I. Medical Clinic and Polyclinic
Publications
- 2012
[Prevention of nosocomial transmission of human immunodeficiency virus (HIV) from HIV-positive healthcare workers. Recommendations of the German Association for the Control of Viral Diseases (DVV) e.V. and the Society for Virology (GfV) e.V].
Rabenau, H. F., Gottschalk, R., Gürtler, L., Haberl, A. E., Hamouda, O., Himmelreich, H., Korn, K., Mertens, T., Schmidt, K. W., Schmiedel, S., Spickhoff, A., Wirz, G., Wutzler, P. & Wicker, S., 2012, In: BUNDESGESUNDHEITSBLA. 55, 8, p. 937-943 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
Bierwolf, J., Lütgehetmann, M., Deichmann, S., Erbes, J., Volz, T., Dandri-Petersen, M., Cohen, S., Nashan, B. & Pollok, J-M., 2012, In: TISSUE ENG PT A. 18, 13-14, p. 1443-1453 13-14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Pyogenic liver abscess: a retrospective patient study].
Zenouzi, R., Schmiedel, S. & Lohse, A. W., 2012, In: Z GASTROENTEROL. 50, 6, p. 578-584 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin.
Larrey, D., Lohse, A. W., de Ledinghen, V., Trepo, C., Gerlach, T., Zarski, J-P., Tran, A., Mathurin, P., Thimme, R., Arastéh, K., Trautwein, C., Cerny, A., Dikopoulos, N., Schuchmann, M., Heim, M. H., Gerken, G., Stern, J. O., Wu, K., Abdallah, N., Girlich, B., Scherer, J., Berger, F., Marquis, M., Kukolj, G., Böcher, W. & Steffgen, J., 2012, In: J HEPATOL. 57, 1, p. 39-46 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 [AEZS- 108].
Szepeshazi, K., Schally, A. V., Keller, G., Block, N. L., Benten, D., Halmos, G., Szalontay, L., Vidaurre, I., Jaszberenyi, M. & Rick, F. G., 2012, In: ONCOTARGET. 3, 7, p. 686-699 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulatory T cell frequencies do not correlate with breadth or magnitude of HIV-1-specific T cell responses.
Angin, M., Streeck, H., Wen, F., King, M., Pereyra, F., Altfeld, M., Walker, B. D. & Addo, M., 2012, In: AIDS RES HUM RETROV. 28, 8, p. 749-751 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking : Vielfarbige Zellmarkierung zur klonalen Analyse
Riecken, K., Thomaschewski, M., Warlich, M., Cornils, K., Benten, D. & Fehse, B., 2012, In: Laborwelt. 13, 1, p. 7-9 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking with lentiviral vectors for multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Benten, D. & Fehse, B., 2012, In: NAT PHYS. 7, 5, p. 839-849 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Kah, J., Wüstenberg, A., Keller, A., Sirma, H., Montalbano, R., Ocker, M., Volz, T., Dandri-Petersen, M., Tiegs, G. & Sass, G., 2012, In: ONCOL REP. 28, 3, p. 1077-1083 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stereoselective synthesis of D- and L-carbocyclic nucleosides by enzymatically catalyzed kinetic resolution.
Mahler, M., Reichardt, B., Hartjen, P., van Lunzen, J. & Meier, C., 2012, In: CHEM-EUR J. 18, 35, p. 11046-11062 35.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Volz, T., Lütgehetmann, M., Allweiss, L., Warlich, M., Bierwolf, J., Pollok, J-M., Petersen, J., Matthes, E. & Dandri-Petersen, M., 2012, In: ANTIVIR THER. 17, 4, p. 623-631 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systemtherapie des Leberzellkarzinoms
Wege, H. & Arnold, D., 2012, In: ONKOLOGE. 18, 7, p. 602-610 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.
Fraedrich, K., Schrader, J., Ittrich, H., von Amsberg, G., Gontarewicz, A., Matzat, V., Kromminga, A., Pace, A., Moll, J., Bläker, M., Lohse, A. W., Hörsch, D., Brümmendorf, T. & Benten, D., 2012, In: CLIN CANCER RES. 18, 17, p. 4621-4632 17.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Th17 cells bound for the liver: group tourists or private travellers?
Carambia, A. & Herkel, J., 2012, In: J HEPATOL. 57, 5, p. 943-945 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The indications for liver biopsy.
