PD Dr. med. ID: 3642715

Ivayla Apostolova

graph of relations

Publications

  1. 2024
  2. Prostate-specific membrane antigen radioguided surgery with negative histopathology

    Koehler, D., Trappe, S., Shenas, F., Karimzadeh, A., Apostolova, I., Klutmann, S., Ambrosini, F., Budäus, L., Falkenbach, F., Knipper, S. & Maurer, T., 01.2024, In: EUR J NUCL MED MOL I. 51, 2, p. 548-557 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Asymmetry of thalamic hypometabolism on FDG-PET/CT in neurofibromatosis type 1: Association with peripheral tumor burden

    Özden, C., Mautner, V-F., Farschtschi, S., Molwitz, I., Ristow, I., Bannas, P., Well, L., Klutmann, S., Adam, G., Apostolova, I. & Buchert, R., 2024, In: J NEUROIMAGING. 34, 1, p. 138-144 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. 2023
  5. PSMA hybrid imaging in prostate cancer - current applications and perspectives

    Koehler, D., Berliner, C., Shenas, F., Karimzadeh, A., Apostolova, I., Klutmann, S., Adam, G. & Sauer, M., 11.2023, In: ROFO-FORTSCHR RONTG. 195, 11, p. 1001-1008 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  6. Automatic covariance pattern analysis outperforms visual reading of 18 F-fluorodeoxyglucose-positron emission tomography (FDG-PET) in variant progressive supranuclear palsy

    Buchert, R., Wegner, F., Huppertz, H-J., Berding, G., Brendel, M., Apostolova, I., Buhmann, C., Dierks, A., Katzdobler, S., Klietz, M., Levin, J., Mahmoudi, N., Rinscheid, A., Rogozinski, S., Rumpf, J-J., Schneider, C., Stöcklein, S., Spetsieris, P. G., Eidelberg, D., Wattjes, M. P., Sabri, O., Barthel, H., Höglinger, G. & Alzheimer’s Disease Neuroimaging Initiative, 27.10.2023, In: MOVEMENT DISORD. 38, 10, p. 1901-1913 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Brain MRI in Progressive Supranuclear Palsy with Richardson's Syndrome and Variant Phenotypes

    Wattjes, M. P., Huppertz, H-J., Mahmoudi, N., Stöcklein, S., Rogozinski, S., Wegner, F., Klietz, M., Apostolova, I., Levin, J., Katzdobler, S., Buhmann, C., Quattrone, A., Berding, G., Brendel, M., Barthel, H., Sabri, O., Höglinger, G., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 27.10.2023, In: MOVEMENT DISORD. 38, 10, p. 1891-1900 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. No impact of attenuation and scatter correction on the interpretation of dopamine transporter SPECT in patients with clinically uncertain parkinsonian syndrome

    Schiebler, T., Apostolova, I., Mathies, F. L., Lange, C., Klutmann, S. & Buchert, R., 09.2023, In: EUR J NUCL MED MOL I. 50, 11, p. 3302-3312 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Individualized Summary Assessment of Detailed Neuropsychological Testing for the Etiological Diagnosis of Newly Detected Cognitive Impairment in Hospitalized Geriatric Patients

    Mäurer, A., Himmel, G., Lange, C., Mathies, F., Apostolova, I., Peters, O. & Buchert, R., 31.07.2023, In: J ALZHEIMERS DIS. 94, 2, p. 559-584 26 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Feasibility of 99m Tc-MIP-1404 for SPECT/CT imaging and subsequent PSMA-radioguided surgery in early biochemical recurrent prostate cancer: a case series of 9 patients

    Köhler, D., Sauer, M., Klutmann, S., Apostolova, I., Lehnert, W., Budäus, L., Knipper, S. & Maurer, T., 01.2023, In: J NUCL MED. 64, 1, p. 59-62 4 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  11. 2022
  12. Evaluation of [68 Ga]Ga-PSMA-I&T PET/CT with additional late scans of the pelvis in prostate-specific antigen recurrence using the PROMISE criteria

    Koehler, D., Sauer, M., Karimzadeh, A., Apostolova, I., Klutmann, S., Adam, G., Knipper, S., Maurer, T. & Berliner, C., 09.10.2022, In: EJNMMI RES. 12, 1, 66.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Multiple-pinhole collimators improve intra- and between-rater agreement and the certainty of the visual interpretation in dopamine transporter SPECT

    Mathies, F., Apostolova, I., Dierck, L., Jacobi, J., Kuen, K., Sauer, M., Schenk, M., Klutmann, S., Forgács, A. & Buchert, R., 17.08.2022, In: EJNMMI RES. 12, 1, p. 51 51.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Predicting the outcome of epilepsy surgery by covariance pattern analysis of ictal perfusion SPECT

