Research ExplorerScientific StaffAlexander Stein Publications

Alexander Stein

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Affiliations
ORCID: 0000-0002-9768-0086
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Publications

  1. 2018

  2. Safety profile of trifluridine/tipiracil monotherapy in clinical practice: results of the German compassionate-use program for patients with metastatic colorectal cancer

    Kasper, S., Kisro, J., Fuchs, M., Müller, C., Schulz-Abelius, A., Karthaus, M., Rafiyan, M-R. & Stein, A., 16.11.2018, In: BMC CANCER. 18, 1, p. 1124

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Spätfolgen einer Krebsbehandlung im Kindes- und Jugendalter: Eine Herausforderung für die Transitionsmedizin

    Gebauer, J., Lehnert, H., Schmid, S. M., Spix, C., Stein, A. & Langer, T., 11.2018, In: INTERNIST. 59, 11, p. 1157-1162 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Education

  4. Spätfolgen einer Krebsbehandlung im Kindes-und Jugendalter: Eine Herausforderung für die Transtionsmedizin

    Gebauer, J., Lehnert, H., Schmid, H. S., Spix, C., Stein, A. & Langer, T., 11.2018, In: INTERNIST. 2018, 11, p. 1157-1162

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Multi-omic based molecular profiling of advanced cancer identifies treatable targets and improves survival in individual patients

    Samsen, A., von der Heyde, S., Bokemeyer, C., David, K. A., Flath, B., Graap, M., Grebenstein, B., Heflik, L., Hollburg, W., Layer, P., von Leitner, E., Overkamp, F., Saeger, W., Schneider, S., von Seydewitz, C-U., Stang, A., Stein, A., Zornig, C. & Juhl, H., 05.10.2018, In: ONCOTARGET. 9, 78, p. 34794-34809 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Immuno-oncology in GI tumours: Clinical evidence and emerging trials of PD-1/PD-L1 antagonists

    Stein, A., Markus, M., Jörg, T., Eray, G. & Vogel, A., 10.2018, In: CRIT REV ONCOL HEMAT. 130, p. 13-26 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Transfer

  7. Preventing adverse events of chemotherapy by educating patients about the nocebo effect (RENNO study) - study protocol of a randomized controlled trial with gastrointestinal cancer patients

    Quidde, J., Pan, Y., Salm, M., Hendi, A., Nilsson, S., Oechsle, K., Stein, A. & Nestoriuc, Y., 24.09.2018, In: BMC CANCER. 18, 1, p. 916

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Beyond Second-Line Therapy in Patients With Metastatic Colorectal Cancer: A Systematic Review

    Arnold, D., Prager, G. W., Quintela, A., Stein, A., Moreno, S., Mounedji, N. & Taieb, J., 01.04.2018, In: ANN ONCOL. 29, 4, p. 835-856 22 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review

  9. Immunotherapy of Colon Cancer

    Stein, A. & Folprecht, G., 2018, In: ONCOL RES TREAT. 41, 5, p. 282-285 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. 2017

  11. Das CARE-for-CAYA-Programm. Präventionskonzept für junge Menschen nach Krebserkrankung

    Quidde, J., Koch, B., Salchow, J., Jensen, W., von Grundherr, J., Escherich, G., Rutkowski, S. J., Schulz-Kindermann, F., Bergelt, C., Bokemeyer, C., Sokalska-Duhme, M., Bielak, S., Calaminus, G., Classen, C-F., Rössig, C., Faber, J., Faller, H., Hilgendorf, I., Langer, T., Metzler, M., Schuster, S., Niemeyer, C., Pierce, A., Reinhardt, D., Dirksen, U., Sander, A., Köhler, M. & Stein, A., 23.10.2017, In: Forum. Das offizielle Magazin der Deutschen Krebsgesellschaft e.V.. 32, 06, p. 479-484

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Versorgung von Patienten nach Krebserkrankung im Kindes-, Jugend- oder jungen Erwachsenenalter

    Quidde, J., Koch, B., Salchow, J., Jensen, W., von Grundherr, J., Escherich, G., Rutkowski, S. J., Schulz-Kindermann, F., Bergelt, C., Bokemeyer, C., Sokalska-Duhme, M., Bielak, S., Calaminus, G., Classen, C-F., Rössig, C., Faber, J., Faller, H., Hilgendorf, I., Langer, T., Metzler, M., Schuster, S., Niemeyer, C., Pierce, A., Reinhardt, D., Dirksen, U., Sander, A., Köhler, M. & Stein, A., 10.2017, In: J Onkol - Z Onkol Fortb. 2017, 10, p. 862-866

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. AIO LQ-0110: a randomized phase II trial comparing oral doxycycline versus local administration of erythromycin as preemptive treatment strategies of panitumumab-mediated skin toxicity in patients with metastatic colorectal cancer

