Research ExplorerScientific StaffEva Tolosa Publications

ID: 37028

Eva Tolosa

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Publications

  1. 2016

  2. IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis

    Thom, V., Schmidt, S., Gelderblom, M., Hackbusch, R., Kolster, M., Schuster, S., Thomalla, G., Keminer, O., Pleß, O., Bernreuther, C., Glatzel, M., Wegscheider, K., Gerloff, C., Magnus, T. & Tolosa, E., 21.03.2016, In: NEUROL-NEUROIMMUNOL. 3, 2, p. e214

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Fetal thymus size in human pregnancies reveals inverse association with regulatory T cell frequencies in cord blood

    Diemert, A., Hartwig, I., Pagenkemper, M., Mehnert, R., Hansen, G., Tolosa, E., Hecher, K. & Arck, P., 02.2016, In: J REPROD IMMUNOL. 113, p. 76-82 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Interleukin 17, Produced by γδ T Cells, Contributes to Hepatic Inflammation in a Mouse Model of Biliary Atresia and Is Increased in Livers of Patients

    Klemann, C., Schröder, A., Dreier, A., Möhn, N., Dippel, S., Winterberg, T., Wilde, A., Yu, Y., Thorenz, A., Gueler, F., Jörns, A., Tolosa, E., Leonhardt, J., Haas, J. D., Prinz, I., Vieten, G., Petersen, C. & Kuebler, J. F., 01.2016, In: GASTROENTEROLOGY. 150, 1, p. 229-241.e5

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. 2015

  6. Babies Galore; or recent findings and future perspectives of pregnancy cohorts with a focus on immunity

    Hartwig, I., Diemert, A., Tolosa, E., Hecher, K. & Arck, P., 01.04.2015, In: J REPROD IMMUNOL. 108, p. 6-11 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. The expression of CD39 on regulatory T cells is genetically driven and further upregulated at sites of inflammation

    Rissiek, A., Baumann, I., Cuapio, A., Mautner, A., Kolster, M., Arck, P. C., Dodge-Khatami, A., Mittrücker, H-W., Nolte, F., Haag, F. & Tolosa, E., 01.04.2015, In: J AUTOIMMUN. 58, p. 12-20 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Mannose 6 phosphorylation of lysosomal enzymes controls B cell functions

    Otomo, T., Schweizer, M., Kollmann, K., Schumacher, V., Muschol, N., Tolosa, E., Mittrücker, H-W. & Braulke, T., 19.01.2015, In: J CELL BIOL. 208, 2, p. 171-80 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2014

  10. Multidimensional scaling analysis identifies pathological and prognostically relevant profiles of circulating T-cells in chronic lymphocytic leukemia

    Rissiek, A., Schulze, C., Bacher, U., Schieferdecker, A., Thiele, B., Jacholkowski, A., Flammiger, A., Horn, C., Haag, F., Tiegs, G., Zirlik, K., Trepel, M., Tolosa, E. & Binder, M., 11.04.2014, In: INT J CANCER. 135, 10, p. 2370-2379

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. 2013

  12. Effect of prenatal steroid treatment on the developing immune system

    Diepenbruck, I., Much, C. C., Krumbholz, A., Kolster, M., Thieme, R., Thieme, D., Diepenbruck, S., Solano, M. E., Arck, P. C. & Tolosa, E., 01.11.2013, In: J MOL MED. 91, 11, p. 1293-302 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Exploring the MHC-peptide matrix of central tolerance in the human thymus

    Adamopoulou, E., Tenzer, S., Hillen, N., Klug, P., Rota, I. A., Tietz, S., Gebhardt, M., Stevanovic, S., Schild, H., Tolosa, E., Melms, A. & Stoeckle, C., 01.01.2013, In: NAT COMMUN. 4, p. 2039

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Fine mapping and functional analysis of the multiple sclerosis risk gene CD6

    Swaminathan, B., Cuapio, A., Alloza, I., Matesanz, F., Alcina, A., García-Barcina, M., Fedetz, M., Fernández, O., Lucas, M., Orpez, T., Pinto-Medel, M. J., Otaegui, D., Olascoaga, J., Urcelay, E., Ortiz, M. A., Arroyo, R., Oksenberg, J. R., Antigüedad, A., Tolosa, E. & Vandenbroeck, K., 01.01.2013, In: PLOS ONE. 8, 4, p. e62376

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Isolation of myeloid dendritic cells and epithelial cells from human thymus

    Stoeckle, C., Rota, I. A., Tolosa, E., Haller, C., Melms, A. & Adamopoulou, E., 01.01.2013, In: JOVE-J VIS EXP. 79, p. e50951

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Relapsing cerebral aspergilloma associated with pregnancy.

