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Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes

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Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes. / Melchior, Hanne; Schulz, Holger; Kriston, Levente; Hergert, Anika; Hofreuter-Gätgens, Kerstin; Bergelt, Corinna; Morfeld, Matthias; Koch, Uwe; Watzke, Birgit.

in: PSYCHIAT RES, Jahrgang 238, 30.04.2016, S. 228-35.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Melchior, H, Schulz, H, Kriston, L, Hergert, A, Hofreuter-Gätgens, K, Bergelt, C, Morfeld, M, Koch, U & Watzke, B 2016, 'Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes', PSYCHIAT RES, Jg. 238, S. 228-35. https://doi.org/10.1016/j.psychres.2016.02.046

APA

Melchior, H., Schulz, H., Kriston, L., Hergert, A., Hofreuter-Gätgens, K., Bergelt, C., Morfeld, M., Koch, U., & Watzke, B. (2016). Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes. PSYCHIAT RES, 238, 228-35. https://doi.org/10.1016/j.psychres.2016.02.046

Vancouver

Melchior H, Schulz H, Kriston L, Hergert A, Hofreuter-Gätgens K, Bergelt C et al. Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes. PSYCHIAT RES. 2016 Apr 30;238:228-35. https://doi.org/10.1016/j.psychres.2016.02.046

Bibtex

@article{c4ce87fc86284482b832c0b7a7d92311,
title = "Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes",
abstract = "This study examined symptom change trajectories during inpatient psychotherapy and the association of these changes with long-term outcomes. In an observational multicenter study, weekly measurements of symptom severity were performed during inpatient treatment and 6 months after discharge. The symptom severity was measured using the 18-item scale of the Hamburg Modules for the Assessment of Psychosocial Health. The sample included 576 inpatients (mean age: 43.9 years; 77.6% female; main diagnoses: depressive (57.2%), adjustment (15.8%), anxiety (7.4%), and eating disorders (7.2%); mean treatment duration: 42.0 days). With empirically and clinically informed growth mixture models four subgroups of symptom change were revealed: gradual response (71%), early response (9%), delayed response (5%), and nonresponse (11%). Particularly low educational level, non-employment and chronic disorders were associated with unfavorable symptom courses (non- and delayed response). Long-term outcomes differed systematically across subgroups (p<0.001; η(2)=0.165). The patients who responded early presented the highest rates of clinically significant improvement (43.9%) from admission to follow-up. Nearly all of these patients (92.7%) showed reliable improvement. Due to the high association of symptom change trajectories with long-term outcomes, results may contribute to interventions that are tailored to the needs of patients and may foster longer lasting therapeutic effectiveness.",
keywords = "Adult, Chronic Disease, Female, Follow-Up Studies, Hospitalization, Humans, Inpatients, Male, Mental Disorders, Middle Aged, Psychotherapy, Time Factors, Treatment Outcome, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't",
author = "Hanne Melchior and Holger Schulz and Levente Kriston and Anika Hergert and Kerstin Hofreuter-G{\"a}tgens and Corinna Bergelt and Matthias Morfeld and Uwe Koch and Birgit Watzke",
note = "Copyright {\textcopyright} 2016 Elsevier Ireland Ltd. All rights reserved.",
year = "2016",
month = apr,
day = "30",
doi = "10.1016/j.psychres.2016.02.046",
language = "English",
volume = "238",
pages = "228--35",
journal = "PSYCHIAT RES",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Symptom change trajectories during inpatient psychotherapy in routine care and their associations with long-term outcomes

AU - Melchior, Hanne

AU - Schulz, Holger

AU - Kriston, Levente

AU - Hergert, Anika

AU - Hofreuter-Gätgens, Kerstin

AU - Bergelt, Corinna

AU - Morfeld, Matthias

AU - Koch, Uwe

AU - Watzke, Birgit

N1 - Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

PY - 2016/4/30

Y1 - 2016/4/30

N2 - This study examined symptom change trajectories during inpatient psychotherapy and the association of these changes with long-term outcomes. In an observational multicenter study, weekly measurements of symptom severity were performed during inpatient treatment and 6 months after discharge. The symptom severity was measured using the 18-item scale of the Hamburg Modules for the Assessment of Psychosocial Health. The sample included 576 inpatients (mean age: 43.9 years; 77.6% female; main diagnoses: depressive (57.2%), adjustment (15.8%), anxiety (7.4%), and eating disorders (7.2%); mean treatment duration: 42.0 days). With empirically and clinically informed growth mixture models four subgroups of symptom change were revealed: gradual response (71%), early response (9%), delayed response (5%), and nonresponse (11%). Particularly low educational level, non-employment and chronic disorders were associated with unfavorable symptom courses (non- and delayed response). Long-term outcomes differed systematically across subgroups (p<0.001; η(2)=0.165). The patients who responded early presented the highest rates of clinically significant improvement (43.9%) from admission to follow-up. Nearly all of these patients (92.7%) showed reliable improvement. Due to the high association of symptom change trajectories with long-term outcomes, results may contribute to interventions that are tailored to the needs of patients and may foster longer lasting therapeutic effectiveness.

AB - This study examined symptom change trajectories during inpatient psychotherapy and the association of these changes with long-term outcomes. In an observational multicenter study, weekly measurements of symptom severity were performed during inpatient treatment and 6 months after discharge. The symptom severity was measured using the 18-item scale of the Hamburg Modules for the Assessment of Psychosocial Health. The sample included 576 inpatients (mean age: 43.9 years; 77.6% female; main diagnoses: depressive (57.2%), adjustment (15.8%), anxiety (7.4%), and eating disorders (7.2%); mean treatment duration: 42.0 days). With empirically and clinically informed growth mixture models four subgroups of symptom change were revealed: gradual response (71%), early response (9%), delayed response (5%), and nonresponse (11%). Particularly low educational level, non-employment and chronic disorders were associated with unfavorable symptom courses (non- and delayed response). Long-term outcomes differed systematically across subgroups (p<0.001; η(2)=0.165). The patients who responded early presented the highest rates of clinically significant improvement (43.9%) from admission to follow-up. Nearly all of these patients (92.7%) showed reliable improvement. Due to the high association of symptom change trajectories with long-term outcomes, results may contribute to interventions that are tailored to the needs of patients and may foster longer lasting therapeutic effectiveness.

KW - Adult

KW - Chronic Disease

KW - Female

KW - Follow-Up Studies

KW - Hospitalization

KW - Humans

KW - Inpatients

KW - Male

KW - Mental Disorders

KW - Middle Aged

KW - Psychotherapy

KW - Time Factors

KW - Treatment Outcome

KW - Journal Article

KW - Multicenter Study

KW - Research Support, Non-U.S. Gov't

U2 - 10.1016/j.psychres.2016.02.046

DO - 10.1016/j.psychres.2016.02.046

M3 - SCORING: Journal article

C2 - 27086238

VL - 238

SP - 228

EP - 235

JO - PSYCHIAT RES

JF - PSYCHIAT RES

SN - 0165-1781

ER -