    Kripp, M., Prasnikar, N., Vehling-Kaiser, U., Quidde, J., Al-Batran, S-E., Stein, A., Neben, K., Hannig, C. V., Tessen, H. W., Trarbach, T., Hinke, A. & Hofheinz, R-D., 23.09.2017, In: ONCOTARGET. 8, 62, p. 105061-105071 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. LBA-007FOLFOX/Bevacizumab +/- Irinotecan in advanced colorectal cancer (AIO) "CHARTA": Final results and multivariate prognostic factor analysis

    Schmoll, H-J., Garlipp, B., Junghanß, C., Leithäuser, M., Vogel, A., Schaefers, M., Kaiser, U., Hoeffkes, H-G., Florschütz, A., Rüssel, J., Kanzler, S., Edelmann, T., Forstbauer, H., Göhler, T., Hannig, C., Hildebrandt, B., Steighardt, J., Cygon, F., Meinert, F. & Stein, A., 01.06.2017, In: ANN ONCOL. 28, suppl_3

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  15. T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker

    Akyüz, N., Brandt, A., Stein, A., Schliffke, S., Mährle, T., Quidde, J., Goekkurt, E., Loges, S., Haalck, T., Ford, C., Asemissen, A. M., Thiele, B., Radloff, J., Thenhausen, T., Krohn-Grimberghe, A., Bokemeyer, C. & Binder, M., 01.06.2017, In: INT J CANCER. 140, 11, p. 2535-2544

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Successful mTOR inhibitor therapy for a metastastic neuroendocrine tumour in a patient with a germline TSC2 mutation

    Schrader, J., Henes, F. O., Perez, D., Burdak-Rothkamm, S., Stein, A., Izbicki, J. R. & Lohse, A. W., 01.04.2017, In: ANN ONCOL. 28, 4, p. 904-905

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  17. Baseline and On-Treatment Markers Determining Prognosis of First-Line Chemotherapy in Combination with Bevacizumab in Patients with Metastatic Colorectal Cancer

    Quidde, J., Denne, L., Kutscheidt, A., Kindler, M., Kirsch, A., Kripp, M., Petersen, V., Schulze, M., Seraphin, J., Tummes, D., Arnold, D. & Stein, A., 2017, In: ONCOL RES TREAT. 40, 1-2, p. 21-26 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Personalizing Maintenance Therapy in Metastatic Colorectal Cancer

    Quidde, J. & Stein, A., 2017, In: CURR COLORECT CANC R. 13, 3, p. 205-211

    Research output: SCORING: Contribution to journal › SCORING: Review article › Education

  19. 2016

  20. Improved nutrition in adolescents and young adults after childhood cancer - INAYA study

    Quidde, J., von Grundherr, J., Koch, B., Bokemeyer, C., Escherich, G., Valentini, L., Buchholz, D., Schilling, G. & Stein, A., 08.11.2016, In: BMC CANCER. 16, 1, p. 872

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis

    Tachezy, M., Gebauer, F., Janot, M., Uhl, W., Zerbi, A., Montorsi, M., Perinel, J., Adham, M., Dervenis, C., Agalianos, C., Malleo, G., Maggino, L., Stein, A., Izbicki, J. R. & Bockhorn, M., 01.07.2016, In: SURGERY. 160, 1, p. 136-44

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. A Review of Clinical Studies and Practical Guide for the Administration of Triplet Chemotherapy Regimens with Bevacizumab in First-line Metastatic Colorectal Cancer

    Loupakis, F., Stein, A., Ychou, M., Hermann, F., Salud, A. & Österlund, P., 06.2016, In: TARGET ONCOL. 11, 3, p. 293-308

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Effect of Application and Intensity of Bevacizumab-based Maintenance After Induction Chemotherapy With Bevacizumab for Metastatic Colorectal Cancer: A Meta-analysis

    Stein, A., Schwenke, C., Folprecht, G. & Arnold, D., 06.2016, In: CLIN COLORECTAL CANC. 15, 2, p. e29-39

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Multimodale Therapie des lokalisierten Magenkarzinoms

    Stein, A., Arnold, D. & Al-Batran, S-E., 06.2016, In: ONKOLOGE. 22, 6, p. 392-399

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review

  25. Treatment approach in patients with hyperbilirubinemia secondary to liver metastases in gastrointestinal malignancies: a case series and review of literature

    Quidde, J., Azémar, M., Bokemeyer, C., Arnold, D. & Stein, A., 05.2016, In: THER ADV MED ONCOL. 8, 3, p. 144-52 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Integrating patient reported measures as predictive parameters into decisionmaking about palliative chemotherapy: a pilot study

