Dr. PD ID: 34090
Guido Hermey
Publications
- 2023
Internally tagged Vps10p-Domain receptors reveal uptake of the neurotrophin BDNF
Klein, M., Failla, A. V. & Hermey, G., 10.2023, In: J BIOL CHEM. 299, 10, p. 105216Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Converging links between adult-onset neurodegenerative Alzheimer's disease and early life neurodegenerative neuronal ceroid lipofuscinosis?
Klein, M. & Hermey, G., 07.2023, In: NEURAL REGEN RES. 18, 7, p. 1463-1471 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
The Batten disease protein CLN3 is important for stress granules dynamics and translational activity
Relton, E. L., Roth, N. J., Yasa, S., Kaleem, A., Hermey, G., Minnis, C. J., Mole, S. E., Shelkovnikova, T., Lefrancois, S., McCormick, P. J. & Locker, N., 05.2023, In: J BIOL CHEM. 299, 5, p. 104649Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease
Scotto Rosato, A., Krogsaeter, E. K., Jaślan, D., Abrahamian, C., Montefusco, S., Soldati, C., Spix, B., Pizzo, M. T., Grieco, G., Böck, J., Wyatt, A., Wünkhaus, D., Passon, M., Stieglitz, M., Keller, M., Hermey, G., Gruber-Schoffnegger, D., Cotman, S., Johannes, L., Crusius, D., Wahl-Schott, C., Biel, M., Bracher, F., De Leonibus, E., Polishchuk, E., Medina, D. L., Paquet, D. & Grimm, C., 07.09.2022, In: EMBO MOL MED. 14, 9, e15377.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system
Klein, M., Kaleem, A., Oetjen, S., Wünkhaus, D., Binkle, L., Schilling, S., Gjorgjieva, M., Scholz, R., Gruber-Schoffnegger, D., Storch, S., Kins, S., Drewes, G., Hoffmeister-Ullerich, S., Kuhl, D. & Hermey, G., 09.2022, In: AUTOPHAGY. 18, 9, p. 2068-2085 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The adaptor protein PICK1 targets the sorting receptor SorLA
Binkle-Ladisch, L., Klein, M., Borgmeyer, U., Kuhl, D. & Hermey, G., 19.02.2022, In: MOL BRAIN. 15, 1, p. 18 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deciphering the transcriptomic signature of synaptic activity
Hermey, G., 01.2022, In: NEURAL REGEN RES. 17, 1, p. 82-84 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2020
Neuronal activity regulates alternative exon usage
Denkena, J., Zaisser, A., Merz, B., Klinger, B., Kuhl, D., Blüthgen, N. & Hermey, G., 10.11.2020, In: MOL BRAIN. 13, 1, p. 148Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CLN3 regulates endosomal function by modulating Rab7A effector interactions
Yasa, S., Modica, G., Sauvageau, E., Kaleem, A., Hermey, G. & Lefrancois, S., 16.03.2020, In: J CELL SCI. 133, 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice
Hermey, G., Hoffmeister-Ullerich, S. A., Merz, B., Groß, D., Kuhl, D. & Kins, S., 27.08.2019, In: BIOL CHEM. 400, 9, p. 1181-1189 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
SORCS1 and SORCS3 control energy balance and orexigenic peptide production
Subkhangulova, A., Malik, A. R., Hermey, G., Popp, O., Dittmar, G., Rathjen, T., Poy, M. N., Stumpf, A., Beed, P. S., Schmitz, D., Breiderhoff, T. & Willnow, T. E., 04.2018, In: EMBO REP. 19, 4, p. e44810Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA
Eggert, S., Gonzalez, A. C., Thomas, C., Schilling, S., Schwarz, S. M., Tischer, C., Adam, V., Strecker, P., Schmidt, V., Willnow, T. E., Hermey, G., Pietrzik, C. U., Koo, E. H. & Kins, S., 01.2018, In: CELL MOL LIFE SCI. 75, 2, p. 301-322 22 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin
Eggert, S., Thomas, C., Kins, S. & Hermey, G., 2018, In: MOL NEUROBIOL. 55, 7, p. 5809-5829Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2017
Neuronal activity-regulated alternative mRNA splicing
Hermey, G., Blüthgen, N. & Kuhl, D., 10.2017, In: INT J BIOCHEM CELL B. 91, Pt B, p. 184-193 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo
Blüthgen, N., van Bentum, M., Merz, B., Kuhl, D. & Hermey, G., 28.03.2017, In: SCI REP-UK. 7, 45101, p. 1-14Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Revisiting the neuronal localization and trafficking of CLN3 in juvenile neuronal ceroid lipofuscinosis
Oetjen, S., Kuhl, D. & Hermey, G., 01.11.2016, In: J NEUROCHEM. 139, 3, p. 456-470 doi: 10.1111/jnc.13744.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Intracellular sorting pathways of the amyloid precursor protein provide novel neuroprotective strategies
Hermey, G., 30.11.2015, In: NEURAL REGEN RES. 10, 11, p. 1727-1728 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport
Hermey, G., Schmidt, N., Bluhm, B., Mensching, D., Ostermann, K., Rupp, C., Kuhl, D. & Kins, S., 10.2015, In: J NEUROCHEM. 135, 1, p. 60-75 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Spatiotemporal expression analysis of the growth factor receptor SorCS3
Oetjen, S., Mahlke, C., Hermans-Borgmeyer, I. & Hermey, G., 15.10.2014, In: J COMP NEUROL. 522, 15, p. 3386-402 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia
Glerup, S., Olsen, D., Vaegter, C. B., Gustafsen, C., Sjoegaard, S. S., Hermey, G., Kjolby, M., Molgaard, S., Ulrichsen, M., Boggild, S., Skeldal, S., Fjorback, A. N., Nyengaard, J. R., Jacobsen, J., Bender, D., Bjarkam, C. R., Sørensen, E. S., Füchtbauer, E-M., Eichele, G., Madsen, P., Willnow, T. E., Petersen, C. M. & Nykjaer, A., 04.06.2014, In: NEURON. 82, 5, p. 1074-87 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human sorCS1 binds sortilin and hampers its cellular functions
Larsen, J. V., Hermey, G., Sørensen, E. S., Prabakaran, T., Christensen, E. I., Gliemann, J., Madsen, P. & Petersen, C. M., 15.01.2014, In: BIOCHEM J. 457, 2, p. 277-88 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Genome-wide profiling of the activity-dependent hippocampal transcriptome
Hermey, G., Mahlke, C., Gutzmann, J. J., Schreiber, J., Blüthgen, N. & Kuhl, F-D., 01.01.2013, In: PLOS ONE. 8, 10, p. e76903Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Targeting amyloid precursor protein.
