PD Dr. med. ID: 3642715
Ivayla Apostolova
Publications
- 2024
Decreased mebrofenin uptake in patients with non-colorectal liver tumors requiring liver volume augmentation-a single-center analysis
Fard-Aghaie, M. H., Stern, L., Ghadban, T., Apostolova, I., Lehnert, W., Klutmann, S., Hackert, T., Izbicki, J. R., Li, J., von Kroge, P. H. & Heumann, A., 11.03.2024, In: LANGENBECK ARCH SURG. 409, 1, p. 92Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prostate-specific membrane antigen radioguided surgery with negative histopathology
Koehler, D., Trappe, S., Shenas, F., Karimzadeh, A., Apostolova, I., Klutmann, S., Ambrosini, F., Budäus, L., Falkenbach, F., Knipper, S. & Maurer, T., 01.2024, In: EUR J NUCL MED MOL I. 51, 2, p. 548-557 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Asymmetry of thalamic hypometabolism on FDG-PET/CT in neurofibromatosis type 1: Association with peripheral tumor burden
Özden, C., Mautner, V-F., Farschtschi, S., Molwitz, I., Ristow, I., Bannas, P., Well, L., Klutmann, S., Adam, G., Apostolova, I. & Buchert, R., 2024, In: J NEUROIMAGING. 34, 1, p. 138-144 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
PSMA hybrid imaging in prostate cancer - current applications and perspectives
Koehler, D., Berliner, C., Shenas, F., Karimzadeh, A., Apostolova, I., Klutmann, S., Adam, G. & Sauer, M., 11.2023, In: ROFO-FORTSCHR RONTG. 195, 11, p. 1001-1008 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Automatic covariance pattern analysis outperforms visual reading of 18 F-fluorodeoxyglucose-positron emission tomography (FDG-PET) in variant progressive supranuclear palsy
Buchert, R., Wegner, F., Huppertz, H-J., Berding, G., Brendel, M., Apostolova, I., Buhmann, C., Dierks, A., Katzdobler, S., Klietz, M., Levin, J., Mahmoudi, N., Rinscheid, A., Rogozinski, S., Rumpf, J-J., Schneider, C., Stöcklein, S., Spetsieris, P. G., Eidelberg, D., Wattjes, M. P., Sabri, O., Barthel, H., Höglinger, G. & Alzheimer’s Disease Neuroimaging Initiative, 27.10.2023, In: MOVEMENT DISORD. 38, 10, p. 1901-1913 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brain MRI in Progressive Supranuclear Palsy with Richardson's Syndrome and Variant Phenotypes
Wattjes, M. P., Huppertz, H-J., Mahmoudi, N., Stöcklein, S., Rogozinski, S., Wegner, F., Klietz, M., Apostolova, I., Levin, J., Katzdobler, S., Buhmann, C., Quattrone, A., Berding, G., Brendel, M., Barthel, H., Sabri, O., Höglinger, G., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 27.10.2023, In: MOVEMENT DISORD. 38, 10, p. 1891-1900 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
No impact of attenuation and scatter correction on the interpretation of dopamine transporter SPECT in patients with clinically uncertain parkinsonian syndrome
Schiebler, T., Apostolova, I., Mathies, F. L., Lange, C., Klutmann, S. & Buchert, R., 09.2023, In: EUR J NUCL MED MOL I. 50, 11, p. 3302-3312 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients
Mäurer, A., Himmel, G., Lange, C., Mathies, F., Apostolova, I., Peters, O. & Buchert, R., 31.07.2023, In: J ALZHEIMERS DIS. 94, 2, p. 559-584 26 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stereotactical normalization with multiple templates representative of normal and Parkinson-typical reduction of striatal uptake improves the discriminative power of automatic semi-quantitative analysis in dopamine transporter SPECT
Apostolova, I., Schiebler, T., Lange, C., Mathies, F. L., Lehnert, W., Klutmann, S. & Buchert, R., 29.03.2023, In: EJNMMI PHYS. 10, 1, p. 25Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Feasibility of 99m Tc-MIP-1404 for SPECT/CT imaging and subsequent PSMA-radioguided surgery in early biochemical recurrent prostate cancer: a case series of 9 patients
