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CELL SIGNAL - Cellular signalling

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Publications

  1. 2023

  2. Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases

    Ehm, P. A. H., Linnebacher, M., Block, A., Rehbach, C. & Jücker, M., 08.2023, In: CELL SIGNAL. 108, p. 110720

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants

    Ehm, P., Nelson, N., Giehler, S., Schaks, M., Bettin, B., Kirchmair, J. & Jücker, M., 01.2023, In: CELL SIGNAL. 101, 110485.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2022

  5. Investigation of the function of the PI3-Kinase / AKT signaling pathway for leukemogenesis and therapy of acute childhood lymphoblastic leukemia (ALL)

    Ehm, P., Grottke, A., Bettin, B. & Jücker, M., 05.2022, In: CELL SIGNAL. 93, 110301.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. 2021

  7. Regulation of basal and norepinephrine-induced cAMP and ICa in hiPSC-cardiomyocytes: Effects of culture conditions and comparison to adult human atrial cardiomyocytes

    Iqbal, Z., Ismaili, D., Dolce, B., Petersen, J., Reichenspurner, H., Hansen, A., Kirchhof, P., Eschenhagen, T., Nikolaev, V. O., Molina, C. E. & Christ, T., 06.2021, In: CELL SIGNAL. 82, p. 109970

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Regulation of dual leucine zipper kinase activity through its interaction with calcineurin

    Duque Escobar, J., Kutschenko, A., Schroeder, S., Blume, R., Köster, K-A., Painer, C., Lemcke, T., Maison, W. & Oetjen, E., 2021, In: CELL SIGNAL. 82, p. 109953

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2019

  10. Analysis of the FLVR motif of SHIP1 and its importance for the protein stability of SH2 containing signaling proteins

    Ehm, P. A. H., Lange, F., Hentschel, C., Jepsen, A., Glück, M., Nelson, N., Bettin, B., de Bruyn Kops, C., Kirchmair, J., Nalaskowski, M. & Jücker, M., 11.2019, In: CELL SIGNAL. 63, p. 109380

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes

    Stathopoulou, K., Schobesberger, S., Bork, N. I., Sprenger, J. U., Perera, R. K., Sotoud, H., Geertz, B., David, J-P., Christ, T., Nikolaev, V. O. & Cuello, F., 11.2019, In: CELL SIGNAL. 63, p. 109362

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. 2018

  13. Amyloid precursor protein is required for in vitro platelet adhesion to amyloid peptides and potentiation of thrombus formation

    Visconte, C., Canino, J., Guidetti, G. F., Zarà, M., Seppi, C., Abubaker, A. A., Pula, G., Torti, M. & Canobbio, I., 12.2018, In: CELL SIGNAL. 52, p. 95-102 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Nuclear accumulation of SHIP1 mutants derived from AML patients leads to increased proliferation of leukemic cells

    Nalaskowski, M. M., Ehm, P., Rehbach, C., Nelson, N., Täger, M., Modest, K. & Jücker, M., 09.2018, In: CELL SIGNAL. 49, p. 87-94 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. 2016

  16. Treatment with MAPKAP2 (MK2) inhibitor and DNA methylation inhibitor, 5-aza dC, synergistically triggers apoptosis in hepatocellular carcinoma (HCC) via tristetraprolin (TTP)

    Tran, D. D. H., Koch, A., Allister, A., Saran, S., Ewald, F., Koch, M., Nashan, B. & Tamura, T., 12.2016, In: CELL SIGNAL. 28, 12, p. 1872-1880 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Extracellular-signal regulated kinase (Erk1/2), mitogen-activated protein kinase-activated protein kinase 2 (MK2) and tristetraprolin (TTP) comprehensively regulate injury-induced immediate early gene (IEG) response in in vitro liver organ culture

    Tran, D. D. H., Koch, A., Saran, S., Armbrecht, M., Ewald, F., Koch, M., Wahlicht, T., Wirth, D., Braun, A., Nashan, B., Gaestel, M. & Tamura, T., 05.2016, In: CELL SIGNAL. 28, 5, p. 438-47 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Distinct functions of the dual leucine zipper kinase depending on its subcellular localization

    Wallbach, M., Duque Escobar, J., Babaeikelishomi, R., Stahnke, M-J., Blume, R., Schröder, S., Kruegel, J., Maedler, K., Kluth, O., Kehlenbach, R. H., Miosge, N. & Oetjen, E., 04.2016, In: CELL SIGNAL. 28, 4, p. 272-83 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Inositol-1,4,5-trisphosphate-3-kinase-A controls morphology of hippocampal dendritic spines

    Köster, J-D., Leggewie, B., Blechner, C., Brandt, N., Fester, L., Rune, G., Schweizer, M., Kindler, S. & Windhorst, S., 01.2016, In: CELL SIGNAL. 28, 1, p. 83-90 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. 2015

  21. Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasion

    Nörz, D., Grottke, A., Bach, J., Herzberger, C., Hofmann, B. T., Nashan, B., Jücker, M. & Ewald, F., 11.2015, In: CELL SIGNAL. 27, 11, p. 2191-200 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: Identification of novel targets for concerted therapy concepts

