ANTIMICROB AGENTS CH - Antimicrobial agents and chemotherapy
Publications
- 2023
Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus
Van, N., Degefu, Y. N., Leus, P. A., Larkins-Ford, J., Klickstein, J., Maurer, F. P., Stone, D., Poonawala, H., Thorpe, C. M., Smith, T. C. & Aldridge, B. B., 18.07.2023, In: ANTIMICROB AGENTS CH. 67, 7, p. e00090-23Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages
Sake, S. M., Kosch, C., Blockus, S., Haid, S., Gunesch, A. P., Zhang, X., Friesland, M., Trummer, S. B., Grethe, C., Kühnel, A., Rückert, J., Duprex, W. P., Huang, J., Rameix-Welti, M-A., Empting, M., Fischer, N., Hirsch, A. K. H., Schulz, T. F. & Pietschmann, T., 20.12.2022, In: ANTIMICROB AGENTS CH. 66, 12, e0103222.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pharmacokinetics of Nirmatrelvir and Ritonavir in COVID-19 Patients with End-Stage Renal Disease on Intermittent Hemodialysis
Lingscheid, T., Kinzig, M., Krüger, A., Müller, N., Bölke, G., Tober-Lau, P., Münn, F., Kriedemann, H., Witzenrath, M., Sander, L. E., Sörgel, F. & Kurth, F., 15.11.2022, In: ANTIMICROB AGENTS CH. 66, 11, e0122922.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Impact of Dose, Duration, and Immune Status on Efficacy of Ultrashort Telacebec Regimens in Mouse Models of Buruli Ulcer
Komm, O., Almeida, D. V., Converse, P. J., Omansen, T. F. & Nuermberger, E. L., 18.10.2021, In: ANTIMICROB AGENTS CH. 65, 11, e0141821.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Telacebec for Ultrashort Treatment of Buruli Ulcer in a Mouse Model
Almeida, D. V., Converse, P. J., Omansen, T. F., Tyagi, S., Tasneen, R., Kim, J. & Nuermberger, E. L., 21.05.2020, In: ANTIMICROB AGENTS CH. 64, 6, p. e00259-20Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Oxazolidinones Can Replace Clarithromycin in Combination with Rifampin in a Mouse Model of Buruli Ulcer
Almeida, D. V., Omansen, T. F., Li, S-Y., Lee, J., Grosset, J. H., Converse, P. J. & Nuermberger, E. L., 03.2019, In: ANTIMICROB AGENTS CH. 63, 3, p. e02171-18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of Mycobacterium ulcerans Disease
Omansen, T. F., Almeida, D., Converse, P. J., Li, S-Y., Lee, J., Stienstra, Y., van der Werf, T., Grosset, J. H. & Nuermberger, E. L., 02.2019, In: ANTIMICROB AGENTS CH. 63, 2, p. e01478-18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon
Ramharter, M., Schwab, M., Mombo-Ngoma, G., Zoleko Manego, R., Akerey-Diop, D., Basra, A., Mackanga, J-R., Würbel, H., Wojtyniak, J-G., Gonzalez, R., Hofmann, U., Geditz, M., Matsiegui, P-B., Kremsner, P. G., Menendez, C., Kerb, R. & Lehr, T., 02.2019, In: ANTIMICROB AGENTS CH. 63, 2, p. e01113-18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum
Müller, C., Fietz, C., Koehler, P., Sibley, G., Nforbugwe, A. C. A., Streichert, T. & Wiesen, M. H. J., 11.2018, In: ANTIMICROB AGENTS CH. 62, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of Clofazimine Dosing on Treatment Shortening of the First-Line Regimen in a Mouse Model of Tuberculosis
Ammerman, N. C., Swanson, R. V., Bautista, E. M., Almeida, D. V., Saini, V., Omansen, T. F., Guo, H., Chang, Y. S., Li, S-Y., Tapley, A., Tasneen, R., Tyagi, S., Betoudji, F., Moodley, C., Ngcobo, B., Pillay, L., Bester, L. A., Singh, S. D., Chaisson, R. E., Nuermberger, E. & Grosset, J. H., 07.2018, In: ANTIMICROB AGENTS CH. 62, 7, p. e00636-18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prospective Clinical Trial Assessing Species-Specific Efficacy of Artemether-Lumefantrine for the Treatment of Plasmodium malariae, Plasmodium ovale, and Mixed Plasmodium Malaria in Gabon
