Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements.

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Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements. / Wenzelburger, Roland; Kopper, Florian; Zhang, Bao-Rong; Witt, Karsten; Hamel, Wolfgang; Weinert, Dieter; Kuhtz-Buschbeck, Johann; Gölge, Mukaddes; Illert, Michael; Deuschl, Günther; Krack, Paul.

in: MOVEMENT DISORD, Jahrgang 18, Nr. 10, 10, 2003, S. 1162-1169.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

Wenzelburger, R, Kopper, F, Zhang, B-R, Witt, K, Hamel, W, Weinert, D, Kuhtz-Buschbeck, J, Gölge, M, Illert, M, Deuschl, G & Krack, P 2003, 'Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements.', MOVEMENT DISORD, Jg. 18, Nr. 10, 10, S. 1162-1169. <http://www.ncbi.nlm.nih.gov/pubmed/14534921?dopt=Citation>

APA

Wenzelburger, R., Kopper, F., Zhang, B-R., Witt, K., Hamel, W., Weinert, D., Kuhtz-Buschbeck, J., Gölge, M., Illert, M., Deuschl, G., & Krack, P. (2003). Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements. MOVEMENT DISORD, 18(10), 1162-1169. [10]. http://www.ncbi.nlm.nih.gov/pubmed/14534921?dopt=Citation

Vancouver

Bibtex

@article{67a51607ce364530ae79f329b36b62b3,
title = "Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements.",
abstract = "Deep brain stimulation of the subthalamic nucleus (STN-DBS) reduces akinesia in Parkinson's disease but its impact on fine motor functions was unknown. We assessed the effects of DBS and a levodopa (L-dopa) test on the timing of the precision grip in 18 patients. Improvement on UPDRS-items reflecting hand functions and the shortening of the first phases of the precision grip were more distinct in the L-dopa test than in the pure STN-DBS condition. Other akinesia items and the time for build-up of lifting force were equally improved in both conditions. This suggests that routine STN-DBS might not be equally effective on all aspects of fine motor functions.",
author = "Roland Wenzelburger and Florian Kopper and Bao-Rong Zhang and Karsten Witt and Wolfgang Hamel and Dieter Weinert and Johann Kuhtz-Buschbeck and Mukaddes G{\"o}lge and Michael Illert and G{\"u}nther Deuschl and Paul Krack",
year = "2003",
language = "English",
volume = "18",
pages = "1162--1169",
journal = "MOVEMENT DISORD",
issn = "0885-3185",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Subthalamic nucleus stimulation for Parkinson's disease preferentially improves akinesia of proximal arm movements compared to finger movements.

AU - Wenzelburger, Roland

AU - Kopper, Florian

AU - Zhang, Bao-Rong

AU - Witt, Karsten

AU - Hamel, Wolfgang

AU - Weinert, Dieter

AU - Kuhtz-Buschbeck, Johann

AU - Gölge, Mukaddes

AU - Illert, Michael

AU - Deuschl, Günther

AU - Krack, Paul

PY - 2003

Y1 - 2003

N2 - Deep brain stimulation of the subthalamic nucleus (STN-DBS) reduces akinesia in Parkinson's disease but its impact on fine motor functions was unknown. We assessed the effects of DBS and a levodopa (L-dopa) test on the timing of the precision grip in 18 patients. Improvement on UPDRS-items reflecting hand functions and the shortening of the first phases of the precision grip were more distinct in the L-dopa test than in the pure STN-DBS condition. Other akinesia items and the time for build-up of lifting force were equally improved in both conditions. This suggests that routine STN-DBS might not be equally effective on all aspects of fine motor functions.

AB - Deep brain stimulation of the subthalamic nucleus (STN-DBS) reduces akinesia in Parkinson's disease but its impact on fine motor functions was unknown. We assessed the effects of DBS and a levodopa (L-dopa) test on the timing of the precision grip in 18 patients. Improvement on UPDRS-items reflecting hand functions and the shortening of the first phases of the precision grip were more distinct in the L-dopa test than in the pure STN-DBS condition. Other akinesia items and the time for build-up of lifting force were equally improved in both conditions. This suggests that routine STN-DBS might not be equally effective on all aspects of fine motor functions.

M3 - SCORING: Journal article

VL - 18

SP - 1162

EP - 1169

JO - MOVEMENT DISORD

JF - MOVEMENT DISORD

SN - 0885-3185

IS - 10

M1 - 10

ER -