Tannapfel, A., Dienes, H-P. & Lohse, A. W., 2012, In: DTSCH ARZTEBL INT. 109, 27-28, p. 477-483 27-28.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Travel-related imported infections in Europe, EuroTravNet 2009.
Odolini, S., Parola, P., Gkrania-Klotsas, E., Caumes, E., Schlagenhauf, P., López-Vélez, R., Burchard, G-D., Santos-O'Connor, F., Weld, L., von Sonnenburg, F., Field, V., de Vries, P., Jensenius, M., Loutan, L. & Castelli, F., 2012, In: CLIN MICROBIOL INFEC. 18, 5, p. 468-474 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment adherence - room for improvement, not only in autoimmune hepatitis.
Weiler-Normann, C. & Lohse, A. W., 2012, In: J HEPATOL. 57, 6, p. 1168-1170 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment of AIDS-related lymphomas: rituximab is beneficial even in severely immunosuppressed patients.
Wyen, C., Jensen, B., Hentrich, M., Siehl, J., Sabranski, M., Esser, S., Gillor, D., Müller, M., van Lunzen, J., Wolf, T., Bogner, J. R., Wasmuth, J. C., Christ, H., Fätkenheuer, G. & Hoffmann, C., 2012, In: AIDS. 26, 4, p. 457-464 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Viruses acquired abroad: what does the primary care physician need to know?
Schmidt-Chanasit, J., Schmiedel, S., Fleischer, B. & Burchard, G-D., 2012, In: DTSCH ARZTEBL INT. 109, 41, p. 681-692 41.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Characterization of Enterobacter cloacae pneumonia: a single-center retrospective analysis.
Hennigs, J. K., Baumann, H. J., Schmiedel, S., Tennstedt, P., Sobottka, I., Bokemeyer, C., Kluge, S. & Klose, H., 01.12.2011, In: LUNG. 189, 6, p. 475-483 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The induction of mild hypothermia improves systolic function of the resuscitated porcine heart at no further sympathetic activation
Schwarzl, M., Steendijk, P., Huber, S., Truschnig-Wilders, M., Obermayer-Pietsch, B., Maechler, H., Pieske, B. & Post, H., 01.12.2011, In: ACTA PHYSIOL. 203, 4, p. 409-18 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis
Kluwe, J., Wongsiriroj, N., Troeger, J. S., Gwak, G-Y., Dapito, D. H., Pradere, J-P., Jiang, H., Siddiqi, M., Piantedosi, R., O'Byrne, S. M., Blaner, W. S. & Schwabe, R. F., 09.2011, In: GUT. 60, 9, p. 1260-8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Entecavir treatment for chronic hepatitis B: adaptation is not needed for the majority of naïve patients with a partial virological response
Zoutendijk, R., Reijnders, J. G. P., Brown, A., Zoulim, F., Mutimer, D., Deterding, K., Petersen, J., Hofmann, W. P., Buti, M., Santantonio, T., van Bömmel, F., Pradat, P., Oo, Y., Lütgehetmann, M., Berg, T., Hansen, B. E., Wedemeyer, H., Janssen, H. L. A. & VIRGIL Surveillance Study Group, 08.2011, In: HEPATOLOGY. 54, 2, p. 443-51 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adjusting for heterogeneity of malaria transmission in longitudinal studies
Bousema, T., Kreuels, B. & Gosling, R., 01.07.2011, In: J INFECT DIS. 204, 1, p. 1-3 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A randomized, double-blind, multicenter phase II AIO trial with gemcitabine plus sorafenib versus gemcitabine plus placebo in patients with chemotherapy-naive advanced or metastatic biliary tract cancer: First safety and efficacy data
Moehler, M. H., Schimanski, C. C., Kanzler, S., Woerns, M. A., Denzer, U., Kolligs, F. T., Ebert, M. P., Distelrath, A., Geissler, M., Zeuzem, S., Lammert, F., Lohse, A. W., Dollinger, M. M., Lindig, U., Duerr, E. M., Lubomierski, N., Zimmermann, S., Kabisch, M., Schadmann-Fischer, S., Galle, P. R. & German AIO, 20.05.2011, In: J CLIN ONCOL. 29, 15_suppl, p. 4077Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology.