Groger, M., Veletzky, L., Lalremruata, A., Cattaneo, C., Mischlinger, J., Zoleko-Manego, R., Endamne, L., Klicpera, A., Kim, J., Nguyen, T., Flohr, L., Remppis, J., Matsiegui, P-B., Adegnika, A. A., Agnandji, S. T., Kremsner, P. G., Mordmüller, B., Mombo-Ngoma, G. & Ramharter, M., 03.2018, In: ANTIMICROB AGENTS CH. 62, 3, p. e01758-17Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Lack of antimicrobial bactericidal activity in Mycobacterium abscessus
Maurer, F. P., 07.2014, In: ANTIMICROB AGENTS CH. 58, 7, p. 3828-36 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pharmacokinetics of ganciclovir during continuous venovenous hemodiafiltration in critically ill patients
Horvatits, T., Kitzberger, R., Drolz, A., Zauner, C., Jäger, W., Böhmdorfer, M., Kraff, S., Fritsch, A., Thalhammer, F., Fuhrmann, V. & Schenk, P., 01.01.2014, In: ANTIMICROB AGENTS CH. 58, 1, p. 94-101 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Antiviral effect, safety, and pharmacokinetics of five-day oral administration of Deleobuvir (BI 207127), an investigational hepatitis C virus RNA polymerase inhibitor, in patients with chronic hepatitis C
Larrey, D., Lohse, A. W., Trepo, C., Bronowicki, J-P., Arastéh, K., Bourlière, M., Calleja, J. L., Stern, J. O., Nehmiz, G., Abdallah, N., Berger, K. L., Marquis, M., Steffgen, J., Kukolj, G. & BI 207127 Study Group, 01.10.2013, In: ANTIMICROB AGENTS CH. 57, 10, p. 4727-35 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
cyp51A-Based mechanisms of Aspergillus fumigatus azole drug resistance present in clinical samples from Germany
Bader, O., Weig, M., Reichard, U., Lugert, R., Kuhns, M., Christner, M., Held, J., Peter, S., Schumacher, U., Buchheidt, D., Tintelnot, K., Groß, U. & MykoLabNet-D Partners, 01.08.2013, In: ANTIMICROB AGENTS CH. 57, 8, p. 3513-7 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Microbiological analysis of a prospective, randomized, double-blind trial comparing moxifloxacin and clindamycin in the treatment of odontogenic infiltrates and abscesses.
Sobottka, I., Wegscheider, K., Balzer, O., Böger, R., Hallier, O., Giersdorf, I., Streichert, T., Haddad, M., Platzer, U. & Cachovan, G., 2012, In: ANTIMICROB AGENTS CH. 56, 5, p. 2565-2569 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Diphenylpyrazole-derived compounds increase survival time of mice after prion infection
Leidel, F., Eiden, M., Geissen, M., Kretzschmar, H. A., Giese, A., Hirschberger, T., Tavan, P., Schätzl, H. M. & Groschup, M. H., 10.2011, In: ANTIMICROB AGENTS CH. 55, 10, p. 4774-4781 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparative efficacy and safety of moxifloxacin and clindamycin in the treatment of odontogenic abscesses and inflammatory infiltrates: a phase II, double-blind, randomized trial.
Cachovan, G., Böger, R., Giersdorf, I., Hallier, O., Streichert, T., Haddad, M., Platzer, U., Schön, G., Wegscheider, K. & Sobottka, I., 2011, In: ANTIMICROB AGENTS CH. 55, 3, p. 1142-1147 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment.
Burhenne, J., Matthée, A-K., Pasáková, I., Röder, C., Heinrich, T., Haefeli, W. E., Mikus, G. & Weiss, J., 2010, In: ANTIMICROB AGENTS CH. 54, 10, p. 4185-4191 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ramR mutations in clinical isolates of Klebsiella pneumoniae with reduced susceptibility to tigecycline.
