BIOCHEM PHARMACOL - Biochemical pharmacology
Publications
- 2024
Deletion of vascular thromboxane A2 receptors and its impact on angiotensin II-induced hypertension and atherosclerotic lesion formation in the aorta of Ldlr-deficient mice
Braun, H., Hauke, M., Petermann, M., Eckenstaler, R., Ripperger, A., Schwedhelm, E., Ludwig-Kraus, B., Bernhard Kraus, F., Jalal Ahmed Shawon, M., Dubourg, V., Zernecke, A., Schreier, B., Gekle, M. & Benndorf, R. A., 01.2024, In: BIOCHEM PHARMACOL. 219, 115916.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Cryo-EM structures of actin binding proteins as tool for drug discovery
Dahlstroem, C., Paraschiakos, T., Sun, H. & Windhorst, S., 08.2023, In: BIOCHEM PHARMACOL. 214, p. 115680Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2022
Thromboxane A2 receptor activation via Gα13-RhoA/C-ROCK-LIMK2-dependent signal transduction inhibits angiogenic sprouting of human endothelial cells
Eckenstaler, R., Ripperger, A., Hauke, M., Braun, H., Ergün, S., Schwedhelm, E. & Benndorf, R. A., 07.2022, In: BIOCHEM PHARMACOL. 201, 115069.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DIAPH1 facilitates paclitaxel-mediated cytotoxicity of ovarian cancer cells
Flat, W., Borowski, S., Paraschiakos, T., Blechner, C. & Windhorst, S., 03.2022, In: BIOCHEM PHARMACOL. 197, 114898.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Oncogenic activity and cellular functionality of melanoma associated antigen A3
Schäfer, P., Paraschiakos, T. & Windhorst, S., 10.2021, In: BIOCHEM PHARMACOL. 192, 114700.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Circulating tumor cells as a promising target for individualized drug susceptibility tests in cancer therapy
Smit, D. J., Pantel, K. & Jücker, M., 06.2021, In: BIOCHEM PHARMACOL. 188, p. 114589Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Nanobodies as probes to investigate purinergic signaling
Eggers, M., Rühl, F., Haag, F. & Koch-Nolte, F., 05.2021, In: BIOCHEM PHARMACOL. 187, 114394.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2020
PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer
Marquard, F. E. & Jücker, M., 02.2020, In: BIOCHEM PHARMACOL. 172, p. 113729Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2019
New options of cancer treatment employing InsP6
Brehm, M. A. & Windhorst, S., 05.2019, In: BIOCHEM PHARMACOL. 163, p. 206-214 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Inositol hexakisphosphate increases the size of platelet aggregates
Brehm, M. A., Klemm, U., Rehbach, C., Erdmann, N., Kolšek, K., Lin, H., Aponte-Santamaría, C., Gräter, F., Rauch, B. H., Riley, A. M., Mayr, G. W., Potter, B. V. L. & Windhorst, S., 03.2019, In: BIOCHEM PHARMACOL. 161, p. 14-25 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Inositol-1,4,5-trisphosphate 3-kinase-A (ITPKA) is frequently over-expressed and functions as an oncogene in several tumor types
Windhorst, S., Song, K. & Gazdar, A. F., 01.08.2017, In: BIOCHEM PHARMACOL. 137, p. 1-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2016
Heterodimerization with the β1 subunit directs the α2 subunit of nitric oxide-sensitive guanylyl cyclase to calcium-insensitive cell-cell contacts in HEK293 cells: Interaction with Lin7a
Hochheiser, J., Haase, T., Busker, M., Sömmer, A., Kreienkamp, H-J. & Behrends, S., 15.12.2016, In: BIOCHEM PHARMACOL. 122, p. 23-32 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Internalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes
Ismail, S., Gherardi, M-J., Froese, A., Zanoun, M., Gigoux, V., Clerc, P., Gaits-Iacovoni, F., Steyaert, J., Nikolaev, V. O. & Fourmy, D., 15.11.2016, In: BIOCHEM PHARMACOL. 120, p. 33-45 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cannabinoid receptor 2 expression modulates Gβ1γ2 protein interaction with the activator of G protein signalling 2/dynein light chain protein Tctex-1
