Systems Medicine as an Emerging Tool for Cardiovascular Genetics

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Systems Medicine as an Emerging Tool for Cardiovascular Genetics. / Haase, Tina; Börnigen, Daniela; Müller, Christian; Zeller, Tanja.

in: FRONT CARDIOVASC MED, Jahrgang 3, 2016, S. 27.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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Bibtex

@article{337d9bf9338143298450086d89c76c75,
title = "Systems Medicine as an Emerging Tool for Cardiovascular Genetics",
abstract = "Cardiovascular disease (CVD) is a major contributor to morbidity and mortality worldwide. However, the pathogenesis of CVD is complex and remains elusive. Within the last years, systems medicine has emerged as a novel tool to study the complex genetic, molecular, and physiological interactions leading to diseases. In this review, we provide an overview about the current approaches for systems medicine in CVD. They include bioinformatical and experimental tools such as cell and animal models, omics technologies, network, and pathway analyses. Additionally, we discuss challenges and current literature examples where systems medicine has been successfully applied for the study of CVD.",
keywords = "Journal Article, Review",
author = "Tina Haase and Daniela B{\"o}rnigen and Christian M{\"u}ller and Tanja Zeller",
year = "2016",
doi = "10.3389/fcvm.2016.00027",
language = "English",
volume = "3",
pages = "27",
journal = "FRONT CARDIOVASC MED",
issn = "2297-055X",
publisher = "Frontiers Media S. A.",

}

RIS

TY - JOUR

T1 - Systems Medicine as an Emerging Tool for Cardiovascular Genetics

AU - Haase, Tina

AU - Börnigen, Daniela

AU - Müller, Christian

AU - Zeller, Tanja

PY - 2016

Y1 - 2016

N2 - Cardiovascular disease (CVD) is a major contributor to morbidity and mortality worldwide. However, the pathogenesis of CVD is complex and remains elusive. Within the last years, systems medicine has emerged as a novel tool to study the complex genetic, molecular, and physiological interactions leading to diseases. In this review, we provide an overview about the current approaches for systems medicine in CVD. They include bioinformatical and experimental tools such as cell and animal models, omics technologies, network, and pathway analyses. Additionally, we discuss challenges and current literature examples where systems medicine has been successfully applied for the study of CVD.

AB - Cardiovascular disease (CVD) is a major contributor to morbidity and mortality worldwide. However, the pathogenesis of CVD is complex and remains elusive. Within the last years, systems medicine has emerged as a novel tool to study the complex genetic, molecular, and physiological interactions leading to diseases. In this review, we provide an overview about the current approaches for systems medicine in CVD. They include bioinformatical and experimental tools such as cell and animal models, omics technologies, network, and pathway analyses. Additionally, we discuss challenges and current literature examples where systems medicine has been successfully applied for the study of CVD.

KW - Journal Article

KW - Review

U2 - 10.3389/fcvm.2016.00027

DO - 10.3389/fcvm.2016.00027

M3 - SCORING: Review article

C2 - 27626034

VL - 3

SP - 27

JO - FRONT CARDIOVASC MED

JF - FRONT CARDIOVASC MED

SN - 2297-055X

ER -