Hermey, G., 2011, In: ANN NEUROL. 69, 1, p. 8-10 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
The Vps10p-domain receptor family.
Hermey, G., 2009, In: CELL MOL LIFE SCI. 66, 16, p. 2677-2689 16.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Different motifs regulate trafficking of SorCS1 isoforms.
Nielsen, M. S., Keat, S. J., Hamati, J. W., Madsen, P., Gutzmann, J. J., Engelsberg, A., Pedersen, K. M., Gustafsen, C., Nykjaer, A., Gliemann, J., Hermans-Borgmeyer, I., Kuhl, D., Petersen, C. M. & Hermey, G., 2008, In: TRAFFIC. 9, 6, p. 980-994 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.
Nielsen, M. S., Gustafsen, C., Madsen, P., Nyengaard, J. R., Hermey, G., Bakke, O., Mari, M., Schu, P., Pohlmann, R., Dennes, A. & Petersen, C. M., 2007, In: MOL CELL BIOL. 27, 19, p. 6842-6851 19.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members.
Hermey, G., Sjøgaard, S. S., Petersen, C. M., Nykjaer, A. & Gliemann, J., 2006, In: BIOCHEM J. 395, 2, p. 285-293 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
Functional organization of the sortilin Vps10p domain.
Westergaard, U. B., Sørensen, E. S., Hermey, G., Nielsen, M. S., Nykjaer, A., Kirkegaard, K., Jacobsen, C., Gliemann, J., Madsen, P. & Petersen, C. M., 2004, In: J BIOL CHEM. 279, 48, p. 50221-50229 48.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.
Gliemann, J., Hermey, G., Nykjaer, A., Petersen, C. M., Jacobsen, C. & Andreasen, P. A., 2004, In: BIOCHEM J. 381, 1, p. 203-212 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The three sorCS genes are differentially expressed and regulated by synaptic activity.
Hermey, G., Plath, N., Hübner, C. A., Kuhl, D., Schaller, H. C. & Hermans-Borgmeyer, I., 2004, In: J NEUROCHEM. 88, 6, p. 1470-1476 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells.
Hermey, G., Keat, S. J., Madsen, P., Jacobsen, C., Petersen, C. M. & Gliemann, J., 2003, In: J BIOL CHEM. 278, 9, p. 7390-7396 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain.
Rezgaoui, M., Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 2001, In: MECH DEVELOP. 100, 2, p. 335-338 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SorCS1, a member of the novel sorting receptor family, is localized in somata and dendrites of neurons throughout the murine brain.
Hermey, G., Riedel, I. B., Rezgaoui, M., Westergaard, U. B., Schaller, C. & Hermans-Borgmeyer, I., 2001, In: NEUROSCI LETT. 313, 1-2, p. 83-87 1-2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transient expression of SorCS in developing telencephalic and mesencephalic structures of the mouse.
Hermey, G., Schaller, H. C. & Hermans-Borgmeyer, I., 2001, In: NEUROREPORT. 12, 1, p. 29-32 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
Alternative splicing of murine SorCS leads to two forms of the receptor that differ completely in their cytoplasmic tails.
Hermey, G. & Schaller, H. C., 2000, In: BBA-GENE STRUCT EXPR. 1491, 1-3, p. 350-354 1-3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1999
Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development.
Hermans-Borgmeyer, I., Hermey, G., Nykjaer, A. & Schaller, C., 1999, In: MOL BRAIN RES. 65, 2, p. 216-219 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification and characterization of SorCS, a third member of a novel receptor family.
Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 1999, In: BIOCHEM BIOPH RES CO. 266, 2, p. 347-351 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of a novel seven-transmembrane receptor with homology to glycoprotein receptors and its expression in the adult and developing mouse.
Hermey, G., Methner, A., Schaller, H. C. & Hermans-Borgmeyer, I., 1999, In: BIOCHEM BIOPH RES CO. 254, 1, p. 273-279 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1997
A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development.
Methner, A., Hermey, G., Schinke, B. & Hermans-Borgmeyer, I., 1997, In: BIOCHEM BIOPH RES CO. 233, 2, p. 336-342 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review