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Sarcopenia - Endocrinological and Neurological Aspects

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Sarcopenia - Endocrinological and Neurological Aspects. / Stangl, Michaela Katja; Böcker, Wolfgang; Chubanov, Vladimir; Ferrari, Uta; Fischereder, Michael; Gudermann, Thomas; Hesse, Eric; Meinke, Peter; Reincke, Martin; Reisch, Nicole; Saller, Maximilian M; Seissler, Jochen; Schmidmaier, Ralf; Schoser, Benedikt; Then, Cornelia; Thorand, Barbara; Drey, Michael.

in: EXP CLIN ENDOCR DIAB, Jahrgang 127, Nr. 1, 01.2019, S. 8-22.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Stangl, MK, Böcker, W, Chubanov, V, Ferrari, U, Fischereder, M, Gudermann, T, Hesse, E, Meinke, P, Reincke, M, Reisch, N, Saller, MM, Seissler, J, Schmidmaier, R, Schoser, B, Then, C, Thorand, B & Drey, M 2019, 'Sarcopenia - Endocrinological and Neurological Aspects', EXP CLIN ENDOCR DIAB, Jg. 127, Nr. 1, S. 8-22. https://doi.org/10.1055/a-0672-1007

APA

Stangl, M. K., Böcker, W., Chubanov, V., Ferrari, U., Fischereder, M., Gudermann, T., Hesse, E., Meinke, P., Reincke, M., Reisch, N., Saller, M. M., Seissler, J., Schmidmaier, R., Schoser, B., Then, C., Thorand, B., & Drey, M. (2019). Sarcopenia - Endocrinological and Neurological Aspects. EXP CLIN ENDOCR DIAB, 127(1), 8-22. https://doi.org/10.1055/a-0672-1007

Vancouver

Stangl MK, Böcker W, Chubanov V, Ferrari U, Fischereder M, Gudermann T et al. Sarcopenia - Endocrinological and Neurological Aspects. EXP CLIN ENDOCR DIAB. 2019 Jan;127(1):8-22. https://doi.org/10.1055/a-0672-1007

Bibtex

@article{2da3438ee24d4c4ca874a86ba10d665d,
title = "Sarcopenia - Endocrinological and Neurological Aspects",
abstract = "Sarcopenia in geriatric patients is often associated with or even caused by changes of the endocrine and nervous system. The multifactorial pathogenesis of sarcopenia and additional multimorbidity in geriatric patients makes it difficult to study distinct pathogenic pathways leading to sarcopenia. Patients suffering from diabetes, Cushing's syndrome, chronic kidney disease, Klinefelter's syndrome or motor neuron diseases, such as amyotrophic lateral sclerosis for example are known to have impaired muscle property and reduced physical performance. These patients are typically younger and suffer from conditions caused by a known molecular disease mechanism and a peculiar sarcopenic phenotype. Therefore, these sequelae can serve as prototypic disease models to study isolated endocrinological and neurodegenerative causes for sarcopenia. This review focuses on diseases whose etiopathogenesis of muscle impairment is known. The idea is to use these diseases as proof of principles to develop a classification algorithm of sarcopenia in the elderly to make a more mechanism-oriented therapy be possible.",
keywords = "Journal Article, Sarcopenia/diagnosis, Animals, Klinefelter Syndrome/complications, Humans, Cushing Syndrome/complications, Renal Insufficiency, Chronic/complications, Amyotrophic Lateral Sclerosis/complications, Diabetes Mellitus, Type 2/complications",
author = "Stangl, {Michaela Katja} and Wolfgang B{\"o}cker and Vladimir Chubanov and Uta Ferrari and Michael Fischereder and Thomas Gudermann and Eric Hesse and Peter Meinke and Martin Reincke and Nicole Reisch and Saller, {Maximilian M} and Jochen Seissler and Ralf Schmidmaier and Benedikt Schoser and Cornelia Then and Barbara Thorand and Michael Drey",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2019",
month = jan,
doi = "10.1055/a-0672-1007",
language = "English",
volume = "127",
pages = "8--22",
journal = "EXP CLIN ENDOCR DIAB",
issn = "0947-7349",
publisher = "Georg Thieme Verlag KG",
number = "1",

}

RIS

TY - JOUR

T1 - Sarcopenia - Endocrinological and Neurological Aspects

AU - Stangl, Michaela Katja

AU - Böcker, Wolfgang

AU - Chubanov, Vladimir

AU - Ferrari, Uta

AU - Fischereder, Michael

AU - Gudermann, Thomas

AU - Hesse, Eric

AU - Meinke, Peter

AU - Reincke, Martin

AU - Reisch, Nicole

AU - Saller, Maximilian M

AU - Seissler, Jochen

AU - Schmidmaier, Ralf

AU - Schoser, Benedikt

AU - Then, Cornelia

AU - Thorand, Barbara

AU - Drey, Michael

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2019/1

Y1 - 2019/1

N2 - Sarcopenia in geriatric patients is often associated with or even caused by changes of the endocrine and nervous system. The multifactorial pathogenesis of sarcopenia and additional multimorbidity in geriatric patients makes it difficult to study distinct pathogenic pathways leading to sarcopenia. Patients suffering from diabetes, Cushing's syndrome, chronic kidney disease, Klinefelter's syndrome or motor neuron diseases, such as amyotrophic lateral sclerosis for example are known to have impaired muscle property and reduced physical performance. These patients are typically younger and suffer from conditions caused by a known molecular disease mechanism and a peculiar sarcopenic phenotype. Therefore, these sequelae can serve as prototypic disease models to study isolated endocrinological and neurodegenerative causes for sarcopenia. This review focuses on diseases whose etiopathogenesis of muscle impairment is known. The idea is to use these diseases as proof of principles to develop a classification algorithm of sarcopenia in the elderly to make a more mechanism-oriented therapy be possible.

AB - Sarcopenia in geriatric patients is often associated with or even caused by changes of the endocrine and nervous system. The multifactorial pathogenesis of sarcopenia and additional multimorbidity in geriatric patients makes it difficult to study distinct pathogenic pathways leading to sarcopenia. Patients suffering from diabetes, Cushing's syndrome, chronic kidney disease, Klinefelter's syndrome or motor neuron diseases, such as amyotrophic lateral sclerosis for example are known to have impaired muscle property and reduced physical performance. These patients are typically younger and suffer from conditions caused by a known molecular disease mechanism and a peculiar sarcopenic phenotype. Therefore, these sequelae can serve as prototypic disease models to study isolated endocrinological and neurodegenerative causes for sarcopenia. This review focuses on diseases whose etiopathogenesis of muscle impairment is known. The idea is to use these diseases as proof of principles to develop a classification algorithm of sarcopenia in the elderly to make a more mechanism-oriented therapy be possible.

KW - Journal Article

KW - Sarcopenia/diagnosis

KW - Animals

KW - Klinefelter Syndrome/complications

KW - Humans

KW - Cushing Syndrome/complications

KW - Renal Insufficiency, Chronic/complications

KW - Amyotrophic Lateral Sclerosis/complications

KW - Diabetes Mellitus, Type 2/complications

U2 - 10.1055/a-0672-1007

DO - 10.1055/a-0672-1007

M3 - SCORING: Review article

C2 - 30199918

VL - 127

SP - 8

EP - 22

JO - EXP CLIN ENDOCR DIAB

JF - EXP CLIN ENDOCR DIAB

SN - 0947-7349

IS - 1

ER -