PortalPublikationenThe histone methyltransferase and putative oncoprotein MMSET...

The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors.

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  • Heidi Rye Hudlebusch
  • Eric Santoni-Rugiu
  • Ronald Simon
  • Elisabeth Ralfkiær
  • Henrik Holm Rossing
  • Jens Vilstrup Johansen
  • Mette Jørgensen
  • Guido Sauter
  • Kristian Helin

Beteiligte Einrichtungen

Abstract

Multiple myeloma SET (Suppressor of variegation, Enhancer of zeste, and Trithorax) domain (MMSET) is a histone lysine methyltransferase deregulated in a subgroup of multiple myelomas with the t(4;14)(p16;q32) translocation and poor prognosis. With the aim of understanding, if MMSET can be involved in other types of cancer we investigated the expression of MMSET protein in different types of human tumors.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer9
ISSN1078-0432
StatusVeröffentlicht - 2011
pubmed 21385930