    Taherpour, J., Jaber, M., Voges, B., Apostolova, I., Sauvigny, T., House, P. M., Lanz, M., Lindenau, M., Klutmann, S., Martens, T., Stodieck, S. & Buchert, R., 06.2022, In: J NUCL MED. 63, 6, p. 925-930 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Explainable AI to improve acceptance of convolutional neural networks for automatic classification of dopamine transporter SPECT in the diagnosis of clinically uncertain parkinsonian syndromes

    Nazari, M., Kluge, A., Apostolova, I., Klutmann, S., Kimiaei, S., Schroeder, M. & Buchert, R., 03.2022, In: EUR J NUCL MED MOL I. 49, 4, p. 1176-1186 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Brain FDG PET for Short- to Medium-Term Prediction of Further Cognitive Decline and Need for Assisted Living in Acutely Hospitalized Geriatric Patients With Newly Detected Clinically Uncertain Cognitive Impairment

    Lange, C., Mäurer, A., Suppa, P., Apostolova, I., Steffen, I. G., Grothe, M. J. & Buchert, R., 01.02.2022, In: CLIN NUCL MED. 47, 2, p. 123-129 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. 2021
  18. Clinical impact of whole-body 68Ga-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities

    Stolzenbach, L. F., Löcherbach, F., Wargenau, K., Pose, R., Steuber, T., Tian, Z., Budäus, L., Tilki, D., Graefen, M., Köhler, D., Karakiewicz, P. I., Sauer, M., Apostolova, I. I., Maurer, T. & Berliner, C., 12.2021, In: NUKLEARMED-NUCL MED. 60, 6, p. 417-424 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Data-driven identification of diagnostically useful extrastriatal signal in dopamine transporter SPECT using explainable AI

    Nazari, M., Kluge, A., Apostolova, I., Klutmann, S., Kimiaei, S., Schroeder, M. & Buchert, R., 25.11.2021, In: SCI REP-UK. 11, 1, 22932.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. No Evidence to Favor 99mTc-HMPAO or 99mTc-ECD for Ictal Brain Perfusion SPECT for Identification of the Seizure Onset Zone

    Jaber, M., Taherpour, J., Voges, B., Apostolova, I., Sauvigny, T., House, P. M., Lanz, M., Lindenau, M., Klutmann, S., Martens, T., Stodieck, S. & Buchert, R., 01.11.2021, In: CLIN NUCL MED. 46, 11, p. 890-895 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Impact of age and sex correction on the diagnostic performance of dopamine transporter SPECT

    Schmitz-Steinkrüger, H., Lange, C., Apostolova, I., Mathies, F. L., Frings, L., Klutmann, S., Hellwig, S., Meyer, P. T. & Buchert, R., 05.2021, In: EUR J NUCL MED MOL I. 48, 5, p. 1445-1459 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. 2020
  23. Performance evaluation of a novel multi-pinhole collimator for dopamine transporter SPECT

    Tecklenburg, K., Forgács, A., Apostolova, I., Lehnert, W., Klutmann, S., Csirik, J., Garutti, E. & Buchert, R., 21.08.2020, In: PHYS MED BIOL. 65, 16, p. 165015

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Impact of the size of the normal database on the performance of the specific binding ratio in dopamine transporter SPECT

    Schmitz-Steinkrüger, H., Lange, C., Apostolova, I., Amthauer, H., Lehnert, W., Klutmann, S. & Buchert, R., 20.05.2020, In: EJNMMI PHYS. 7, 1, p. 34

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Corrigendum: The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study

    Perosa, V., de Boer, L., Ziegler, G., Apostolova, I., Buchert, R., Metzger, C., Amthauer, H., Guitart-Masip, M., Düzel, E. & Betts, M. J., 18.05.2020, In: CEREB CORTEX. 30, 6, 3857.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  26. The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study

    Perosa, V., de Boer, L., Ziegler, G., Apostolova, I., Buchert, R., Metzger, C., Amthauer, H., Guitart-Masip, M., Düzel, E. & Betts, M. J., 14.05.2020, In: CEREB CORTEX. 30, 5, p. 3340-3351 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Older adults show a reduced tendency to engage in context-dependent decision biases

    Sablotny-Wackershauser, V., Betts, M. J., Brunnlieb, C., Apostolova, I., Buchert, R., Düzel, E., Gruendler, T. O. J. & Vogt, B., 05.2020, In: NEUROPSYCHOLOGIA. 142, p. 107445

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. FDG Uptake in the Basal Forebrain as Measured by Digital High-Resolution PET Is a Promising Marker of Basal Forebrain Degeneration in the Lewy Body Disease Spectrum: A Pilot Study