    Creutzfeldt, A., Suling, A., Oechsle, K., Mehnert, A., Atanackovic, D., Kripp, M., Arnold, D., Stein, A. & Quidde, J., 01.03.2016, In: BMC PALLIAT CARE. 15, 1, p. 25

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Capecitabine in the routine first-line treatment of elderly patients with advanced colorectal cancer - results from a non-interventional observation study

    Stein, A., Quidde, J., Schröder, J. K., Göhler, T., Tschechne, B., Valdix, A-R., Höffkes, H-G., Schirrmacher-Memmel, S., Wohlfarth, T., Hinke, A., Engelen, A. & Arnold, D., 10.02.2016, In: BMC CANCER. 16, 1, p. 82

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells

    Hvichia, G. E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R. P. L., Stoecklein, N. H., Wikman, H., Riethdorf, S., Pantel, K. & Gorges, T. M., 20.01.2016, In: INT J CANCER. 138, 12, p. 2894-904

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Improved Detection of Circulating Tumor Cells in Metastatic Colorectal Cancer by the Combination of the CellSearch® System and the AdnaTest®

    Gorges, T. M., Stein, A., Quidde, J., Hauch, S., Röck, K., Riethdorf, S., Joosse, S. A. & Pantel, K., 2016, In: PLOS ONE. 11, 5, p. e0155126

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. 2015

  31. Reduced dosage of bevacizumab in treatment of vestibular schwannomas in patients with neurofibromatosis type 2

    Farschtschi, S., Kollmann, P., Dalchow, C., Stein, A. & Mautner, V-F., 12.2015, In: EUR ARCH OTO-RHINO-L. 272, 12, p. 3857-60 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. A phase II study of catumaxomab administered intra- and postoperatively as part of a multimodal approach in primarily resectable gastric cancer

    Bokemeyer, C., Stein, A., Ridwelski, K., Atanackovic, D., Arnold, D., Wöll, E., Ulrich, A., Fischer, R., Krüger, C. & Schuhmacher, C., 18.10.2015, In: GASTRIC CANCER. 18, 4, p. 833-842

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Upfront FOLFOXIRI+bevacizumab followed by fluoropyrimidin and bevacizumab maintenance in patients with molecularly unselected metastatic colorectal cancer

    Stein, A., Atanackovic, D., Hildebrandt, B., Stübs, P., Brugger, W., Hapke, G., Steffens, C-C., Illerhaus, G., Bluemner, E., Stöhlmacher, J. & Bokemeyer, C., 15.09.2015, In: BRIT J CANCER. 113, 6, p. 872-7 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Adjuvant chemotherapy with gemcitabine and cisplatin compared to observation after curative intent resection of cholangiocarcinoma and muscle invasive gallbladder carcinoma (ACTICCA-1 trial) - a randomized, multidisciplinary, multinational phase III trial

    Stein, A., Arnold, D., Bridgewater, J., Goldstein, D., Jensen, L. H., Klümpen, H-J., Lohse, A. W., Nashan, B., Primrose, J., Schrum, S., Shannon, J., Vettorazzi, E. & Wege, H., 31.07.2015, In: BMC CANCER. 15, p. Art. 564

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer

    Braig, F., März, M., Schieferdecker, A., Schulte, A., Voigt, M., Stein, A., Grob, T., Alawi, M., Indenbirken, D., Kriegs, M., Engel, E., Vanhoefer, U., Grundhoff, A., Loges, S., Riecken, K., Fehse, B., Bokemeyer, C. & Binder, M., 20.05.2015, In: ONCOTARGET. 6, 14, p. 12035-47 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 73-jährige leber- und nierentransplantierte Patientin mit dumpfen Oberbauchschmerzen und rezidivierendem Nasenbluten

    Zinser, M. E., Salzer, H. J. F., Stein, A., von Petersdorff-Campen, M., Koops, A. & Holzhüter, J., 05.2015, In: INTERNIST. 56, 5, p. 566-72 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Bevacizumab plus chemotherapy as first-line treatment for patients with metastatic colorectal cancer: results from a large German community-based observational cohort study

    Stein, A., Petersen, V., Schulze, M., Seraphin, J., Hoeffkes, H-G., Valdix, A. R., Schroeder, J., Herrenberger, J., Boxberger, F., Leutgeb, B., Hinke, A., Kutscheidt, A. & Arnold, D., 01.02.2015, In: ACTA ONCOL. 54, 2, p. 171-8 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. 2014

  39. Phenotyping of peripheral blood mononuclear cells of patients with advanced heavily pre-treated adenocarcinoma of the stomach and gastro-esophageal junction

    Kuehnle, M-C., Attig, S., Britten, C. M., Schulze-Bergkamen, H., Lordick, F., von Wichert, G., Thuss-Patience, P., Stein, A., Schuler, M., Bassermann, F., Sahin, U. & Türeci, O., 01.12.2014, In: CANCER IMMUNOL IMMUN. 63, 12, p. 1273-84 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Continuous tissue microarray based identification of cancers with homogeneous target expression for successful targeted therapy in clinical routine practice

