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Skin barrier in atopic dermatitis

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Skin barrier in atopic dermatitis. / Kezic, Sanja; Novak, Natalija; Jakasa, Ivone; Jungersted, Jackob M; Simon, Michel; Brandner, Johanna M; Middelkamp-Hup, Maritza A; Weidinger, Stephan.

in: FRONT BIOSCI-LANDMRK, Jahrgang 19, 01.01.2014, S. 541-556.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kezic, S, Novak, N, Jakasa, I, Jungersted, JM, Simon, M, Brandner, JM, Middelkamp-Hup, MA & Weidinger, S 2014, 'Skin barrier in atopic dermatitis', FRONT BIOSCI-LANDMRK, Jg. 19, S. 541-556.

APA

Kezic, S., Novak, N., Jakasa, I., Jungersted, J. M., Simon, M., Brandner, J. M., Middelkamp-Hup, M. A., & Weidinger, S. (2014). Skin barrier in atopic dermatitis. FRONT BIOSCI-LANDMRK, 19, 541-556.

Vancouver

Kezic S, Novak N, Jakasa I, Jungersted JM, Simon M, Brandner JM et al. Skin barrier in atopic dermatitis. FRONT BIOSCI-LANDMRK. 2014 Jan 1;19:541-556.

Bibtex

@article{25a984bf55e24d2f96bbebd2f62b0baa,
title = "Skin barrier in atopic dermatitis",
abstract = "The skin represents the largest organ of the body and provides a vital interface between the body and the environment. Hereditary and acquired alterations of structural proteins and lipids of the stratum corneum and epidermal tight junctions leading to a diminished skin barrier function are major causative factors for a number of skin diseases, in particular atopic dermatitis (AD). This review summarizes current knowledge on the role of the skin barrier in AD with regard to pathogenesis and treatment, on the relationship between skin barrier abnormalities and immune aberrations, and on potential therapies aimed at repair of the skin barrier. Furthermore recent advances in the genetics of AD will be addressed.",
keywords = "Dermatitis, Atopic, Humans, Intermediate Filament Proteins, Lipids, Skin Absorption, Tight Junctions",
author = "Sanja Kezic and Natalija Novak and Ivone Jakasa and Jungersted, {Jackob M} and Michel Simon and Brandner, {Johanna M} and Middelkamp-Hup, {Maritza A} and Stephan Weidinger",
year = "2014",
month = jan,
day = "1",
language = "English",
volume = "19",
pages = "541--556",
journal = "FRONT BIOSCI-LANDMRK",
issn = "2768-6701",
publisher = "Frontiers in Bioscience",

}

RIS

TY - JOUR

T1 - Skin barrier in atopic dermatitis

AU - Kezic, Sanja

AU - Novak, Natalija

AU - Jakasa, Ivone

AU - Jungersted, Jackob M

AU - Simon, Michel

AU - Brandner, Johanna M

AU - Middelkamp-Hup, Maritza A

AU - Weidinger, Stephan

PY - 2014/1/1

Y1 - 2014/1/1

N2 - The skin represents the largest organ of the body and provides a vital interface between the body and the environment. Hereditary and acquired alterations of structural proteins and lipids of the stratum corneum and epidermal tight junctions leading to a diminished skin barrier function are major causative factors for a number of skin diseases, in particular atopic dermatitis (AD). This review summarizes current knowledge on the role of the skin barrier in AD with regard to pathogenesis and treatment, on the relationship between skin barrier abnormalities and immune aberrations, and on potential therapies aimed at repair of the skin barrier. Furthermore recent advances in the genetics of AD will be addressed.

AB - The skin represents the largest organ of the body and provides a vital interface between the body and the environment. Hereditary and acquired alterations of structural proteins and lipids of the stratum corneum and epidermal tight junctions leading to a diminished skin barrier function are major causative factors for a number of skin diseases, in particular atopic dermatitis (AD). This review summarizes current knowledge on the role of the skin barrier in AD with regard to pathogenesis and treatment, on the relationship between skin barrier abnormalities and immune aberrations, and on potential therapies aimed at repair of the skin barrier. Furthermore recent advances in the genetics of AD will be addressed.

KW - Dermatitis, Atopic

KW - Humans

KW - Intermediate Filament Proteins

KW - Lipids

KW - Skin Absorption

KW - Tight Junctions

M3 - SCORING: Journal article

C2 - 24389202

VL - 19

SP - 541

EP - 556

JO - FRONT BIOSCI-LANDMRK

JF - FRONT BIOSCI-LANDMRK

SN - 2768-6701

ER -