    Özden, C., Frings, L., Apostolova, I., Lange, C., Klutmann, S., Adam, G., Bannas, P., Meyer, P. T., Grothe, M. J. & Buchert, R., 04.2020, In: CLIN NUCL MED. 45, 4, p. 261-266 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Nigrostriatal Degeneration in the Cognitive Part of the Striatum in Parkinson Disease Is Associated With Frontomedial Hypometabolism

    Apostolova, I., Lange, C., Frings, L., Klutmann, S., Meyer, P. T. & Buchert, R., 02.2020, In: CLIN NUCL MED. 45, 2, p. 95-99 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Brain FDG PET for the Etiological Diagnosis of Clinically Uncertain Cognitive Impairment During Delirium in Remission

    Mathies, F., Lange, C., Mäurer, A., Apostolova, I., Klutmann, S. & Buchert, R., 2020, In: J ALZHEIMERS DIS. 77, 4, p. 1609-1622 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Impairment of Everyday Spatial Navigation Abilities in Mild Cognitive Impairment Is Weakly Associated with Reduced Grey Matter Volume in the Medial Part of the Entorhinal Cortex

    Hallab, A., Lange, C., Apostolova, I., Özden, C., Gonzalez-Escamilla, G., Klutmann, S., Brenner, W., Grothe, M. J., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 2020, In: J ALZHEIMERS DIS. 78, 3, p. 1149-1159 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. 2019
  33. Automatic classification of dopamine transporter SPECT: deep convolutional neural networks can be trained to be robust with respect to variable image characteristics

    Wenzel, M., Milletari, F., Krüger, J., Lange, C., Schenk, M., Apostolova, I., Klutmann, S., Ehrenburg, M. & Buchert, R., 12.2019, In: EUR J NUCL MED MOL I. 46, 13, p. 2800-2811 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Nuclear Imaging in the Diagnosis of Clinically Uncertain Parkinsonian Syndromes

    Buchert, R., Buhmann, C., Apostolova, I., Meyer, P. T. & Gallinat, J., 01.11.2019, In: DTSCH ARZTEBL INT. 116, 44, p. 747-754 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis

    Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K. T., Fragoulis, A., Kühl, A. A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C. E., Brenner, W., Malinowski, M. B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O. J., Tacke, F., Morkel, M. & Cramer, T., 07.2019, In: ONCOGENE. 38, 28, p. 5670-5685 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Diagnostic performance of the specific uptake size index for semi-quantitative analysis of I-123-FP-CIT SPECT: harmonized multi-center research setting versus typical clinical single-camera setting

    Buchert, R., Lange, C., Spehl, T. S., Apostolova, I., Frings, L., Jonsson, C., Meyer, P. T. & Hellwig, S., 07.05.2019, In: EJNMMI RES. 9, 1, p. 37

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Interobserver variability of image-derived arterial blood SUV in whole-body FDG PET

    Hofheinz, F., Maus, J., Zschaeck, S., Rogasch, J., Schramm, G., Oehme, L., Apostolova, I., Kotzerke, J. & den Hoff, J. V., 04.03.2019, In: EJNMMI RES. 9, 1, p. 23

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Clinical impact of “true whole-body” Ga-68-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities

    Stolzenbach, F., Maurer, T., Budäus, L., Steuber, T., Graefen, M., Sauer, M., Kobayashi, Y., Apostolova, I. & Berliner, C., 2019, In: NUKLEARMED-NUCL MED. 58, 02, p. P16

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Detection rate of Tc-99 m-PSMA I&S SPECT/CT in comparison to Ga-68-PSMA PET/CT in patients with biochemically recurrent prostate cancer planned for radioguided surgery

    Berliner, C., Sauer, M., Kobayashi, Y., Buchert, R., Mester, J., Maurer, T., Stolzenbach, F., Wester, HJ., Apostolova, I. & Bannas, P., 2019, In: NUKLEARMED-NUCL MED. 58, 02, p. P9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Feasibility of cardiac preparation protocol in the diagnostic of endocarditis with FDG-PET CT in clinical routine

    Berliner, C., Sauer, M., Buchert, R., Mester, J., Adam, G., Klutmann, S. & Apostolova, I., 2019, In: NUKLEARMED-NUCL MED. 58, 02, p. P118

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. The association of intra-therapeutic heterogeneity of somatostatin receptor expression with morphological treatment response in patients undergoing PRRT with [177Lu]-DOTATATE

    Wetz, C., Genseke, P., Apostolova, I., Furth, C., Ghazzawi, S., Rogasch, J. M. M., Schatka, I., Kreissl, M. C., Hofheinz, F., Grosser, O. S. & Amthauer, H., 2019, In: PLOS ONE. 14, 5, p. e0216781

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Vergleich von Tc-99 m-PSMA I&S SPECT/CT und Ga-68-PSMA PET/CT vor Gammasonden-gesteuerter Operation bei Prostatakarzinomrezidiv