Köhler, D., Sauer, M., Klutmann, S., Apostolova, I., Lehnert, W., Budäus, L., Knipper, S. & Maurer, T., 01.2023, In: J NUCL MED. 64, 1, p. 59-62 4 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
- 2022
Evaluation of [68 Ga]Ga-PSMA-I&T PET/CT with additional late scans of the pelvis in prostate-specific antigen recurrence using the PROMISE criteria
Koehler, D., Sauer, M., Karimzadeh, A., Apostolova, I., Klutmann, S., Adam, G., Knipper, S., Maurer, T. & Berliner, C., 09.10.2022, In: EJNMMI RES. 12, 1, 66.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiple-pinhole collimators improve intra- and between-rater agreement and the certainty of the visual interpretation in dopamine transporter SPECT
Mathies, F., Apostolova, I., Dierck, L., Jacobi, J., Kuen, K., Sauer, M., Schenk, M., Klutmann, S., Forgács, A. & Buchert, R., 17.08.2022, In: EJNMMI RES. 12, 1, p. 51 51.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Predicting the outcome of epilepsy surgery by covariance pattern analysis of ictal perfusion SPECT
Taherpour, J., Jaber, M., Voges, B., Apostolova, I., Sauvigny, T., House, P. M., Lanz, M., Lindenau, M., Klutmann, S., Martens, T., Stodieck, S. & Buchert, R., 06.2022, In: J NUCL MED. 63, 6, p. 925-930 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stereotactical Normalization with Multiple Templates Representative of Normal and Parkinson-Typical Reduction of Striatal Uptake Improves the Diagnostic Power of Automatic Semi-Quantitative Analysis in Dopamine Transporter SPECT
Apostolova, I., Schiebler, T., Lange, C., Mathies, F. L., Lehnert, W., Klutmann, S. & Buchert, R., 28.03.2022Research output: Other contribution › Other › Research
Explainable AI to improve acceptance of convolutional neural networks for automatic classification of dopamine transporter SPECT in the diagnosis of clinically uncertain parkinsonian syndromes
Nazari, M., Kluge, A., Apostolova, I., Klutmann, S., Kimiaei, S., Schroeder, M. & Buchert, R., 03.2022, In: EUR J NUCL MED MOL I. 49, 4, p. 1176-1186 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brain FDG PET for Short- to Medium-Term Prediction of Further Cognitive Decline and Need for Assisted Living in Acutely Hospitalized Geriatric Patients With Newly Detected Clinically Uncertain Cognitive Impairment
Lange, C., Mäurer, A., Suppa, P., Apostolova, I., Steffen, I. G., Grothe, M. J. & Buchert, R., 01.02.2022, In: CLIN NUCL MED. 47, 2, p. 123-129 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Clinical impact of whole-body 68Ga-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities
Stolzenbach, L. F., Löcherbach, F., Wargenau, K., Pose, R., Steuber, T., Tian, Z., Budäus, L., Tilki, D., Graefen, M., Köhler, D., Karakiewicz, P. I., Sauer, M., Apostolova, I. I., Maurer, T. & Berliner, C., 12.2021, In: NUKLEARMED-NUCL MED. 60, 6, p. 417-424 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Data-driven identification of diagnostically useful extrastriatal signal in dopamine transporter SPECT using explainable AI
Nazari, M., Kluge, A., Apostolova, I., Klutmann, S., Kimiaei, S., Schroeder, M. & Buchert, R., 25.11.2021, In: SCI REP-UK. 11, 1, 22932.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
No Evidence to Favor 99mTc-HMPAO or 99mTc-ECD for Ictal Brain Perfusion SPECT for Identification of the Seizure Onset Zone
Jaber, M., Taherpour, J., Voges, B., Apostolova, I., Sauvigny, T., House, P. M., Lanz, M., Lindenau, M., Klutmann, S., Martens, T., Stodieck, S. & Buchert, R., 01.11.2021, In: CLIN NUCL MED. 46, 11, p. 890-895 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of age and sex correction on the diagnostic performance of dopamine transporter SPECT
