Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse.
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Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse. / Kordes, Uwe; Cheng, Yi-Chuan; Scotting, Paul J.
in: DEV BRAIN RES, Jahrgang 157, Nr. 2, 2, 2005, S. 209-213.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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T1 - Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse.
AU - Kordes, Uwe
AU - Cheng, Yi-Chuan
AU - Scotting, Paul J
PY - 2005
Y1 - 2005
N2 - The SoxE genes, Sox8, Sox9 and Sox10, have been shown to modulate glial specification and differentiation in the peripheral nervous system and spinal cord. However, little is known of their expression during brain development. We have therefore analyzed their expression in developing brain, focused on the cerebellum. In situ hybridization showed a striking degree of temporo-spatial variation in their expression in different glial lineages in both chick and mouse. Sox8 appeared both in oligodendrocytes and astrocytes, Sox9 was more abundant in astrocytes and Sox10 was restricted to later stages of oligodendrocyte development.
AB - The SoxE genes, Sox8, Sox9 and Sox10, have been shown to modulate glial specification and differentiation in the peripheral nervous system and spinal cord. However, little is known of their expression during brain development. We have therefore analyzed their expression in developing brain, focused on the cerebellum. In situ hybridization showed a striking degree of temporo-spatial variation in their expression in different glial lineages in both chick and mouse. Sox8 appeared both in oligodendrocytes and astrocytes, Sox9 was more abundant in astrocytes and Sox10 was restricted to later stages of oligodendrocyte development.
M3 - SCORING: Zeitschriftenaufsatz
VL - 157
SP - 209
EP - 213
IS - 2
M1 - 2
ER -