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Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis

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Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis. / Schluter, Matthias; Fuh, Manka M; Maier, Stephanie; Otte, Christoph; Kiani, Parnian; Hansen, Nils-Owe; Dwayne Miller, R J; Schluter, Hartmut; Schlaefer, Alexander.

in: Conf Proc IEEE Eng Med Biol Soc, Jahrgang 2019, 07.2019, S. 158-161.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schluter, M, Fuh, MM, Maier, S, Otte, C, Kiani, P, Hansen, N-O, Dwayne Miller, RJ, Schluter, H & Schlaefer, A 2019, 'Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis', Conf Proc IEEE Eng Med Biol Soc, Jg. 2019, S. 158-161. https://doi.org/10.1109/EMBC.2019.8856808

APA

Schluter, M., Fuh, M. M., Maier, S., Otte, C., Kiani, P., Hansen, N-O., Dwayne Miller, R. J., Schluter, H., & Schlaefer, A. (2019). Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis. Conf Proc IEEE Eng Med Biol Soc, 2019, 158-161. https://doi.org/10.1109/EMBC.2019.8856808

Vancouver

Schluter M, Fuh MM, Maier S, Otte C, Kiani P, Hansen N-O et al. Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis. Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:158-161. https://doi.org/10.1109/EMBC.2019.8856808

Bibtex

@article{e2e61ffc9bf04c188f1fea59a537d8e7,
title = "Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis",
abstract = "Medical lasers are commonly used in interventions to ablate tumor tissue. Recently, the picosecond infrared laser has been introduced, which greatly decreases damaging of surrounding healthy tissue. Further, its ablation plume contains intact biomolecules which can be collected and analyzed by mass spectrometry. This allows for a specific chracterization of the tissue. For a precise treatment, however, a suitable guidance is needed. Further, spatial information is required if the tissue is to be characterized at different parts in the ablated area. Therefore, we propose a system which employs optical coherence tomography as the guiding imaging modality. We describe a prototypical system which provides automatic ablation of areas defined in the image data. For this purpose, we use a calibration with a robot which drives the laser fiber and collects the arising plume. We demonstrate our system on porcine tissue samples.",
author = "Matthias Schluter and Fuh, {Manka M} and Stephanie Maier and Christoph Otte and Parnian Kiani and Nils-Owe Hansen and {Dwayne Miller}, {R J} and Hartmut Schluter and Alexander Schlaefer",
year = "2019",
month = jul,
doi = "10.1109/EMBC.2019.8856808",
language = "English",
volume = "2019",
pages = "158--161",

}

RIS

TY - JOUR

T1 - Towards OCT-Navigated Tissue Ablation with a Picosecond Infrared Laser (PIRL) and Mass-Spectrometric Analysis

AU - Schluter, Matthias

AU - Fuh, Manka M

AU - Maier, Stephanie

AU - Otte, Christoph

AU - Kiani, Parnian

AU - Hansen, Nils-Owe

AU - Dwayne Miller, R J

AU - Schluter, Hartmut

AU - Schlaefer, Alexander

PY - 2019/7

Y1 - 2019/7

N2 - Medical lasers are commonly used in interventions to ablate tumor tissue. Recently, the picosecond infrared laser has been introduced, which greatly decreases damaging of surrounding healthy tissue. Further, its ablation plume contains intact biomolecules which can be collected and analyzed by mass spectrometry. This allows for a specific chracterization of the tissue. For a precise treatment, however, a suitable guidance is needed. Further, spatial information is required if the tissue is to be characterized at different parts in the ablated area. Therefore, we propose a system which employs optical coherence tomography as the guiding imaging modality. We describe a prototypical system which provides automatic ablation of areas defined in the image data. For this purpose, we use a calibration with a robot which drives the laser fiber and collects the arising plume. We demonstrate our system on porcine tissue samples.

AB - Medical lasers are commonly used in interventions to ablate tumor tissue. Recently, the picosecond infrared laser has been introduced, which greatly decreases damaging of surrounding healthy tissue. Further, its ablation plume contains intact biomolecules which can be collected and analyzed by mass spectrometry. This allows for a specific chracterization of the tissue. For a precise treatment, however, a suitable guidance is needed. Further, spatial information is required if the tissue is to be characterized at different parts in the ablated area. Therefore, we propose a system which employs optical coherence tomography as the guiding imaging modality. We describe a prototypical system which provides automatic ablation of areas defined in the image data. For this purpose, we use a calibration with a robot which drives the laser fiber and collects the arising plume. We demonstrate our system on porcine tissue samples.

U2 - 10.1109/EMBC.2019.8856808

DO - 10.1109/EMBC.2019.8856808

M3 - SCORING: Journal article

C2 - 31945868

VL - 2019

SP - 158

EP - 161

ER -