Kamanaka, M., Huber, S., Zenewicz, L. A., Gagliani, N., Rathinam, C., O'Connor, W., Wan, Y. Y., Nakae, S., Iwakura, Y., Hao, L. & Flavell, R. A., 09.05.2011, In: J EXP MED. 208, 5, p. 1027-1040 14 p., 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner
Huber, S., Gagliani, N., Esplugues, E., O'Connor, W., Huber, F. J., Chaudhry, A., Kamanaka, M., Kobayashi, Y., Booth, C. J., Rudensky, A. Y., Roncarolo, M. G., Battaglia, M. & Flavell, R. A., 22.04.2011, In: IMMUNITY. 34, 4, p. 554-565 12 p., 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL3 variant on chromosomal region 5q31-33 and protection from recurrent malaria attacks
Meyer, C. G., Calixto Fernandes, M. H., Intemann, C. D., Kreuels, B., Kobbe, R., Kreuzberg, C., Ayim, M., Ruether, A., Loag, W., Ehmen, C., Adjei, S., Adjei, O., Horstmann, R. D. & May, J., 15.03.2011, In: HUM MOL GENET. 20, 6, p. 1173-81 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human cord blood CD4+CD25hi regulatory T cells suppress prenatally acquired T cell responses to Plasmodium falciparum antigens
Mackroth, M. S., Malhotra, I., Mungai, P., Koech, D., Muchiri, E. & King, C. L., 01.03.2011, In: J IMMUNOL. 186, 5, p. 2780-91 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Follow-up survey of children who received sulfadoxine-pyrimethamine for intermittent preventive antimalarial treatment in infants
Kobbe, R., Hogan, B., Adjei, S., Klein, P., Kreuels, B., Loag, W., Adjei, O. & May, J., 15.02.2011, In: J INFECT DIS. 203, 4, p. 556-60 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatocyte IKK2 protects Mdr2-/- mice from chronic liver failure
Ehlken, H., Kondylis, V., Heinrichsdorff, J., Ochoa-Callejero, L., Roskams, T. & Pasparakis, M., 01.01.2011, In: PLOS ONE. 6, 10, p. e25942Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
Melum, E., Franke, A., Schramm, C., Weismüller, T. J., Gotthardt, D. N., Offner, F. A., Juran, B. D., Laerdahl, J. K., Labi, V., Björnsson, E., Weersma, R. K., Henckaerts, L., Teufel, A., Rust, C., Ellinghaus, E., Balschun, T., Boberg, K. M., Ellinghaus, D., Bergquist, A., Sauer, P., Ryu, E., Hov, J. R., Wedemeyer, J., Lindkvist, B., Wittig, M., Porte, R. J., Holm, K., Gieger, C., Wichmann, H-E., Stokkers, P., Ponsioen, C. Y., Runz, H., Stiehl, A., Wijmenga, C., Sterneck, M., Vermeire, S., Beuers, U., Villunger, A., Schrumpf, E., Lazaridis, K. N., Manns, M. P., Schreiber, S. & Karlsen, T. H., 01.2011, In: NAT GENET. 43, 1, p. 17-19 3 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primär sklerosierende Cholangitis - Herausforderungen gemeinsam meistern. Die Deutsche PSC-Studiengruppe
Schramm, C., Gotthardt, D., Spengler, U., Schirmacher, P. & Weismüller, T., 01.2011, In: Z GASTROENTEROL. 49, 1, p. 63-65 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A new experimental model to allow use of clinical-scale endoscopes in small-animal tumor models.
Anders, M., Frimberger, E., Odau, S., Wiedenmann, B. & Rösch, T., 2011, In: J GASTROINTEST ONCOL. 2, 2, p. 64-69 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antibody dynamics and spontaneous viral clearance in patients with acute hepatitis C infection in Rio de Janeiro, Brazil.
Strasak, A. M., Kim, A. Y., Lauer, G. M., Sousa, D., Paulo, S., Ginuino, C. F., Fernandes, C. A., Velloso, C. E., Almeida, D., Adilson, J., Schulze Zur Wiesch, J., Jaqueline, M., Yoshida, C. F., Julian, S. Z. W., Paranhos-Baccalá, G., Lang, S., Brant, L. J., Ulmer, H., Strohmaier, S., Kaltenbach, L., Lampe, E. & Lewis-Ximenez, L. L., 2011, In: BMC INFECT DIS. 11, p. 15Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Association of a common mineralocorticoid receptor gene polymorphism with salivary cortisol in healthy adults.
Muhtz, C., Zyriax, B-C., Bondy, B., Windler, E. & Otte, C., 2011, In: PSYCHONEUROENDOCRINO. 36, 2, p. 298-301 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Autoimmune hepatitis.
