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Tissue-resident immunity in the lung

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Tissue-resident immunity in the lung : a first-line defense at the environmental interface. / Zazara, Dimitra E; Belios, Ioannis; Lücke, Jöran; Zhang, Tao; Giannou, Anastasios D.

in: SEMIN IMMUNOPATHOL, Jahrgang 44, Nr. 6, 11.2022, S. 827-854.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Zazara, DE, Belios, I, Lücke, J, Zhang, T & Giannou, AD 2022, 'Tissue-resident immunity in the lung: a first-line defense at the environmental interface', SEMIN IMMUNOPATHOL, Jg. 44, Nr. 6, S. 827-854. https://doi.org/10.1007/s00281-022-00964-2

APA

Zazara, D. E., Belios, I., Lücke, J., Zhang, T., & Giannou, A. D. (2022). Tissue-resident immunity in the lung: a first-line defense at the environmental interface. SEMIN IMMUNOPATHOL, 44(6), 827-854. https://doi.org/10.1007/s00281-022-00964-2

Vancouver

Zazara DE, Belios I, Lücke J, Zhang T, Giannou AD. Tissue-resident immunity in the lung: a first-line defense at the environmental interface. SEMIN IMMUNOPATHOL. 2022 Nov;44(6):827-854. https://doi.org/10.1007/s00281-022-00964-2

Bibtex

@article{186d7cf0d4744f82bbd5ccee0fb4c9d0,
title = "Tissue-resident immunity in the lung: a first-line defense at the environmental interface",
abstract = "The lung is a vital organ that incessantly faces external environmental challenges. Its homeostasis and unimpeded vital function are ensured by the respiratory epithelium working hand in hand with an intricate fine-tuned tissue-resident immune cell network. Lung tissue-resident immune cells span across the innate and adaptive immunity and protect from infectious agents but can also prove to be pathogenic if dysregulated. Here, we review the innate and adaptive immune cell subtypes comprising lung-resident immunity and discuss their ontogeny and role in distinct respiratory diseases. An improved understanding of the role of lung-resident immunity and how its function is dysregulated under pathological conditions can shed light on the pathogenesis of respiratory diseases.",
keywords = "Humans, Immunity, Innate, Lung, Adaptive Immunity, Homeostasis",
author = "Zazara, {Dimitra E} and Ioannis Belios and J{\"o}ran L{\"u}cke and Tao Zhang and Giannou, {Anastasios D}",
note = "{\textcopyright} 2022. The Author(s).",
year = "2022",
month = nov,
doi = "10.1007/s00281-022-00964-2",
language = "English",
volume = "44",
pages = "827--854",
journal = "SEMIN IMMUNOPATHOL",
issn = "1863-2297",
publisher = "Springer",
number = "6",

}

RIS

TY - JOUR

T1 - Tissue-resident immunity in the lung

T2 - a first-line defense at the environmental interface

AU - Zazara, Dimitra E

AU - Belios, Ioannis

AU - Lücke, Jöran

AU - Zhang, Tao

AU - Giannou, Anastasios D

N1 - © 2022. The Author(s).

PY - 2022/11

Y1 - 2022/11

N2 - The lung is a vital organ that incessantly faces external environmental challenges. Its homeostasis and unimpeded vital function are ensured by the respiratory epithelium working hand in hand with an intricate fine-tuned tissue-resident immune cell network. Lung tissue-resident immune cells span across the innate and adaptive immunity and protect from infectious agents but can also prove to be pathogenic if dysregulated. Here, we review the innate and adaptive immune cell subtypes comprising lung-resident immunity and discuss their ontogeny and role in distinct respiratory diseases. An improved understanding of the role of lung-resident immunity and how its function is dysregulated under pathological conditions can shed light on the pathogenesis of respiratory diseases.

AB - The lung is a vital organ that incessantly faces external environmental challenges. Its homeostasis and unimpeded vital function are ensured by the respiratory epithelium working hand in hand with an intricate fine-tuned tissue-resident immune cell network. Lung tissue-resident immune cells span across the innate and adaptive immunity and protect from infectious agents but can also prove to be pathogenic if dysregulated. Here, we review the innate and adaptive immune cell subtypes comprising lung-resident immunity and discuss their ontogeny and role in distinct respiratory diseases. An improved understanding of the role of lung-resident immunity and how its function is dysregulated under pathological conditions can shed light on the pathogenesis of respiratory diseases.

KW - Humans

KW - Immunity, Innate

KW - Lung

KW - Adaptive Immunity

KW - Homeostasis

U2 - 10.1007/s00281-022-00964-2

DO - 10.1007/s00281-022-00964-2

M3 - SCORING: Review article

C2 - 36305904

VL - 44

SP - 827

EP - 854

JO - SEMIN IMMUNOPATHOL

JF - SEMIN IMMUNOPATHOL

SN - 1863-2297

IS - 6

ER -