    Krützelmann, A. C., Sobottka, I., Fiehler, J., Tolosa, E., Gerloff, C. & Rosenkranz, M., 2013, In: CLIN NEUROL NEUROSUR. 115, 7, p. 1154-1156 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2012

  18. Cathepsin S dominates autoantigen processing in human thymic dendritic cells.

    Stoeckle, C., Quecke, P., Rückrich, T., Burster, T., Reich, M., Weber, E., Kalbacher, H., Driessen, C., Melms, A. & Tolosa, E., 2012, In: J AUTOIMMUN. 38, 4, p. 332-343 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.

    Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.

    Gelderblom, M., Leypoldt, F., Lewerenz, J., Birkenmayer, G., Orozco, D., Ludewig, P., Thundyil, J., Arumugam, T. V., Gerloff, C., Tolosa, E., Maher, P. & Magnus, T., 2012, In: J CEREBR BLOOD F MET. 32, 5, p. 835-843 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. 2010

  22. Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice

    Sevenich, L., Hagemann, S., Stoeckle, C., Tolosa, E., Peters, C. & Reinheckel, T., 01.11.2010, In: BIOCHIMIE. 92, 11, p. 1674-80 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. 2009

  24. Cathepsin G is differentially expressed in primary human antigen-presenting cells.

    Stoeckle, C., Sommandas, V., Adamopoulou, E., Belisle, K., Schiekofer, S., Melms, A., Weber, E., Driessen, C., Fleischer, B., Tolosa, E. & Burster, T., 2009, In: CELL IMMUNOL. 255, 1-2, p. 41-45 1-2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs.

    Stoeckle, C., Gouttefangeas, C., Hammer, M., Weber, E., Melms, A. & Tolosa, E., 2009, In: EXP HEMATOL. 37, 2, p. 266-275 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Detection of aberrant transcription of major histocompatibility complex class II antigen presentation genes in chronic lymphocytic leukaemia identifies HLA-DOA mRNA as a prognostic factor for survival.

    Souwer, U., Yuri, U., Chamuleau, U., Martine, E. D., Loosdrecht, V. D., Arjan, A., Tolosa, E., Eva, U., Jorritsma, U., Tineke, U., Muris, U., Jettie, J. F., Poppel, D., Marion, J., Snel, U., Sander, N., Corput, V. D., Lisette, U., Ossenkoppele, U., Gert, J., Meijer, U., Chris, J. L. M., Neefjes, U., Jacques, J. & van Ham, M., 2009, In: BRIT J HAEMATOL. 145, 3, p. 334-343 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Phenotypical Characterization of Human Th17 Cells Unambiguously Identified by Surface IL-17A Expression

    Brucklacher-Waldert, V., Steinbach, K., Lioznov, M., Kolster, M., Hölscher, C. & Tolosa, E., 2009, In: J IMMUNOL. 183, p. 5494-5501

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.

    Gelderblom, M., Leypoldt, F., Steinbach, K., Behrens, D., Choe, C-U., Siler, D. A., Arumugam, T. V., Orthey, E., Gerloff, C., Tolosa, E. & Magnus, T., 2009, In: STROKE. 40, 5, p. 1849-1857 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. 2008

  30. Natural killer cells are required for accelerated type 1 diabetes driven by interferon-beta

    Alba, A., Planas, R., Clemente, X., Carrillo, J., Ampudia, R., Puertas, M-C., Pastor, X., Tolosa, E., Pujol-Borrell, R., Verdaguer, J. & Vives-Pi, M., 01.03.2008, In: CLIN EXP IMMUNOL. 151, 3, p. 467-75 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels.

    Kessler, T., Reich, M., Jahn, G., Tolosa, E., Beck, A., Kalbacher, H., Overkleeft, H., Schempp, S. & Driessen, C., 2008, In: J GEN VIROL. 89, Pt 10, p. 2427-2436 Pt 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. 2007

  33. Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro

    Burster, T., Beck, A., Poeschel, S., Øren, A., Baechle, D., Reich, M., Roetzschke, O., Falk, K., Boehm, B. O., Youssef, S., Kalbacher, H., Overkleeft, H., Tolosa, E. & Driessen, C., 01.05.2007, In: IMMUNOLOGY. 121, 1, p. 82-93 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients

    Feger, U., Luther, C., Poeschel, S., Melms, A., Tolosa, E. & Wiendl, H., 01.03.2007, In: CLIN EXP IMMUNOL. 147, 3, p. 412-8 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration.

