Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.
Beteiligte Einrichtungen
Abstract
Pathogenic yersiniae inject several effector proteins (Yops) into host cells, which subverts immune functions and enables the bacteria to survive within the host organism. YopM, whose deletion in enteropathogenic yersiniae results in a dramatic loss of virulence, has previously been shown to form a complex with and activate the multifunctional kinases PKN2 and RSK1 in transfected cells.
Bibliografische Daten
| Originalsprache | Deutsch |
|---|---|
| Aufsatznummer | 10 |
| ISSN | 1932-6203 |
| DOIs | |
| Status | Veröffentlicht - 2010 |
| pubmed | 20957203 |
|---|
