Prof. Dr. ID: 2375364

Kai Rothkamm

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Publications

  1. 2013
  2. Deoxyribonucleic acid damage-associated biomarkers of ionising radiation: current status and future relevance for radiology and radiotherapy

    Manning, G. & Rothkamm, K., 07.2013, In: BRIT J RADIOL. 86, 1027, p. 20130173

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  3. Homologous recombination mediates cellular resistance and fraction size sensitivity to radiation therapy

    Somaiah, N., Yarnold, J., Lagerqvist, A., Rothkamm, K. & Helleday, T., 07.2013, In: RADIOTHER ONCOL. 108, 1, p. 155-61 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. The shape of the radiation dose response for DNA double-strand break induction and repair

    Barnard, S., Bouffler, S. & Rothkamm, K., 22.03.2013, In: Genome integrity. 4, 1, p. 1

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome

    Gribble, S. M., Wiseman, F. K., Clayton, S., Prigmore, E., Langley, E., Yang, F., Maguire, S., Fu, B., Rajan, D., Sheppard, O., Scott, C., Hauser, H., Stephens, P. J., Stebbings, L. A., Ng, B. L., Fitzgerald, T., Quail, M. A., Banerjee, R., Rothkamm, K., Tybulewicz, V. L. J., Fisher, E. M. C. & Carter, N. P., 2013, In: PLOS ONE. 8, 4, p. e60482

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. 2012
  7. The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy

    Somaiah, N., Yarnold, J., Daley, F., Pearson, A., Gothard, L., Rothkamm, K. & Helleday, T., 01.10.2012, In: CLIN CANCER RES. 18, 19, p. 5479-88 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Ionizing radiation biomarkers for potential use in epidemiological studies

    Pernot, E., Hall, J., Baatout, S., Benotmane, M. A., Blanchardon, E., Bouffler, S., El Saghire, H., Gomolka, M., Guertler, A., Harms-Ringdahl, M., Jeggo, P., Kreuzer, M., Laurier, D., Lindholm, C., Mkacher, R., Quintens, R., Rothkamm, K., Sabatier, L., Tapio, S., de Vathaire, F. & Cardis, E., 09.06.2012, In: MUTAT RES-FUND MOL M. 751, 2, p. 258-86 29 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  9. In situ biological dose mapping estimates the radiation burden delivered to 'spared' tissue between synchrotron X-ray microbeam radiotherapy tracks

    Rothkamm, K., Crosbie, J. C., Daley, F., Bourne, S., Barber, P. R., Vojnovic, B., Cann, L. & Rogers, P. A. W., 2012, In: PLOS ONE. 7, 1, p. e29853

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. 2011
  11. Review of retrospective dosimetry techniques for external ionising radiation exposures

    Ainsbury, E. A., Bakhanova, E., Barquinero, J. F., Brai, M., Chumak, V., Correcher, V., Darroudi, F., Fattibene, P., Gruel, G., Guclu, I., Horn, S., Jaworska, A., Kulka, U., Lindholm, C., Lloyd, D., Longo, A., Marrale, M., Monteiro Gil, O., Oestreicher, U., Pajic, J., Rakic, B., Romm, H., Trompier, F., Veronese, I., Voisin, P., Vral, A., Whitehouse, C. A., Wieser, A., Woda, C., Wojcik, A. & Rothkamm, K., 11.2011, In: RADIAT PROT DOSIM. 147, 4, p. 573-92 20 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  12. Residual DNA and chromosomal damage in ex vivo irradiated blood lymphocytes correlated with late normal tissue response to breast radiotherapy

    Chua, M. L. K., Somaiah, N., A'Hern, R., Davies, S., Gothard, L., Yarnold, J. & Rothkamm, K., 06.2011, In: RADIOTHER ONCOL. 99, 3, p. 362-6 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Inter-individual and inter-cell type variation in residual DNA damage after in vivo irradiation of human skin