Schmitz-Steinkrüger, H., Lange, C., Apostolova, I., Mathies, F. L., Frings, L., Klutmann, S., Hellwig, S., Meyer, P. T. & Buchert, R., 05.2021, In: EUR J NUCL MED MOL I. 48, 5, p. 1445-1459 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Performance evaluation of a novel multi-pinhole collimator for dopamine transporter SPECT
Tecklenburg, K., Forgács, A., Apostolova, I., Lehnert, W., Klutmann, S., Csirik, J., Garutti, E. & Buchert, R., 21.08.2020, In: PHYS MED BIOL. 65, 16, p. 165015Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of the size of the normal database on the performance of the specific binding ratio in dopamine transporter SPECT
Schmitz-Steinkrüger, H., Lange, C., Apostolova, I., Amthauer, H., Lehnert, W., Klutmann, S. & Buchert, R., 20.05.2020, In: EJNMMI PHYS. 7, 1, p. 34Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Corrigendum: The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study
Perosa, V., de Boer, L., Ziegler, G., Apostolova, I., Buchert, R., Metzger, C., Amthauer, H., Guitart-Masip, M., Düzel, E. & Betts, M. J., 18.05.2020, In: CEREB CORTEX. 30, 6, 3857.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study
Perosa, V., de Boer, L., Ziegler, G., Apostolova, I., Buchert, R., Metzger, C., Amthauer, H., Guitart-Masip, M., Düzel, E. & Betts, M. J., 14.05.2020, In: CEREB CORTEX. 30, 5, p. 3340-3351 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Older adults show a reduced tendency to engage in context-dependent decision biases
Sablotny-Wackershauser, V., Betts, M. J., Brunnlieb, C., Apostolova, I., Buchert, R., Düzel, E., Gruendler, T. O. J. & Vogt, B., 05.2020, In: NEUROPSYCHOLOGIA. 142, p. 107445Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
FDG Uptake in the Basal Forebrain as Measured by Digital High-Resolution PET Is a Promising Marker of Basal Forebrain Degeneration in the Lewy Body Disease Spectrum: A Pilot Study
Özden, C., Frings, L., Apostolova, I., Lange, C., Klutmann, S., Adam, G., Bannas, P., Meyer, P. T., Grothe, M. J. & Buchert, R., 04.2020, In: CLIN NUCL MED. 45, 4, p. 261-266 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nigrostriatal Degeneration in the Cognitive Part of the Striatum in Parkinson Disease Is Associated With Frontomedial Hypometabolism
Apostolova, I., Lange, C., Frings, L., Klutmann, S., Meyer, P. T. & Buchert, R., 02.2020, In: CLIN NUCL MED. 45, 2, p. 95-99 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brain FDG PET for the Etiological Diagnosis of Clinically Uncertain Cognitive Impairment During Delirium in Remission
Mathies, F., Lange, C., Mäurer, A., Apostolova, I., Klutmann, S. & Buchert, R., 2020, In: J ALZHEIMERS DIS. 77, 4, p. 1609-1622 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impairment of Everyday Spatial Navigation Abilities in Mild Cognitive Impairment Is Weakly Associated with Reduced Grey Matter Volume in the Medial Part of the Entorhinal Cortex
Hallab, A., Lange, C., Apostolova, I., Özden, C., Gonzalez-Escamilla, G., Klutmann, S., Brenner, W., Grothe, M. J., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 2020, In: J ALZHEIMERS DIS. 78, 3, p. 1149-1159 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Automatic classification of dopamine transporter SPECT: deep convolutional neural networks can be trained to be robust with respect to variable image characteristics
Wenzel, M., Milletari, F., Krüger, J., Lange, C., Schenk, M., Apostolova, I., Klutmann, S., Ehrenburg, M. & Buchert, R., 12.2019, In: EUR J NUCL MED MOL I. 46, 13, p. 2800-2811 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nuclear Imaging in the Diagnosis of Clinically Uncertain Parkinsonian Syndromes
