Dr.med. ID: 5810778

Dominik Sebastian Nörz

graph of relations

Publications

  1. 2024
  2. Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system

    Giersch, K., Tanida, K., Both, A., Nörz, D., Heim, D., Rohde, H., Aepfelbacher, M. & Lütgehetmann, M., 12.02.2024, In: SCI REP-UK. 14, 1, p. 3523

    Research output: SCORING: Contribution to journalSCORING: Journal articleTransferpeer-review

  3. Immunity against measles, mumps, rubella, and varicella among homeless individuals in Germany - A nationwide multi-center cross-sectional study

    Graf, W., Bertram, F., Dost, K. M., Brennecke, A., Kowalski, V., van Rüth, V., Nörz, D. S., Wulff, B., Ondruschka, B., Püschel, K., Pfefferle, S., Lütgehetmann, M. & Heinrich, F., 2024, In: FRONT PUBLIC HEALTH. 12, p. 1375151 1375151.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. 2023
  5. Comparison of four commercial EBV DNA quantitative tests to a new test at an early stage of development

    Stelzl, E., Kessler, H. H., Parulekar, A. D., Bier, C., Nörz, D., Schneider, T., Kumar, S., Simon, C. O. & Lütgehetmann, M., 04.2023, In: J CLIN VIROL. 161, 105400.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany

    Heinrich, F., Huter, T., Mertens, S., Lange, P., Vering, J., Heinemann, A., Nörz, D. S., Hoffmann, A., Aepfelbacher, M., Ondruschka, B., Krasemann, S. & Lütgehetmann, M., 03.2023, In: EMERG INFECT DIS. 29, 3, p. 652-656 5 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  7. Long-Term Antibody Response to SARS-CoV-2 in Children

    Dunay, G. A., Barroso, M., Woidy, M., Danecka, M. K., Engels, G., Hermann, K., Neumann, F. S., Paul, K., Beime, J., Escherich, G., Fehse, K., Grinstein, L., Haniel, F., Haupt, L. J., Hecher, L., Kehl, T., Kemen, C., Kemper, M. J., Kobbe, R., Kohl, A., Klokow, T., Nörz, D., Olfe, J., Schlenker, F., Schmiesing, J., Schrum, J., Sibbertsen, F., Stock, P., Tiede, S., Vettorazzi, E., Zazara, D. E., Zapf, A., Lütgehetmann, M., Oh, J., Mir, T. S., Muntau, A. C., Gersting, S. W. & C19.CHILD Study Group, 01.2023, In: J CLIN IMMUNOL. 43, 1, p. 46-56 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. 2022
  9. Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don't Trust Ct Value

    Knobloch, J. K., Pfefferle, S., Lütgehetmann, M., Nörz, D., Klupp, E. M., Belmar Campos, C. E., Kluge, S., Aepfelbacher, M., Knobling, B. & Franke, G., 19.12.2022, In: INT J ENV RES PUB HE. 19, 24, 17074.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Screening for Monkeypox Infection in Asymptomatic High-Risk-Behaviour Men Having Sex with Men (MSM)

    Pestel, J., Matthews, H., Schmiedel, S., Hüfner, A., Jordan, S., Scheiter, R. L., Lütgehetmann, M., Nörz, D. & Degen, O., 17.10.2022, In: INFECT DIS REP. 14, 5, p. 794-797 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus

    Nörz, D., Brehm, T. T., Tang, H. T., Grewe, I., Hermanussen, L., Matthews, H., Pestel, J., Degen, O., Günther, T., Grundhoff, A., Fischer, N., Addo, M. M., Jordan, S., Hertling, S., Unger, S., Schäfer, G., Schewe, K., Hoffmann, C., Aepfelbacher, M., Pfefferle, S., Schulze Zur Wiesch, J., Schmiedel, S. & Lütgehetmann, M., 10.2022, In: J CLIN VIROL. 155, 105254.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants

    Brehm, T. T., Pfefferle, S., von Possel, R., Karolyi, M., Zoufaly, A., Wichmann, D., Kobbe, R., Emmerich, P., Nörz, D., Aepfelbacher, M., Schulze Zur Wiesch, J., Addo, M. M., Schmiedel, S. & Lütgehetmann, M., 10.2022, In: J MED VIROL. 94, 10, p. 5038-5043 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort study

    Olearo, F., Radmanesh, L-S., Felber, N., von Possel, R., Emmerich, P., Pekarek, N., Pfefferle, S., Nörz, D., Hansen, G., Diemert, A., Aepfelbacher, M., Hecher, K., Lütgehetmann, M., Arck, P. C. & Tallarek, A-C., 09.2022, In: J REPROD IMMUNOL. 153, 103685.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Rapid Adaptation of Established High-Throughput Molecular Testing Infrastructure for Monkeypox Virus Detection

    Nörz, D., Tang, H. T., Emmerich, P., Giersch, K., Fischer, N., Schmiedel, S., Addo, M. M., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 09.2022, In: EMERG INFECT DIS. 28, 9, p. 1765-1769 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. New Safety Aspects in Corneal Donation-Studies on SARS-CoV-2-Positive Corneal Donors

    Wille, D., Heinzelmann, J., Kehlen, A., Lütgehetmann, M., Nörz, D. S., Siebolts, U., Mueller, A., Karrasch, M., Hofmann, N., Viestenz, A., Börgel, M., Kuhn, F. & Viestenz, A., 09.06.2022, In: J CLIN MED. 11, 12, 3312.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. The Prevalence of Early‐ and Late‐Onset Bacterial, Viral and Fungal Respiratory Superinfections in Invasively Ventilated COVID‐19 Patients.

    Paparoupa, M., Aldemyati, R., Roggenkamp, H., Berinson, B., Nörz, D., Olearo, F., Kluge, S., Roedl, K., Heer, G. & Wichmann, D., 05.2022, In: J MED VIROL. 94, 5, p. 1920-1925 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants

    Nörz, D., Grunwald, M., Tang, H. T., Weinschenk, C., Günther, T., Robitaille, A., Giersch, K., Fischer, N., Grundhoff, A., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 15.03.2022, In: VIRUSES-BASEL. 14, 3, 608.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany

    Nakel, J., Robitaille, A., Günther, T., Rosenau, L., Czech-Sioli, M., Plenge-Bönig, A., Bühler, S., Wille, A., Jakubowski, E., Pruskil, S., Wahlen, M., Indenbirken, D., Nörz, D., Lütgehetmann, M., Aepfelbacher, M., Grundhoff, A., Grolle, B. & Fischer, N., 03.2022, In: INT J HYG ENVIR HEAL. 240, 113928.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant

    Heinrich, F., Romich, C., Zimmermann, T., Kniep, I., Fitzek, A., Steurer, S., Glatzel, M., Nörz, D., Günther, T., Czech-Sioli, M., Fischer, N., Grundhoff, A., Lütgehetmann, M. & Ondruschka, B., 01.2022, In: INT J LEGAL MED. 136, 1, p. 193-202 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths

    Heinrich, F., Schröder, A. S., Gerberding, A-L., Gerling, M., Langenwalder, F., Lange, P., Heinemann, A., Bibiza-Freiwald, E., Nörz, D. S., Aepfelbacher, M., Pfefferle, S., Ondruschka, B. & Lütgehetmann, M., 01.2022, In: EMERG INFECT DIS. 28, 1, p. 244-247 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  21. 2021
  22. Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system

    Pflüger, L. S., Nörz, D., Volz, T., Giersch, K., Giese, A., Goldmann, N., Glebe, D., Bockmann, J-H., Pfefferle, S., Dandri, M., Schulze Zur Wiesch, J. & Lütgehetmann, M., 12.2021, In: JHEP REP. 3, 6, 100356.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Multicenter Evaluation of a Fully Automated High-Throughput SARS-CoV-2 Antigen Immunoassay

