BIOCHEM PHARMACOL - Biochemical pharmacology

Publications

  1. 2024
  2. Deletion of vascular thromboxane A2 receptors and its impact on angiotensin II-induced hypertension and atherosclerotic lesion formation in the aorta of Ldlr-deficient mice

    Braun, H., Hauke, M., Petermann, M., Eckenstaler, R., Ripperger, A., Schwedhelm, E., Ludwig-Kraus, B., Bernhard Kraus, F., Jalal Ahmed Shawon, M., Dubourg, V., Zernecke, A., Schreier, B., Gekle, M. & Benndorf, R. A., 01.2024, In: BIOCHEM PHARMACOL. 219, 115916.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. 2023
  4. Cryo-EM structures of actin binding proteins as tool for drug discovery

    Dahlstroem, C., Paraschiakos, T., Sun, H. & Windhorst, S., 08.2023, In: BIOCHEM PHARMACOL. 214, p. 115680

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  5. 2022
  6. Thromboxane A2 receptor activation via Gα13-RhoA/C-ROCK-LIMK2-dependent signal transduction inhibits angiogenic sprouting of human endothelial cells

    Eckenstaler, R., Ripperger, A., Hauke, M., Braun, H., Ergün, S., Schwedhelm, E. & Benndorf, R. A., 07.2022, In: BIOCHEM PHARMACOL. 201, 115069.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. DIAPH1 facilitates paclitaxel-mediated cytotoxicity of ovarian cancer cells

    Flat, W., Borowski, S., Paraschiakos, T., Blechner, C. & Windhorst, S., 03.2022, In: BIOCHEM PHARMACOL. 197, 114898.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. 2021
  9. Oncogenic activity and cellular functionality of melanoma associated antigen A3

    Schäfer, P., Paraschiakos, T. & Windhorst, S., 10.2021, In: BIOCHEM PHARMACOL. 192, 114700.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  10. Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy

    Smit, D. J., Pantel, K. & Jücker, M., 06.2021, In: BIOCHEM PHARMACOL. 188, p. 114589

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  11. Nanobodies as probes to investigate purinergic signaling

    Eggers, M., Rühl, F., Haag, F. & Koch-Nolte, F., 05.2021, In: BIOCHEM PHARMACOL. 187, 114394.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  12. 2020
  13. PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

    Marquard, F. E. & Jücker, M., 02.2020, In: BIOCHEM PHARMACOL. 172, p. 113729

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  14. 2019
  15. New options of cancer treatment employing InsP6

    Brehm, M. A. & Windhorst, S., 05.2019, In: BIOCHEM PHARMACOL. 163, p. 206-214 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  16. Inositol hexakisphosphate increases the size of platelet aggregates

    Brehm, M. A., Klemm, U., Rehbach, C., Erdmann, N., Kolšek, K., Lin, H., Aponte-Santamaría, C., Gräter, F., Rauch, B. H., Riley, A. M., Mayr, G. W., Potter, B. V. L. & Windhorst, S., 03.2019, In: BIOCHEM PHARMACOL. 161, p. 14-25 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. 2017
  18. Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) is frequently over-expressed and functions as an oncogene in several tumor types

    Windhorst, S., Song, K. & Gazdar, A. F., 01.08.2017, In: BIOCHEM PHARMACOL. 137, p. 1-9 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  19. 2016
  20. Heterodimerization with the β1 subunit directs the α2 subunit of nitric oxide-sensitive guanylyl cyclase to calcium-insensitive cell-cell contacts in HEK293 cells: Interaction with Lin7a

    Hochheiser, J., Haase, T., Busker, M., Sömmer, A., Kreienkamp, H-J. & Behrends, S., 15.12.2016, In: BIOCHEM PHARMACOL. 122, p. 23-32 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Internalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes

    Ismail, S., Gherardi, M-J., Froese, A., Zanoun, M., Gigoux, V., Clerc, P., Gaits-Iacovoni, F., Steyaert, J., Nikolaev, V. O. & Fourmy, D., 15.11.2016, In: BIOCHEM PHARMACOL. 120, p. 33-45 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Cannabinoid receptor 2 expression modulates Gβ1γ2 protein interaction with the activator of G protein signalling 2/dynein light chain protein Tctex-1