Buchert, R., Buhmann, C., Apostolova, I., Meyer, P. T. & Gallinat, J., 01.11.2019, In: DTSCH ARZTEBL INT. 116, 44, p. 747-754 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis
Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K. T., Fragoulis, A., Kühl, A. A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C. E., Brenner, W., Malinowski, M. B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O. J., Tacke, F., Morkel, M. & Cramer, T., 07.2019, In: ONCOGENE. 38, 28, p. 5670-5685 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic performance of the specific uptake size index for semi-quantitative analysis of I-123-FP-CIT SPECT: harmonized multi-center research setting versus typical clinical single-camera setting
Buchert, R., Lange, C., Spehl, T. S., Apostolova, I., Frings, L., Jonsson, C., Meyer, P. T. & Hellwig, S., 07.05.2019, In: EJNMMI RES. 9, 1, p. 37Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interobserver variability of image-derived arterial blood SUV in whole-body FDG PET
Hofheinz, F., Maus, J., Zschaeck, S., Rogasch, J., Schramm, G., Oehme, L., Apostolova, I., Kotzerke, J. & den Hoff, J. V., 04.03.2019, In: EJNMMI RES. 9, 1, p. 23Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical impact of “true whole-body” Ga-68-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities
Stolzenbach, F., Maurer, T., Budäus, L., Steuber, T., Graefen, M., Sauer, M., Kobayashi, Y., Apostolova, I. & Berliner, C., 2019, In: NUKLEARMED-NUCL MED. 58, 02, p. P16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection rate of Tc-99 m-PSMA I&S SPECT/CT in comparison to Ga-68-PSMA PET/CT in patients with biochemically recurrent prostate cancer planned for radioguided surgery
Berliner, C., Sauer, M., Kobayashi, Y., Buchert, R., Mester, J., Maurer, T., Stolzenbach, F., Wester, HJ., Apostolova, I. & Bannas, P., 2019, In: NUKLEARMED-NUCL MED. 58, 02, p. P9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Feasibility of cardiac preparation protocol in the diagnostic of endocarditis with FDG-PET CT in clinical routine
Berliner, C., Sauer, M., Buchert, R., Mester, J., Adam, G., Klutmann, S. & Apostolova, I., 2019, In: NUKLEARMED-NUCL MED. 58, 02, p. P118Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The association of intra-therapeutic heterogeneity of somatostatin receptor expression with morphological treatment response in patients undergoing PRRT with [177Lu]-DOTATATE
Wetz, C., Genseke, P., Apostolova, I., Furth, C., Ghazzawi, S., Rogasch, J. M. M., Schatka, I., Kreissl, M. C., Hofheinz, F., Grosser, O. S. & Amthauer, H., 2019, In: PLOS ONE. 14, 5, p. e0216781Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vergleich von Tc-99 m-PSMA I&S SPECT/CT und Ga-68-PSMA PET/CT vor Gammasonden-gesteuerter Operation bei Prostatakarzinomrezidiv
Stolzenbach, F., Sauer, M., Kobayashi, Y., Buchert, R., Mester, J., Maurer, T., Wester, H., Apostolova, I., Bannas, P. & Berliner, C., 2019, In: ROFO-FORTSCHR RONTG. 191, S 01, p. WISS 401.5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Impact of plasma glucose level on the pattern of brain FDG uptake and the predictive power of FDG PET in mild cognitive impairment
Apostolova, I., Lange, C., Suppa, P., Spies, L., Klutmann, S., Adam, G., Grothe, M. J., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 07.2018, In: EUR J NUCL MED MOL I. 45, 8, p. 1417-1422 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Magnetic resonance imaging-based hippocampus volume for prediction of dementia in mild cognitive impairment: Why does the measurement method matter so little?