    Chua, M. L. K., Somaiah, N., Bourne, S., Daley, F., A'hern, R., Nuta, O., Davies, S., Herskind, C., Pearson, A., Warrington, J., Helyer, S., Owen, R., Yarnold, J. & Rothkamm, K., 05.2011, In: RADIOTHER ONCOL. 99, 2, p. 225-30 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Triage, monitoring and dose assessment for people exposed to ionising radiation following a malevolent act

    Etherington, G., Rothkamm, K., Shutt, A. L. & Youngman, M. J., 03.2011, In: RADIAT PROT DOSIM. 144, 1-4, p. 534-9 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells

    Bauerschmidt, C., Woodcock, M., Stevens, D. L., Hill, M. A., Rothkamm, K. & Helleday, T., 01.02.2011, In: EXP CELL RES. 317, 3, p. 330-7 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Gamma-H2AX-based dose estimation for whole and partial body radiation exposure

    Horn, S., Barnard, S. & Rothkamm, K., 2011, In: PLOS ONE. 6, 9, p. e25113

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Ionizing radiation-induced DNA strand breaks and γ-H2AXγ-H2AX foci in cells exposed to nitric oxide

    Rothkamm, K. & Burdak-Rothkamm, S., 2011, In: Methods Mol Biol. 704, p. 17-25 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. 2010
  19. Limitations associated with analysis of cytogenetic data for biological dosimetry

    Vinnikov, V. A., Ainsbury, E. A., Maznyk, N. A., Lloyd, D. C. & Rothkamm, K., 10.2010, In: RADIAT RES. 174, 4, p. 403-14 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  20. Tumor cell response to synchrotron microbeam radiation therapy differs markedly from cells in normal tissues

    Crosbie, J. C., Anderson, R. L., Rothkamm, K., Restall, C. M., Cann, L., Ruwanpura, S., Meachem, S., Yagi, N., Svalbe, I., Lewis, R. A., Williams, B. R. G. & Rogers, P. A. W., 01.07.2010, In: INT J RADIAT ONCOL. 77, 3, p. 886-94 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin

    Bauerschmidt, C., Arrichiello, C., Burdak-Rothkamm, S., Woodcock, M., Hill, M. A., Stevens, D. L. & Rothkamm, K., 01.2010, In: NUCLEIC ACIDS RES. 38, 2, p. 477-87 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. 2009
  23. Interlaboratory variation in scoring dicentric chromosomes in a case of partial-body x-ray exposure: implications for biodosimetry networking and cytogenetic "triage mode" scoring

    Ainsbury, E. A., Livingston, G. K., Abbott, M. G., Moquet, J. E., Hone, P. A., Jenkins, M. S., Christensen, D. M., Lloyd, D. C. & Rothkamm, K., 12.2009, In: RADIAT RES. 172, 6, p. 746-52 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. DNA and chromosomal damage in response to intermittent extremely low-frequency magnetic fields

    Burdak-Rothkamm, S., Rothkamm, K., Folkard, M., Patel, G., Hone, P., Lloyd, D., Ainsbury, L. & Prise, K. M., 31.01.2009, In: MUTAT RES-FUND MOL M. 672, 2, p. 82-9 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. gamma-H2AX as protein biomarker for radiation exposure

    Rothkamm, K. & Horn, S., 2009, In: ANN I SUPER SANITA. 45, 3, p. 265-71 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  26. 2008
  27. ATM acts downstream of ATR in the DNA damage response signaling of bystander cells

    Burdak-Rothkamm, S., Rothkamm, K. & Prise, K. M., 01.09.2008, In: CANCER RES. 68, 17, p. 7059-65 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Radiation-induced HPRT mutations resulting from misrejoined DNA double-strand breaks

    Rothkamm, K., Gunasekara, K., Warda, S. A., Krempler, A. & Löbrich, M., 06.2008, In: RADIAT RES. 169, 6, p. 639-48 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. 2007
  30. Radiosensitization by nitric oxide at low radiation doses