    Kebenko, M., Drenckhan, A., Gros, S. J., Jücker, M., Grabinski, N., Ewald, F., Grottke, A., Schultze, A., Izbicki, J. R., Bokemeyer, C., Wellbrock, J. & Fiedler, W., 01.02.2015, In: CELL SIGNAL. 27, 2, p. 373-81 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. 2014

  24. Inhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinase

    Stahnke, M. J., Dickel, C., Schröder, S., Kaiser, D., Blume, R., Stein, R., Pouponnot, C. & Oetjen, E., 01.09.2014, In: CELL SIGNAL. 26, 9, p. 1792-1799

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. AKT3 regulates ErbB2, ErbB3 and estrogen receptor α expression and contributes to endocrine therapy resistance of ErbB2(+) breast tumor cells from Balb-neuT mice

    Grabinski, N., Möllmann, K., Milde-Langosch, K., Müller, V., Schumacher, U., Brandt, B., Pantel, K. & Jücker, M., 01.05.2014, In: CELL SIGNAL. 26, 5, p. 1021-9 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. 2013

  27. Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP--implications for CREB-dependent gene transcription.

    Heinrich, A., Heyde, V. D., Sophie, A., Böer, U., Phu, D. T. & Oetjen, E., 2013, In: CELL SIGNAL. 25, 1, p. 113-125 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. 2012

  29. Activation of PI3K/Akt signaling by n-terminal SH2 domain mutants of the p85α regulatory subunit of PI3K is enhanced by deletion of its c-terminal SH2 domain.

    Hofmann, B. T. & Jücker, M., 2012, In: CELL SIGNAL. 24, 10, p. 1950-1954 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Inositol-1,4,5-trisphosphate 3-kinase A regulates dendritic morphology and shapes synaptic Ca2+ transients.

    Windhorst, S., Minge, D., Bähring, R., Hüser, S., Schob, C., Blechner, C., Lin, H., Mayr, G. W. & Kindler, S., 2012, In: CELL SIGNAL. 24, 3, p. 750-757 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.

    Brauer, H., Strauss, J., Wegner, W., Müller-Tidow, C., Horstmann, M. & Jücker, M., 2012, In: CELL SIGNAL. 24, 11, p. 2095-2101 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. The inositol 5-phosphatase SHIP1 is a nucleo-cytoplasmic shuttling protein and enzymatically active in cell nuclei.

    Nalaskowski, M., Metzner, A., Brehm, M., Labiadh, S., Brauer, H., Grabinski, N., Mayr, G. W. & Jücker, M., 2012, In: CELL SIGNAL. 24, 3, p. 621-628 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. 2011

  34. Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells

    Grabinski, N., Bartkowiak, K., Grupp, K., Brandt, B., Pantel, K. & Jücker, M., 12.2011, In: CELL SIGNAL. 23, 12, p. 1952-1960 9 p., 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels

    Phu, D. T., Wallbach, M., Depatie, C., Fu, A., Screaton, R. A. & Oetjen, E., 02.2011, In: CELL SIGNAL. 23, 2, p. 344-53 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 2009

  37. Gastrointestinal growth factors and hormones have divergent effects on Akt activation.

    Berna, M., Tapia, J. A., Sancho, V., Berna-Thill, M., Pace, A., Hoffmann, K. M., Gonzalez-Fernandez, L. & Jensen, R. T., 2009, In: CELL SIGNAL. 21, 4, p. 622-638 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. 2008

  39. Endogenous Gas6 and Ca2+ -channel activation modulate phagocytosis by retinal pigment epithelium.

    Karl, M. O., Kroeger, W., Wimmers, S., Milenkovic, V. M., Valtink, M., Engelmann, K. & Strauss, O., 2008, In: CELL SIGNAL. 20, 6, p. 1159-1168 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. 2005

  41. The casein kinase 1 family: participation in multiple cellular processes in eukaryotes.

    Knippschild, U., Gocht, A., Wolff, S., Huber, N., Löhler, J. & Stöter, M., 2005, In: CELL SIGNAL. 17, 6, p. 675-689 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. 2003

  43. Analysis of subcellular calcium signals in T-lymphocytes.

    Kunerth, S., Mayr, G. W., Koch-Nolte, F. & Guse, A. H., 2003, In: CELL SIGNAL. 15, 8, p. 783-792 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. 2001

  45. Mechanisms involved in alpha6beta1-integrin-mediated Ca(2+) signalling.

    Schöttelndreier, H., Potter, B. V., Mayr, G. W. & Guse, A. H., 2001, In: CELL SIGNAL. 13, 12, p. 895-899 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. 1999

  47. Beta1-integrins mediate Ca2+-signalling and T cell spreading via divergent pathways.

    Schöttelndreier, H., Mayr, G. W. & Guse, A. H., 1999, In: CELL SIGNAL. 11, 8, p. 611-619 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review