Buchert, R., Lange, C., Suppa, P., Apostolova, I., Spies, L., Teipel, S., Dubois, B., Hampel, H. & Grothe, M. J., 07.2018, In: ALZHEIMERS DEMENT. 14, 7, p. 976-978 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Monitoring scanner calibration using the image-derived arterial blood SUV in whole-body FDG-PET
Maus, J., Hofheinz, F., Apostolova, I., Kreissl, M. C., Kotzerke, J. & van den Hoff, J., 15.05.2018, In: EJNMMI RES. 8, 1, p. 38Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypermetabolism in the hippocampal formation of cognitively impaired patients indicates detrimental maladaptation
Apostolova, I., Lange, C., Mäurer, A., Suppa, P., Spies, L., Grothe, M. J., Nierhaus, T., Fiebach, J. B., Steinhagen-Thiessen, E., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 05.2018, In: NEUROBIOL AGING. 65, p. 41-50 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Test-retest variability of lesion SUV and lesion SUR in (18)F-FDG PET: an analysis of data from two prospective multicenter trials
Hofheinz, F., Apostolova, I., Oehme, L., Kotzerke, J. & van den Hoff, J., 11.2017, In: J NUCL MED. 58, 11, p. 1770-1775Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Utility of Follow-up Dopamine Transporter SPECT With 123I-FP-CIT in the Diagnostic Workup of Patients With Clinically Uncertain Parkinsonian Syndrome
Apostolova, I., Taleb, D. S., Lipp, A., Galazky, I., Kupitz, D., Lange, C., Makowski, M. R., Brenner, W., Amthauer, H., Plotkin, M. & Buchert, R., 08.2017, In: CLIN NUCL MED. 42, 8, p. 589-594 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Predictive Value of Asphericity in Pretherapeutic [(111)In]DTPA-Octreotide SPECT/CT for Response to Peptide Receptor Radionuclide Therapy with [(177)Lu]DOTATATE
Wetz, C., Apostolova, I., Steffen, I. G., Hofheinz, F., Furth, C., Kupitz, D., Ruf, J., Venerito, M., Klose, S. & Amthauer, H., 06.2017, In: MOL IMAGING BIOL. 19, 3, p. 437-445 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of obstructive uropathy and assessment of differential renal function using two functional magnetic resonance urography tools. A comparison with diuretic renal scintigraphy in infants and children
Genseke, P., Rogasch, J. M. M., Steffen, I. G., Neumann, G., Apostolova, I., Ruf, J., Rißmann, A., Wiemann, D., Liehr, U-B., Schostak, M., Amthauer, H. & Furth, C., 14.02.2017, In: NUKLEARMED-NUCL MED. 56, 1, p. 39-46 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Challenges in Screening and Recruitment for a Neuroimaging Study in Cognitively Impaired Geriatric Inpatients
Apostolova, I., Lange, C., Roberts, A., Igel, H. J., Mäurer, A., Liese, S., Estrella, M., Prasad, V., Stechl, E., Lämmler, G., Steinhagen-Thiessen, E. & Buchert, R., 2017, In: J ALZHEIMERS DIS. 56, 1, p. 197-204 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Software-assisted dosimetry in peptide receptor radionuclide therapy with 177Lutetium-DOTATATE for various imaging scenarios
Kupitz, D., Wetz, C., Wissel, H., Wedel, F., Apostolova, I., Wallbaum, T., Ricke, J., Amthauer, H. & Grosser, O. S., 2017, In: PLOS ONE. 12, 11, p. e0187570Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET
Hofheinz, F., Bütof, R., Apostolova, I., Zöphel, K., Steffen, I. G., Amthauer, H., Kotzerke, J., Baumann, M. & van den Hoff, J., 12.2016, In: EJNMMI RES. 6, 1, p. 19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review