    Nörz, D., Olearo, F., Perisic, S., Bauer, M. F., Riester, E., Schneider, T., Schönfeld, K., Laengin, T. & Lütgehetmann, M., 12.2021, In: INFECT DIS THER. 10, 4, p. 2371-2379 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients

    Heinrich, F., Nentwich, M. F., Bibiza-Freiwald, E., Nörz, D., Roedl, K., Christner, M., Hoffmann, A., Olearo, F., Kluge, S., Aepfelbacher, M., Wichmann, D., Lütgehetmann, M. & Pfefferle, S., 11.2021, In: OPEN FORUM INFECT DI. 8, 11, ofab509.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection

    Nörz, D., Grunwald, M., Tang, H. T., Olearo, F., Günther, T., Robitaille, A., Fischer, N., Grundhoff, A., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 01.10.2021, In: DIAGNOSTICS. 11, 10, 1818.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay

    Nörz, D., Pfefferle, S., Grunwald, M., Fischer, N., Aepfelbacher, M. & Lütgehetmann, M., 06.2021, In: J MOL DIAGN. 23, 6, p. 777-778 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  27. Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Drug Screening

    Nörz, D., Mullins, C. S., Smit, D. J., Linnebacher, M., Hagel, G., Mirdogan, A., Siekiera, J., Ehm, P., Izbicki, J. R., Block, A., Thastrup, O. & Jücker, M., 05.2021, In: ANTICANCER RES. 41, 5, p. 2257-2275 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies

    Brehm, T. T., Pfefferle, S., von Possel, R., Kobbe, R., Nörz, D., Schmiedel, S., Grundhoff, A., Olearo, F., Emmerich, P., Robitaille, A., Günther, T., Braun, P., Andersen, G., Knobloch, J. K., Addo, M. M., Lohse, A. W., Aepfelbacher, M., Fischer, N., Schulze Zur Wiesch, J. & Lütgehetmann, M., 12.04.2021, In: VIRUSES-BASEL. 13, 4, 661.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearch

  29. Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19

    Casagrande, M., Fitzek, A., Spitzer, M. S., Püschel, K., Glatzel, M., Krasemann, S., Nörz, D., Lütgehetmann, M., Pfefferle, S. & Schultheiss, M., 01.04.2021, In: JAMA OPHTHALMOL. 139, 4, p. 383-388 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Clinical evaluation of a laboratory-developed quantitative BK virus-PCR assay using the cobas® omni Utility Channel

    Fritzsche, A., Berneking, L., Nörz, D., Reucher, S., Fischer, N., Roggenkamp, H., Aepfelbacher, M., Rohde, H., Pfefferle, S. & Lütgehetmann, M., 04.2021, In: J VIROL METHODS. 290, p. 114093

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19

    Roedl, K., Heidenreich, S., Pfefferle, S., Jarczak, D., Urbanowicz, T. T., Nörz, D., Aepfelbacher, M., Kröger, N., Kluge, S., Lütgehetmann, M., Christopeit, M. & Wichmann, D., 15.01.2021, In: AM J RESP CRIT CARE. 203, 2, p. 242-245 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  32. SARS Coronavirus-2 variant tracing within the first Coronavirus Disease 19 clusters in northern Germany

    Pfefferle, S., Günther, T., Kobbe, R., Czech-Sioli, M., Nörz, D., Santer, R., Oh, J., Kluge, S., Oestereich, L., Peldschus, K., Indenbirken, D., Huang, J., Grundhoff, A., Aepfelbacher, M., Knobloch, J. K., Lütgehetmann, M. & Fischer, N., 01.2021, In: CLIN MICROBIOL INFEC. 27, 1, p. 130.e5-130.e8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Low incidence of COVID-19 in a prospective cohort of patients with liver cirrhosis and hepatocellular carcinoma treated at a tertiary medical center during the 2020 pandemic