    Nagler, M., Palkowitsch, L., Rading, S., Moepps, B. & Karsak, M., 01.01.2016, In: BIOCHEM PHARMACOL. 99, p. 60-72 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. 2015
  24. Toxicity of teriflunomide in aryl hydrocarbon receptor deficient mice

    Redaelli, C., Gaffarogullari, E. C., Brune, M., Pilz, C., Becker, S., Sonner, J., Jäschke, A., Gröne, H-J., Wick, W., Platten, M. & Lanz, T. V., 01.12.2015, In: BIOCHEM PHARMACOL. 98, 3, p. 484-92 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells

    Schröder, D., Tödter, K., Gonzalez, B., Franco-Echevarría, E., Rohaly, G., Blechner, C., Lin, H., Mayr, G. W. & Windhorst, S., 15.07.2015, In: BIOCHEM PHARMACOL. 96, 2, p. 143-50 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. 2014
  27. Pharmacogenomics of cantharidin in tumor cells

    Kadioglu, O., Salehi-Kermani, N., Kelter, G., Schumacher, U., Fiebig, H-H., Greten, H. J. & Efferth, T., 01.02.2014, In: BIOCHEM PHARMACOL. 87, 3, p. 399-409 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. 2010
  29. New insights into tetrahydrobiopterin pharmacodynamics from Pah enu1/2, a mouse model for compound heterozygous tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency

    Lagler, F. B., Gersting, S. W., Zsifkovits, C., Steinbacher, A., Eichinger, A., Danecka, M. K., Staudigl, M., Fingerhut, R., Glossmann, H. & Muntau, A. C., 15.11.2010, In: BIOCHEM PHARMACOL. 80, 10, p. 1563-71 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. 2009
  31. Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.

    Ramer, R., Merkord, J., Rohde, H. & Hinz, B., 2009, In: BIOCHEM PHARMACOL.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Methylene blue and Alzheimer's disease.

    Oz, M., Lorke, D. & Petroianu, G. A., 2009, In: BIOCHEM PHARMACOL. 78, 8, p. 927-932 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. 2008
  34. Diadenosine polyphosphates Ap3A and Ap4A, but not Ap5A or Ap6A, induce proliferation of vascular smooth muscle cells.

    Bobbert, P., Schlüter, H., Schultheiss, H. P. & Reusch, H. P., 2008, In: BIOCHEM PHARMACOL. 75, 10, p. 1966-1973 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. 2006
  36. S100A8 and S100A9 in inflammation and cancer

    Gebhardt, C., Németh, J., Angel, P. & Hess, J., 30.11.2006, In: BIOCHEM PHARMACOL. 72, 11, p. 1622-31 10 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  37. 2004
  38. Inhibition of hyaluronan export from human fibroblasts by inhibitors of multidrug resistance transporters

    Prehm, P. & Schumacher, U., 01.10.2004, In: BIOCHEM PHARMACOL. 68, 7, p. 1401-10 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. 2003
  40. Important amino acids for the function of the human MT1 melatonin receptor.

    Kokkola, T., Foord, S. M., Watson, M-A., Vakkuri, O. & Laitinen, J. T., 2003, In: BIOCHEM PHARMACOL. 65, 9, p. 1463-1471 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. 2002
  42. Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells.

    Strohmeier, R., Roller, M., Sänger, N., Knecht, R. & Kuhl, H., 2002, In: BIOCHEM PHARMACOL. 64, 1, p. 99-107 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. 1998
  44. Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2

    Reber, U., Wüllner, U., Trepel, M., Baumgart, S. J., Seyfried, J., Klockgether, T., Dichgans, J. & Weller, M., 01.02.1998, In: BIOCHEM PHARMACOL. 55, 3, p. 349-59 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. 1993
  46. Metabolism of iron from (3,5,5-trimethylhexanoyl)ferrocene in rats. A dietary model for severe iron overload.

    Nielsen, P. & Heinrich, H. C., 1993, In: BIOCHEM PHARMACOL. 45, 2, p. 385-391 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. 1988
  48. Inhibition of amino acid uptake and incorporation into proteins in Friend erythroleukemia cells by the anthracycline antitumor antibiotic aclacinomycin A.

    Schaefer, A., Boldt, J., Westendorf, J., Steinheider, G. & Marquardt, H., 1988, In: BIOCHEM PHARMACOL. 37, 7, p. 1377-1382 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review