Tight junctions: is there a role in dermatology?

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Tight junctions: is there a role in dermatology? / Kirschner, Nina; Bohner, Claudia; Rachow, Susanne; Brandner, Johanna.

in: ARCH DERMATOL RES, Jahrgang 302, Nr. 7, 7, 2010, S. 483-493.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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Kirschner N, Bohner C, Rachow S, Brandner J. Tight junctions: is there a role in dermatology? ARCH DERMATOL RES. 2010;302(7):483-493. 7.

Bibtex

@article{236368e600ed4a2b8a8769829ba7620b,
title = "Tight junctions: is there a role in dermatology?",
abstract = "A variety of tight junction (TJ) proteins including claudins, occludin, tricellulin, zonula occludens-proteins and junctional adhesion molecules have been identified in complex localization patterns in mammalian epidermis. Their expression and/or localization is frequently altered in skin diseases including skin tumors. However, our understanding of the function(s) of TJ and TJ proteins in the skin is, even though rapidly increasing, still limited. This review summarizes our current knowledge of the involvement of TJ and TJ proteins in mammalian skin in functions ascribed to TJ in simple epithelia, such as barrier function, polarity, gene expression, proliferation, differentiation, and vesicle transport.",
author = "Nina Kirschner and Claudia Bohner and Susanne Rachow and Johanna Brandner",
year = "2010",
language = "Deutsch",
volume = "302",
pages = "483--493",
journal = "ARCH DERMATOL RES",
issn = "0340-3696",
publisher = "Springer",
number = "7",

}

RIS

TY - JOUR

T1 - Tight junctions: is there a role in dermatology?

AU - Kirschner, Nina

AU - Bohner, Claudia

AU - Rachow, Susanne

AU - Brandner, Johanna

PY - 2010

Y1 - 2010

N2 - A variety of tight junction (TJ) proteins including claudins, occludin, tricellulin, zonula occludens-proteins and junctional adhesion molecules have been identified in complex localization patterns in mammalian epidermis. Their expression and/or localization is frequently altered in skin diseases including skin tumors. However, our understanding of the function(s) of TJ and TJ proteins in the skin is, even though rapidly increasing, still limited. This review summarizes our current knowledge of the involvement of TJ and TJ proteins in mammalian skin in functions ascribed to TJ in simple epithelia, such as barrier function, polarity, gene expression, proliferation, differentiation, and vesicle transport.

AB - A variety of tight junction (TJ) proteins including claudins, occludin, tricellulin, zonula occludens-proteins and junctional adhesion molecules have been identified in complex localization patterns in mammalian epidermis. Their expression and/or localization is frequently altered in skin diseases including skin tumors. However, our understanding of the function(s) of TJ and TJ proteins in the skin is, even though rapidly increasing, still limited. This review summarizes our current knowledge of the involvement of TJ and TJ proteins in mammalian skin in functions ascribed to TJ in simple epithelia, such as barrier function, polarity, gene expression, proliferation, differentiation, and vesicle transport.

M3 - SCORING: Zeitschriftenaufsatz

VL - 302

SP - 483

EP - 493

JO - ARCH DERMATOL RES

JF - ARCH DERMATOL RES

SN - 0340-3696

IS - 7

M1 - 7

ER -