Nagler, M., Palkowitsch, L., Rading, S., Moepps, B. & Karsak, M., 01.01.2016, In: BIOCHEM PHARMACOL. 99, p. 60-72 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Toxicity of teriflunomide in aryl hydrocarbon receptor deficient mice
Redaelli, C., Gaffarogullari, E. C., Brune, M., Pilz, C., Becker, S., Sonner, J., Jäschke, A., Gröne, H-J., Wick, W., Platten, M. & Lanz, T. V., 01.12.2015, In: BIOCHEM PHARMACOL. 98, 3, p. 484-92 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells
Schröder, D., Tödter, K., Gonzalez, B., Franco-Echevarría, E., Rohaly, G., Blechner, C., Lin, H., Mayr, G. W. & Windhorst, S., 15.07.2015, In: BIOCHEM PHARMACOL. 96, 2, p. 143-50 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Pharmacogenomics of cantharidin in tumor cells
Kadioglu, O., Salehi-Kermani, N., Kelter, G., Schumacher, U., Fiebig, H-H., Greten, H. J. & Efferth, T., 01.02.2014, In: BIOCHEM PHARMACOL. 87, 3, p. 399-409 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
New insights into tetrahydrobiopterin pharmacodynamics from Pah enu1/2, a mouse model for compound heterozygous tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency
Lagler, F. B., Gersting, S. W., Zsifkovits, C., Steinbacher, A., Eichinger, A., Danecka, M. K., Staudigl, M., Fingerhut, R., Glossmann, H. & Muntau, A. C., 15.11.2010, In: BIOCHEM PHARMACOL. 80, 10, p. 1563-71 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1.
Ramer, R., Merkord, J., Rohde, H. & Hinz, B., 2009, In: BIOCHEM PHARMACOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Methylene blue and Alzheimer's disease.
Oz, M., Lorke, D. & Petroianu, G. A., 2009, In: BIOCHEM PHARMACOL. 78, 8, p. 927-932 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Diadenosine polyphosphates Ap3A and Ap4A, but not Ap5A or Ap6A, induce proliferation of vascular smooth muscle cells.
Bobbert, P., Schlüter, H., Schultheiss, H. P. & Reusch, H. P., 2008, In: BIOCHEM PHARMACOL. 75, 10, p. 1966-1973 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
S100A8 and S100A9 in inflammation and cancer
Gebhardt, C., Németh, J., Angel, P. & Hess, J., 30.11.2006, In: BIOCHEM PHARMACOL. 72, 11, p. 1622-31 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2004
Inhibition of hyaluronan export from human fibroblasts by inhibitors of multidrug resistance transporters
Prehm, P. & Schumacher, U., 01.10.2004, In: BIOCHEM PHARMACOL. 68, 7, p. 1401-10 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Important amino acids for the function of the human MT1 melatonin receptor.
Kokkola, T., Foord, S. M., Watson, M-A., Vakkuri, O. & Laitinen, J. T., 2003, In: BIOCHEM PHARMACOL. 65, 9, p. 1463-1471 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells.
Strohmeier, R., Roller, M., Sänger, N., Knecht, R. & Kuhl, H., 2002, In: BIOCHEM PHARMACOL. 64, 1, p. 99-107 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1998
Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2
Reber, U., Wüllner, U., Trepel, M., Baumgart, S. J., Seyfried, J., Klockgether, T., Dichgans, J. & Weller, M., 01.02.1998, In: BIOCHEM PHARMACOL. 55, 3, p. 349-59 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1993
Metabolism of iron from (3,5,5-trimethylhexanoyl)ferrocene in rats. A dietary model for severe iron overload.
Nielsen, P. & Heinrich, H. C., 1993, In: BIOCHEM PHARMACOL. 45, 2, p. 385-391 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1988
Inhibition of amino acid uptake and incorporation into proteins in Friend erythroleukemia cells by the anthracycline antitumor antibiotic aclacinomycin A.
Schaefer, A., Boldt, J., Westendorf, J., Steinheider, G. & Marquardt, H., 1988, In: BIOCHEM PHARMACOL. 37, 7, p. 1377-1382 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review