Stepped, evidence-based and integrated care service model vs. usual care for mental disorders: a randomized controlled trial (RECOVER)

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@article{94b90f70bec143319863b74fe7e56a08,
title = "Stepped, evidence-based and integrated care service model vs. usual care for mental disorders: a randomized controlled trial (RECOVER)",
abstract = "Stepped, evidence-based and integrated care service models have the potential to be used as a reference for mental health services. RECOVER aimed to evaluate cost savings, effectiveness, and cost-effectiveness of such a model within a two arm, assessor- and data analysist-blinded RCT in Hamburg, Germany. Participants aged 16-79 years with mental disorders were randomly assigned either to RECOVER or treatment as usual (TAU). Primary outcomes comprised costs, effectiveness (combined symptoms, functioning, quality of life), and cost-effectiveness, hierarchically ordered. Outcomes were evaluated according to the ITT principle, group differences regarding costs with adjusted generalized linear models, effectiveness with ANCOVA models, and cost-effectiveness with the incremental cost-effectiveness ratio (ICER) and cost-effectiveness acceptability curves (CEACs). Between 1/1/2018 and 12/31/2020, n = 891 were finally included (n = 477 in RECOVER, n = 444 in TAU). RECOVER was associated with significantly lower annual total costs (-22 %), health and social care costs (-25 %) and hospital costs (-50 %). Effectiveness analyses showed a significantly better outcome for RECOVER with the fully imputed data . The CEACs descriptively demonstrated that RECOVER was cost-effective with a probability of >95 %. Treatment in RECOVER resulted in substantial cost reductions with better cost-effectiveness. RECOVER can be recommended as a reference model for comprehensive and integrated mental health services.",
keywords = "Community mental health service, stepped care, coordinated care, mental disorders, severe mental illness, e-mental-health",
author = "Martin Lambert and Hannah K{\"o}nig and Anne Karow and Hans-Helmut K{\"o}nig and Anja Rohenkohl and Daniel Luedecke and Romy Schr{\"o}ter and Constanze Finter and Lisa Tlach and Andreas Schindler and Helmut Peter and Martin Scherer and Claudia Mews and Martin H{\"a}rter and Carola Bindt and Bernd L{\"o}we and Peer Briken and Heike Peper and Michael Schweiger and Mike M{\"o}sko and Thomas Bock and Arno Deister and Correll, {Christoph U.} and Ann-Kathrin Ozga and Amra Pepi{\'c} and Antonia Zapf and J{\"u}rgen Gallinat and Judith Peth and Alexander Konnopka and Holger Schulz",
year = "2024",
month = sep,
doi = "10.1016/j.psychres.2024.116007",
language = "English",
volume = "339",
pages = "116007",
journal = "PSYCHIAT RES",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Stepped, evidence-based and integrated care service model vs. usual care for mental disorders: a randomized controlled trial (RECOVER)

AU - Lambert, Martin

AU - König, Hannah

AU - Karow, Anne

AU - König, Hans-Helmut

AU - Rohenkohl, Anja

AU - Luedecke, Daniel

AU - Schröter, Romy

AU - Finter, Constanze

AU - Tlach, Lisa

AU - Schindler, Andreas

AU - Peter, Helmut

AU - Scherer, Martin

AU - Mews, Claudia

AU - Härter, Martin

AU - Bindt, Carola

AU - Löwe, Bernd

AU - Briken, Peer

AU - Peper, Heike

AU - Schweiger, Michael

AU - Mösko, Mike

AU - Bock, Thomas

AU - Deister, Arno

AU - Correll, Christoph U.

AU - Ozga, Ann-Kathrin

AU - Pepić, Amra

AU - Zapf, Antonia

AU - Gallinat, Jürgen

AU - Peth, Judith

AU - Konnopka, Alexander

AU - Schulz, Holger

PY - 2024/9

Y1 - 2024/9

N2 - Stepped, evidence-based and integrated care service models have the potential to be used as a reference for mental health services. RECOVER aimed to evaluate cost savings, effectiveness, and cost-effectiveness of such a model within a two arm, assessor- and data analysist-blinded RCT in Hamburg, Germany. Participants aged 16-79 years with mental disorders were randomly assigned either to RECOVER or treatment as usual (TAU). Primary outcomes comprised costs, effectiveness (combined symptoms, functioning, quality of life), and cost-effectiveness, hierarchically ordered. Outcomes were evaluated according to the ITT principle, group differences regarding costs with adjusted generalized linear models, effectiveness with ANCOVA models, and cost-effectiveness with the incremental cost-effectiveness ratio (ICER) and cost-effectiveness acceptability curves (CEACs). Between 1/1/2018 and 12/31/2020, n = 891 were finally included (n = 477 in RECOVER, n = 444 in TAU). RECOVER was associated with significantly lower annual total costs (-22 %), health and social care costs (-25 %) and hospital costs (-50 %). Effectiveness analyses showed a significantly better outcome for RECOVER with the fully imputed data . The CEACs descriptively demonstrated that RECOVER was cost-effective with a probability of >95 %. Treatment in RECOVER resulted in substantial cost reductions with better cost-effectiveness. RECOVER can be recommended as a reference model for comprehensive and integrated mental health services.

AB - Stepped, evidence-based and integrated care service models have the potential to be used as a reference for mental health services. RECOVER aimed to evaluate cost savings, effectiveness, and cost-effectiveness of such a model within a two arm, assessor- and data analysist-blinded RCT in Hamburg, Germany. Participants aged 16-79 years with mental disorders were randomly assigned either to RECOVER or treatment as usual (TAU). Primary outcomes comprised costs, effectiveness (combined symptoms, functioning, quality of life), and cost-effectiveness, hierarchically ordered. Outcomes were evaluated according to the ITT principle, group differences regarding costs with adjusted generalized linear models, effectiveness with ANCOVA models, and cost-effectiveness with the incremental cost-effectiveness ratio (ICER) and cost-effectiveness acceptability curves (CEACs). Between 1/1/2018 and 12/31/2020, n = 891 were finally included (n = 477 in RECOVER, n = 444 in TAU). RECOVER was associated with significantly lower annual total costs (-22 %), health and social care costs (-25 %) and hospital costs (-50 %). Effectiveness analyses showed a significantly better outcome for RECOVER with the fully imputed data . The CEACs descriptively demonstrated that RECOVER was cost-effective with a probability of >95 %. Treatment in RECOVER resulted in substantial cost reductions with better cost-effectiveness. RECOVER can be recommended as a reference model for comprehensive and integrated mental health services.

KW - Community mental health service

KW - stepped care

KW - coordinated care

KW - mental disorders

KW - severe mental illness

KW - e-mental-health

U2 - 10.1016/j.psychres.2024.116007

DO - 10.1016/j.psychres.2024.116007

M3 - SCORING: Journal article

C2 - 38865905

VL - 339

SP - 116007

JO - PSYCHIAT RES

JF - PSYCHIAT RES

SN - 0165-1781

ER -