Prof. Dr. ID: 2375364
Kai Rothkamm
Publications
- 2013
Deoxyribonucleic acid damage-associated biomarkers of ionising radiation: current status and future relevance for radiology and radiotherapy
Manning, G. & Rothkamm, K., 07.2013, In: BRIT J RADIOL. 86, 1027, p. 20130173Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Homologous recombination mediates cellular resistance and fraction size sensitivity to radiation therapy
Somaiah, N., Yarnold, J., Lagerqvist, A., Rothkamm, K. & Helleday, T., 07.2013, In: RADIOTHER ONCOL. 108, 1, p. 155-61 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The shape of the radiation dose response for DNA double-strand break induction and repair
Barnard, S., Bouffler, S. & Rothkamm, K., 22.03.2013, In: Genome integrity. 4, 1, p. 1Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome
Gribble, S. M., Wiseman, F. K., Clayton, S., Prigmore, E., Langley, E., Yang, F., Maguire, S., Fu, B., Rajan, D., Sheppard, O., Scott, C., Hauser, H., Stephens, P. J., Stebbings, L. A., Ng, B. L., Fitzgerald, T., Quail, M. A., Banerjee, R., Rothkamm, K., Tybulewicz, V. L. J., Fisher, E. M. C. & Carter, N. P., 2013, In: PLOS ONE. 8, 4, p. e60482Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy
Somaiah, N., Yarnold, J., Daley, F., Pearson, A., Gothard, L., Rothkamm, K. & Helleday, T., 01.10.2012, In: CLIN CANCER RES. 18, 19, p. 5479-88 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ionizing radiation biomarkers for potential use in epidemiological studies
Pernot, E., Hall, J., Baatout, S., Benotmane, M. A., Blanchardon, E., Bouffler, S., El Saghire, H., Gomolka, M., Guertler, A., Harms-Ringdahl, M., Jeggo, P., Kreuzer, M., Laurier, D., Lindholm, C., Mkacher, R., Quintens, R., Rothkamm, K., Sabatier, L., Tapio, S., de Vathaire, F. & Cardis, E., 09.06.2012, In: MUTAT RES-FUND MOL M. 751, 2, p. 258-86 29 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
In situ biological dose mapping estimates the radiation burden delivered to 'spared' tissue between synchrotron X-ray microbeam radiotherapy tracks
Rothkamm, K., Crosbie, J. C., Daley, F., Bourne, S., Barber, P. R., Vojnovic, B., Cann, L. & Rogers, P. A. W., 2012, In: PLOS ONE. 7, 1, p. e29853Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Review of retrospective dosimetry techniques for external ionising radiation exposures
Ainsbury, E. A., Bakhanova, E., Barquinero, J. F., Brai, M., Chumak, V., Correcher, V., Darroudi, F., Fattibene, P., Gruel, G., Guclu, I., Horn, S., Jaworska, A., Kulka, U., Lindholm, C., Lloyd, D., Longo, A., Marrale, M., Monteiro Gil, O., Oestreicher, U., Pajic, J., Rakic, B., Romm, H., Trompier, F., Veronese, I., Voisin, P., Vral, A., Whitehouse, C. A., Wieser, A., Woda, C., Wojcik, A. & Rothkamm, K., 11.2011, In: RADIAT PROT DOSIM. 147, 4, p. 573-92 20 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy
Chua, M. L. K., Somaiah, N., A'Hern, R., Davies, S., Gothard, L., Yarnold, J. & Rothkamm, K., 06.2011, In: RADIOTHER ONCOL. 99, 3, p. 362-6 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin
Chua, M. L. K., Somaiah, N., Bourne, S., Daley, F., A'hern, R., Nuta, O., Davies, S., Herskind, C., Pearson, A., Warrington, J., Helyer, S., Owen, R., Yarnold, J. & Rothkamm, K., 05.2011, In: RADIOTHER ONCOL. 99, 2, p. 225-30 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Triage, monitoring and dose assessment for people exposed to ionising radiation following a malevolent act
Etherington, G., Rothkamm, K., Shutt, A. L. & Youngman, M. J., 03.2011, In: RADIAT PROT DOSIM. 144, 1-4, p. 534-9 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells
Bauerschmidt, C., Woodcock, M., Stevens, D. L., Hill, M. A., Rothkamm, K. & Helleday, T., 01.02.2011, In: EXP CELL RES. 317, 3, p. 330-7 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gamma-H2AX-based dose estimation for whole and partial body radiation exposure
Horn, S., Barnard, S. & Rothkamm, K., 2011, In: PLOS ONE. 6, 9, p. e25113Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ionizing radiation-induced DNA strand breaks and γ-H2AXγ-H2AX foci in cells exposed to nitric oxide
Rothkamm, K. & Burdak-Rothkamm, S., 2011, In: Methods Mol Biol. 704, p. 17-25 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Limitations associated with analysis of cytogenetic data for biological dosimetry
Vinnikov, V. A., Ainsbury, E. A., Maznyk, N. A., Lloyd, D. C. & Rothkamm, K., 10.2010, In: RADIAT RES. 174, 4, p. 403-14 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues
Crosbie, J. C., Anderson, R. L., Rothkamm, K., Restall, C. M., Cann, L., Ruwanpura, S., Meachem, S., Yagi, N., Svalbe, I., Lewis, R. A., Williams, B. R. G. & Rogers, P. A. W., 01.07.2010, In: INT J RADIAT ONCOL. 77, 3, p. 886-94 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
