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Somatic Development in Children with Congenital Heart Defects

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Somatic Development in Children with Congenital Heart Defects. / Poryo, Martin; Paes, Laura Antonia; Pickardt, Thomas; Bauer, Ulrike M M; Meyer, Sascha; Wagenpfeil, Stefan; Abdul-Khaliq, Hashim; German Competence Network for Congenital Heart Defects Investigators.

in: J PEDIATR-US, Jahrgang 192, 01.2018, S. 136-143.e4.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Poryo, M, Paes, LA, Pickardt, T, Bauer, UMM, Meyer, S, Wagenpfeil, S, Abdul-Khaliq, H & German Competence Network for Congenital Heart Defects Investigators 2018, 'Somatic Development in Children with Congenital Heart Defects', J PEDIATR-US, Jg. 192, S. 136-143.e4. https://doi.org/10.1016/j.jpeds.2017.09.059

APA

Poryo, M., Paes, L. A., Pickardt, T., Bauer, U. M. M., Meyer, S., Wagenpfeil, S., Abdul-Khaliq, H., & German Competence Network for Congenital Heart Defects Investigators (2018). Somatic Development in Children with Congenital Heart Defects. J PEDIATR-US, 192, 136-143.e4. https://doi.org/10.1016/j.jpeds.2017.09.059

Vancouver

Poryo M, Paes LA, Pickardt T, Bauer UMM, Meyer S, Wagenpfeil S et al. Somatic Development in Children with Congenital Heart Defects. J PEDIATR-US. 2018 Jan;192:136-143.e4. https://doi.org/10.1016/j.jpeds.2017.09.059

Bibtex

@article{f4a5efc31666409283b00b26eebcced9,
title = "Somatic Development in Children with Congenital Heart Defects",
abstract = "OBJECTIVES: Somatic development is impaired in children with congenital heart defects (CHDs), and head circumference seems to be a strong predictor of neurodevelopmental prognosis. The aim of this study was to generate up-to-date reference values for the somatic development (head circumference, body weight, and length/height) of children with CHDs.STUDY DESIGN: Our study population consisted of all patients included in the PAN study (Pr{\"a}valenz angeborener Herzfehler bei Neugeborenen in Deutschland), which was conducted prospectively over a 3-year study period by the Competence Network for Congenital Heart Defects. All children with mild, moderate, and severe CHDs born in 2006-2009 in Germany were enrolled. For computing of z-scores, only children with the following characteristics were included: appropriate for gestational age, nonsyndromic disease, term or post-term delivery, and no cardiac surgery.RESULTS: There were 2818 patients included. New z-scores for the described somatic measures of children with mild, moderate, and severe CHDs were computed. Comparisons with the KiGGS study (Gesundheit von Kindern und Jugendlichen in Deutschland) and the Berlin Longitudinal Study revealed significantly lower measurements for all measures-most notably in children with severe CHDs and/or cardiac surgery. In our cohort, no catch-up growth was seen after cardiac surgery.CONCLUSION: Children with severe CHDs demonstrated the most abnormal pattern in growth, including head circumference before and after cardiac surgery, which is indicative of accompanying brain pathology unrelated to operative injury.",
keywords = "Body Height/physiology, Body Weight/physiology, Cephalometry, Child Development/physiology, Child, Preschool, Female, Head/growth & development, Heart Defects, Congenital/physiopathology, Humans, Infant, Infant, Newborn, Linear Models, Longitudinal Studies, Male, Prospective Studies, Reference Values",
author = "Martin Poryo and Paes, {Laura Antonia} and Thomas Pickardt and Bauer, {Ulrike M M} and Sascha Meyer and Stefan Wagenpfeil and Hashim Abdul-Khaliq and {German Competence Network for Congenital Heart Defects Investigators} and Rainer Kozlik-Feldmann and Sachweh, {J{\"o}rg Siegmar} and Arlindo Riso",
note = "Copyright {\textcopyright} 2017 Elsevier Inc. All rights reserved.",
year = "2018",
month = jan,
doi = "10.1016/j.jpeds.2017.09.059",
language = "English",
volume = "192",
pages = "136--143.e4",
journal = "J PEDIATR-US",
issn = "0022-3476",
publisher = "Mosby Inc.",