    Fründt, T., Kuballa, L., Lütgehetman, M., Nörz, D., Arend, H., Brehm, T. T., Schulze Zur Wiesch, J., Horvatits, T., Horvatits, K., Huber, S., Wege, H. & Kluwe, J., 2021, In: PLOS ONE. 16, 12, p. e0258450

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. 2020
  35. Germany's first COVID-19 deceased:a 59-year-old man presenting with diffuse alveolar damage due to SARS-CoV-2 infection

    Heinrich, F., Sperhake, J-P., Heinemann, A., Mushumba, H., Lennartz, M., Nörz, D., Glatzel, M., Lütgehetmann, M. & Püschel, K., 04.09.2020, In: VIRCHOWS ARCH. 477, 3, p. 335-339 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Clinical evaluation of five different automated SARS-CoV-2 serology assays in a cohort of hospitalized COVID-19 patients

    Pflüger, L. S., Bannasch, J. H., Brehm, T. T., Pfefferle, S., Hoffmann, A., Nörz, D., van der Meirschen, M., Kluge, S., Haddad, M., Pischke, S., Hiller, J., Addo, M. M., Lohse, A. W., Wiesch, J. S. Z., Peine, S., Aepfelbacher, M. & Lütgehetmann, M., 09.2020, In: J CLIN VIROL. 130, p. 104549

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. SARS-CoV-2 renal tropism associates with acute kidney injury

    Braun, F., Lütgehetmann, M., Pfefferle, S., Wong, M. N., Carsten, A., Lindenmeyer, M. T., Nörz, D., Heinrich, F., Meißner, K., Wichmann, D., Kluge, S., Gross, O., Pueschel, K., Schröder, A. S., Edler, C., Aepfelbacher, M., Puelles, V. G. & Huber, T. B., 29.08.2020, In: LANCET. 396, 10251, p. 597-598 2 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Clinical evaluation of a SARS-CoV-2 RT-PCR assay on a fully automated system for rapid on-demand testing in the hospital setting

    Nörz, D., Fischer, N., Schultze, A., Kluge, S., Mayer-Runge, U., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 07.2020, In: J CLIN VIROL. 128, p. 104390

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Complete Genome Sequence of a SARS-CoV-2 Strain Isolated in Northern Germany

    Pfefferle, S., Huang, J., Nörz, D., Indenbirken, D., Lütgehetmann, M., Oestereich, L., Günther, T., Grundhoff, A., Aepfelbacher, M. & Fischer, N., 04.06.2020, In: MICROBIOL RESOUR ANN. 9, 23

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Detection of C. difficile toxin as a model assay for performing fully automated high-throughput RT-PCR on clinical stool samples

    Eigner, U., Nörz, D., Reucher, S., Furrer, J., Sun, J., Chu, K., Kolb, M., Hefner, N., Pfefferle, S. & Lütgehetmann, M., 05.2020, In: J MICROBIOL METH. 172, p. 105882

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system

    Pfefferle, S., Reucher, S., Nörz, D. S. & Lütgehetmann, M., 04.03.2020, In: EUROSURVEILLANCE. 25, 9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. 2016
  43. Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4

    Grottke, A., Ewald, F., Lange, T., Nörz, D., Herzberger, C., Bach, J., Grabinski, N., Gräser, L., Höppner, F., Nashan, B., Schumacher, U. & Jücker, M., 2016, In: PLOS ONE. 11, 1, p. e0146370

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. 2015
  45. Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasion

    Nörz, D., Grottke, A., Bach, J., Herzberger, C., Hofmann, B. T., Nashan, B., Jücker, M. & Ewald, F., 11.2015, In: CELL SIGNAL. 27, 11, p. 2191-200 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Vertical Targeting of AKT and mTOR as Well as Dual Targeting of AKT and MEK Signaling Is Synergistic in Hepatocellular Carcinoma

    Ewald, F., Nörz, D., Grottke, A., Bach, J., Herzberger, C., Hofmann, B. T., Nashan, B. & Jücker, M., 2015, In: J CANCER. 6, 12, p. 1195-205 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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