    Wardman, P., Rothkamm, K., Folkes, L. K., Woodcock, M. & Johnston, P. J., 04.2007, In: RADIAT RES. 167, 4, p. 475-84 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. ATR-dependent radiation-induced gamma H2AX foci in bystander primary human astrocytes and glioma cells

    Burdak-Rothkamm, S., Short, S. C., Folkard, M., Rothkamm, K. & Prise, K. M., 15.02.2007, In: ONCOGENE. 26, 7, p. 993-1002 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure

    Rothkamm, K., Balroop, S., Shekhdar, J., Fernie, P. & Goh, V., 01.2007, In: RADIOLOGY. 242, 1, p. 244-51 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. 2006
  34. Radiation-induced transgenerational alterations in genome stability and DNA damage

    Barber, R. C., Hickenbotham, P., Hatch, T., Kelly, D., Topchiy, N., Almeida, G. M., Jones, G. D. D., Johnson, G. E., Parry, J. M., Rothkamm, K. & Dubrova, Y. E., 30.11.2006, In: ONCOGENE. 25, 56, p. 7336-42 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. 2004
  36. A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

    Kühne, M., Riballo, E., Rief, N., Rothkamm, K., Jeggo, P. A. & Löbrich, M., 15.01.2004, In: CANCER RES. 64, 2, p. 500-8 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Enhanced fidelity for rejoining radiation-induced DNA double-strand breaks in the G2 phase of Chinese hamster ovary cells

    Krüger, I., Rothkamm, K. & Löbrich, M., 2004, In: NUCLEIC ACIDS RES. 32, 9, p. 2677-84 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. 2003
  39. Pathways of DNA double-strand break repair during the mammalian cell cycle

    Rothkamm, K., Krüger, I., Thompson, L. H. & Löbrich, M., 08.2003, In: MOL CELL BIOL. 23, 16, p. 5706-15 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

    Rothkamm, K. & Löbrich, M., 29.04.2003, In: P NATL ACAD SCI USA. 100, 9, p. 5057-62 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. 2002
  42. Misrepair of radiation-induced DNA double-strand breaks and its relevance for tumorigenesis and cancer treatment (review)

    Rothkamm, K. & Löbrich, M., 08.2002, In: INT J ONCOL. 21, 2, p. 433-40 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  43. Physical and biological parameters affecting DNA double strand break misrejoining in mammalian cells

    Kühne, M., Rothkamm, K. & Löbrich, M., 2002, In: RADIAT PROT DOSIM. 99, 1-4, p. 129-32 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. 2001
  45. Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks

    Rothkamm, K., Kühne, M., Jeggo, P. A. & Löbrich, M., 15.05.2001, In: CANCER RES. 61, 10, p. 3886-93 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. 2000
  47. Formation and repair of DNA double-strand breaks in gamma-irradiated K562 cells undergoing erythroid differentiation

    Tabocchini, M. A., Rothkamm, K., Signoretti, C., Risse, J., Sapora, O. & Löbrich, M., 15.09.2000, In: MUTAT RES-FUND MOL M. 461, 1, p. 71-82 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. No dose-dependence of DNA double-strand break misrejoining following alpha-particle irradiation

    Kühne, M., Rothkamm, K. & Löbrich, M., 07.2000, In: INT J RADIAT BIOL. 76, 7, p. 891-900 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts

    Löbrich, M., Kühne, M., Wetzel, J. & Rothkamm, K., 01.2000, In: GENE CHROMOSOME CANC. 27, 1, p. 59-68 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. 1999
  51. Misrejoining of DNA double-strand breaks in primary and transformed human and rodent cells: a comparison between the HPRT region and other genomic locations

    Rothkamm, K. & Löbrich, M., 09.04.1999, In: MUTAT RES-FUND MOL M. 433, 3, p. 193-205 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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