Research ExplorerJournalsSCI TRANSL MED Publications

SCI TRANSL MED - Science Translational Medicine

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Publications

  1. 2024

  2. Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice

    Jahn, D., Knapstein, P. R., Otto, E., Köhli, P., Sevecke, J., Graef, F., Graffmann, C., Fuchs, M., Jiang, S., Rickert, M., Erdmann, C., Appelt, J., Revend, L., Küttner, Q., Witte, J., Rahmani, A., Duda, G., Xie, W., Donat, A., Schinke, T., Ivanov, A., Tchouto, M. N., Beule, D., Frosch, K-H., Baranowsky, A., Tsitsilonis, S. & Keller, J., 17.04.2024, In: SCI TRANSL MED. 16, 743, p. eadk9129

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. 2023

  4. CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12

    Paust, H-J., Song, N., De Feo, D., Asada, N., Tuzlak, S., Zhao, Y., Riedel, J-H., Hellmig, M., Sivayoganathan, A., Peters, A., Kaffke, A., Borchers, A., Wenzel, U. O., Steinmetz, O. M., Tiegs, G., Meister, E., Mack, M., Kurts, C., von Vietinghoff, S., Lindenmeyer, M. T., Hoxha, E., Stahl, R. A. K., Huber, T. B., Bonn, S., Meyer-Schwesinger, C., Wiech, T., Turner, J-E., Becher, B., Krebs, C. F. & Panzer, U., 15.03.2023, In: SCI TRANSL MED. 15, 687, eadd6137.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. 2022

  6. Treatment of a genetic brain disease by CNS-wide microglia replacement

    Shibuya, Y., Kumar, K. K., Mader, M. M-D., Yoo, Y., Ayala, L. A., Zhou, M., Mohr, M. A., Neumayer, G., Kumar, I., Yamamoto, R., Marcoux, P., Liou, B., Bennett, F. C., Nakauchi, H., Sun, Y., Chen, X., Heppner, F. L., Wyss-Coray, T., Südhof, T. C. & Wernig, M., 16.03.2022, In: SCI TRANSL MED. 14, 636, eabl9945.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. PIEZO1 mediates a mechanothrombotic pathway in diabetes

    Zhu, W., Guo, S., Homilius, M., Nsubuga, C., Wright, S. H., Quan, D., Kc, A., Eddy, S. S., Victorio, R. A., Beerens, M., Flaumenhaft, R., Deo, R. C. & MacRae, C. A., 05.01.2022, In: SCI TRANSL MED. 14, 626, eabk1707.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. 2021

  9. Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue

    Radke, M. H., Badillo-Lisakowski, V., Britto-Borges, T., Kubli, D. A., Jüttner, R., Parakkat, P., Carballo, J. L., Hüttemeister, J., Liss, M., Hansen, A., Dieterich, C., Mullick, A. E. & Gotthardt, M., 01.12.2021, In: SCI TRANSL MED. 13, 622, eabe8952.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. 2020

  11. Vulnerability to reservoir reseeding due to high immune activation after allogeneic hematopoietic stem cell transplantation in individuals with HIV-1

    Eberhard, J. M., Angin, M., Passaes, C., Salgado, M., Monceaux, V., Knops, E., Kobbe, G., Jensen, B., Christopeit, M., Kröger, N., Vandekerckhove, L., Badiola, J., Bandera, A., Raj, K., van Lunzen, J., Hütter, G., Kuball, J. H. E., Martinez-Laperche, C., Balsalobre, P., Kwon, M., Díez-Martín, J. L., Nijhuis, M., Wensing, A., Martinez-Picado, J., Schulze Zur Wiesch, J. & Sáez-Cirión, A., 06.05.2020, In: SCI TRANSL MED. 12, 542

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation

    Jobin, K., Stumpf, N. E., Schwab, S., Eichler, M., Neubert, P., Rauh, M., Adamowski, M., Babyak, O., Hinze, D., Sivalingam, S., Weisheit, C., Hochheiser, K., Schmidt, S. V., Meissner, M., Garbi, N., Abdullah, Z., Wenzel, U., Hölzel, M., Jantsch, J. & Kurts, C., 25.03.2020, In: SCI TRANSL MED. 12, 536

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. 2019

  14. Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases

    Jurmeister, P., Bockmayr, M., Seegerer, P., Bockmayr, T., Treue, D., Montavon, G., Vollbrecht, C., Arnold, A., Teichmann, D., Bressem, K., Schüller, U., von Laffert, M., Müller, K-R., Capper, D. & Klauschen, F., 11.09.2019, In: SCI TRANSL MED. 11, 509

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation

    Scherschel, K., Hedenus, K., Jungen, C., Lemoine, M. D., Rübsamen, N., Veldkamp, M. W., Klatt, N., Lindner, D., Westermann, D., Casini, S., Kuklik, P., Eickholt, C., Klöcker, N., Shivkumar, K., Christ, T., Zeller, T., Willems, S. & Meyer, C., 22.05.2019, In: SCI TRANSL MED. 11, 493