Hentschke, M., Wolters, M., Sobottka, I., Rohde, H. & Aepfelbacher, M., 2010, In: ANTIMICROB AGENTS CH. 54, 6, p. 2720-2723 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Combined ramR mutation and presence of a Tn1721-associated tet(A) variant in a clinical isolate of Salmonella enterica Serovar Hadar resistant to Tigecycline.
Hentschke, M., Christner, M., Sobottka, I., Aepfelbacher, M. & Rohde, H., 2009, In: ANTIMICROB AGENTS CH.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria
Kobbe, R., Schreiber, N., May, J. & Jacobs, T., 01.04.2008, In: ANTIMICROB AGENTS CH. 52, 4, p. 1583-4 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Intermittent preventive treatment in infants as a means of malaria control: a randomized, double-blind, placebo-controlled trial in northern Ghana.
Mockenhaupt, F. P., Reither, K., Zanger, P., Roepcke, F., Danquah, I., Saad, E., Ziniel, P., Dzisi, S. Y., Frempong, M., Agana-Nsiire, P., Amoo-Sakyi, F., Otchwemah, R., Cramer, J., Anemana, S. D., Dietz, E. & Bienzle, U., 2007, In: ANTIMICROB AGENTS CH. 51, 9, p. 3273-3281 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Large-scale surveillance of Plasmodium falciparum crt(K76T) in northern Ghana.
Ehrhardt, S., Eggelte, T. A., Kaiser, S., Adjei, L., Burchard, G-D., Anemana, S. D., Bienzle, U. & Mockenhaupt, F. P., 2007, In: ANTIMICROB AGENTS CH. 51, 9, p. 3407-3409 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Strong and selective inhibitors of hepatitis B virus replication among novel N4-hydroxy- and 5-methyl-beta-L-deoxycytidine analogues.
Matthes, E., Funk, A., Krahn, I., Gaertner, K., von Janta-Lipinski, M., Lin, L., Will, H. & Sirma, H., 2007, In: ANTIMICROB AGENTS CH. 51, 7, p. 2523-2530 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2005
mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis
Knobloch, J. K-M., Jäger, S., Huck, J., Horstkotte, M. A. & Mack, D., 03.2005, In: ANTIMICROB AGENTS CH. 49, 3, p. 1216-9 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Characterization of imidazo[4,5-d]pyridazine nucleosides as modulators of unwinding reaction mediated by West Nile virus nucleoside triphosphatase/helicase: evidence for activity on the level of substrate and/or enzyme.
Borowski, P., Lang, M., Haag, A., Schmitz, H., Choe, J., Huan-Ming, C. & Hosmane Ramachandra, S., 2002, In: ANTIMICROB AGENTS CH. 46, 5, p. 1231-1239 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differential expression of methicillin resistance by different biofilm-negative Staphylococcus epidermidis transposon mutant classes.
Mack, D., Sabottke, A., Dobinsky, S., Rohde, H., Horstkotte, M. A. & Knobloch, J. K-M., 2002, In: ANTIMICROB AGENTS CH. 46, 1, p. 178-183 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vitro activity of moxifloxacin against bacteria isolated from odontogenic abscesses.
Sobottka, I., Cachovan, G., Stürenburg, E., Ahlers, O., Laufs, R., Platzer, U. & Mack, D., 2002, In: ANTIMICROB AGENTS CH. 46, 12, p. 4019-4021 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
Concentrations of chloroquine and malaria parasites in blood in Nigerian children.
Mockenhaupt, F. P., May, J., Bergqvist, Y., Ademowo, O. G., Olumese, P. E., Falusi, A. G., Großterlinden, L. G., Meyer, C. G. & Bienzle, U., 2000, In: ANTIMICROB AGENTS CH. 44, 4, p. 835-839 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1998
Immunomodulating properties of the antibiotic novobiocin in human monocytes.
Lührmann, A., Thölke, J., Behn, I., Schumann, J., Tiegs, G. & Hauschildt, S., 1998, In: ANTIMICROB AGENTS CH. 42, 8, p. 1911-1916 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review