Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.
Beteiligte Einrichtungen
Abstract
Selective inhibition of lymphocyte activation through abrogation of signal 3-cytokine transduction emerges as a new strategy for immunosuppression. This is the first report on the novel Janus kinase (JAK)1/3 inhibitors R507 and R545 for prevention of acute allograft rejection.
Bibliografische Daten
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 7 |
| ISSN | 0041-1337 |
| Status | Veröffentlicht - 2012 |
| pubmed | 22971540 |
|---|