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. 2018

  17. Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand

    Luther, J., Yorgan, T. A., Rolvien, T., Ulsamer, L., Koehne, T., Liao, N., Keller, D., Vollersen, N., Teufel, S., Neven, M., Peters, S., Schweizer, M., Trumpp, A., Rosigkeit, S., Bockamp, E., Mundlos, S., Kornak, U., Oheim, R., Amling, M., Schinke, T. & David, J-P., 07.11.2018, In: SCI TRANSL MED. 10, 466, p. eaau7137

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Thy-1 (CD90) promotes bone formation and protects against obesity

    Picke, A-K., Campbell, G. M., Blüher, M., Krügel, U., Schmidt, F. N., Tsourdi, E., Winzer, M., Rauner, M., Vukicevic, V., Busse, B., Salbach-Hirsch, J., Tuckermann, J. P., Simon, J. C., Anderegg, U., Hofbauer, L. C. & Saalbach, A., 08.08.2018, In: SCI TRANSL MED. 10, 453, p. eaao6806

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection

    Winer, B. Y., Shirvani-Dastgerdi, E., Bram, Y., Sellau, J., Low, B. E., Johnson, H., Huang, T., Hrebikova, G., Heller, B., Sharon, Y., Giersch, K., Gerges, S., Seneca, K., Pais, M-A., Frankel, A. S., Chiriboga, L., Cullen, J., Nahass, R. G., Lutgehetmann, M., Toettcher, J. E., Wiles, M. V., Schwartz, R. E. & Ploss, A., 27.06.2018, In: SCI TRANSL MED. 10, 447, p. eaap9328

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Oncogenic JAK2causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

    Prestipino, A., Emhardt, A. J., Aumann, K., O'Sullivan, D., Gorantla, S. P., Duquesne, S., Melchinger, W., Braun, L., Vuckovic, S., Boerries, M., Busch, H., Halbach, S., Pennisi, S., Poggio, T., Apostolova, P., Veratti, P., Hettich, M., Niedermann, G., Bartholomä, M., Shoumariyeh, K., Jutzi, J. S., Wehrle, J., Dierks, C., Becker, H., Schmitt-Graeff, A., Follo, M., Pfeifer, D., Rohr, J., Fuchs, S., Ehl, S., Hartl, F. A., Minguet, S., Miething, C., Heidel, F. H., Kröger, N., Triviai, I., Brummer, T., Finke, J., Illert, A. L., Ruggiero, E., Bonini, C., Duyster, J., Pahl, H. L., Lane, S. W., Hill, G. R., Blazar, B. R., von Bubnoff, N., Pearce, E. L. & Zeiser, R., 21.02.2018, In: SCI TRANSL MED. 10, p. 429

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. 2017

  22. The effects of treatment failure generalize across different routes of drug administration

    Zunhammer, M., Ploner, M., Engelbrecht, C., Bock, J., Kessner, S. S. & Bingel, U., 07.06.2017, In: SCI TRANSL MED. 9, 393

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension

    Kossmann, S., Lagrange, J., Jäckel, S., Jurk, K., Ehlken, M., Schönfelder, T., Weihert, Y., Knorr, M., Brandt, M., Xia, N., Li, H., Daiber, A., Oelze, M., Reinhardt, C., Lackner, K., Gruber, A., Monia, B., Karbach, S. H., Walter, U., Ruggeri, Z. M., Renné, T., Ruf, W., Münzel, T. & Wenzel, P., 01.02.2017, In: SCI TRANSL MED. 9, 375

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. 2016

  25. Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation

    Danquah, W., Meyer-Schwesinger, C., Rissiek, B., Pinto, C., Serracant-Prat, A., Amadi, M., Iacenda, D., Knop, J-H., Hammel, A., Bergmann, P., Schwarz, N., Assunção, J., Rotthier, W., Haag, F., Tolosa, E., Bannas, P., Boué-Grabot, E., Magnus, T., Laeremans, T., Stortelers, C. & Nolte, F., 23.11.2016, In: SCI TRANSL MED. 8, 366, p. 366ra162

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells

    Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K-H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A. & Eschenhagen, T., 02.11.2016, In: SCI TRANSL MED. 8, 363, p. 363ra148

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Immunotherapy of non-Hodgkin's lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor-modified T cells

    Turtle, C. J., Hanafi, L-A., Berger, C., Hudecek, M., Pender, B., Robinson, E., Hawkins, R., Chaney, C., Cherian, S., Chen, X., Soma, L., Wood, B., Li, D., Heimfeld, S., Riddell, S. R. & Maloney, D. G., 07.09.2016, In: SCI TRANSL MED. 8, 355, p. 355ra116

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Comment on "Absence of sperm RNA elements correlates with idiopathic male infertility"

    Cappallo-Obermann, H. & Spiess, A-N., 24.08.2016, In: SCI TRANSL MED. 8, 353, p. 353tc1

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  29. A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

    Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancáková, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J., Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J-H., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, A., Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Müller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quirós, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sánchez, M-J., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., van der A, D. L., van der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Aponte, J. L., Butterworth, A. S., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, T., Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., Langenberg, C., McCarthy, M. I., Pankow, J. S., Pedersen, O., Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J., Waterworth, D. M. & CVD50 consortium, 01.06.2016, In: SCI TRANSL MED. 8, 341, p. 341ra76

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts

    Uluçkan, Ö., Jimenez, M., Karbach, S., Jeschke, A., Graña, O., Keller, J., Busse, B., Croxford, A. L., Finzel, S., Koenders, M., van den Berg, W., Schinke, T., Amling, M., Waisman, A., Schett, G. & Wagner, E. F., 16.03.2016, In: SCI TRANSL MED. 8, 330, p. 330ra37

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. 2014

  32. Hematogenous dissemination of glioblastoma multiforme

    Müller, C., Holtschmidt, J., Auer, M., Heitzer, E., Lamszus, K., Schulte, A., Matschke, J., Langer-Freitag, S., Gasch, C., Stoupiec, M., Mauermann, O., Peine, S., Glatzel, M., Speicher, M. R., Geigl, J. B., Westphal, M., Pantel, K. & Riethdorf, S., 30.07.2014, In: SCI TRANSL MED. 6, 247, p. 247ra101

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. IL-17 and GM-CSF expression are antagonistically regulated by human T helper cells

    Noster, R., Riedel, R., Mashreghi, M-F., Radbruch, H., Harms, L., Haftmann, C., Chang, H-D., Radbruch, A. & Zielinski, C. E., 18.06.2014, In: SCI TRANSL MED. 6, 241, p. 241ra80

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway

    Bozec, A., Zaiss, M. M., Kagwiria, R., Voll, R., Rauh, M., Chen, Z., Mueller-Schmucker, S., Kroczek, R. A., Heinzerling, L., Moser, M., Mellor, A. L., David, J-P. & Schett, G., 07.05.2014, In: SCI TRANSL MED. 6, 235, p. 235ra60

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk

    Larsson, M., Rayzman, V., Nolte, M. W., Nickel, K. F., Björkqvist, J., Jämsä, A., Hardy, M. P., Fries, M., Schmidbauer, S., Hedenqvist, P., Broomé, M., Pragst, I., Dickneite, G., Wilson, M. J., Nash, A. D., Panousis, C. & Renné, T., 05.02.2014, In: SCI TRANSL MED. 6, 222, p. 222ra17

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 2013

  37. Adenosine receptor antagonists including caffeine alter fetal brain development in mice

    Silva, C. G., Métin, C., Fazeli, W., Machado, N. J., Darmopil, S., Launay, P-S., Ghestem, A., Nesa, M-P., Bassot, E., Szabó, E., Baqi, Y., Müller, C. E., Tomé, A. R., Ivanov, A., Isbrandt, D., Zilberter, Y., Cunha, R. A., Esclapez, M. & Bernard, C., 07.08.2013, In: SCI TRANSL MED. 5, 197, p. 197ra104

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Vitamin D deficiency induces early signs of aging in human bone, increasing the risk of fracture

    Busse, B., Bale, H. A., Zimmermann, E. A., Panganiban, B., Barth, H. D., Carriero, A., Vettorazzi, E., Zustin, J., Hahn, M., Ager, J. W., Püschel, K., Amling, M. & Ritchie, R. O., 10.07.2013, In: SCI TRANSL MED. 5, 193, p. 193ra88

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Antigen-specific tolerance by autologous myelin peptide-coupled cells: a phase 1 trial in multiple sclerosis

    Lutterotti, A., Yousef, S., Sputtek, A., Stürner, K. H., Stellmann, J-P., Breiden, P., Reinhardt, S., Schulze, C., Bester, M., Heesen, C., Schippling, S., Miller, S. D., Sospedra, M. & Martin, R., 05.06.2013, In: SCI TRANSL MED. 5, 188, p. 188ra75

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. 2011

  41. Neutrophil-derived cathelicidin protects from neointimal hyperplasia

    Soehnlein, O., Wantha, S., Simsekyilmaz, S., Döring, Y., Megens, R. T. A., Mause, S. F., Drechsler, M., Smeets, R., Weinandy, S., Schreiber, F., Gries, T., Jockenhoevel, S., Möller, M., Vijayan, S., van Zandvoort, M. A. M. J., Agerberth, B., Pham, C. T., Gallo, R. L., Hackeng, T. M., Liehn, E. A., Zernecke, A., Klee, D. & Weber, C., 05.10.2011, In: SCI TRANSL MED. 3, 103, p. 103ra98

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. The effect of treatment expectation on drug efficacy: imaging the analgesic benefit of the opioid remifentanil

    Bingel, U., Wanigasekera, V., Wiech, K., Ni Mhuircheartaigh, R., Lee, M. C., Ploner, M. & Tracey, I., 16.02.2011, In: SCI TRANSL MED. 3, 70, p. 70ra14

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review