    Stolzenbach, F., Sauer, M., Kobayashi, Y., Buchert, R., Mester, J., Maurer, T., Wester, H., Apostolova, I., Bannas, P. & Berliner, C., 2019, In: ROFO-FORTSCHR RONTG. 191, S 01, p. WISS 401.5

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. 2018
  44. Impact of plasma glucose level on the pattern of brain FDG uptake and the predictive power of FDG PET in mild cognitive impairment

    Apostolova, I., Lange, C., Suppa, P., Spies, L., Klutmann, S., Adam, G., Grothe, M. J., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 07.2018, In: EUR J NUCL MED MOL I. 45, 8, p. 1417-1422 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Magnetic resonance imaging-based hippocampus volume for prediction of dementia in mild cognitive impairment: Why does the measurement method matter so little?

    Buchert, R., Lange, C., Suppa, P., Apostolova, I., Spies, L., Teipel, S., Dubois, B., Hampel, H. & Grothe, M. J., 07.2018, In: ALZHEIMERS DEMENT. 14, 7, p. 976-978 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  46. Monitoring scanner calibration using the image-derived arterial blood SUV in whole-body FDG-PET

    Maus, J., Hofheinz, F., Apostolova, I., Kreissl, M. C., Kotzerke, J. & van den Hoff, J., 15.05.2018, In: EJNMMI RES. 8, 1, p. 38

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Hypermetabolism in the hippocampal formation of cognitively impaired patients indicates detrimental maladaptation

    Apostolova, I., Lange, C., Mäurer, A., Suppa, P., Spies, L., Grothe, M. J., Nierhaus, T., Fiebach, J. B., Steinhagen-Thiessen, E., Buchert, R. & Alzheimer’s Disease Neuroimaging Initiative, 05.2018, In: NEUROBIOL AGING. 65, p. 41-50 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. 2017
  49. Test-retest variability of lesion SUV and lesion SUR in (18)F-FDG PET: an analysis of data from two prospective multicenter trials

    Hofheinz, F., Apostolova, I., Oehme, L., Kotzerke, J. & van den Hoff, J., 11.2017, In: J NUCL MED. 58, 11, p. 1770-1775

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Utility of Follow-up Dopamine Transporter SPECT With 123I-FP-CIT in the Diagnostic Workup of Patients With Clinically Uncertain Parkinsonian Syndrome

    Apostolova, I., Taleb, D. S., Lipp, A., Galazky, I., Kupitz, D., Lange, C., Makowski, M. R., Brenner, W., Amthauer, H., Plotkin, M. & Buchert, R., 08.2017, In: CLIN NUCL MED. 42, 8, p. 589-594 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Predictive Value of Asphericity in Pretherapeutic [(111)In]DTPA-Octreotide SPECT/CT for Response to Peptide Receptor Radionuclide Therapy with [(177)Lu]DOTATATE

    Wetz, C., Apostolova, I., Steffen, I. G., Hofheinz, F., Furth, C., Kupitz, D., Ruf, J., Venerito, M., Klose, S. & Amthauer, H., 06.2017, In: MOL IMAGING BIOL. 19, 3, p. 437-445 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Detection of obstructive uropathy and assessment of differential renal function using two functional magnetic resonance urography tools. A comparison with diuretic renal scintigraphy in infants and children

    Genseke, P., Rogasch, J. M. M., Steffen, I. G., Neumann, G., Apostolova, I., Ruf, J., Rißmann, A., Wiemann, D., Liehr, U-B., Schostak, M., Amthauer, H. & Furth, C., 14.02.2017, In: NUKLEARMED-NUCL MED. 56, 1, p. 39-46 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Challenges in Screening and Recruitment for a Neuroimaging Study in Cognitively Impaired Geriatric Inpatients

    Apostolova, I., Lange, C., Roberts, A., Igel, H. J., Mäurer, A., Liese, S., Estrella, M., Prasad, V., Stechl, E., Lämmler, G., Steinhagen-Thiessen, E. & Buchert, R., 2017, In: J ALZHEIMERS DIS. 56, 1, p. 197-204 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Software-assisted dosimetry in peptide receptor radionuclide therapy with 177Lutetium-DOTATATE for various imaging scenarios

    Kupitz, D., Wetz, C., Wissel, H., Wedel, F., Apostolova, I., Wallbaum, T., Ricke, J., Amthauer, H. & Grosser, O. S., 2017, In: PLOS ONE. 12, 11, p. e0187570

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. 2016
  56. An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET

    Hofheinz, F., Bütof, R., Apostolova, I., Zöphel, K., Steffen, I. G., Amthauer, H., Kotzerke, J., Baumann, M. & van den Hoff, J., 12.2016, In: EJNMMI RES. 6, 1, p. 19

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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