}

RIS

TY - JOUR

T1 - Somatic Development in Children with Congenital Heart Defects

AU - Poryo, Martin

AU - Paes, Laura Antonia

AU - Pickardt, Thomas

AU - Bauer, Ulrike M M

AU - Meyer, Sascha

AU - Wagenpfeil, Stefan

AU - Abdul-Khaliq, Hashim

AU - German Competence Network for Congenital Heart Defects Investigators

AU - Kozlik-Feldmann, Rainer

AU - Sachweh, Jörg Siegmar

AU - Riso, Arlindo

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2018/1

Y1 - 2018/1

N2 - OBJECTIVES: Somatic development is impaired in children with congenital heart defects (CHDs), and head circumference seems to be a strong predictor of neurodevelopmental prognosis. The aim of this study was to generate up-to-date reference values for the somatic development (head circumference, body weight, and length/height) of children with CHDs.STUDY DESIGN: Our study population consisted of all patients included in the PAN study (Prävalenz angeborener Herzfehler bei Neugeborenen in Deutschland), which was conducted prospectively over a 3-year study period by the Competence Network for Congenital Heart Defects. All children with mild, moderate, and severe CHDs born in 2006-2009 in Germany were enrolled. For computing of z-scores, only children with the following characteristics were included: appropriate for gestational age, nonsyndromic disease, term or post-term delivery, and no cardiac surgery.RESULTS: There were 2818 patients included. New z-scores for the described somatic measures of children with mild, moderate, and severe CHDs were computed. Comparisons with the KiGGS study (Gesundheit von Kindern und Jugendlichen in Deutschland) and the Berlin Longitudinal Study revealed significantly lower measurements for all measures-most notably in children with severe CHDs and/or cardiac surgery. In our cohort, no catch-up growth was seen after cardiac surgery.CONCLUSION: Children with severe CHDs demonstrated the most abnormal pattern in growth, including head circumference before and after cardiac surgery, which is indicative of accompanying brain pathology unrelated to operative injury.

AB - OBJECTIVES: Somatic development is impaired in children with congenital heart defects (CHDs), and head circumference seems to be a strong predictor of neurodevelopmental prognosis. The aim of this study was to generate up-to-date reference values for the somatic development (head circumference, body weight, and length/height) of children with CHDs.STUDY DESIGN: Our study population consisted of all patients included in the PAN study (Prävalenz angeborener Herzfehler bei Neugeborenen in Deutschland), which was conducted prospectively over a 3-year study period by the Competence Network for Congenital Heart Defects. All children with mild, moderate, and severe CHDs born in 2006-2009 in Germany were enrolled. For computing of z-scores, only children with the following characteristics were included: appropriate for gestational age, nonsyndromic disease, term or post-term delivery, and no cardiac surgery.RESULTS: There were 2818 patients included. New z-scores for the described somatic measures of children with mild, moderate, and severe CHDs were computed. Comparisons with the KiGGS study (Gesundheit von Kindern und Jugendlichen in Deutschland) and the Berlin Longitudinal Study revealed significantly lower measurements for all measures-most notably in children with severe CHDs and/or cardiac surgery. In our cohort, no catch-up growth was seen after cardiac surgery.CONCLUSION: Children with severe CHDs demonstrated the most abnormal pattern in growth, including head circumference before and after cardiac surgery, which is indicative of accompanying brain pathology unrelated to operative injury.

KW - Body Height/physiology

KW - Body Weight/physiology

KW - Cephalometry

KW - Child Development/physiology

KW - Child, Preschool

KW - Female

KW - Head/growth & development

KW - Heart Defects, Congenital/physiopathology

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Linear Models

KW - Longitudinal Studies

KW - Male

KW - Prospective Studies

KW - Reference Values

U2 - 10.1016/j.jpeds.2017.09.059

DO - 10.1016/j.jpeds.2017.09.059

M3 - SCORING: Journal article

C2 - 29246335

VL - 192

SP - 136-143.e4

JO - J PEDIATR-US

JF - J PEDIATR-US

SN - 0022-3476

ER -