1, p. 28-38.e3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
RGB marking : Vielfarbige Zellmarkierung zur klonalen Analyse
Riecken, K., Thomaschewski, M., Warlich, M., Cornils, K., Benten, D. & Fehse, B., 2012, In: Laborwelt. 13, 1, p. 7-9 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radiation rescue: mesenchymal stromal cells protect from lethal irradiation.
Lange, C., Brunswig-Spickenheier, B., Capallo-Obermann, H., Eggert, K., Gehling, U., Rudolph, C., Schlegelberger, B., Cornils, K., Zustin, J., Spiess, A-N. & Zander, A. R., 2011, In: PLOS ONE. 6, 1, p. 14486 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.
Newrzela, S., Cornils, K., Heinrich, T., Schläger, J., Yi, J-H., Lysenko, O., Kimpel, J., Fehse, B. & Dorothee, V. L., 2011, In: MOL MED. 17, 11-12, p. 1223-1232 11-12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking facilitates multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.
Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Resistance of mature T cells to oncogene transformation.
Newrzela, S., Cornils, K., Li, Z., Baum, C., Brugman, M. H., Hartmann, M., Meyer, J., Hartmann, S., Hansmann, M-L., Fehse, B. & von Laer, D., 2008, In: BLOOD. 112, 6, p. 2278-2286 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b.
Fliegert, R., Glassmeier, G., Schmid, F., Cornils, K., Genisyuerek, S., Harneit, A., Schwarz, J. R. & Guse, A. H., 2007, In: FEBS J. 274, 3, p. 704-713 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
Kustikova, O. S., Geiger, H., Li, Z., Brugman, M. H., Chambers, S. M., Shaw, C. A., Pike-Overzet, K., de Ridder, D., Staal, F. J. T., von Keudell, G., Cornils, K., Nattamai, K. J., Modlich, U., Wagemaker, G., Goodell, M. A., Fehse, B. & Baum, C., 2007, In: BLOOD. 109, 5, p. 1897-1907 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Dynamic expression of LIM cofactors in the developing mouse neural tube.
Ostendorff, H. P., Tursun, B., Cornils, K., Schlüter, A., Drung, A., Güngör, C. & Bach, I., 2006, In: DEV DYNAM. 235, 3, p. 786-791 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review