    Burandt, E., Schreiber, M., Stein, A., Minner, S., Clauditz, T. S., Bokemeyer, C., Jänicke, F., Fisch, M., Izbicki, J. R., Knecht, R., Sauter, G. & Stahl, P. R., 01.03.2014, In: GENE CHROMOSOME CANC. 53, 3, p. 228-39 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Docetaxel, oxaliplatin and capecitabine (TEX regimen) in patients with metastatic gastric or gastro-esophageal cancer: results of a multicenter phase I/II study

    Stein, A., Arnold, D., Thuss-Patience, P. C., Moehler, M., Grothe, W., Seufferlein, T., Reinacher-Schick, A., Geissler, M., Hofheinz, R-D. & Schmoll, H-J., 03.2014, In: ACTA ONCOL. 53, 3, p. 392-8 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. How to select the optimal treatment for first line metastatic colorectal cancer

    Stein, A. & Bokemeyer, C., 28.01.2014, In: WORLD J GASTROENTERO. 20, 4, p. 899-907 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Bevacizumab in first-line treatment of elderly patients with metastatic colorectal cancer: German community-based observational cohort study results

    Hofheinz, R., Petersen, V., Kindler, M., Schulze, M., Seraphin, J., Hoeffkes, H-G., Valdix, A-R., Schroeder, J., Herrenberger, J., Stein, A., Hinke, A. & Arnold, D., 01.01.2014, In: BMC CANCER. 14, p. 761

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Colorectal cancer in 2013: Towards improved drugs, combinations and patient selection

    Schmoll, H-J. & Stein, A., 2014, In: NAT REV CLIN ONCOL. 11, 2, p. 79-80 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  45. Exercise training in patients with advanced gastrointestinal cancer undergoing palliative chemotherapy: a pilot study

    Jensen, W., Baumann, F. T., Stein, A., Bloch, W., Bokemeyer, C., de Wit, M. & Oechsle, K., 2014, In: SUPPORT CARE CANCER. 22, 7, p. 1797-806 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Neue Substanzen für die Therapie solider Tumoren

    Stein, A. & Bokemeyer, C., 2014, In: Forum. Das offizielle Magazin der Deutschen Krebsgesellschaft e.V.. 29, p. 300-4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Survivorship-Programme: Ziele und Inhalte einer strukturierten Betreuung

    Schilling, G., Stein, A., Quidde, J. & Bokemeyer, C., 2014, In: Forum. Das offizielle Magazin der Deutschen Krebsgesellschaft e.V.. 3, 29, p. 202-205

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. 2013

  49. Optimum Duration of Metastatic Colorectal Cancer Treatment

    Stein, A. & Schmoll, H-J., 09.2013, In: CURR COLORECT CANC R. 9, 3, p. 223-29

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  50. Prolonging Survival Through a Personalized Approach in Metastatic Colorectal Cancer

    Stein, A. & Bokemeyer, C., 09.2013, In: J OncoPathol. 1, 3, p. 31-41

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  51. New developments in the second-line treatment of metastatic colorectal cancer: potential place in therapy

    Arnold, D. & Stein, A., 01.06.2013, In: DRUGS. 73, 9, p. 883-91 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  52. Systemic treatment of liver metastases from colorectal cancer

    Stein, A. & Schmoll, H-J., 01.05.2013, In: THER ADV MED ONCOL. 5, 3, p. 193-203 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  53. Oxaliplatin for colorectal cancer: recent evidence from clinical trials

    Stein, A., Quidde, J. & Arnold, D., 02.2013, In: COLORECTAL CANCER. p. 135-44

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review

  54. Cancer patients and advance directives: a survey of patients in a hematology and oncology outpatient clinic

    Hubert, E., Schulte, N., Belle, S., Gerhardt, A., Merx, K., Hofmann, W-K., Stein, A., Burkholder, I., Hofheinz, R-D. & Kripp, M., 01.01.2013, In: ONKOLOGIE. 36, 7-8, p. 398-402 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. Capecitabine and bevacizumab for non-resectable metastatic colorectal cancer patients: final results from phase II AIO KRK 0105 trial

    Stein, A., Kretzschmar, A., Behringer, D., Wolff, T., Zimber, J., Hegewisch-Becker, S., Kettner, E., Pflüger, K-H., Kirsch, A. & Arnold, D., 01.01.2013, In: BMC CANCER. 13, p. 454

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. Antiangiogenese-Therapie beim kolorektalen Karzinom

    Arnold, D. & Stein, A., 01.2013, In: Onkologie heute. p. 32-35

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer

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