Treating progressive multifocal leukoencephalopathy with interleukin 7 and vaccination with JC virus capsid protein VP1
Standard
Treating progressive multifocal leukoencephalopathy with interleukin 7 and vaccination with JC virus capsid protein VP1. / Sospedra, Mireia; Schippling, Sven; Yousef, Sara; Jelcic, Ilijas; Bofill-Mas, Silvia; Planas, Raquel; Stellmann, Jan-Patrick; Demina, Viktoria; Cinque, Paola; Garcea, Robert; Croughs, Therese; Girones, Rosina; Martin, Roland.
in: CLIN INFECT DIS, Jahrgang 59, Nr. 11, 01.12.2014, S. 1588-92.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Treating progressive multifocal leukoencephalopathy with interleukin 7 and vaccination with JC virus capsid protein VP1
AU - Sospedra, Mireia
AU - Schippling, Sven
AU - Yousef, Sara
AU - Jelcic, Ilijas
AU - Bofill-Mas, Silvia
AU - Planas, Raquel
AU - Stellmann, Jan-Patrick
AU - Demina, Viktoria
AU - Cinque, Paola
AU - Garcea, Robert
AU - Croughs, Therese
AU - Girones, Rosina
AU - Martin, Roland
N1 - © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Progressive multifocal leukoencephalopathy is a currently untreatable infection of the brain. Here, we demonstrate in 2 patients that treatment with interleukin 7, JC polyomavirus (JCV) capsid protein VP1, and a Toll-like receptor 7 agonist used as adjuvant, was well tolerated, and showed a very favorable safety profile and unexpected efficacy that warrant further investigation.
AB - Progressive multifocal leukoencephalopathy is a currently untreatable infection of the brain. Here, we demonstrate in 2 patients that treatment with interleukin 7, JC polyomavirus (JCV) capsid protein VP1, and a Toll-like receptor 7 agonist used as adjuvant, was well tolerated, and showed a very favorable safety profile and unexpected efficacy that warrant further investigation.
U2 - 10.1093/cid/ciu682
DO - 10.1093/cid/ciu682
M3 - SCORING: Journal article
C2 - 25214510
VL - 59
SP - 1588
EP - 1592
JO - CLIN INFECT DIS
JF - CLIN INFECT DIS
SN - 1058-4838
IS - 11
ER -