    Rosenkranz, D., Weyer, S., Tolosa, E., Gaenslen, A., Berg, D., Leyhe, T., Gasser, T. & Stoltze, L., 2007, In: J NEUROIMMUNOL. 188, 1-2, p. 117-127 1-2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation.

    Feger, U., Tolosa, E., Huang, Y-H., Waschbisch, A., Biedermann, T., Melms, A. & Wiendl, H., 2007, In: BLOOD. 110, 2, p. 568-577 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Human CD4+ T cells displaying viral epitopes elicit a functional virus-specific memory CD8+ T cell response.

    Adamopoulou, E., Diekmann, J., Tolosa, E., Kuntz, G., Einsele, H., Rammensee, H-G. & Topp, M. S., 2007, In: J IMMUNOL. 178, 9, p. 5465-5472 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.

    Viken, M. K., Sollid, H. D., Joner, G., Dahl-Jørgensen, K., Rønningen, K. S., Undlien, D. E., Flatø, B., Selvaag, A. M., Førre, Ø., Kvien, T. K., Thorsby, E., Melms, A., Tolosa, E. & Lie, B. A., 2007, In: HUM IMMUNOL. 68, 9, p. 748-755 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. 2006

  40. Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules

    Drumea-Mirancea, M., Wessels, J. T., Müller, C. A., Essl, M., Eble, J. A., Tolosa, E., Koch, M., Reinhardt, D. P., Sixt, M., Sorokin, L., Stierhof, Y-D., Schwarz, H. & Klein, G., 01.04.2006, In: J CELL SCI. 119, Pt 7, p. 1396-405 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Thymus and myasthenia gravis: antigen processing in the human thymus and the consequences for the generation of autoreactive T cells

    Melms, A., Luther, C., Stoeckle, C., Pöschel, S., Schroth, P., Varga, M., Wienhold, W. & Tolosa, E., 01.01.2006, In: ACTA NEUROL SCAND. 113, s183, p. 12-13 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  42. 2005

  43. Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells

    Burster, T., Beck, A., Tolosa, E., Schnorrer, P., Weissert, R., Reich, M., Kraus, M., Kalbacher, H., Häring, H-U., Weber, E., Overkleeft, H. & Driessen, C., 01.11.2005, In: J IMMUNOL. 175, 9, p. 5940-9 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Decreased frequency of intrathymic regulatory T cells in patients with myasthenia-associated thymoma

    Luther, C., Poeschel, S., Varga, M., Melms, A. & Tolosa, E., 01.07.2005, In: J NEUROIMMUNOL. 164, 1-2, p. 124-8 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Alternatively spliced transcripts of the thymus-specific protease PRSS16 are differentially expressed in human thymus

    Luther, C., Wienhold, W., Oehlmann, R., Heinemann, M. K., Melms, A. & Tolosa, E., 01.02.2005, In: GENES IMMUN. 6, 1, p. 1-7 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. 2004

  47. Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes

    Burster, T., Beck, A., Tolosa, E., Marin-Esteban, V., Rötzschke, O., Falk, K., Lautwein, A., Reich, M., Brandenburg, J., Schwarz, G., Wiendl, H., Melms, A., Lehmann, R., Stevanovic, S., Kalbacher, H. & Driessen, C., 01.05.2004, In: J IMMUNOL. 172, 9, p. 5495-503 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus

    Bruno, R., Sabater, L., Tolosa, E., Sospedra, M., Ferrer-Francesch, X., Coll, J., Foz, M., Melms, A. & Pujol-Borrell, R., 01.04.2004, In: J NEUROIMMUNOL. 149, 1-2, p. 147-59 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. 2003

  50. Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo

    Schreiner, B., Wischhusen, J., Mitsdoerffer, M., Schneider, D., Bornemann, A., Melms, A., Tolosa, E., Weller, M. & Wiendl, H., 01.12.2003, In: GLIA. 44, 3, p. 296-301 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