Lohse, A. W. & Mieli-Vergani, G., 2011, In: J HEPATOL. 55, 1, p. 171-182 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Buruli-Ulkus - Diagnose und Therapie der infektiösen tropischen Hauterkrankung
Burchard, G-D., 2011, In: FLUGMEDIZIN TROPENME. 18, 2, p. 80-82 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Case report of aseptic meningitis in a patient with Crohn's disease under infliximab therapy.
Manthey, C., Lohse, A. W. & Pace, A., 2011, In: INFLAMM BOWEL DIS. 17, 2, p. 10 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Central Africa
Burchard, G-D. & Ehrhardt, S., 2011, Infectious Diseases: A Geographic Guide. WileyBlackwell, London, p. 84-97 14 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Chronic inflammatory IFN-γ signaling suppresses hepatocarcinogenesis in mice by sensitizing hepatocytes for apoptosis.
Lüth, S., Schrader, J., Zander, S., Carambia, A., Buchkremer, J., Huber, S., Reifenberg, K., Yamamura, K-I., Schirmacher, P., Lohse, A. W. & Herkel, J., 2011, In: CANCER RES. 71, 11, p. 3763-3771 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical outcome of HIV-infected patients with discordant virological and immunological response to antiretroviral therapy.
Zoufaly, A., An der Heiden, M., Kollan, C., Bogner, J. R., Fätkenheuer, G., Wasmuth, J. C., Stoll, M., Hamouda, O. & van Lunzen, J., 2011, In: J INFECT DIS. 203, 3, p. 364-371 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease.
Schulze Zur Wiesch, J., Thomssen, A., Hartjen, P., Toth, I., Lehmann, C., Meyer-Olson, D., Colberg, K., Frerk, S., Babikir, D., Schmiedel, S., Degen, O., Mauss, S., Rockstroh, J., Staszewski, S., Khaykin, P., Strasak, A., Lohse, A. W., Fätkenheuer, G., Hauber, J. & van Lunzen, J., 2011, In: J VIROL. 85, 3, p. 1287-1297 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Control of TH17 cells occurs in the small intestine.
Esplugues, E., Huber, S., Gagliani, N., Hauser, A. E., Town, T., Wan, Y. Y., O'Connor, W., Rongvaux, A., Nico, V. R., Haberman, A. M., Iwakura, Y., Kuchroo, V. K., Kolls, J. K., Bluestone, J. A., Herold, K. C. & Flavell, R. A., 2011, In: NATURE. 475, 7357, p. 514-518 7357.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis.
Erhardt, A., Wegscheid, C., Claaß, B., Carambia, A., Herkel, J., Mittrücker, H. W., Panzer, U. & Tiegs, G., 2011, In: J IMMUNOL. 186, 9, p. 5284-5293 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Der besondere Fall · Suizidversuch mit Knollenblätterpilz
Harlandt, O., Wichmann, D., de Heer, G., Fischer, L., Nashan, B., Reimer, J., Benten, D., Lohse, A. W. & Kluge, S., 2011, In: Hamb Ärztebl. 65, 5, p. 34-35 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Der Malariaimpfstoff RTS, S
Burchard, G-D., 2011, In: Kinderärztliche Praxis. 82, p. 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Desperately seeking diarrhoea: outbreak of haemolytic uraemic syndrome caused by emerging sorbitol-fermenting shiga toxin-producing Escherichia coli O157:H-, Germany, 2009.
Nielsen, S., Frank, C., Fruth, A., Spode, A., Prager, R., Graff, A., Plenge-Bönig, A., Loos, S., Lütgehetmann, M., Kemper, M. J., Müller-Wiefel, D. E. & Werber, D., 2011, In: ZOONOSES PUBLIC HLTH. 58, 8, p. 567-572 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Diagnosis and therapy of cutaneous and mucocutaneous Leishmaniasis in Germany].
Boecken, G., Sunderkötter, C., Bogdan, C., Weitzel, T., Fischer, M., Müller, A., Löbermann, M., Anders, G., von Stebut, E., Schunk, M., Burchard, G-D., Grobusch, M., Bialek, R., Harms-Zwingenberger, G., Fleischer, B., Pietras, M., Faulde, M., Erkens, K., Dermatology, G. S. O., Medicine, G. S. O. T. & Chemotherapy, G. S. O., 2011, In: J DTSCH DERMATOL GES. 9 Suppl 8, p. 1-51Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic criteria for autoimmune hepatitis.
Lohse, A. W. & Wiegard, C., 2011, In: BEST PRACT RES CL GA. 25, 6, p. 665-671 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review