TNF and bone

Jean-Pierre David; Georg Schett

doi:10.1159/000289202

TNF and bone

Standard

TNF and bone. / David, Jean-Pierre; Schett, Georg.

in: Current directions in autoimmunity, Jahrgang 11, 01.01.2010, S. 135-44.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung

Harvard

David, J-P & Schett, G 2010, 'TNF and bone', Current directions in autoimmunity, Jg. 11, S. 135-44. https://doi.org/10.1159/000289202

APA

David, J-P., & Schett, G. (2010). TNF and bone. Current directions in autoimmunity, 11, 135-44. https://doi.org/10.1159/000289202

Vancouver

David J-P, Schett G. TNF and bone. Current directions in autoimmunity. 2010 Jan 1;11:135-44. https://doi.org/10.1159/000289202

Bibtex

@article{8e801dac3a92486581bb1731003b2b9f,

title = "TNF and bone",

abstract = "Bone is subject to permanent remodeling during development and through life. This activity is essential for (a) proper shaping and growth of each bone during development; (b) maintenance of bone mass as well as structural integrity of the micro architecture of bone through adult life, and (c) tissue repair needed for healing of fracture as well as of micro-damage. In addition to genetically linked rare developmental diseases, disturbances in bone remodeling are causing common bone pathologies, which severely impair the quality of life of patients. Among them are postmenopausal osteoporosis and local as well as systemic bone loss observed in chronic inflammatory diseases such as rheumatoid arthritis. The role of TNF-alpha in mediating bone remodeling will be presented and discussed in this chapter.",

keywords = "Animals, Bone Remodeling, Bone and Bones, Cell Differentiation, Humans, Mice, Models, Biological, Osteoblasts, Osteoclasts, Receptors, Tumor Necrosis Factor, Tumor Necrosis Factor-alpha",

author = "Jean-Pierre David and Georg Schett",

year = "2010",

month = jan,

day = "1",

doi = "10.1159/000289202",

language = "English",

volume = "11",

pages = "135--44",

}

RIS

TY - JOUR

T1 - TNF and bone

AU - David, Jean-Pierre

AU - Schett, Georg

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Bone is subject to permanent remodeling during development and through life. This activity is essential for (a) proper shaping and growth of each bone during development; (b) maintenance of bone mass as well as structural integrity of the micro architecture of bone through adult life, and (c) tissue repair needed for healing of fracture as well as of micro-damage. In addition to genetically linked rare developmental diseases, disturbances in bone remodeling are causing common bone pathologies, which severely impair the quality of life of patients. Among them are postmenopausal osteoporosis and local as well as systemic bone loss observed in chronic inflammatory diseases such as rheumatoid arthritis. The role of TNF-alpha in mediating bone remodeling will be presented and discussed in this chapter.

AB - Bone is subject to permanent remodeling during development and through life. This activity is essential for (a) proper shaping and growth of each bone during development; (b) maintenance of bone mass as well as structural integrity of the micro architecture of bone through adult life, and (c) tissue repair needed for healing of fracture as well as of micro-damage. In addition to genetically linked rare developmental diseases, disturbances in bone remodeling are causing common bone pathologies, which severely impair the quality of life of patients. Among them are postmenopausal osteoporosis and local as well as systemic bone loss observed in chronic inflammatory diseases such as rheumatoid arthritis. The role of TNF-alpha in mediating bone remodeling will be presented and discussed in this chapter.

KW - Animals

KW - Bone Remodeling

KW - Bone and Bones

KW - Cell Differentiation

KW - Humans

KW - Mice

KW - Models, Biological

KW - Osteoblasts

KW - Osteoclasts

KW - Receptors, Tumor Necrosis Factor

KW - Tumor Necrosis Factor-alpha

U2 - 10.1159/000289202

DO - 10.1159/000289202

M3 - SCORING: Journal article

C2 - 20173392

VL - 11

SP - 135

EP - 144

ER -