    Tolosa, E., Li, W., Yasuda, Y., Wienhold, W., Denzin, L. K., Lautwein, A., Driessen, C., Schnorrer, P., Weber, E., Stevanovic, S., Kurek, R., Melms, A. & Bromme, D., 01.08.2003, In: J CLIN INVEST. 112, 4, p. 517-26 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis

    Wiendl, H., Neuhaus, O., Mehling, M., Wintterle, S., Schreiner, B., Mitsdoerffer, M., Wienhold, W., Weissert, R., Wessels, J., Hartung, H-P., Weller, M., Tolosa, E. & Melms, A., 01.07.2003, In: J NEUROIMMUNOL. 140, 1-2, p. 177-87 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies

    Wiendl, H., Lautwein, A., Mitsdörffer, M., Krause, S., Erfurth, S., Wienhold, W., Morgalla, M., Weber, E., Overkleeft, H. S., Lochmüller, H., Melms, A., Tolosa, E. & Driessen, C., 01.05.2003, In: J NEUROIMMUNOL. 138, 1-2, p. 132-43 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. 1999

  55. Genomic instability in Gadd45a-deficient mice

    Hollander, M. C., Sheikh, M. S., Bulavin, D. V., Lundgren, K., Augeri-Henmueller, L., Shehee, R., Molinaro, T. A., Kim, K. E., Tolosa, E., Ashwell, J. D., Rosenberg, M. P., Zhan, Q., Fernández-Salguero, P. M., Morgan, W. F., Deng, C. X. & Fornace, A. J., 01.10.1999, In: NAT GENET. 23, 2, p. 176-84 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+)CD8(+) thymocytes

    King, L. B., Tolosa, E., Lenczowski, J. M., Lu, F., Lind, E. F., Hunziker, R., Petrie, H. T. & Ashwell, J. D., 01.08.1999, In: INT IMMUNOL. 11, 8, p. 1203-16 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  57. Thymus-derived glucocorticoids and the regulation of antigen-specific T-cell development

    Tolosa, E. & Ashwell, J. D., 1999, In: NEUROIMMUNOMODULAT. 6, 1-2, p. 90-6 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. 1998

  59. Triptolide induces apoptotic death of T lymphocyte

    Yang, Y., Liu, Z., Tolosa, E., Yang, J. & Li, L., 01.08.1998, In: IMMUNOPHARMACOLOGY. 40, 2, p. 139-49 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  60. Thymocyte glucocorticoid resistance alters positive selection and inhibits autoimmunity and lymphoproliferative disease in MRL-lpr/lpr mice

    Tolosa, E., King, L. B. & Ashwell, J. D., 01.01.1998, In: IMMUNITY. 8, 1, p. 67-76 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  61. 1997

  62. Hyperexpression of transporter in antigen processing-1 (TAP-1) in thyroid glands affected by autoimmunity: a contributing factor to the breach of tolerance to thyroid antigens?

    Sospedra, M., Tolosa, E., Armengol, P., Ashhab, Y., Urlinger, S., Lucas-Martin, A., Foz-Sala, M., Jaraquemada, D. & Pujol-Borrell, R., 01.07.1997, In: CLIN EXP IMMUNOL. 109, 1, p. 98-106 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  63. 1996

  64. A fluorogenic assay of endogenous phosphatase for assessment of cell adhesion

    Tolosa, E. & Shaw, S., 10.06.1996, In: J IMMUNOL METHODS. 192, 1-2, p. 165-72 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  65. 1995

  66. Hyperinducibility of HLA class II expression of thyroid follicular cells from Graves' disease. A primary defect?

    Sospedra, M., Obiols, G., Babi, L. F., Tolosa, E., Vargas, F., Roura-Mir, C., Lucas-Martin, A., Ercilla, G. & Pujol-Borrell, R., 15.04.1995, In: J IMMUNOL. 154, 8, p. 4213-22 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  67. 1994

  68. Characterization of neural cell adhesion molecule (NCAM) expression in thyroid follicular cells: induction by cytokines and over-expression in autoimmune glands

    Vargas, F., Tolosa, E., Sospedra, M., Catálfamo, M., Lucas-Martín, A., Obiols, G. & Pujol-Borrell, R., 01.12.1994, In: CLIN EXP IMMUNOL. 98, 3, p. 478-88 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  69. 1993

  70. Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats

    Franch, A., Castellote, C., Pelegrí, C., Tolosa, E. & Castell, M., 01.09.1993, In: ANN HEMATOL. 67, 3, p. 115-8 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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