Bauerschmidt, C., Arrichiello, C., Burdak-Rothkamm, S., Woodcock, M., Hill, M. A., Stevens, D. L. & Rothkamm, K., 01.2010, In: NUCLEIC ACIDS RES. 38, 2, p. 477-87 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Interlaboratory variation in scoring dicentric chromosomes in a case of partial-body x-ray exposure: implications for biodosimetry networking and cytogenetic "triage mode" scoring
Ainsbury, E. A., Livingston, G. K., Abbott, M. G., Moquet, J. E., Hone, P. A., Jenkins, M. S., Christensen, D. M., Lloyd, D. C. & Rothkamm, K., 12.2009, In: RADIAT RES. 172, 6, p. 746-52 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA and chromosomal damage in response to intermittent extremely low-frequency magnetic fields
Burdak-Rothkamm, S., Rothkamm, K., Folkard, M., Patel, G., Hone, P., Lloyd, D., Ainsbury, L. & Prise, K. M., 31.01.2009, In: MUTAT RES-FUND MOL M. 672, 2, p. 82-9 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
gamma-H2AX as protein biomarker for radiation exposure
Rothkamm, K. & Horn, S., 2009, In: ANN I SUPER SANITA. 45, 3, p. 265-71 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2008
ATM acts downstream of ATR in the DNA damage response signaling of bystander cells
Burdak-Rothkamm, S., Rothkamm, K. & Prise, K. M., 01.09.2008, In: CANCER RES. 68, 17, p. 7059-65 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radiation-induced HPRT mutations resulting from misrejoined DNA double-strand breaks
Rothkamm, K., Gunasekara, K., Warda, S. A., Krempler, A. & Löbrich, M., 06.2008, In: RADIAT RES. 169, 6, p. 639-48 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Radiosensitization by nitric oxide at low radiation doses
Wardman, P., Rothkamm, K., Folkes, L. K., Woodcock, M. & Johnston, P. J., 04.2007, In: RADIAT RES. 167, 4, p. 475-84 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ATR-dependent radiation-induced gamma H2AX foci in bystander primary human astrocytes and glioma cells
Burdak-Rothkamm, S., Short, S. C., Folkard, M., Rothkamm, K. & Prise, K. M., 15.02.2007, In: ONCOGENE. 26, 7, p. 993-1002 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure
Rothkamm, K., Balroop, S., Shekhdar, J., Fernie, P. & Goh, V., 01.2007, In: RADIOLOGY. 242, 1, p. 244-51 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Radiation-induced transgenerational alterations in genome stability and DNA damage
Barber, R. C., Hickenbotham, P., Hatch, T., Kelly, D., Topchiy, N., Almeida, G. M., Jones, G. D. D., Johnson, G. E., Parry, J. M., Rothkamm, K. & Dubrova, Y. E., 30.11.2006, In: ONCOGENE. 25, 56, p. 7336-42 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity
Kühne, M., Riballo, E., Rief, N., Rothkamm, K., Jeggo, P. A. & Löbrich, M., 15.01.2004, In: CANCER RES. 64, 2, p. 500-8 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enhanced fidelity for rejoining radiation-induced DNA double-strand breaks in the G2 phase of Chinese hamster ovary cells
Krüger, I., Rothkamm, K. & Löbrich, M., 2004, In: NUCLEIC ACIDS RES. 32, 9, p. 2677-84 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Pathways of DNA double-strand break repair during the mammalian cell cycle
Rothkamm, K., Krüger, I., Thompson, L. H. & Löbrich, M., 08.2003, In: MOL CELL BIOL. 23, 16, p. 5706-15 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
Rothkamm, K. & Löbrich, M., 29.04.2003, In: P NATL ACAD SCI USA. 100, 9, p. 5057-62 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Misrepair of radiation-induced DNA double-strand breaks and its relevance for tumorigenesis and cancer treatment (review)
Rothkamm, K. & Löbrich, M., 08.2002, In: INT J ONCOL. 21, 2, p. 433-40 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Physical and biological parameters affecting DNA double strand break misrejoining in mammalian cells
Kühne, M., Rothkamm, K. & Löbrich, M., 2002, In: RADIAT PROT DOSIM. 99, 1-4, p. 129-32 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks
Rothkamm, K., Kühne, M., Jeggo, P. A. & Löbrich, M., 15.05.2001, In: CANCER RES. 61, 10, p. 3886-93 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
Formation and repair of DNA double-strand breaks in gamma-irradiated K562 cells undergoing erythroid differentiation
Tabocchini, M. A., Rothkamm, K., Signoretti, C., Risse, J., Sapora, O. & Löbrich, M., 15.09.2000, In: MUTAT RES-FUND MOL M. 461, 1, p. 71-82 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
No dose-dependence of DNA double-strand break misrejoining following alpha-particle irradiation
Kühne, M., Rothkamm, K. & Löbrich, M., 07.2000, In: INT J RADIAT BIOL. 76, 7, p. 891-900 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts
Löbrich, M., Kühne, M., Wetzel, J. & Rothkamm, K., 01.2000, In: GENE CHROMOSOME CANC. 27, 1, p. 59-68 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1999
Misrejoining of DNA double-strand breaks in primary and transformed human and rodent cells: a comparison between the HPRT region and other genomic locations
Rothkamm, K. & Löbrich, M., 09.04.1999, In: MUTAT RES-FUND MOL M. 433, 3, p. 193-205 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review